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Journal / Immunology and Infection / Establecer un modelo de córnea ex vivo porcina…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Establecer un modelo de córnea ex vivo porcina para estudiar tratamientos farmacológicos contra la queratitis bacteriana
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Establecer un modelo de córnea ex vivo porcina para estudiar tratamientos farmacológicos contra la queratitis bacteriana

Article DOI: 10.3791/61156-v • 09:22 min • May 12th, 2020
May 12th, 2020 •
1,2, 3, 4, 1,5, 3, 1,6, 1,7, 1,2
1Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms (SCARAB), University of Sheffield, 2Department of Chemical and Biological Engineering, University of Sheffield, 3Hyderabad Eye Research Foundation, L V Prasad Eye Institute, 4Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, 5Department of Molecular Biology and Biotechnology, University of Sheffield, 6Department of Materials Science and Engineering, University of Sheffield, 7Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield

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Este artículo describe un protocolo paso a paso para establecer un modelo ex vivo porcino de queratitis bacteriana. Pseudomonas aeruginosa se utiliza como organismo prototípico. Este modelo innovador imita la infección in vivo, ya que la proliferación bacteriana depende de la capacidad de la bacteria para dañar el tejido corneal.

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Inmunología e Infección Número 159 Pseudomonas aeruginosa,queratitis córnea ex vivo ojo porcino
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