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Slicing og culturing gris hjerter under fysiologiske forhold
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Slicing og culturing gris hjerter under fysiologiske forhold

Article DOI: 10.3791/60913-v • 07:54 min • March 20th, 2020
March 20th, 2020 •
*1, *1, 1, 1, 2, 2, 2, 2, 1, 1,3,4,5,6
1Institute of Molecular Cardiology, Department of Medicine, University of Louisville, 2Department of Bioengineering, University of Louisville, 3Diabetes and Obesity Center, Department of Medicine, University of Louisville, 4Department of Pharmacology and Toxicology, University of Louisville, 5Institute of Cardiovascular Sciences, University of Manchester, 6Faculty of Pharmacy, Zagazig University
* These authors contributed equally

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Denne protokollen beskriver hvordan å skjære og kultur hjertevev under fysiologiske forhold i 6 dager. Dette kultursystemet kan brukes som en plattform for å teste effekten av nye hjertesvikt terapeutiske samt pålitelig testing av akutt kardiotoksisitet i en 3D hjertemodell.

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Medisin Utgave 157 genterapi kardiotoksisitet hjerte elektrisk stimulering kalsium elektrofysiologi biomimetisk kultur farmakologi
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