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Find video protocols related to scientific articles indexed in Pubmed.
Internal migration, mental health, and suicidal behaviors in young rural Chinese.
Soc Psychiatry Psychiatr Epidemiol
PUBLISHED: 11-10-2014
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There is a dearth of data on the association of internal migration with mental health in young rural Chinese. This study aims to explore the associations between migrant status, mental health, and suicidal behaviors in young rural Chinese.
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Neuropsychiatric disturbance after aneurysmal subarachnoid hemorrhage.
J Clin Neurosci
PUBLISHED: 02-23-2014
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Although aneurysmal subarachnoid hemorrhage (aSAH) accounts for only 3-5% of all strokes, a high degree of morbidity has been reported in this relatively young subset of patients. Neuropsychiatric disturbance has often been neglected in these reports. We aimed to investigate the pattern and pathological factors of chronic neuropsychiatric disturbance in aSAH patients. This cross-sectional observational four-center study was carried out in Hong Kong. Neuropsychiatric outcome (Neuropsychiatric Inventory Chinese Version [CNPI]) assessments were conducted cross-sectionally 1-4 years after ictus. Pathological factors considered were early brain injury as assessed by admission World Federation of Neurosurgical Societies grade, aneurysm treatment (clipping versus coiling), delayed cerebral infarction, and chronic hydrocephalus. One hundred and three aSAH patients' spouses or caregivers completed the CNPI. Forty-two (41%) patients were reported to have one or more domain(s) of neuropsychiatric disturbance. Common neuropsychiatric disturbance domains included agitation/aggression, depression, apathy/indifference, irritability/lability, and appetite/eating disturbance. Chronic neuropsychiatric disturbance was associated with presence of chronic hydrocephalus. A subscore consisting of the five commonly affected domains seems to be a suitable tool for aSAH patients and should be further validated and replicated in future studies.
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A multidimensional risk factor model for suicide attempts in later life.
Neuropsychiatr Dis Treat
PUBLISHED: 01-01-2014
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Elderly suicide is a public health problem worldwide, and the risk factors are multidimensional. Chronic mental health problems, personality traits, stressful life events, comorbid medical conditions, social isolation, unemployment, and poverty are associated with higher risk for suicide in later life. There was a relative paucity of data on the neurobiological markers of elderly suicide.
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The prevalence of insomnia and its socio-demographic and clinical correlates in older adults in rural China: a pilot study.
Aging Ment Health
PUBLISHED: 04-03-2013
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To investigate the prevalence of insomnia (DIS: difficulty initiating sleep; DMS: difficulty maintaining sleep; and EMA: early morning awakening), its socio-demographic and clinical correlates, and the treatment patterns in older adults in rural China.
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Sleep duration and quality of life in young rural Chinese residents.
Behav Sleep Med
PUBLISHED: 03-05-2013
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The aim of this study was to determine the mean total sleep time (TST) and the relation between sleep duration (short sleep: < 7 hr per day; medium sleep: 7-8 hr per day; and long sleep: > 8 hr per day) and quality of life (QOL) in young Chinese rural residents. A sample of 1,632 participants was recruited in Mianyang, Sichuan province and interviewed. Expected and actual TSTs were asked using standardized questions. QOL was measured with the Chinese version of the World Health Organization Quality of Life Schedule-Brief. In the full sample, the mean expected TST was 8.8 ± 1.3 hr, and the mean actual TST was 8.3 ± 1.4 hr. Multivariate analyses revealed that compared to medium sleepers, short sleepers had lower QOL in the physical, psychological, and environmental domains, whereas long sleepers had higher QOL in the environmental domain. Being short or long sleepers was not associated with more major medical conditions. Given the significant associations between short sleep and poor QOL, more attention should be paid to young Chinese rural residents with short sleep.
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Prevalence of psychological symptoms in contemporary Chinese rural-to-urban migrant workers: an exploratory meta-analysis of observational studies using the SCL-90-R.
Soc Psychiatry Psychiatr Epidemiol
PUBLISHED: 02-22-2013
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(1) To estimate the pooled prevalence of psychological symptoms in Chinese migrant workers (CMWs), as measured using the Symptom Checklist-90-R (SCL-90-R) in observational studies conducted in China, and (2) to explore the potential variables associated with the SCL-90-R Global Severity Index (GSI), the overall mental health indicator of CMWs.
