JoVE Visualize What is visualize?
Stop Reading. Start Watching.
Advanced Search
Stop Reading. Start Watching.
Regular Search
Find video protocols related to scientific articles indexed in Pubmed.
Thyroid eye disease: a Southeast Asian experience.
Br J Ophthalmol
PUBLISHED: 11-02-2014
Show Abstract
Hide Abstract
To study the demographics, comorbidities, clinical manifestations and treatment methods of thyroid eye disease (TED) in Singapore.
Related JoVE Video
Survey of common practices among oculofacial surgeons in the Asia-Pacific region: Graves' orbitopathy.
Orbit
PUBLISHED: 08-14-2014
Show Abstract
Hide Abstract
A web-based anonymous survey was performed to evaluate practice preferences in the management of Graves' orbitopathy amongst oculofacial surgeons in the Asia-Pacific region.
Related JoVE Video
Survey of Common Practices among Oculofacial Surgeons in the Asia-Pacific Region: Management of Orbital Floor Blowout Fractures.
Craniomaxillofac Trauma Reconstr
PUBLISHED: 03-17-2014
Show Abstract
Hide Abstract
A web-based anonymous survey was performed to assess common practices of oculofacial surgeons in the management of traumatic orbital floor blowout fractures. A questionnaire which contained questions on several controversial topics in the management of orbital floor fractures was sent out via e-mail to 131 oculofacial surgeons in 14 countries in the Asia-Pacific region. A total response rate of 58.3% was achieved from May to December 2012. The preferred time for surgical intervention was within 2 weeks for adult patients, porous polyethylene implant was the most popular choice, and most surgeons preferred the transconjunctival approach. Postoperatively, diplopia was the most commonly encountered complication and most oculofacial surgeons reviewed their patients regularly for up to 12 months. We report the results of the first survey of oculofacial surgeons within the Asia-Pacific region on the management of orbital floor blowout fractures. Compared with previous surveys (from year 2000 to 2004), the duration to surgical intervention was comparable but there was a contrasting change in preferred surgical approach and choice of orbital implant.
Related JoVE Video
Pediatric Thyroid Eye Disease-The Singapore Experience.
Orbit
PUBLISHED: 11-08-2013
Show Abstract
Hide Abstract
Abstract Purpose: To identify the demographics, risk factors, clinical manifestations and treatment methods of pediatric thyroid eye disease (TED) in a South-East Asian tertiary referral practice. Methods: Retrospective case series of all pediatric patients (aged 18 years and under) who presented to our TED clinic between Jan 2006 and Dec 2012. Results: Thirteen patients (26 eyes) were identified - 8 females (61.5%) and 5 males (38.5%), accounting for 6.2% of all TED patients in our practice. Median age was 10.0 years (range, 0.3-18.0). Positive family history was noted in 9 patients (69.2%) and there were no active/passive smokers. Mean follow-up duration was 1.81 years (range, 0-5.2). Common presenting signs included proptosis (92.3%), eyelid retraction (84.6%), acquired epiblepharon (69.2%), corneal erosion (53.8%), and lagophthalmos (53.8%). None had optic neuropathy or strabismus. Mean exophthalmometry was 17.8?mm (SD?±?3.6?mm, range 13.0-27.0). Ten patients (76.9%) had mild disease, 3 patients (23.1%) had moderate disease and none had severe disease. Clinically significant Active disease as defined in adults (VISA Inflammatory Score >4/10), was not observed in any patient. The majority of the patients were treated conservatively. One patient underwent bilateral orbital decompression for severe proptosis, while two patients underwent bilateral lower epiblepharon correction with good outcomes. None required corticosteroids (oral/pulsed). Conclusion: Clinical manifestations in pediatric TED are relatively mild and respond well to conservative therapy. Orbital decompression is rarely required but may be considered in children with severe proptosis. Mean exophthalmometry values are lower in East-Asian pediatric TED as compared to Caucasians. Symptomatic acquired epiblepharon, usually associated with keratopathy, is commonly seen in East-Asian pediatric TED; thus, increased awareness among ophthalmologists and pediatricians should be emphasized.
Related JoVE Video
Survey on the management of orbital and intraocular tumors among oculofacial surgeons in the Asia-Pacific region.
Int Ophthalmol
PUBLISHED: 09-01-2013
Show Abstract
Hide Abstract
A web-based anonymous survey was performed to assess the common practices of oculofacial surgeons in the management of orbital and intraocular tumors in the Asia-Pacific region. The questionnaire comprised a series of questions covering controversial topics sent via email to 131 oculofacial surgeons across 14 countries in the Asia-Pacific region. A total response rate of 61.7 % was achieved from May to December 2012. The most common benign orbital tumor was cavernous hemangioma (39.6 %) and the most common malignant orbital tumor was lymphoma (85.7 %). 40 % of surgeons recommended orbital radiation, for which the most common indications were thyroid eye disease (70.0 %) and malignancy (30.0 %). The most common orbitotomy approach was lateral (79.2 %). Most surgeons (87.1 %) offered enucleation for retinoblastoma, but there was also a significant proportion that offered chemoreduction with transpupillary thermotherapy or cryotherapy (58.1 %). Fewer surgeons offered brachytherapy (16.1 %) and intra-arterial chemotherapy (6.5 %). When performing enucleation for retinoblastoma, 81.8 % of surgeons performed a primary orbital implant placement. The most preferred type of implant was silicone/acrylic (90.2, 90.2 and 87.8 % for elderly, adults and children, respectively). The majority of surgeons used donor sclera (57.5 %) or no wrapping material at all (32.5 %). Almost all surgeons (95.1 %) did not drill and peg the implant for motility. We report the results of the first survey of oculofacial surgeons in the Asia-Pacific region on the management of intraocular and orbital tumors. In comparison with previous surveys performed in the USA and the UK, we found the practice patterns of the Asia-Pacific surgeons to be comparable.
Related JoVE Video
Autoclaved autologous bone graft for orbital reconstruction for recurrent temporal bone orbital osteosarcoma.
J Craniofac Surg
PUBLISHED: 01-26-2013
Show Abstract
Hide Abstract
Post-tumor excision and reconstruction of the craniofacial region is a complex and technically demanding process due to its proximity to numerous vital structures and irregularly shaped bony tissue. As such, novel methods are needed when reconstruction of irregularly shaped structures is necessary. Autoclaving of autologous bone grafts is an established practice in orthopedic and neurosurgical practice, but has only been described twice previously for orbital reconstruction. We performed grafting of an autoclaved autologous bone segment as part of surgery on a 30-year-old man to treat his recurrent temporal osteosarcoma with orbital involvement, which is rare. In addition, we went on to highlight key differences between bone autoclaving and pasteurization, an alternative heat treatment technique, for orbital reconstruction post-tumor excision. Although he suffered a second recurrence 8 months later, there was no evidence of recurrence in the autoclaved bone. To treat his second recurrence, he subsequently underwent a modified eyelid-conjunctiva sparing orbital exenteration, also an uncommonly performed procedure. Also, we subsequently examined the novel technique of a lid-sparing and conjunctiva-sparing orbital exenteration and its benefits. He continues to remain under follow-up.
Related JoVE Video
Undifferentiated carcinoma of the lacrimal sac: case report and review of literature.
Orbit
PUBLISHED: 09-29-2011
Show Abstract
Hide Abstract
A 55-year-old man presented with a 2-year history of right-sided epiphora and was referred to the Oculoplastic services for dacryocystorhinostomy. A 3-month progressive growth of a right medial canthal mass was found. MRI revealed an extraconal, lobulated, homogeneously enhancing mass in the lacrimal sac fossa with globe indentation and displacement supero-temporally. Following a transcanalicular needle biopsy which was suggestive of a carcinoma, he underwent medial orbitectomy and maxillectomy, through a lateral rhinotomy, with removal of puncta and canaliculi after ensuring no regional or systemic spread. The lacrimal sac tumor was encapsulated, extending superiorly above the medial canthal tendon and involving the nasolacrimal duct, and posteriorly along the medial orbital wall. After ensuring surgical margins were cleared of tumor infiltration, orbital reconstruction was performed with titanium plate and nasolabial flap. He has completed adjuvant radiotherapy with no evidence of tumor recurrence at 15 months of follow-up.
Related JoVE Video
Acquired Epiblepharon Treated by Lateral Orbital and fat Decompression.
Middle East Afr J Ophthalmol
PUBLISHED: 05-17-2011
Show Abstract
Hide Abstract
Conventional lid surgery of acquired epiblepharon secondary to increased orbital volume can be result of under correction of the epiblepharon, because the increased orbital volume remains unaddressed. In this case report, we present a case of acquired epiblepharon, secondary to increased orbital volume, treated with orbital decompression.
Related JoVE Video
Acute orbital hemorrhage as a presentation of a lytic bony lesion.
Craniomaxillofac Trauma Reconstr
PUBLISHED: 04-24-2011
Show Abstract
Hide Abstract
A 61-year-old Chinese man presented to the emergency department with a 1-day history of painful swelling of the right eyelid with loss of vision. He had been treated earlier for an isolated pathological fracture of the T7 vertebra from plasmacytoma. Computed tomography was suggestive of superior orbital hematoma with bony erosion of the inner and outer tables of an isolated frontal cell, and urgent drainage of the hematoma resulted in relief of the pain and improvement of the vision. A formal orbitotomy was performed to evacuate the hematoma, followed by combined endoscopic sinus surgery and external anterior frontal table trephine to connect the isolated cell to the frontal sinus. The histology did not show evidence of myeloma, and the orbital hematoma was probably a result of an acute hemorrhage into the mucocele of an isolated cell in the frontal bone. However, in patients with a history of multiple myeloma, it is important to consider lytic bony involvement as the cause of an orbital hemorrhage.
Related JoVE Video
The kidney dish as a template for titanium mesh contouring in supraorbital rim fractures: a simple and effective method.
J. Oral Maxillofac. Surg.
PUBLISHED: 04-05-2011
Show Abstract
Hide Abstract
The supraorbital rims are an integral part of facial esthetics and fractures to this region can result in obvious cosmetic deformities. When there is significant bone loss, using titanium mesh is an effective method of reconstructing the supraorbital rim. Conventional methods of contouring the rim include polyurethane skull models, customized implants, and free-form intraoperative bending of the mesh. Conventional skull models are usually based on an average 6-foot-tall Caucasian man and may not accurately simulate the supraorbital rim in persons of Asian descent. Free-form bending is associated with mesh contour irregularities, leading to palpability and protrusion and to nonanatomic conformation of mesh. The kidney dish, a commonly available implement in the operating room, can be used as a template for reconstruction of the supraorbital rims and this technique is described in the present report.
Related JoVE Video
Bilateral orbital haematomas in an anticoagulated patient with severe H1N1 influenza.
