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Find video protocols related to scientific articles indexed in Pubmed.
Atherosclerosis in intracranial, extracranial, and coronary arteries with aortic plaques in patients with ischemic stroke of undetermined etiology.
Int. J. Neurosci.
PUBLISHED: 09-30-2014
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Objective: We investigated the association of cerebral and coronary artery atherosclerosis with the presence, burden and type of atherosclerotic plaques of the aorta (AP) in patients with ischemic stroke of undetermined etiology. Methods: 48 consecutive patients (32 males, mean age 68±11 years) with acute ischemic stroke of unknown etiology after thorough stroke workup were investigated using ECG-gated CT-Angiography (CTA) for the detection of embolic AP. Intima media thickness (IMT), presence of carotid plaques and stenosis ?50% and intracranial stenosis were assessed as parameters of cerebral atherosclerosis, the Agatston score (AS) and coronary artery stenosis ?50% (CAS) in CTA as parameters of coronary atherosclerosis. Plaque burden was classified as mild or severe and plaque types were classified according to their morphology in calcified, non-calcified or mixed. Results: APs were found in 36 patients (75%). AP presence was associated with higher IMT values (p = 0.029), intracranial stenosis (p = 0.047), CAS (p = 0.033) and AS (p = 0.026). Twenty-three of 31 (74.2%) patients with both carotid atherosclerosis and AP revealed plaque calcification (p = 0.041). Ten of 14 (71.4%) patients with AP and intracranial stenosis had calcified plaques (p = 0.030). AP in more than one aortic segment was found in patients with bilateral carotid stenosis ?50% (p = 0.038), intracranial stenosis (p = 0.042), high IMT (p = 0.040) and higher AS (p = 0.019). Conclusions: Aortic atherosclerotic plaques are common in patients with ischemic stroke of undetermined etiology and in particular those with carotid, intracranial and coronary atherosclerosis or high IMT values. In these patients, CTA of aorta should be seriously considered.
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Dynamic Volume Perfusion CT Parameters versus RECIST for the Prediction of Outcome in Lung Cancer Patients Treated with Conventional Chemotherapy.
J Thorac Oncol
PUBLISHED: 09-24-2014
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To compare dynamic volume perfusion CT (dVPCT) parameters with RECIST 1.1 for prediction of therapy response and overall survival (OS) in non-small cell (NSCLC) and small-cell lung cancer (SCLC) patients treated with conventional chemotherapy.
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Prenatal MR imaging of congenital diaphragmatic hernias: association of MR fetal lung volume with the need for postnatal prosthetic patch repair.
Eur Radiol
PUBLISHED: 09-03-2014
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To assess whether the need for postnatal prosthetic patch repair of the diaphragmatic defect in neonates with a congenital diaphragmatic hernia (CDH) is associated with the antenatal measured observed-to-expected magnetic resonance fetal lung volume (o/e MR-FLV).
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CAIPIRINHA-Dixon-TWIST (CDT)-volume-interpolated breath-hold examination (VIBE) for dynamic liver imaging: comparison of gadoterate meglumine, gadobutrol and gadoxetic acid.
Eur J Radiol
PUBLISHED: 08-17-2014
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CAIPIRINHA-Dixon-TWIST (CDT)-VIBE is a robust method for abdominal magnetic resonance imaging providing both high spatial and high temporal resolution. The purpose of this study was to examine the influence of different gadolinium based contrast agents (GBCA) on image quality (IQ) with CDT-VIBE.
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Right ventricular dysfunction, late gadolinium enhancement, and female gender predict poor outcome in patients with dilated cardiomyopathy.
Int. J. Cardiol.
PUBLISHED: 07-31-2014
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Dilated cardiomyopathy (DCM) shows a variable disease course and is associated with significant morbidity and mortality. So far, left ventricular function (LVF) is the major determinant for risk stratification. However, since it has shown to be a poor guide to individual outcome, we studied the prognostic value of cardiovascular magnetic resonance imaging (CMR) parameters, late gadolinium enhancement (LGE) and epicardial adipose tissue (EAT).
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Potential for radiation dose savings in abdominal and chest CT using automatic tube voltage selection in combination with automatic tube current modulation.
AJR Am J Roentgenol
PUBLISHED: 07-24-2014
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The purpose of this study was to evaluate the simultaneous use of automatic tube current modulation (ATCM) and automatic tube voltage selection (ATVS) for abdominal and chest CT examinations regarding radiation dose reduction and image quality.
