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Journal / Bioengineering / Engenharia de tecidos tridimensionais alinhado…
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JoVE Journal Bioengineering
Engenharia de tecidos tridimensionais alinhado Astrocyte redes para recapitular os mecanismos do desenvolvimento e facilitar a regeneração do sistema nervoso
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Engenharia de tecidos tridimensionais alinhado Astrocyte redes para recapitular os mecanismos do desenvolvimento e facilitar a regeneração do sistema nervoso

Article DOI: 10.3791/55848-v • 08:56 min • January 10th, 2018
January 10th, 2018 •
*1,2,3, *1,2,4, 1,2,4, 1,2, 1,5, 1,5, 1,2,4, 1,2,5
1Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2Center for Neurotrauma, Neurodegeneration & Restoration, Michael J. Crescenz Veterans Affairs Medical Center, 3School of Biomedical Engineering, Drexel University, 4Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 5Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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Vamos mostrar o desenvolvimento de feixes Self montados, tridimensionais do somata hamartomas alinhado longitudinalmente e processos dentro de um invólucro de biomaterial romance. Estas engenharia "vida andaimes", exibindo o diâmetro do mícron-escala ainda estendendo centímetros de comprimento, pode servir como teste-camas para estudar os mecanismos do desenvolvimento neurológico ou facilitar Epilepsias pelo diretor de migração neuronal e/ou axonal Pathfinding.

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Bioengenharia questão 131 tecido Neural de engenharia vida andaimes neurotrauma Epilepsias migração celular pioneiro do axónio redes astrocyte células-tronco neurais
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