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Find video protocols related to scientific articles indexed in Pubmed.
In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology.
Europace
PUBLISHED: 11-02-2014
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The clinical efficacy in preventing the recurrence of atrial fibrillation (AF) is higher for amiodarone than for dronedarone. Moreover, pharmacotherapy with these drugs is less successful in patients with remodelled substrate induced by chronic AF (cAF) and patients suffering from familial AF. To date, the reasons for these phenomena are only incompletely understood. We analyse the effects of the drugs in a computational model of atrial electrophysiology.
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Sex differences in the non-invasive risk stratification and prognosis after myocardial infarction.
J Electrocardiol
PUBLISHED: 08-12-2014
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Women have unfavorable prognosis after myocardial infarction (MI). This text describes sex differences in mortality and in the power of risk predictors in contemporarily-treated MI patients.
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Postextrasystolic blood pressure potentiation predicts poor outcome of cardiac patients.
J Am Heart Assoc
PUBLISHED: 06-05-2014
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Postextrasystolic blood pressure potentiation (PESP), the pulse wave augmentation after an extrasystolic beat, is typically enhanced in heart failure (HF) patients. This study prospectively tested the association of PESP and mortality in cardiac patients.
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Assessment of mean respiratory rate from ECG recordings for risk stratification after myocardial infarction.
J Electrocardiol
PUBLISHED: 02-25-2014
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We recently reported that nocturnal respiratory rate (NRR) predicts non-sudden cardiac death in survivors of myocardial infarction (MI). Here, we present the details of the technique deriving NRR from ECG recordings.
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Sympathetic activity-associated periodic repolarization dynamics predict mortality following myocardial infarction.
J. Clin. Invest.
PUBLISHED: 01-16-2014
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Enhanced sympathetic activity at the ventricular myocardium can destabilize repolarization, increasing the risk of death. Sympathetic activity is known to cluster in low-frequency bursts; therefore, we hypothesized that sympathetic activity induces periodic low-frequency changes of repolarization. We developed a technique to assess the sympathetic effect on repolarization and identified periodic components in the low-frequency spectral range (?0.1 Hz), which we termed periodic repolarization dynamics (PRD).
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Safety and efficacy of different stent types for the endovascular therapy of extracranial vertebral artery disease.
Clin Res Cardiol
PUBLISHED: 11-02-2013
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This study aims to determine safety and efficacy of different stent types for extracranial vertebral artery stenting (EVAS) at a single-center institution.
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Three-dimensional transoesophageal echocardiography for the assessment of clip attachment to the leaflets in percutaneous edge-to-edge repair of the mitral valve.
EuroIntervention
PUBLISHED: 01-31-2013
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Single leaflet clip attachment (SLA) is a prevalent complication in percutaneous edge-to-edge repair of the mitral valve, leading to the recurrence of significant mitral regurgitation. The objective of this retrospective analysis was to evaluate a novel 3-D transoesophageal echocardiographic method for the assessment of clip attachment to the mitral leaflets.
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Heart rate turbulence as risk-predictor after myocardial infarction.
Front Physiol
PUBLISHED: 09-02-2011
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Heart rate turbulence (HRT) is the baroreflex-mediated short-term oscillation of cardiac cycle lengths after spontaneous ventricular premature complexes. HRT is composed of a brief heart rate acceleration followed by a gradual heart rate deceleration. In high risk patients after myocardial infarction (MI) HRT is blunted or diminished. Since its first description in 1999 HRT emerged as one of the most potent risk factors after MI. Predictive power of HRT has been studied in more than 10,000 post-infarction patients. This review is intended to provide an overview of HRT as risk-predictor after MI.
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Reflex and tonic autonomic markers for risk stratification in patients with type 2 diabetes surviving acute myocardial infarction.
Diabetes Care
PUBLISHED: 06-16-2011
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Diabetic postinfarction patients are at increased mortality risk compared with nondiabetic postinfarction patients. In a substantial number of these patients, diabetic cardiac neuropathy already preexists at the time of the infarction. In the current study we investigated if markers of autonomic dysfunction can further discriminate diabetic postinfarction patients into low- and high-risk groups.
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Bivariate phase-rectified signal averaging for assessment of spontaneous baroreflex sensitivity: normalization of the results.