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Effect of time-of-flight technique on the diagnostic performance of 18F-FDG PET/CT for assessment of lymph node metastases in head and neck squamous cell carcinoma.
J Nucl Med Technol
PUBLISHED: 06-26-2014
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Precise assessment of lymph node metastases is critical to the treatment outcome and overall survival of patients with head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to investigate the effect of time-of-flight (TOF) technique on the diagnostic performance of (18)F-FDG PET/CT for assessment of lymph node metastases in HNSCC patients.
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Zoomed EPI-DWI of the head and neck with two-dimensional, spatially-selective radiofrequency excitation pulses.
Eur Radiol
PUBLISHED: 06-24-2014
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To evaluate the feasibility of zoomed diffusion-weighted EPI (z-EPI) in the head and neck in a healthy volunteer population and to compare to conventional single-shot EPI (c-EPI).
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Closing in on the K Edge: Coronary CT Angiography at 100, 80, and 70 kV-Initial Comparison of a Second- versus a Third-Generation Dual-Source CT System.
Radiology
PUBLISHED: 05-31-2014
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Purpose To prospectively evaluate radiation and contrast medium requirements for performing high-pitch coronary computed tomographic (CT) angiography at 70 kV using a third-generation dual-source CT system in comparison to a second-generation dual-source CT system. Materials and Methods All patients gave informed consent for this institutional review board-approved study. Forty-five patients (median age, 52 years; 27 men) were imaged in high-pitch mode with a third-generation dual-source CT system at 70 kV (n = 15) or with a second-generation dual-source CT system at 80 or 100 kV (n = 15 for each). Tube voltage was based on body mass index: 80 or 70 kV for less than 26 kg/m(2) versus 100 kV for 26-30 kg/m(2). For the 80- and 100-kV protocols, 80 mL of contrast material was injected, versus 45 mL for the 70-kV protocol. Data were reconstructed by using a second-generation iterative reconstruction algorithm for second-generation dual-source CT and a recently introduced third-generation iterative reconstruction algorithm for third-generation dual-source CT. Objective image quality was measured for various regions of interest, and subjective image quality was evaluated with a five-point Likert scale. Results The signal-to-noise ratio of the coronary CT angiography studies acquired with 70 kV was significantly higher (70 kV: 14.3-17.6 vs 80 kV: 7.1-12.9 vs 100 kV: 9.8-12.9; P < .0497) than those acquired with the other two protocols for all coronary arteries. Qualitative image quality analyses revealed no significant differences between the three CT angiography protocols (median score, 5; P > .05). The mean effective dose was 75% and 108% higher (0.92 mSv ± 0.3 [standard deviation] and 0.78 mSv ± 0.2 vs 0.44 mSv ± 0.1; P < .0001), respectively, for the 80- and 100-kV CT angiography protocols than for the 70-kV CT angiography protocol. Conclusion In nonobese patients, third-generation high-pitch coronary dual-source CT angiography at 70 kV results in robust image quality for studying the coronary arteries, at significantly reduced radiation dose (0.44 mSv) and contrast medium volume (45 mL), thus enabling substantial radiation dose and contrast medium savings as compared with second-generation dual-source CT. © RSNA, 2014 Online supplemental material is available for this article.
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MRI-based ratio of fetal lung volume to fetal body volume as a new prognostic marker in congenital diaphragmatic hernia.
AJR Am J Roentgenol
PUBLISHED: 05-23-2014
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The objective of our study was to evaluate the prognostic accuracy of the MRI-based ratio of fetal lung volume (FLV) to fetal body volume (FBV) for predicting survival and the need for extracorporeal membrane oxygenation (ECMO) therapy in fetuses with congenital diaphragmatic hernia (CDH).
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How to measure the right ventricular outflow tract with cardiovascular magnetic resonance imaging: a head-to-head comparison of methods.
Hellenic J Cardiol
PUBLISHED: 04-01-2014
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Structural abnormalities of the right ventricular outflow tract (RVOT) have been described in several clinical conditions. The aim of our study was to prospectively compare the available approaches to measuring the RVOT area and diameter by cardiovascular magnetic resonance imaging (CMR) and establish reference values in healthy volunteers. In addition, we sought to introduce a new algorithm for dedicated RVOT area evaluation determined by the RVOT axis.
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Initial results of a new generation dual source CT system using only an in-plane comb filter for ultra-high resolution temporal bone imaging.
Eur Radiol
PUBLISHED: 03-11-2014
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To prospectively evaluate radiation dose and image quality of a third generation dual-source CT (DSCT) without z-axis filter behind the patient for temporal bone CT.