Orbit
PUBLISHED: 02-03-2011
Show Abstract
Hide Abstract
A previously healthy woman was admitted to the intensive care unit (ICU) with severe H1N1 influenza. She had prolonged hospital stay due to multiple complications of critical illness, including pelvic deep vein thrombosis (DVT), which was treated with subcutaneous enoxaparin. The patient was referred to the ophthalmology service for bilateral proptosis. On examination, she had bilateral tense proptosis, worse on the left side with exposure keratopathy. Laboratory tests showed that she had thrombocytopenia and raised activated partial thromboplastin time (APTT). A CT scan revealed well-circumscribed soft tissue density lesions in the superolateral orbits and was reported as bilateral lacrimal gland enlargement. However, based on a clinical suspicion of subperiosteal hematoma collection, a diagnostic tap was performed. Following aspiration of six mls of dark blood from the left superior orbit, there was a reduction of proptosis with improvement in chemosis and resolution of exposure keratopathy. Enoxaparin is one of several antithrombotic agents which are increasingly being used for DVT prophylaxis in severely compromised patients. Furthermore, ICU patients ventilated for prolonged periods are at risk of developing chemosis and exposure keratopathy. Thus, the clinician should maintain a high index of suspicion in identifying subperiosteal hematomas, when managing such cases. The spontaneous bilateral vision threatening subperiosteal hematoma was probably caused by a combination of enoxaparin therapy and prolonged ventilation.
Related JoVE Video
Radiological signs of periorbital trauma - the Singapore experience.
Orbit
PUBLISHED: 10-18-2010
Show Abstract
Hide Abstract
To describe the radiological signs and demographic characteristics of patients who suffered facial trauma in South-East Asia.
Related JoVE Video
Blowout fractures: surgical outcome in relation to age, time of intervention, and other preoperative risk factors.
Craniomaxillofac Trauma Reconstr
PUBLISHED: 09-01-2010
Show Abstract
Hide Abstract
We sought to describe outcome of surgical repair in patients presenting with orbital blowout fractures. This noncomparative, retrospective, consecutive case series reviewed the case notes of 63 consecutive patients who underwent surgery for a blowout fracture between November 1992 and March 2005. Risk factors for motility outcome as well as presence of enophthalmos after surgery were analyzed. Children had earlier surgery than adults (p?
Related JoVE Video
Mydriasis during Orbital Floor Fracture Reconstruction: A Novel Diagnostic and Treatment Algorithm.
Craniomaxillofac Trauma Reconstr
PUBLISHED: 06-24-2010
Show Abstract
Hide Abstract
Orbital floor fractures are the most commonly encountered traumatic fractures in the facial skeleton. Mydriasis that is detected during orbital floor fracture reconstruction may cause significant distress to surgeons, as it may be associated with sinister events such as visual loss. It is not an uncommon problem; previous studies have shown the incidence of mydriasis to be 2.1%. The combination of careful preoperative evaluation and planning, as well as specific intraoperative investigations when mydriasis is encountered, can be immensely valuable in allaying surgeons anxiety during orbital floor fracture reconstruction. In this review article, the authors discuss the common causes of mydriasis and present a novel systematic approach to its diagnostic evaluation devised by our unit that has been successfully implemented since 2008.
Related JoVE Video
Marginal zone B-cell orbital lymphoma with intracranial involvement.
Ophthal Plast Reconstr Surg
PUBLISHED: 05-22-2010
Show Abstract
Hide Abstract
A 40-year-old woman presented to the eye clinic with painless swelling of her right lower eyelid of 2 years duration. Examination revealed severe loss of vision in the right eye with hypoglobus and exotropia. CT showed a diffuse right orbital infiltrative lesion with extension to the brain parenchyma. Histopathology confirmed the diagnosis of orbital marginal zone B-cell lymphoma, which is an indolent type of lymphoma that can be associated with systemic lymphoma, but the intracranial association has not been previously described.
Related JoVE Video
Optimizing muscle biopsy for the diagnosis of mitochondrial myopathy.
Ophthal Plast Reconstr Surg
PUBLISHED: 12-08-2009
Show Abstract
Hide Abstract
To establish a reliable technique for harvesting the orbicularis oculi muscle to facilitate diagnosis of chronic progressive external ophthalmoplegia, a mitochondrial myopathy.
Related JoVE Video
Browlift--a South East Asian experience.
Orbit
PUBLISHED: 11-26-2009
Show Abstract
Hide Abstract
To describe the indications, techniques and outcomes of various browlift procedures in a predominantly East-Asian community.
Related JoVE Video
Epiblepharon in East asian patients: the singapore experience.
Ophthalmology
PUBLISHED: 05-10-2009
Show Abstract
Hide Abstract
To describe the demographics, presenting symptoms, indications for surgery, and surgical outcomes of epiblepharon correction in a tertiary care hospital in Singapore.
Related JoVE Video
A safe and accurate method of assessing the size of implants required in orbital floor reconstruction.
Craniomaxillofac Trauma Reconstr
Show Abstract
Hide Abstract
Many methods to determine the size of an orbital floor implant depend on trial and error. However, this technique is imprecise and the repeated insertion and removal of the implant leads to soft tissue trauma and swelling. A method of measuring orbital floor dimensions intraoperatively using a waterproof paper ruler is presented in this study. This technique has the advantage of being simple, precise, safe, and expedient.
Related JoVE Video
Computer-assisted navigational surgery improves outcomes in orbital reconstructive surgery.
J Craniofac Surg
Show Abstract
Hide Abstract
Orbital reconstruction is a difficult procedure, success of which is dependent on the surgeons experience. The lack of objective methods requires a fair amount of estimation is its execution. This study evaluates the efficacy of Kolibri (BrainLab, Munich, Germany), an intraoperative navigation device, in improving outcomes. From 2004 to 2009, 58 patients with orbital trauma who underwent surgery at the National University Hospital, Singapore, were included in this prospective matched control trial. Twenty-nine consecutive patients underwent surgery with Kolibri. The control group underwent surgery without the device. Both groups were matched for age, sex, orbital wall fracture, preoperative ophthalmologic features, etiology and severity of trauma, surgical approach, and types of implant used. The postoperative follow-up was at 1, 3, 6, and 12 months. For subjective assessment, the postoperative ophthalmologic features, including diplopia, infraorbital hypoesthesia, ophthalmoplegia, and enophthalmos, were compared. At 1, 3, 6, and 12 months, respectively, there were fewer patients with postoperative ophthalmologic complications in the study group (italicized; n = 29) compared with the control group (n = 29; P < 0.05): 12/29 (41%) versus 21/29 (72%), 8/29 (28%) versus 19/29 (66%), 5/29 (17%) versus 15/29 (52%), and 2/29 (7%) versus 12/29 (41%). For objective assessment, using the Kolibri workstation, operative plans were created and fused with postoperative computed tomographic scans. Vertical distances between the actual reconstructed and planned orbital floors were measured. On average, the vertical distance measured from the boundaries of floor defects for patients in the study group was 3.24 mm (95% confidence interval, 1.56-4.91) lower than the control group (P = 0.001). In conclusion, navigation minimizes postoperative complications, reduces the need for repeat procedures, and helps surgeons with planning, execution, and postoperative assessment.
Related JoVE Video
Unusual Merkel cell carcinoma of the eyelid.
Orbit
Show Abstract
Hide Abstract
Merkel cell carcinoma of the eyelid is a rare tumor with less than 100 reported cases worldwide. We describe an unusual presentation of Merkel cell carcinoma of the eyelid in a 60 year old Asian male. He presented with multiple left lower lid conjunctival nodules, intense conjunctival erythema, as well as ipsilateral cervical lymphadenopathy. An incisional biopsy diagnosed him with Merkel cell carcinoma with a PET scan showing distant metastatic disease. He was then treated with chemotherapy. The combination of a presentation of conjunctival nodules and erythema, location in the lower eyelid and the conjunctiva, the presence of metastatic disease on diagnosis as well as an unusual immunohistochemical profile make this an unusual case.
Related JoVE Video
Epidemiology of oculoplastic conditions: the Singapore experience.
Orbit
Show Abstract
Hide Abstract
To study the prevalence of eyelid, lacrimal, orbital conditions in an outpatient and surgical environment in a tertiary care hospital in Singapore.
Related JoVE Video

What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.