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Infección crónica por salmonela fibrosis intestinal inducida

Article DOI: 10.3791/60068-v • 08:40 min • September 22nd, 2019
September 22nd, 2019 •
1, 1, 1, 1
1The Biomedical Research Centre, University of British Columbia

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Este protocolo describe un modelo de ratón de fibrosis intestinal impulsada por Salmonella que se asemeja a las principales señas de identidad patológicas de la enfermedad de Crohn, incluida la inflamación transmural y la fibrosis. Este método se puede utilizar para evaluar los factores de huésped que alteran los resultados fibroticos utilizando ratones mutantes mantenidos en un fondo genético C57Bl/6.

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Inmunología e infección número 151 fibrosis Salmonella,enfermedad inflamatoria intestinal enfermedad de Crohn enfermedad crónica ratón
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