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Mental health system in China: history, recent service reform and future challenges.
World Psychiatry
PUBLISHED: 10-13-2011
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This paper summarizes the history of the development of Chinese mental health system; the current situation in the mental health field that China has to face in its effort to reform the system, including mental health burden, workforce and resources, as well as structural issues; the process of national mental health service reform, including how it was included into the national public health program, how it began as a training program and then became a treatment and intervention program, its unique training and capacity building model, and its outcomes and impacts; the barriers and challenges of the reform process; future suggestions for policy; and Chinese experiences as response to the international advocacy for the development of mental health.
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L-DOPA is incorporated into brain proteins of patients treated for Parkinsons disease, inducing toxicity in human neuroblastoma cells in vitro.
Exp. Neurol.
PUBLISHED: 08-23-2011
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Levodopa (L-DOPA), a close structural analogue of the protein amino acid L-tyrosine, can substitute for L-tyrosine in protein synthesis and be mistakenly incorporated into newly synthesised proteins in vitro. We show that L-DOPA-containing proteins are present in the brain in L-DOPA-treated Parkinsons disease patients and accumulate in specific brain regions. In vitro studies demonstrate that substitution of L-tyrosine residues in proteins with L-DOPA causes protein misfolding and promotes protein aggregation in SH-SY5Y neuroblastoma cells resulting in the appearance of autofluorescent bodies. We show that the presence of L-DOPA-containing proteins causes profound changes in mitochondria and stimulates the formation of autophagic vacuoles in cells. Unlike L-DOPA, which is toxic to cells through its ability to generate radicals, proteins containing incorporated L-DOPA are toxic to SH-SY5Y cells by a mechanism independent of oxidative stress and resistant to antioxidants. These data suggest that the accumulation of L-DOPA-containing proteins in vulnerable cells might negatively impact on cell function.
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Association of insight with sociodemographic and clinical factors, quality of life, and cognition in Chinese patients with schizophrenia.
Compr Psychiatry
PUBLISHED: 04-05-2011
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The aims of this study were to assess insight in Chinese patients with schizophrenia and to identify its relationship with sociodemographic and clinical factors, cognition, and quality of life (QOL).
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Neuropsychiatric symptoms are associated with increased risks of progression to dementia: a 2-year prospective study of 321 Chinese older persons with mild cognitive impairment.
Age Ageing
PUBLISHED: 11-23-2010
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studies have suggested that neuropsychiatric (NP) symptoms influence the development of dementia among older adults. But, the results are inconsistent and there is limited information about NP symptoms in population-based samples.
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Socio-demographic and clinical profiles of paranoid and nonparanoid schizophrenia: a prospective, multicenter study in China.
Perspect Psychiatr Care
PUBLISHED: 11-03-2010
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This study aimed to explore the socio-demographic and clinical characteristics of paranoid and nonparanoid subtypes of schizophrenia.
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Predictors of relapse in Chinese schizophrenia patients: a prospective, multi-center study.
Soc Psychiatry Psychiatr Epidemiol
PUBLISHED: 10-18-2010
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Relapse prevention is the main goal of maintenance treatment in schizophrenia. This study aimed to determine the rate and the socio-demographic and clinical predictors of relapse in Chinese schizophrenia patients following treatment of the acute phase of the illness.
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Prevalence of neuropsychiatric symptoms in chinese older persons with mild cognitive impairment-a population-based study.
Am J Geriatr Psychiatry
PUBLISHED: 09-03-2010
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To estimate the point prevalence and correlates of neuropsychiatric (NP) symptoms among older adults with mild cognitive impairment (MCI) and normal cognition (NC) in a Chinese community.
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Combined clinical and cognitive criteria to identify mild cognitive impairment in a southern chinese community.
Alzheimer Dis Assoc Disord
PUBLISHED: 08-10-2010
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Mild Cognitive Impairment (MCI) is a recognized risk condition for clinical dementia. This paper attempted to explore the applicability of a combined cognitive and clinical approach to identify older Chinese adults at-risk of cognitive decline. Seven hundred forty randomly recruited community dwelling participants (aged 60 or over) were assessed at baseline and 2 years with Clinical Dementia Rating (CDR) and a cognitive battery. Baseline MCI groups were categorized by CDR-MCI, cognitive function (Cog-MCI), and a combined CDR-Cog approach. The cognitive approach adopted the Mayo clinic criteria. For the combined approach, nonamnestic MCI combined CDR 0.5 plus nonmemory cognitive deficits. The overall concordance between CDR and Cognitive test ratings were 65.3% (? =256.4, P<0.001, ?=0.44). With a combined approach, 424(57%) participants were classified as normal. CDR-MCI group had higher cognitive scores compared with MCI groups by other criteria (1 way analysis of variance or ANOVA). At 2 years, the combined CDR-Cog MCI group identified all dementia (N=24) converters although group differences were not significant. Cognitive function and CDR identified participants potentially at-risk for furthermore decline, but exhibited some differences in detection profiles. A combined approach may be more practical in screening for MCI participants with diverse educational and cultural background.
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Cigarette smoking in patients with schizophrenia in China: prospective, multicentre study.
Aust N Z J Psychiatry
PUBLISHED: 04-20-2010
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The aim of the present study was to explore the rate of cigarette smoking and its sociodemographic and clinical characteristics in Chinese schizophrenia patients.
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Gender differences in sociodemographic and clinical characteristic and the quality of life of Chinese schizophrenia patients.
Aust N Z J Psychiatry
PUBLISHED: 04-20-2010
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The aim of the present study was to determine the sociodemographic and clinical correlates of the gender of Chinese schizophrenia outpatients and their impact on patients quality of life (QOL).
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Sex differences in patients with schizophrenia: A prospective, multi-center study.
Psychiatry Res
PUBLISHED: 01-26-2010
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This study aimed to determine sex differences in socio-demographic and clinical characteristics of Chinese schizophrenia patients. In a multi-center, randomized, controlled, longitudinal study, 404 clinically stable patients with schizophrenia were randomly assigned to a maintenance group (optimal therapeutic doses continued throughout the study), a 26-week group (optimal therapeutic doses continued for 26 weeks, followed by a 50% dose reduction maintained until the end of the study), or a 4-week group (optimal therapeutic doses continued for 4 weeks, followed by a 50% dose reduction maintained until the end of the study). Participants were interviewed regularly using standardized assessment instruments, and followed up for 12-26 months. In the univariate analyses, the following factors were significantly associated with the male sex: not married, smoking, younger age, earlier age at onset, higher body mass index (BMI) at baseline, and more severe negative and hostility-excitement symptoms at baseline. The following factors were independently associated with the male sex in the multivariate analyses: not being married, smoking, a higher BMI at baseline, less deterioration in disorganized thoughts (4-week group) and positive symptoms (26-week group) and less increase in BMI in all three treatment groups over the study period. The majority of the sex differences in schizophrenia patients in this study are in accordance with results of previous studies worldwide suggesting that sex differences seen in schizophrenia are not dependent on cultural differences between geographically separate patients.
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Socio-demographic and clinical determinants of quality of life in Chinese patients with schizophrenia: a prospective study.
Qual Life Res
PUBLISHED: 01-05-2010
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The aim of the study was to assess the changes in the quality of life (QOL) of Chinese schizophrenia patients and to identify their predictors over a 1-year follow-up.
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What does psychological autopsy study tell us about charcoal burning suicide--a new and contagious method in Asia?
Suicide Life Threat Behav
PUBLISHED: 12-08-2009
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Charcoal burning suicides in Hong Kong between 2002-2004 in the 15 to 59-year-old age group were investigated using the psychological autopsy method. The psychopathological profiles of charcoal burning suicides (N = 53) were compared against "other suicides" (N = 97). The two groups did not differ significantly in the prevalence of DSM-IV axis I diagnoses with the exception of schizophrenic spectrum disorder which was less frequently associated with charcoal burning suicides. Score on "neuroticism" in the NEO-five Factor Inventory (NEO-FFI) was significantly higher in victims of charcoal burning suicide. There was also a trend toward higher score on "conscientiousness" in the NEO-FFI among charcoal burners than victims of other suicide.