J Electrocardiol
PUBLISHED: 05-25-2011
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Previously proposed technique for assessment of spontaneous baroreflex sensitivity (BRS) based on bivariate phase-rectified signal averaging measures averaged R-R interval (RRI) changes triggered by beat-to-beat increases in systolic blood pressure (SBP). In this study, we investigate a normalized version of the method that relates the averaged RRI changes to the triggering blood pressure changes, thus providing the results in measurement units comparable with existing literature.
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Heart rate deceleration runs for postinfarction risk prediction.
J Electrocardiol
PUBLISHED: 03-07-2011
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A method for counting episodes of uninterrupted beat-to-beat heart rate decelerations was developed.
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Sudden cardiac death after myocardial infarction in patients with type 2 diabetes.
Heart Rhythm
PUBLISHED: 07-12-2010
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Type 2 diabetes mellitus is a well-established risk factor for atherosclerosis, but its contribution to sudden cardiac death (SCD) risk after myocardial infarction (MI) is not well defined.
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Bivariate phase-rectified signal averaging for assessment of spontaneous baroreflex sensitivity: pilot study of the technology.
J Electrocardiol
PUBLISHED: 05-01-2010
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Assessment of spontaneous baroreflex sensitivity (BRS), an index of autonomic function, poses practical challenges. In this pilot study, we propose a novel technique for assessment of spontaneous BRS based on bivariate phase-rectified signal averaging (PRSA). This is an extension of the monovariate PRSA technology used for calculation of deceleration capacity.
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Impact of myocardial salvage assessed by (99m)Tc-sestamibi scintigraphy on cardiac autonomic function in patients undergoing mechanical reperfusion therapy for acute myocardial infarction.
JACC Cardiovasc Imaging
PUBLISHED: 07-08-2009
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The purpose of this study was to analyze the impact of myocardial salvage on cardiac autonomic function in patients undergoing mechanical reperfusion therapy for acute myocardial infarction (MI).
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Risk prediction by heart rate turbulence and deceleration capacity in postinfarction patients with preserved left ventricular function retrospective analysis of 4 independent trials.
J Electrocardiol
PUBLISHED: 04-19-2009
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In the Improved Stratification of Autonomic Regulation-Risk trial, postinfarction patients with severe autonomic failure (SAF)-defined as abnormal heart rate turbulence in the presence of abnormal deceleration capacity (DC)-were at high risk of subsequent death, even if left ventricular function was not particularly compromised. The aim of this study was to investigate SAF as a risk predictor in independent postinfarction cohorts.
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Improved Stratification of Autonomic Regulation for risk prediction in post-infarction patients with preserved left ventricular function (ISAR-Risk).
Eur. Heart J.
PUBLISHED: 04-02-2009
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To investigate the combination of heart rate turbulence (HRT) and deceleration capacity (DC) as risk predictors in post-infarction patients with left ventricular ejection fraction (LVEF) > 30%.
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Bivariate phase-rectified signal averaging--a novel technique for cross-correlation analysis in noisy nonstationary signals.
J Electrocardiol
PUBLISHED: 03-31-2009
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Signals generated by biologic systems are characterized by a high degree of nonstationarities and noise. Phase-rectified signal averaging (PRSA) was shown to be superior to conventional methods in detection of periodicities in biologic signals. Bivariate phase-rectified signal averaging (BPRSA) is an extension of the PRSA-method for analysis of interrelationships between 2 synchronously recorded biologic signals. Here, we review the methodology of the technique and demonstrate its performance in simulated data. As application to biologic data, we use BPRSA to analyze synchronously recorded time series of systolic arterial blood pressure, RR intervals, and respiratory activity.
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Respiratory rate predicts outcome after acute myocardial infarction: a prospective cohort study.
Eur. Heart J.
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Risk stratification after acute myocardial infarction (MI) remains imperfect and new indices are sought that might improve the post-MI risk assessment. In a contemporarily-treated cohort of acute MI patients, we tested whether the respiratory rate provides prognostic information and how this information compares to that of established risk assessment.
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Effects of Renal Sympathetic Denervation on 24-hour Blood Pressure Variability.