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Optimization of kiloelectron volt settings in cerebral and cervical dual-energy CT angiography determined with virtual monoenergetic imaging.
Acad Radiol
PUBLISHED: 03-06-2014
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Dual-energy computed tomography (DECT) offers various fields of application, especially in angiography using virtual monoenergetic imaging. The aim of this study was to evaluate objective image quality indices of calculated low-kiloelectron volt monoenergetic DECT angiographic cervical and cerebral data sets compared to virtual 120-kV polyenergetic images.
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Evaluation of Radiation Exposure of Medical Staff During CT-Guided Interventions.
J Am Coll Radiol
PUBLISHED: 02-14-2014
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The purpose of this prospective study was to investigate absolute radiation exposure values and factors that influence radiation exposure of interventionists during CT-guided interventions (CTGIs). To our knowledge, no data exist regarding the radiation dose to which the interventionist is exposed during these procedures.
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Feasibility of slice width reduction for spiral cranial computed tomography using iterative image reconstruction.
Eur J Radiol
PUBLISHED: 01-28-2014
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To prospectively compare image quality of cranial computed tomography (CCT) examinations with varying slice widths using traditional filtered back projection (FBP) versus sinogram-affirmed iterative image reconstruction (SAFIRE).
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Feasibility study of computed vs measured high b-value (1400 s/mm²) diffusion-weighted MR images of the prostate.
World J Radiol
PUBLISHED: 01-24-2014
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To evaluate the impact of computed b = 1400 s/mm(2) (C-b1400) vs measured b = 1400 s/mm(2) (M-b1400) diffusion-weighted images (DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence (sFOV).
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23Na-magnetic resonance imaging of the human lumbar vertebral discs: in vivo measurements at 3.0 T in healthy volunteers and patients with low back pain.
Spine J
PUBLISHED: 01-17-2014
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1H magnetic resonance imaging (MRI) of the spine can rule out common causes of low back pain (LBP), such as disc protrusions or nerve root compression; however, no significant causal relation exists between morphology and the extent of symptoms. Functional MRI techniques, such as 23Na, may provide additional information, allowing indirect assessment of vertebral glycosaminoglycan concentrations, decreases in which are associated with early degenerative changes.
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Assessment of acute intestinal graft versus host disease by abdominal magnetic resonance imaging at 3 Tesla.
Eur Radiol
PUBLISHED: 01-14-2014
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After allogeneic stem cell transplantation (SCT), a reliable diagnosis of acute graft versus host disease (aGvHD) is essential for an early and successful treatment. It is the aim of this analysis to assess intestinal aGvHD by magnetic resonance imaging (MRI).
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Objective and subjective image quality of liver parenchyma and hepatic metastases with virtual monoenergetic dual-source dual-energy CT reconstructions: an analysis in patients with gastrointestinal stromal tumor.
Acad Radiol
PUBLISHED: 01-07-2014
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To compare in dual-energy CT (DECT) conventionally reconstructed polyenergetic images (PEI) at 120 kVp to virtual monoenergetic images (MEI) at different kiloelectron volt (keV) levels for evaluation of liver and gastrointestinal stromal tumor (GIST) hepatic metastases with regard to objective (IQob) and subjective image quality (IQsub) assessed by two readers of varying experience. Image quality was correlated to patient size and compared between PEI and MEI.
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Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
PLoS ONE
PUBLISHED: 01-01-2014
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To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station.
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Zoomed EPI-DWI of the pancreas using two-dimensional spatially-selective radiofrequency excitation pulses.
PLoS ONE
PUBLISHED: 01-01-2014
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Implementation of DWI in the abdomen is challenging due to artifacts, particularly those arising from differences in tissue susceptibility. Two-dimensional, spatially-selective radiofrequency (RF) excitation pulses for single-shot echo-planar imaging (EPI) combined with a reduction in the FOV in the phase-encoding direction (i.e. zooming) leads to a decreased number of k-space acquisition lines, significantly shortening the EPI echo train and potentially susceptibility artifacts.
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Impact of Time-Resolved MRA on Diagnostic Accuracy in Patients With Symptomatic Peripheral Artery Disease of the Calf Station.
AJR Am J Roentgenol
PUBLISHED: 11-23-2013
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OBJECTIVE. The purpose of this article is to evaluate the added diagnostic accuracy of time-resolved MR angiography (MRA) of the calves compared with continuous-table-movement MRA in patients with symptomatic lower extremity peripheral artery disease (PAD) using digital subtraction angiography (DSA) correlation. MATERIALS AND METHODS. Eighty-four consecutive patients with symptomatic PAD underwent a low-dose 3-T MRA protocol, consisting of continuous-table-movement MRA, acquired from the diaphragm to the calves, and an additional time-resolved MRA of the calves; 0.1 mmol/kg body weight (bw) of contrast material was used (0.07 mmol/kg bw for continuous-table-movement MRA and 0.03 mmol/kg bw for time-resolved MRA). Two radiologists rated image quality on a 4-point scale and stenosis degree on a 3-point scale. An additional assessment determined the degree of venous contamination and whether time-resolved MRA improved diagnostic confidence. The accuracy of stenosis gradation with continuous-table-movement and time-resolved MRA was compared with that of DSA as a correlation. Overall diagnostic accuracy was calculated for continuous-table-movement and time-resolved MRA. RESULTS. Median image quality was rated as good for 578 vessel segments with continuous-table-movement MRA and as excellent for 565 vessel segments with time-resolved MRA. Interreader agreement was excellent (? = 0.80-0.84). Venous contamination interfered with diagnosis in more than 60% of continuous-table-movement MRA examinations. The degree of stenosis was assessed for 340 vessel segments. The diagnostic accuracies (continuous-table-movement MRA/time-resolved MRA) combined for the readers were obtained for the tibioperoneal trunk (84%/93%), anterior tibial (69%/87%), posterior tibial (85%/91%), and peroneal (67%/81%) arteries. The addition of time-resolved MRA improved diagnostic confidence in 69% of examinations. CONCLUSION. The addition of time-resolved MRA at the calf station improves diagnostic accuracy over continuous-table-movement MRA alone in symptomatic patients with PAD.
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UMMPerfusion: an open source software tool towards quantitative MRI perfusion analysis in clinical routine.
J Digit Imaging
PUBLISHED: 09-21-2013
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To develop a generic Open Source MRI perfusion analysis tool for quantitative parameter mapping to be used in a clinical workflow and methods for quality management of perfusion data. We implemented a classic, pixel-by-pixel deconvolution approach to quantify T1-weighted contrast-enhanced dynamic MR imaging (DCE-MRI) perfusion data as an OsiriX plug-in. It features parallel computing capabilities and an automated reporting scheme for quality management. Furthermore, by our implementation design, it could be easily extendable to other perfusion algorithms. Obtained results are saved as DICOM objects and directly added to the patient study. The plug-in was evaluated on ten MR perfusion data sets of the prostate and a calibration data set by comparing obtained parametric maps (plasma flow, volume of distribution, and mean transit time) to a widely used reference implementation in IDL. For all data, parametric maps could be calculated and the plug-in worked correctly and stable. On average, a deviation of 0.032?±?0.02 ml/100 ml/min for the plasma flow, 0.004?±?0.0007 ml/100 ml for the volume of distribution, and 0.037?±?0.03 s for the mean transit time between our implementation and a reference implementation was observed. By using computer hardware with eight CPU cores, calculation time could be reduced by a factor of 2.5. We developed successfully an Open Source OsiriX plug-in for T1-DCE-MRI perfusion analysis in a routine quality managed clinical environment. Using model-free deconvolution, it allows for perfusion analysis in various clinical applications. By our plug-in, information about measured physiological processes can be obtained and transferred into clinical practice.
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On-Call Service of Neurosurgeons in Germany: Organization, Use of Communication Services, and Personal Acceptance of Modern Technologies.
J Neurol Surg A Cent Eur Neurosurg
PUBLISHED: 08-31-2013
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Background A significant proportion of acute care neurosurgical patients present to hospital outside regular working hours. The objective of our study was to evaluate the structure of neurosurgical on-call services in Germany, the use of modern communication devices and teleradiology services, and the personal acceptance of modern technologies by neurosurgeons.Materials and Methods A nationwide survey of all 141 neurosurgical departments in Germany was performed. The questionnaire consisted of two parts: one for neurosurgical departments and one for individual neurosurgeons. The questionnaire, available online and mailed in paper form, included 21 questions about on-call service structure; the availability and use of communication devices, teleradiology services, and other information services; and neurosurgeons personal acceptance of modern technologies.Results The questionnaire return rate from departments was 63.1% (89/141), whereas 187 individual neurosurgeons responded. For 57.3% of departments, teleradiology services were available and were frequently used by 62.2% of neurosurgeons. A further 23.6% of departments described using smartphone screenshots of computed tomography (CT) images transmitted by multimedia messaging service (MMS), and 8.6% of images were described as sent by unencrypted email. Although 47.0% of neurosurgeons reported owning a smartphone, only 1.1% used their phone for on-call image communication.Conclusion Teleradiology services were observed to be widely used by on-call neurosurgeons in Germany. Nevertheless, a significant number of departments appear to use outdated techniques or techniques that leave patient data unprotected. On-call neurosurgeons in Germany report a willingness to adopt more modern approaches, utilizing readily available smartphones or tablet technology.
