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Find video protocols related to scientific articles indexed in Pubmed.
A Review of the Methodological Challenges in Assessing the Cost Effectiveness of Pharmacist Interventions.
Pharmacoeconomics
PUBLISHED: 08-22-2014
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Pharmacists' roles are shifting away from medicines supply and the provision of patient education involving acute medications towards consultation-type services for chronic medications. Determining the cost effectiveness of pharmacist interventions has been complicated by methodological challenges. A critique of 31 economic evaluations carried out alongside comparative studies of pharmacist interventions published between 2003 and 2013 (12 from the UK, six from the USA) found a range of disease-specific and cross-therapeutic interventions targeting both patients and prescribers in a range of settings evaluated through a variety of study designs. Only ten were full economic evaluations, five of which were based on randomized controlled trials (RCTs). The intervention was usually quite well described, but the comparator was not always clearly described, and some interventions are very context specific due to the variability in pharmacist services available in different countries and practice settings. Complex multidirectional aims of most pharmacist interventions have led to many process, intermediate and longer-term outcomes being included in any one study. Quality of resource use and cost data varied. Most incremental cost-effectiveness ratios (ICERs) were generated from process indicators such as errors and adherence, with only four studies reporting cost per quality-adjusted life-year (QALY). Very few studies examined the effect of uncertainty, and methods used were not very clear in some cases. The principal finding from our critique is that poor RCT study design or analysis precludes many studies from finding pharmacist interventions effective or cost effective. We conclude with a set of recommendations for future study design.
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Cost effectiveness of a pharmacist-led information technology intervention for reducing rates of clinically important errors in medicines management in general practices (PINCER).
Pharmacoeconomics
PUBLISHED: 03-19-2014
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We recently showed that a pharmacist-led information technology-based intervention (PINCER) was significantly more effective in reducing medication errors in general practices than providing simple feedback on errors, with cost per error avoided at £79 (US$131). We aimed to estimate cost effectiveness of the PINCER intervention by combining effectiveness in error reduction and intervention costs with the effect of the individual errors on patient outcomes and healthcare costs, to estimate the effect on costs and QALYs.
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Motor and functional recovery after stroke: a comparison between rehabilitation settings in a developed versus a developing country.
BMC Health Serv Res
PUBLISHED: 02-11-2014
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Recovery post stroke is well documented in the field of stroke rehabilitation. The structure and process of rehabilitation are different between developed and developing countries. The aim of the present study was to compare the motor and functional recovery of stroke patients in Germany versus stroke patients receiving rehabilitation in South Africa.
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Long-term prediction of functional outcome after stroke using single items of the Barthel Index at discharge from rehabilitation centre.
Disabil Rehabil
PUBLISHED: 05-21-2013
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Abstract Purpose: To determine the prognostic value of single items of the Barthel Index (BI) at discharge from rehabilitation, in predicting independence in personal activities of daily living (ADL) (BI score ?95/100) at five years after stroke. Method: People with stroke were recruited consecutively from four European rehabilitation centres. BI was assessed on discharge and at five years after stroke. Stepwise multivariate logistic regression analysis was used to determine independent predictors of BI score ?95/100 at five years after stroke. Thereupon, percentage chance of reaching BI???95/100 at five years after stroke was calculated. Results: Data were available for 153 patients. Independence in dressing (odds ratio (OR)?=?5.22, 95% confidence interval (CI)?=?1.85-14.76, p?=?0.002) and bathing (OR?=?8.10, 95% CI?=?3.40-19.32, p?
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Physical therapy activities in stroke, knee arthroplasty, and traumatic brain injury rehabilitation: their variation, similarities, and association with functional outcomes.
Phys Ther
PUBLISHED: 10-14-2011
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The mix of physical therapy services is thought to be different with different impairment groups. However, it is not clear how much variation there is across impairment groups. Furthermore, the extent to which the same physical therapy activities are associated with functional outcomes across different types of patients is unknown.
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Cost of hospitalization for cerebrovascular disorders in Belgium.
