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Find video protocols related to scientific articles indexed in Pubmed.
Prognostic value of epidermal growth factor receptor mutations in resected non-small cell lung cancer: a systematic review with meta-analysis.
PLoS ONE
PUBLISHED: 08-27-2014
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The prognostic value of epidermal growth factor receptor (EGFR) mutations in resected non-small cell lung cancer (NSCLC) remains controversial. We performed a systematic review with meta-analysis to assess its role.
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Sunitinib combined with transarterial chemoembolization versus transarterial chemoembolization alone for advanced-stage hepatocellular carcinoma: a propensity score matching study.
Tumour Biol.
PUBLISHED: 08-05-2014
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Sunitinib is a multitargeted tyrosine kinase inhibitor with antitumor and antiangiogenic activity. The aim of this study was to compare the efficacy of sunitinib combined with transarterial chemoembolization (TACE) versus TACE alone for treating patients with advanced-stage hepatocellular carcinoma (HCC). Of 103 patients with advanced-stage HCC, 38 (36.9 %) received TACE combined with sunitinib therapy (combined group) and the remaining 65 patients (63.1 %) received TACE alone (monotherapy group). The primary endpoint was overall survival (OS) and the secondary endpoints were time to progression (TTP) and treatment-related adverse events. Propensity score-based methods were used to minimize bias. The response rate was 15.8 % (6 of 38 patients) in the combined group and 10.8 % (7 of 65 patients) in the monotherapy group (P?=?0.031). The median OS and TTP in the combined group were longer than those in the monotherapy group (OS, 8.8 vs 6.3 months; P?=?0.029 and TTP, 3.9 vs 2.5 months; P?=?0.002). In the propensity score-matched cohort (38 pairs), the median OS in the combined group was significantly longer than that in the monotherapy group (8.8 vs 6.5 months, respectively; P?=?0.044), and the median TTP was also longer in the combined group (3.9 vs 2.6 months, respectively; P?=?0.003). Significant prognostic factors for OS by multivariate analysis included the use of sunitinib, Child-Pugh scores, vascular invasion, distant organ metastasis, and serum AFP level. This study suggests that sunitinib plus TACE are superior to TACE alone with respect to OS and TTP in patients with advanced-stage HCC.
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A randomized phase II study of recombinant human endostatin plus gemcitabine/cisplatin compared with gemcitabine/cisplatin alone as first-line therapy in advanced non-small-cell lung cancer.
Invest New Drugs
PUBLISHED: 01-03-2011
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Studies indicate that recombinant human endostatin (rh-endostatin) can inhibit tumor endothelial cell proliferation, angiogenesis, and tumor growth. This study assessed the efficacy of the combination of standard gemcitabine plus cisplatin chemotherapy with rh-endostatin in patients with non-small-cell lung cancer (NSCLC).
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A pilot study of irinotecan combined with 5-fluorouracil and leucovorin for the treatment of Chinese patients with locally advanced and metastatic gastric cancer.
Tumori
PUBLISHED: 10-28-2009
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The FOLFIRI regimen was evaluated for its anti-tumor activity and toxicity in Chinese patients with locally advanced and metastatic gastric cancer.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.