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En lille dyremodel af Ex Vivo Normothermic lever Perfusion
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En lille dyremodel af Ex Vivo Normothermic lever Perfusion

Article DOI: 10.3791/57541-v • 08:32 min • June 27th, 2018
June 27th, 2018 •
1,2, 1, 1,2, 1,2, 1, 1, 3, 4, 2, 1,3, 1,2
1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, 4Department of Medicine, Ohio State University Wexner Medical Center

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Der mangler en væsentlig lever donor, og kriterier for leveren er blevet udvidet. Normothermic ex vivo lever perfusion (NEVLP) er blevet udviklet for at evaluere og redigere organfunktion. Denne undersøgelse viser en rotte model af NEVLP og tester pegyleret-katalase, evne til at afbøde lever bevarelse skade.

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Medicin sag 136 Normothermic ex vivo lever perfusion NEVLP marginale organer udvidet kriterier donorer små dyremodel gnavere rotte
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