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Value of monoenergetic low-kV dual energy CT datasets for improved image quality of CT pulmonary angiography.
Eur J Radiol
PUBLISHED: 07-22-2013
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High vessel attenuation and high contrast-to-noise ratio (CNR) are prerequisites for high diagnostic confidence in CT pulmonary angiography (CTPA). This study evaluated the impact of calculated monoenergetic dual-energy (DE) CTPA datasets on vessel attenuation and CNR.
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Interscanner comparison of dynamic contrast-enhanced MRI in prostate cancer: 1.5 versus 3 T MRI.
Invest Radiol
PUBLISHED: 07-13-2013
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The aim of the study was the comparison of the diagnostic potential of dynamic contrast-enhanced magnetic resonance imaging to differentiate between prostate carcinoma and normal prostate tissue as well as prostatitis at 2 different field strengths: 1.5 versus 3 T.
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Comparison of Epicardial Fat Volume by Computed Tomography in Black Versus White Patients With Acute Chest Pain.
Am. J. Cardiol.
PUBLISHED: 07-06-2013
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Disparities in the risk of coronary artery disease (CAD) between races may be influenced by differences in the thoracic adipose tissue. We compared computed tomography (CT)-derived volumes of epicardial adipose tissue (EAT), mediastinal adipose tissue (MAT), and pericoronary fat thickness (PFT) and correlations with CAD between black and white patients. This institutional review board-approved Health Insurance Portability and Accountability Act-compliant study included 372 age- and gender-matched black versus white patients (186 black, 54 ± 11 years, 50% men; 186 white, 54 ± 11 years, 50% men) who underwent CT for chest pain evaluation. EAT, MAT, and PFT were measured. The amount of coronary calcium was quantified as calcium score. CAD was defined as ?50% coronary artery narrowing. EAT and MAT volumes were significantly lower in black than white patients (59 [twenty-fifth to seventy-fifth percentile 39 to 84] vs 97 [67 to 132] cm(3) and 44 [27 to 77] vs 87 [52 to 157] cm(3), for both p <0.001). Mean PFT in black patients was slightly lower than white patients (17.2 ± 3.2 vs 18.1 ± 3.4 mm, p <0.01). The relation between race and extent of adipose tissue remained significant after adjustment for cardiovascular risk factors. Significant correlations were observed between EAT and MAT volumes and calcium score in black and white patients (r = 0.19 to 0.26, p <0.01). For both races, the level of thoracic fat measurements was higher in present versus absent coronary calcification. A greater amount of thoracic fat was found with obstructive CAD only in white patients. In conclusion, CT-derived measurements of thoracic fat differ between symptomatic black and white patients, suggesting a differential relation between thoracic adipose tissue and CAD pathophysiology by race.
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In vivo sodium ((23)Na) imaging of the human kidneys at 7 T: Preliminary results.
Eur Radiol
PUBLISHED: 06-24-2013
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To evaluate the feasibility of in vivo (23)Na imaging of the corticomedullary (23)Na gradient and to measure (23)Na transverse relaxation times (T2*) in human kidneys.
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Clinical application of 3D VIBECAIPI-DIXON for non-enhanced imaging of the pancreas compared to a standard 2D fat-saturated FLASH.
Clin Imaging
PUBLISHED: 06-23-2013
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To compare a fast 3D VIBE sequence with Dixon fat saturation and CAIPIRINHA acceleration techniques (3D VIBECAIPI-DIXON) to a standard 2D FLASH sequence with spectral fat saturation and conventional GRAPPA acceleration technique (2D FlashGRAPPA-fs) for non-enhanced imaging of the pancreas.
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Contrast-enhanced 3-dimensional SPACE versus MP-RAGE for the detection of brain metastases: considerations with a 32-channel head coil.
Invest Radiol
PUBLISHED: 05-22-2013
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The aim of this study was to compare the detection of brain metastases at 3 T using a 32-channel head coil with 2 different 3-dimensional (3D) contrast-enhanced sequences, a T1-weighted fast spin-echo-based (SPACE; sampling perfection with application-optimized contrasts using different flip angle evolutions) sequence and a conventional magnetization-prepared rapid gradient-echo (MP-RAGE) sequence.
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Impact of field strength and RF excitation on abdominal diffusion-weighted magnetic resonance imaging.
World J Radiol
PUBLISHED: 04-30-2013
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To retrospectively and prospectively compare diffusion-weighted (DW) images in the abdomen in a 1.5T system and 3.0T systems with and without two-channel functionality for B1 shimming.
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Epicardial adipose tissue assessed by cardiac magnetic resonance imaging in patients with heart failure due to dilated cardiomyopathy.
Obesity (Silver Spring)
PUBLISHED: 04-18-2013
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We sought to investigate the association of the EAT with CMR parameters of ventricular remodelling and left ventricular (LV) dysfunction in patients with non-ischemic dilated cardiomyopathy (DCM).
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Detection of myocardial ischemia by automated, motion-corrected, color-encoded perfusion maps compared with visual analysis of adenosine stress cardiovascular magnetic resonance imaging at 3 T: a pilot study.
Invest Radiol
PUBLISHED: 04-09-2013
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The purpose of this study was to compare automated, motion-corrected, color-encoded (AMC) perfusion maps with qualitative visual analysis of adenosine stress cardiovascular magnetic resonance imaging for detection of flow-limiting stenoses.
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Repetitive MR measurements of lung volume in fetuses with congenital diaphragmatic hernia: individual development of pulmonary hypoplasia during pregnancy and calculation of weekly lung growth rates.
Eur Radiol
PUBLISHED: 04-08-2013
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To investigate individual changes in fetal lung volume (FLV) in fetuses with isolated congenital diaphragmatic hernia (CDH) and to calculate weekly growth rates of the FLV using serial MR examinations during pregnancy.
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Steady state vascular imaging with extracellular gadobutrol: evaluation of the additional diagnostic benefit in patients who have undergone a peripheral magnetic resonance angiography protocol.
J Cardiovasc Magn Reson
PUBLISHED: 04-06-2013
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To evaluate the feasibility and additional diagnostic benefit of a high-resolution steady state 3D-volume interpolated breath-hold exam (VIBE) sequence between a continuous table movement (CTM) MR angiography of the entire runoff vasculature and a time-resolved (TWIST) MRA of the calves.
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Dynamic volume perfusion CT in patients with lung cancer: baseline perfusion characteristics of different histological subtypes.
Eur J Radiol
PUBLISHED: 04-04-2013
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To evaluate dynamic volume perfusion CT (dVPCT) tumor baseline characteristics of three different subtypes of lung cancer in untreated patients.
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CAIPIRINHA-Dixon-TWIST (CDT)-volume-interpolated breath-hold examination (VIBE): a new technique for fast time-resolved dynamic 3-dimensional imaging of the abdomen with high spatial resolution.
Invest Radiol
PUBLISHED: 03-30-2013
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The purpose of this study was to assess the feasibility and image quality of a novel, highly accelerated T1-weighted sequence for time-resolved imaging of the abdomen during the first pass of contrast media transit using controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) under sampling, view-sharing techniques, and Dixon water-fat separation (CAIPRINHA-Dixon-time-resolved imaging with interleaved stochastic trajectories-volumetric interpolated breath-hold examination [CDT-VIBE]).
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Assessment of the renal corticomedullary (23)Na gradient using isotropic data sets.
Acad Radiol
PUBLISHED: 03-19-2013
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(23)Na magnetic resonance imaging is a promising technique for the noninvasive imaging of renal function. Past investigations of the renal corticomedullary [(23)Na] gradient have relied on imaging only in the coronal plane and on cumbersome calculations of [(23)Na], which require the use of external phantoms. The aim of this study is therefore two-fold: to use an isotropic three-dimensional data set to compare coronal measurements of renal [(23)Na] relative to measurements obtained in planes along the corticomedullary gradients and to investigate cerebrospinal fluid (CSF) (23)Na signal as an internal reference standard, obviating the need for time-intensive [(23)Na] calculations.
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Highly accelerated T1-weighted abdominal imaging using 2-dimensional controlled aliasing in parallel imaging results in higher acceleration: a comparison with generalized autocalibrating partially parallel acquisitions parallel imaging.
