Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Use of In vivo Imaging to Monitor the Progression …
JoVE Journal
Immunology and Infection

A subscription to JoVE is required to view this content.

JoVE Journal Immunology and Infection
Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
Journal (Immunology and Infection)
Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
Isolation of Low Endotoxin Content Extracellular Vesicles Derived from Cancer Cell Lines
Journal (Immunology and Infection)
Isolation of Low Endotoxin Content Extracellular Vesicles Derived from Cancer Cell Lines
 

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Article DOI: 10.3791/50409 • 05:53 min • July 6th, 2013
July 6th, 2013 •
1, 1, 1, 1
1ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Centre de Recherche d'Immunologie et d'Hématologie, Université de Strasbourg

Chapters

Summary
Automatic Translation

Human Cytomegalovirus (HCMV) infection of neonates represents an important cause of mental retardation, yet the molecular events leading to virus-induced pathogenesis are still poorly understood. To investigate the dynamics of brain infection, we adapted whole-animal in vivo imaging to perform time-course analysis of neonates infected with a luciferase-recombinant virus.

Tags

In Vivo Imaging Experimental Mouse Cytomegalovirus Infection Neonates Human Cytomegalovirus HCMV HHV-5 Immune-compromised Individuals Congenital Infection Neonatal Infection Developing Brain Neurological Damage Deafness Mental Retardation Therapeutic Options Vaccine Antiviral Therapy Central Nervous System (CNS) Molecular Events Autopsy Rhesus Macaque CMV CMV Pathogenesis Intracranial Inoculation Procedure Ethical Considerations Newborn Mice Mouse Cytomegalovirus (MCMV) Balb/c Neonates Neurons Glial Cells
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter