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Biology

Ole Isacson: desarrollo de nuevas terapias para la enfermedad de Parkinson

Published: April 29, 2007 doi: 10.3791/189

Summary

Ole Isacson da un panorama general de la enfermedad de Parkinson, sus causas y estrategias terapéuticas, y los avances en la investigación del Parkinson.

References

  1. Chung, C. Y., Seo, H., Sonntag, K. C., Brooks, A., Lin, L., Iasacson, O. Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability. Hum. Mol. Genet. 14, 1709-1725 (2005).
  2. Mendez, I., Sanchez-Pernaute, R., Cooper, O., Vinuela, A., Ferrari, D., Bjoerklund, L., Dagher, A., Isacson, O. Cell type analysis of fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain. 128 (7), 1498-1510 (2005).
  3. Cooper, O., Isacson, O. Intrastiatal Transforming Growth Factor Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons. J. Neurosci. 24 (41), 8924-8931 (2004).
  4. Sanchez-Pernaute, R., Ferree, A., Cooper, O., Yu, M., Brownell, A. L., Isacson, O. Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat mod of Parkinson's disease. Journal of Neuroinflammation. , (2004).
  5. Isacson, O. The production and use of cells as therapeutic agents in neurodegenerative diseases. Lancet Neurology. 2 (7), 417-424 (2003).

Tags

Medicina número 3 la enfermedad de Parkinson la Neurociencia la dopamina las neuronas L-DOPA las células madre trasplante
Ole Isacson: desarrollo de nuevas terapias para la enfermedad de Parkinson
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Isacson, O. Ole Isacson: Development More

Isacson, O. Ole Isacson: Development of New Therapies for Parkinson's Disease. J. Vis. Exp. (3), e189, doi:10.3791/189 (2007).

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