Invest Radiol
PUBLISHED: 03-07-2013
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The purpose of this study was to evaluate the feasibility and technical quality of an abdominal 3-dimensional interpolated breath-hold (volumetric interpolated breath-hold examination [VIBE]) magnetic resonance examination using the new parallel acquisition technique, controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA).
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Microwave Ablation of Osteoid Osteomas Using Dynamic MR Imaging for Early Treatment Assessment: Preliminary Experience.
J Vasc Interv Radiol
PUBLISHED: 03-03-2013
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To evaluate the efficacy of microwave ablation for osteoid osteomas by using dynamic contrast-enhanced magnetic resonance (MR) imaging in early treatment assessment.
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Dependence of image quality on acquisition time for the PET/CT Biograph mCT.
Z Med Phys
PUBLISHED: 03-01-2013
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The impact of acquisition time on reconstructed PET image quality is analyzed for different acquisition times (1, 2, 3 and 4min). Image quality was tested according to the National Electrical Manufacturers Association (NEMA) NU 2-2007, the evaluation for the signal to noise ratio (SNR) and the reconstructed activity ratio (RAR) for three algorithms, i.e. OSEM, TrueX and TOF applying different effective iteration numbers. The present work shows that the image quality of 3 and 4min acquisition time for spherical lesions of 10mm diameter are not significantly different between TrueX, TOF and OSEM. The 2min acquisition time should be used carefully for the TrueX and OSEM algorithms in small lesions, because the levels of background noise are high compared to 3 or 4min measurements. Also, the reconstructed activity ratio is underestimated to be approximately half of the expected value. For large lesions the three algorithms perform similarly for all acquisition durations, however, OSEM has the advantage of a more accurately reconstructed activity ratio compared to TrueX and TOF, which are more strongly influenced by noise.
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Nonenhanced ECG-gated quiescent-interval single shot MRA: Image quality and stenosis assessment at 3 tesla compared with contrast-enhanced MRA and digital subtraction angiography.
J Magn Reson Imaging
PUBLISHED: 02-27-2013
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To evaluate the diagnostic accuracy of a nonenhanced electrocardiograph-gated quiescent-interval single shot MR-angiography (QISS-MRA) at 3 Tesla with contrast-enhanced MRA (CE-MRA) and digital subtraction angiography (DSA) serving as reference standard.
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Optimization of keV-settings in abdominal and lower extremity dual-source dual-energy CT angiography determined with virtual monoenergetic imaging.
Eur J Radiol
PUBLISHED: 02-25-2013
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To compare objective image quality indices in dual-energy CT angiography (DE-CTA) studies of the abdomen and lower extremity using conventional polyenergetic images (PEIs) and virtual monoenergetic images (MEIs) at different kiloelectron volt (keV) levels.
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Quantitative analysis of coronary plaque composition by dual-source CT in patients with acute non-ST-elevation myocardial infarction compared to patients with stable coronary artery disease correlated with virtual histology intravascular ultrasound.
Acad Radiol
PUBLISHED: 02-01-2013
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To quantitatively assess coronary atherosclerotic plaque composition in patients with acute non-ST elevation myocardial infarction (NSTEMI) and patients with stable coronary artery disease (CAD) by coronary computed tomography angiography (cCTA) correlated with virtual histology intravascular ultrasound (VH-IVUS).
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Effect of reconstruction parameters in high-definition PET/CT on assessment of lymph node metastases in head and neck squamous cell carcinoma.
J Nucl Med Technol
PUBLISHED: 01-30-2013
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Therapy outcome and overall survival in patients with head and neck squamous cell carcinoma (HNSCC) is influenced by precise localization of the primary tumor and detection of lymph node metastasis involvement at the time of initial diagnosis. Only accurate preoperative staging can improve primary tumor response and avoid early locoregional recurrence with lymph node metastases. The purpose of this study was the optimization of reconstruction parameters in high-definition PET/CT for the improved diagnostic assessment of lymph node metastases.
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Quantitative in vivo (23)Na MR imaging of the healthy human kidney: determination of physiological ranges at 3.0T with comparison to DWI and BOLD.
MAGMA
PUBLISHED: 01-29-2013
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The purpose of this prospective study was to assess the normal physiologic ranges of the renal corticomedullary (23)Na-concentration ([(23)Na]) gradient at 3.0T in healthy volunteers. The corticomedullary [(23)Na] gradient was correlated with other functional MR imaging parameters-blood oxygenation level dependent (BOLD) and diffusion-weighted imaging (DWI)-and to individual and physiologic parameters-age, gender, estimated glomerular filtration rate (eGFR), body mass index (BMI), and blood serum sodium concentration ([(23)Na]serum).
