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Neuroscience

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JoVE Journal Neuroscience
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Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Article DOI: 10.3791/61352-v • 08:37 min • December 22nd, 2020
December 22nd, 2020 •
1, 1
1Department of Bioengineering, Rice University

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This protocol delineates steps necessary for the gene delivery through focused ultrasound blood brain barrier (BBB) opening, evaluation of the resulting gene expression, and measurement of neuromodulation activity of chemogenetic receptors through histological tests.

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