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Find video protocols related to scientific articles indexed in Pubmed.
Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma.
PLoS ONE
PUBLISHED: 07-23-2011
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MYC is a key transcription factor involved in central cellular processes such as regulation of the cell cycle, histone acetylation and ribosomal biogenesis. It is overexpressed in the majority of human tumors including aggressive B-cell lymphoma. Especially Burkitt lymphoma (BL) is a highlight example for MYC overexpression due to a chromosomal translocation involving the c-MYC gene. However, no genome-wide analysis of MYC-binding sites by chromatin immunoprecipitation (ChIP) followed by next generation sequencing (ChIP-Seq) has been conducted in BL so far.
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Classical Hodgkins lymphoma shows epigenetic features of abortive plasma cell differentiation.
Haematologica
PUBLISHED: 03-10-2011
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Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkins lymphoma. However, little is known regarding epigenetic similarities between cells of classical Hodgkins lymphoma and plasma cell myeloma, both of which share extinction of the gene expression program of mature B cells.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.