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CT of urolithiasis: comparison of image quality and diagnostic confidence using filtered back projection and iterative reconstruction techniques.
Acad Radiol
PUBLISHED: 01-15-2013
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To compare the image quality and diagnostic confidence of low-dose computed tomography (CT) of urololithiasis using filtered back projection (FBP) and iterative reconstruction techniques (IRT).
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Correlation analysis of dual-energy CT iodine maps with quantitative pulmonary perfusion MRI.
World J Radiol
PUBLISHED: 01-14-2013
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To correlate dual-energy computed tomography (DECT) pulmonary angiography derived iodine maps with parameter maps of quantitative pulmonary perfusion magnetic resonance imaging (MRI).
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3T Renal (23)Na-MRI: effects of desmopressin in patients with central diabetes insipidus.
MAGMA
PUBLISHED: 01-13-2013
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PURPOSE: The purpose of this prospective study was to assess physiologic changes in the renal corticomedullary (23)Na-concentration ([(23)Na]) gradient with (23)Na-MRI at 3.0T in patients with central diabetes insipidus (CDI) before and after intranasal administration of 20 ?g desmopressin (DDAVP). METHODS AND MATERIALS: Four patients with CDI (all male, mean age 60.2 years) were included in this IRB-approved study. For (23)Na-imaging, a 3D density adapted, radial GRE-sequence (TE = 0.55 ms; TR = 120 ms; projections = 8,000; spatial resolution = 5 × 5 × 5 mm(3)) was used in combination with a dedicated (23)Na-coil and reference phantoms. The corticomedullary [(23)Na] gradient (in mmol/L/mm) was calculated pixel-by-pixel along a linear region-of-interest (ROI) spanning from the renal cortex in the direction of the medulla. Mean ± SDs of [(23)Na] were calculated for each patient as well as for the entire group. RESULTS: Mean [(23)Na] increased along the corticomedullary gradient from the cortex (pre-DDAVP 38.0 ± 6.3 mmol/L vs. post-DDAVP 30.7 ± 3.5 mmol/L) to the medulla (pre-DDAVP 71.6 ± 14.8 mmol/L vs. post-DDAVP 59.7 ± 10.8 mmol/L). The overall mean decrease of [(23)Na] after DDAVP administration was 17.1 ± 1.1 %. CONCLUSION: (23)Na-MRI with state-of-the-art techniques at 3T depicts the physiologic renal response to the administration of desmopressin in patients with central diabetes insipidus.
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Impact of iodine delivery rate with varying flow rates on image quality in dual-energy CT of patients with suspected pulmonary embolism.
Acad Radiol
PUBLISHED: 01-12-2013
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To prospectively compare four contrast material injection protocols for dual-energy computed tomography (CT) pulmonary angiography (DE-CTPA) in patients with suspected pulmonary embolism (PE).
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Diagnostic performance evaluation of a computer-aided simple triage system for coronary CT angiography in patients with intermediate risk for acute coronary syndrome.
Acad Radiol
PUBLISHED: 01-10-2013
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Given the significance of coronary artery disease as the most important socioeconomic health care problem in the Western World, the application of computer-aided simple triage (CAST) systems to this disease would be desirable.
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Is the assessment of the central skeleton sufficient for osseous staging in breast cancer patients? A retrospective approach using bone scans.
Skeletal Radiol.
PUBLISHED: 01-04-2013
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By analyzing bone scans we aimed to determine whether the assessment of the central skeleton is sufficient for osseous staging in breast cancer patients. This might be of interest for future staging modalities, especially positron emission tomography/computed tomography, usually sparing the peripheral extremities, as well as the skull.
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Value of Diffusion-Weighted MR Imaging for the Detection of Nephritis.
ScientificWorldJournal
PUBLISHED: 01-01-2013
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Purpose. To evaluate diffusion-weighted MR imaging (DWI-MRI) for the detection and assessment of infectious renal disease. Materials and Methods. Twenty-one patients with suspicious increased signal intensity of the kidneys on DWI sequences and corresponding ADC decrease were identified. Sixty patients without clinical signs of renal infection served as a control group. All patients were examined with the following sequences: EPI-DWI (0/400/800?s/mm(2)), T2w HASTE, and T1w VIBE after intravenous injection of Gd-chelate. