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JoVE Journal Cancer Research
Coltura di organoidi del cancro della vescica come strumenti di medicina di precisione
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Coltura di organoidi del cancro della vescica come strumenti di medicina di precisione

Article DOI: 10.3791/63192-v • 08:39 min • December 28th, 2021
December 28th, 2021 •
1,2,3,4, 1,2,3,4,5, 1,4, 1,4,5, 1,2, 1,2, 1,2,4, 1,2,3,4, 1,2,3, 1,2, 1,2, 1,2,3,4, *1,2,3,4,5, *1,2,3,4
1School of Biomedical Sciences, Faculty of Health, Queensland University of Technology (QUT) at Translational Research Institute, 2Queensland Bladder Cancer Initiative (QBCI), 3Centre for Personalised Analysis of Cancers (CPAC), 4Australian Prostate Cancer Research Centre - Queensland, 5Department of Urology, Princess Alexandra Hospital
* These authors contributed equally

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Gli organoidi derivati dal paziente (DOP) sono un potente strumento nella ricerca traslazionale sul cancro, che riflette sia l'eterogeneità genetica che fenotipica della malattia e la risposta alle terapie antitumorali personalizzate. Qui, viene dettagliato un protocollo consolidato per generare DOP di carcinoma della vescica primario umano in preparazione per la valutazione delle analisi fenotipiche e delle risposte ai farmaci.

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Ricerca sul cancro numero 178
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