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Ekspresjon av eksogen cytokin i pasient-avledede xenotransplantater via injeksjon med en cytokin-transduced stromcellelinje
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Ekspresjon av eksogen cytokin i pasient-avledede xenotransplantater via injeksjon med en cytokin-transduced stromcellelinje

Article DOI: 10.3791/55384-v • 12:58 min • May 10th, 2017
May 10th, 2017 •
1, 1, 1, 2, 3, 1, 1, 1
1Department of Pathology and Human Anatomy, Loma Linda University, 2Department of Basic Sciences, Loma Linda University, 3Department of Medicine, Loma Linda University

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Beskrevet her er en metode for fremstilling av eksogent cytokin i pasient-avledede xenograftmus (PDX) -mus via ukentlig intraperitoneal injeksjon av en cytokin-transduced stromalcellelinje. Denne metoden utvider bruken av PDX og gir muligheten for forbigående eller vedvarende eksogen cytokinlevering i en rekke PDX-modeller.

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Medisin utgave 123 xenograft preklinisk modell leukemi pasient-avledet xenografts (PDX), tymisk stromal lymfopoietin (TSLP)
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