Acta Neurol Belg
PUBLISHED: 07-14-2011
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There is only scarce information on the incidence and costs of stroke in Belgium. Knowledge of these figures permits targeted allocation of resources and aids cost efficacy estimates.
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Efficient rehabilitation care for joint replacement patients: skilled nursing facility or inpatient rehabilitation facility?
Med Decis Making
PUBLISHED: 04-12-2011
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There has been lengthy debate as to which setting, skilled nursing facility (SNF) or inpatient rehabilitation facility (IRF), is more efficient in treating joint replacement patients. This study aims to determine the efficiency of rehabilitation care provided by SNF and IRF to joint replacement patients with respect to both payment and length of stay (LOS).
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The development and application of a new tool to assess the adequacy of the content and timing of antenatal care.
BMC Health Serv Res
PUBLISHED: 01-03-2011
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Current measures of antenatal care use are limited to initiation of care and number of visits. This study aimed to describe the development and application of a tool to assess the adequacy of the content and timing of antenatal care.
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Physical and occupational therapy in inpatient stroke rehabilitation: the contribution of therapy extenders.
Am J Phys Med Rehabil
PUBLISHED: 10-22-2010
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To understand the use of therapy extenders in stroke rehabilitation.
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Analysis of rehabilitation activities within skilled nursing and inpatient rehabilitation facilities after hip replacement for acute hip fracture.
Am J Phys Med Rehabil
PUBLISHED: 06-23-2010
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To characterize rehabilitation services in two types of postacute facilities in patients who underwent hip replacement following a hip fracture.
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Black-white disparities in motor function outcomes taking into account patient characteristics, nontherapy ancillaries, therapy activities, and therapy interventions.
Arch Phys Med Rehabil
PUBLISHED: 06-04-2010
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To assess black-white differences in functional outcomes, controlling for patient characteristics, use of nontherapy ancillaries (NTAs), and use of physical (PT) and occupational therapy (OT) activities and interventions.
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Black-white differences in patient characteristics, treatments, and outcomes in inpatient stroke rehabilitation.
Arch Phys Med Rehabil
PUBLISHED: 04-16-2010
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To describe racial differences in patient characteristics, nontherapy ancillaries, physical therapy (PT), occupational therapy (OT), and functional outcomes at discharge in stroke rehabilitation.
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Determinants of the number of antenatal visits in a metropolitan region.
BMC Public Health
PUBLISHED: 04-01-2010
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Antenatal care has a positive effect on pregnancy, both clinically and psychologically, but consensus about the optimal number of antenatal visits is lacking. This study aims to provide insight into the dynamics of the number of antenatal visits a woman receives. Independent effects of predisposing, enabling and pregnancy-related determinants are examined.
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Racial disparities in stroke functional outcomes upon discharge from inpatient rehabilitation facilities.
Disabil Rehabil
PUBLISHED: 02-18-2010
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Analyse racial disparities in clinical outcomes after stroke in inpatient rehabilitation facilities (IRF).
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Use of rehabilitation and other health care services by patients with joint replacement after discharge from skilled nursing and inpatient rehabilitation facilities.
Arch Phys Med Rehabil
PUBLISHED: 08-05-2009
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To compare use of rehabilitation and other health services among patients with knee and hip replacement after discharge from a skilled nursing facility (SNF) or an inpatient rehabilitation facility (IRF).
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Characterizing rehabilitation services for patients with knee and hip replacement in skilled nursing facilities and inpatient rehabilitation facilities.
Arch Phys Med Rehabil
PUBLISHED: 08-05-2009
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To characterize rehabilitation services for patients with knee and hip replacement in 3 types of postacute facilities in the U.S.
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Variations in follow-up services after inpatient stroke rehabilitation: a multicentre study.
J Rehabil Med
PUBLISHED: 07-01-2009
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Care after discharge from inpatient stroke rehabilitation units varies across Europe. The aim of this study was to compare service delivery after discharge.
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The use of a biplot in studying outcomes after stroke.
Neurorehabil Neural Repair
PUBLISHED: 06-04-2009
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This study aimed to unravel the multidimensional profile of stroke outcomes by investigating the global correlation structure of motor, functional, and emotional problems of patients, as well as their caregivers strain, at 6 months after stroke. Potential differential associations based on patients level of functioning on admission to the rehabilitation center were analyzed.
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Predictive social factors in relation to preterm birth in a metropolitan region.
Acta Obstet Gynecol Scand
PUBLISHED: 05-19-2009
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Preterm birth is an important indicator of neonatal wellbeing. Infants born preterm are at higher risk for severe morbidity and mortality. Apart from medical risk factors, social factors are also associated with preterm birth. This study aims to provide knowledge on factors which have a predictive role in relation to preterm birth.
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European comparison of stroke rehabilitation.
Top Stroke Rehabil
PUBLISHED: 05-16-2009
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Our understanding of the components of stroke rehabilitation critical to patients outcomes is limited. Comparing practices and outcomes across countries may give clues to how to improve rehabilitation services.
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Long-term outcomes of joint replacement rehabilitation patients discharged from skilled nursing and inpatient rehabilitation facilities.
Arch Phys Med Rehabil
PUBLISHED: 04-21-2009
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To examine functional and health status outcomes of patients with joint replacement discharged from a skilled nursing facility (SNF) or an inpatient rehabilitation facility (IRF).
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Joint replacement rehabilitation outcomes on discharge from skilled nursing facilities and inpatient rehabilitation facilities.
Arch Phys Med Rehabil
PUBLISHED: 01-15-2009
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To compare functional outcomes at discharge across postacute settings.
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Integrated health impact assessment of travel behaviour: model exploration and application to a fuel price increase.
Environ Int
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Transportation policy measures often aim to change travel behaviour towards more efficient transport. While these policy measures do not necessarily target health, these could have an indirect health effect. We evaluate the health impact of a policy resulting in an increase of car fuel prices by 20% on active travel, outdoor air pollution and risk of road traffic injury. An integrated modelling chain is proposed to evaluate the health impact of this policy measure. An activity-based transport model estimated movements of people, providing whereabouts and travelled kilometres. An emission- and dispersion model provided air quality levels (elemental carbon) and a road safety model provided the number of fatal and non-fatal traffic victims. We used kilometres travelled while walking or cycling to estimate the time in active travel. Differences in health effects between the current and fuel price scenario were expressed in Disability Adjusted Life Years (DALY). A 20% fuel price increase leads to an overall gain of 1650 (1010-2330) DALY. Prevented deaths lead to a total of 1450 (890-2040) Years Life Gained (YLG), with better air quality accounting for 530 (180-880) YLG, fewer road traffic injuries for 750 (590-910) YLG and active travel for 170 (120-250) YLG. Concerning morbidity, mostly road safety led to 200 (120-290) fewer Years Lived with Disability (YLD), while air quality improvement only had a minor effect on cardiovascular hospital admissions. Air quality improvement and increased active travel mainly had an impact at older age, while traffic safety mainly affected younger and middle-aged people. This modelling approach illustrates the feasibility of a comprehensive health impact assessment of changes in travel behaviour. Our results suggest that more is needed than a policy rising car fuel prices by 20% to achieve substantial health gains. While the activity-based model gives an answer on what the effect of a proposed policy is, the focus on health may make policy integration more tangible. The model can therefore add to identifying win-win situations for both transport and health.
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The relationship between antenatal care and preterm birth: the importance of content of care.
Eur J Public Health
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Antenatal care can play an important role in the prevention of preterm birth. Evaluation of antenatal care is usually based on the number of visits rather than the content of care, using tools such as the Adequacy of Prenatal Care Use index. This article presents an analysis of the relation between specific elements of antenatal care and the risk of preterm birth compared with considering the number of visits only.
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Inventory of European databases related to cardiovascular diseases.
Eur. Heart J.
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Under the auspices of the ESC the authors discuss databases for managing CVD.
