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Journal / Biology / C. 예쁜꼬마선충에서 RAN 펩타이드 독성…
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C. 예쁜꼬마선충에서 RAN 펩타이드 독성 측정
One and Two-Step Method of Rat Neutrophil Isolation for Harvesting Neutrophil Extracellular Traps (NETs)
Journal (Biology)
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Detection of Protein Interactions in Plant using a Gateway Compatible Bimolecular Fluorescence Complementation (BiFC) System
Journal (Biology)
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C. 예쁜꼬마선충에서 RAN 펩타이드 독성 측정

Article DOI: 10.3791/61024-v • 10:49 min • April 30th, 2020
April 30th, 2020 •
1, 2, 2, 1,2
1Graduate Program in Cell Biology and Molecular Physiology, University of Pittsburgh, 2Department of Pediatrics, University of Pittsburgh School of Medicine

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반복-관련 비-ATG 의존적 번역 제품은 여러 반복 확장 기반 질병의 새로운 병원성 특징이다. 기재된 프로토콜의 목적은 모델 시스템 C. elegans에서행동 및 세포 분석술을 사용하여 이들 펩티드에 의한 독성을 평가하는 것이다.

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생물학 문제 158 신경 변성 ALS 헌팅턴병 C9orf72 프로테독성 반복 확장 장애
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