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Modality of physical exercise and cognitive function in Hong Kong older Chinese community.
Int J Geriatr Psychiatry
PUBLISHED: 08-07-2009
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We reported the association between modality of Physical Exercise and cognitive function in 782 older Chinese adults assessed in the second phase of a population survey for dementia in Hong Kong.
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Population-attributable risk of suicide conferred by axis I psychiatric diagnoses in a Hong Kong Chinese population.
Psychiatr Serv
PUBLISHED: 08-04-2009
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This study was conducted to determine the population-attributable risk (PAR) of completed suicide among Hong Kong Chinese with axis I psychiatric diagnoses.
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Five-year stability of ICD-10 diagnoses among Chinese patients presented with first-episode psychosis in Hong Kong.
Schizophr. Res.
PUBLISHED: 06-04-2009
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Diagnostic stability is one measure of predictive validity for psychiatric syndromes. It is an under-studied area in functional psychosis despite its clinical and research implications. We aimed at evaluating the stability of ICD-10 diagnoses in a sample of young people with first-episode psychosis.
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Lifetime prevalence of suicidal ideation, suicide plans and attempts in rural and urban regions of Beijing, China.
Aust N Z J Psychiatry
PUBLISHED: 01-21-2009
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There has been no large-scale survey of suicide-related behaviours including suicidal ideations, plans and attempts in China involving both rural and urban areas and using standardized assessment tools. The aim of the present study was to determine the lifetime prevalence of suicide-related behaviour and its relationship with sociodemographic factors and psychiatric disorders in the rural and urban regions of Beijing, China.
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Suicide attempt and suicidal ideation and their associations with demographic and clinical correlates and quality of life in Chinese schizophrenia patients.
Soc Psychiatry Psychiatr Epidemiol
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This study aimed to examine the prevalence and correlates of lifetime suicide attempts and current suicidal ideation in community-dwelling schizophrenia patients in China.
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Quality of life in community-dwelling patients with schizophrenia in China.
J. Nerv. Ment. Dis.
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The aim of this study was to assess Chinese schizophrenia patients quality of life (QOL) and identify its demographic and clinical correlates. A random sample of 540 community-dwelling schizophrenia patients was interviewed using standardized assessment instruments. The patients basic sociodemographic and clinical data and QOL were collected. Compared with the general population, patients had significantly lower scores in the physical and psychological QOL domains. Multivariate analyses showed that better social support independently predicted higher QOL in all domains, whereas more severe positive symptoms predicted worse psychological and environmental domains. Overall psychopathology predicted both worse physical and psychological domains; depressive symptoms and being married predicted worse physical and social QOL, respectively. Our results suggest that therapeutic and psychosocial interventions alleviating positive and depressive symptoms and improving poor social support and marriage-related problems in Chinese patients with schizophrenia might be of considerable benefit in improving their QOL.
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The prevalence of sleep problems and their socio-demographic and clinical correlates in young Chinese rural residents.
Psychiatry Res
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This study aimed to determine the prevalence of basic forms of sleep disturbance (DIS: difficulty initiating sleep; DMS: difficulty maintaining sleep; and EMA: early morning awakening) as well as insomnia (defined as sleep disturbance accompanied by distress or daily functioning impairment), their socio-demographic and clinical correlates, and the treatment patterns in young Chinese rural people. A sample of 1642 subjects was recruited in Mianyang and interviewed using standardized instruments. Basic socio-demographic and clinical data were collected. The prevalence of at least one type of reported sleep disturbance was 8.0%, while the prevalence of at least one type of insomnia was 2.7%. In multivariate analyses, age between 30 and 34 years, having psychiatric disorders, poorer physical domain of quality of life (QOL), better social QOL domain, depressive symptoms and lower social support were independently associated with more frequent sleep disturbance. At the same time, age between 30 and 34 years, female sex, poorer physical QOL domain, better social QOL domain, depressive symptoms, lower life satisfaction, lower social support and more life events were independently associated with more frequent insomnia. Self-reported sleep disturbances are common among young Chinese residents. The low percentage of treated community residents might suggest a need to promote accessible and easily implemented interventions.
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JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

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In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.