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Health burden of road traffic accidents, an analysis of clinical data on disability and mortality exposure rates in Flanders and Brussels.
Accid Anal Prev
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Statistics on road traffic accidents (RTAs) mainly come from police records. The police reported RTA statistics however are known to have a large degree of under-registration, underestimating the true risk of being injured in traffic accidents. The use of medical based datasets can provide a more accurate estimate of the actual traffic accident health risk. Exposure-based rates of the actual burden from Flanders and Brussels were calculated, comparing differences between road user, age, gender and type of injury sustained. Minimal Clinical Data (MCD) was selected for the years 2003-2007, as well as data from the mortality statistics. Disability Adjusted Life Years (DALY) were calculated and put into perspective with the passenger kilometres travelled. Motorcyclists followed by bicyclists and pedestrians showed a higher DALY per travelled kilometre (6365, 1724 and 1359 DALY per billion kilometres respectively), compared to 113 DALY per billion kilometres for motor vehicles. In bicyclists and to lesser extent in motorcyclists, the majority of the health burden was attributed to disability following injuries and not fatalities. Also in the other road user categories disability added substantially to the total health loss. The use of medical data and more particular the MCD may be a valuable addition of those RTAs that are missed by the police scope. Although the results are still conservative estimations, an injury-based approach can help to better understand the health problem that road traffic accidents cause.
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Translating road safety into health outcomes using a quantitative impact assessment model.
Inj. Prev.
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The majority of traffic safety policies are limited to preventing mortality. However, non-fatal injuries also impose a significant risk of adverse health. Therefore, both mortality and morbidity outcomes should be included in the evaluation of traffic safety policies. The authors propose a method to evaluate different policy options taking into account both fatalities and serious injuries.
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Five-year mortality and related prognostic factors after inpatient stroke rehabilitation: a European multi-centre study.
J Rehabil Med
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To determine 5-year mortality and its association with baseline characteristics and functional status 6 months post-stroke for patients who received inpatient rehabilitation.
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Content and timing of antenatal care: predisposing, enabling and pregnancy-related determinants of antenatal care trajectories.
Eur J Public Health
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When examining risk factors for inadequate antenatal care, the assessment of antenatal care hardly considers the content and timing of interventions during pregnancy. This study aims to provide information about the importance of predisposing, enabling and pregnancy-related determinants on the received content and timing of antenatal care.
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Prediction of hospitalization duration for acute stroke in Belgium.
Acta Neurol Belg
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We aim to predict the duration of hospitalization for acute stroke in Belgium by evaluating the external validity of the prolonged length of stay (PLOS) score and by formulating a new prediction score that may be better suited for the Belgian healthcare system. This single-center retrospective study is based on data collected prospectively from the departmental stroke registry. To validate the PLOS score, receiver operating characteristic curves were constructed and Hosmer-Lemeshow tests were implemented. Odds ratios were calculated by models of logistic regression, based on predictors of length of stay (LOS) with significance in univariate analyses, and were translated into a new risk score. C-statistics for prediction of LOS ?7 days, LOS ?14 days, and LOS ?30 days using the PLOS score were in the range of 0.6-0.7. Thrombolytic therapy, mortality, and need for institutionalization had a notable negative influence on the discrimination of the PLOS score. Overall, the PLOS score performed better for prediction of LOS ?14 days than for LOS ?7 days and ?30 days. The Belgian length of stay for stroke (BLOSS) score is proposed as a simplified prediction model based only on the NIHSS score and age. The PLOS score showed moderate value for prediction of hospitalization duration for acute stroke in this Belgian cohort. A prediction model based only on age and stroke severity may be a worthy alternative.
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A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis.
Lancet
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Medication errors are common in primary care and are associated with considerable risk of patient harm. We tested whether a pharmacist-led, information technology-based intervention was more effective than simple feedback in reducing the number of patients at risk of measures related to hazardous prescribing and inadequate blood-test monitoring of medicines 6 months after the intervention.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.