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Journal / Immunology and Infection / 혈청형 1 Streptococcus pneumoniae 균주 519/43에서 돌연변이…
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Immunology and Infection

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JoVE Journal Immunology and Infection
혈청형 1 Streptococcus pneumoniae 균주 519/43에서 돌연변이 구성
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혈청형 1 Streptococcus pneumoniae 균주 519/43에서 돌연변이 구성

Article DOI: 10.3791/61594-v • 06:06 min • September 11th, 2020
September 11th, 2020 •
1, 2, 3, 2, 1
1Faculty of Infections and Tropical Diseases, Department of Infection Biology, London School of Hygiene and Tropical Medicine, 2Division of Medicine, University College London, 3Division of Infection and Immunity, University College London UCL

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여기에서 우리는 DNA와 자살 플라스미드를 자연적으로 획득하는 능력을 사용하여 유전자 변형될 수 있는 S. pneumoniae 혈청형 1 균주 519/43에 대해 설명합니다. 원리의 증거로서, pneumolysin (ply) 유전자의 동종 돌연변이가 만들어졌다.

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면역학 및 감염 제 163 호 혈청 형 1 S. 폐렴 돌연변이 유발 자연 능력 수막염 벨트
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