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Journal / Bioengineering / Modeling Kræft i æggestokkene flercellede…
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JoVE Journal Bioengineering
Modeling Kræft i æggestokkene flercellede Sfæroide Behavior i en dynamisk 3D Peritoneal Microdevice
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Modeling Kræft i æggestokkene flercellede Sfæroide Behavior i en dynamisk 3D Peritoneal Microdevice

Article DOI: 10.3791/55337-v • 11:34 min • February 18th, 2017
February 18th, 2017 •
*1, *1, *2, 2, 3, 3, 4, 2, 1
1School of Biological Sciences, University of Hong Kong, 2Department of Mechanical Engineering, University of Hong Kong, 3Department of Medicine, University of Hong Kong, 4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong
* These authors contributed equally

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At studere i æggestokkene tumor progression i en fysiologisk relevant model, flercellede spheroids blev dyrket i en microdevice under simuleret væske flow. Denne dynamiske 3D-model emulerer intraperitoneal miljø med de cellulære og mekaniske komponenter, hvor kræft i æggestokkene metastaser forekommer.

Tags

Bioengineering ovariecancer mikrofluidik forskydningsspænding peritoneale mesotelceller multicellulære sfæroider 3D kultur co-kultur
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