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Journal / Immunology and Infection / Misurazione di deformabilità e l'eterogeneità…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Misurazione di deformabilità e l'eterogeneità delle cellule rosse nel sangue di ektacitometria
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Misurazione di deformabilità e l'eterogeneità delle cellule rosse nel sangue di ektacitometria

Article DOI: 10.3791/56910-v • 09:12 min • January 12th, 2018
January 12th, 2018 •
*1, *2, 2, 3, 4, 4, 1,5, 6, 3, 2
1Department of Pediatrics, Saint Louis University School of Medicine, 2Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 3Molecular and Clinical Hematology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 4Sickle Cell Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 5Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, 6Red Cell Physiology Laboratory, New York Blood Center
* These authors contributed equally

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Qui vi presentiamo le tecniche per misurare la deformabilità del globulo rosso ed eterogeneità cellulare di ektacitometria. Queste tecniche sono applicabili a indagini generali di deformabilità del globulo rosso e indagini specifiche di malattie del sangue caratterizzate dalla presenza di globuli rossi sia rigidi sia deformabili in circolazione, quali anemia falciforme.

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Immunologia problema 131 emoglobina fetale ektacitometria gradiente osmotico dell'eritrocito deformabilità anemia falciforme distorsione di diffrazione
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