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单一和重复轻度创伤性脑损伤的小鼠模型

JoVE Journal
Medicine

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JoVE Journal Medicine

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury

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单一和重复轻度创伤性脑损伤的小鼠模型

DOI:

10.3791/55713-v

•

04:19 min

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June 20, 2017

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Bevan S. Main, Stephanie S. Sloley, Sonia Villapol, David N. Zapple, Mark P. Burns

¹Laboratory for Brain Injury and Dementia, Department of Neuroscience,Georgetown University Medical Center, ²University Information Systems, Division of Research Technologies,Georgetown University

Chapters

00:05Title
00:50Mouse Traumatic Brain Injury (mTBI) Apparatus Impaction
02:52Results: Representative Effects of Single and Repeat mTBIs
03:59Conclusion

Summary

Automatic Translation

运动员每年吸收数百次轻度创伤性脑损伤（mTBI）/脑震荡;然而，这些对大脑的后果不甚了解。因此，单次和重复性mTBI的动物模型始终如一地复制临床相关症状，为进一步研究mTBI和脑震荡提供了手段。

Tags

Mouse Model Traumatic Brain Injury TBI Mild Traumatic Brain Injury MTBI Concussion Sub-concussive Injury Repetitive Head Impacts Pneumatic Impactor Loss Of Consciousness Righting Reflex Ambulation

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