Front Physiol
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Background: In patients with arterial hypertension, increased blood pressure (BP) variability contributes to end organ damage independently from mean levels of arterial BP. Increased BP variability has been linked to alterations in autonomic function including sympathetic overdrive. We hypothesized that catheter-based renal sympathetic denervation (RDN) confers beneficial effects on BP variability. Methods and Results: Eleven consecutive patients with therapy-refractory arterial hypertension (age 68.9?±?7.0?years; baseline systolic BP 189?±?23?mmHg despite medication with 5.6?±?2.1 antihypertensive drugs) underwent bilateral RDN. Twenty-four hour ambulatory BP monitoring (ABPM) was performed before RDN and 6?months thereafter. BP variability was primarily assessed by means of standard deviation of 24-h systolic arterial BP (SD(sys)). Secondary measures of BP variability were maximum systolic BP (MAX(sys)) and maximum difference between two consecutive readings of systolic BP (?max(sys)) over 24?h. Six months after RDN, SD(sys), MAX(sys), and ?max(sys) were significantly reduced from 16.9?±?4.6 to 13.5?±?2.5?mmHg (p?=?0.003), from 190?±?22 to 172?±?20?mmHg (p?
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Spontaneous baroreflex sensitivity: prospective validation trial of a novel technique in survivors of acute myocardial infarction.
Heart Rhythm
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Low baroreflex sensitivity (BRS) indicates poor prognosis after acute myocardial infarction. Noninvasive BRS assessment is complicated by nonstationarities and noise in electrocardiogram and pressure signals. Phase-rectified signal averaging is a novel signal processing technology overcoming these problems.
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Severe autonomic failure in moderate to severe aortic stenosis: prevalence and association with hemodynamics and biomarkers.
Clin Res Cardiol
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Severe autonomic failure (SAF) refers to combined abnormalities in reflex and tonic autonomic function. SAF indicates increased risk of death in post-infarction and heart failure patients, but has not been studied in aortic stenosis (AS). Here, we investigated SAF in patients with AS and tested its correlation with hemodynamic and biochemical markers.
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Acute beneficial hemodynamic effects of a novel 3D-echocardiographic optimization protocol in cardiac resynchronization therapy.
PLoS ONE
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Post-implantation therapies to optimize cardiac resynchronization therapy (CRT) focus on adjustments of the atrio-ventricular (AV) delay and ventricular-to-ventricular (VV) interval. However, there is little consensus on how to achieve best resynchronization with these parameters. The aim of this study was to examine a novel combination of doppler echocardiography (DE) and three-dimensional echocardiography (3DE) for individualized optimization of device based AV delays and VV intervals compared to empiric programming.
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Percutaneous edge-to-edge repair of the mitral valve in patients with degenerative vs. functional mitral regurgitation.
Catheter Cardiovasc Interv
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Objectives. To prospectively assess the outcome of percutaneous edge-to-edge repair in patients with degenerative vs. functional mitral regurgitation (MR). Background. The optimal patient population eligible for percutaneous edge-to-edge repair has yet to be defined. Methods. We analyzed 119 patients treated by percutaneous edge-to-edge repair for symptomatic MR, 72 patients with degenerative and 47 patients with functional MR. The primary endpoints were defined as procedural success (MR grade reduction ? 1 grade) as well as a composite endpoint defined as freedom from MR 3+ or 4+, mitral valve reintervention and death 12 months after clip implantation. In patients with successful clip placement we further analyzed MR grade, NYHA functional class, distance in the 6 minute walking test and left ventricular volumes 12 months after clip implantation. Results. The primary success rate of all intended clipping procedures was 83.3% for degenerative and 89.4% for functional MR (P = 0.42). Regarding the composite endpoint we observed an event free survival of 59.7% in patients treated for degenerative MR and 63.8% in patients treated for functional MR (P = 0.73). We observed a highly significant reduction in MR grade as well as improvement in NYHA functional status in both groups 12 months after clip implantation. However, there was a more pronounced MR grade reduction in patients treated for degenerative MR compared to patients treated for functional MR. Conclusions. Percutaneous edge-to-edge repair of the mitral valve is feasible and comparably effective in patients with degenerative and functional MR. © 2013 Wiley Periodicals, Inc.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.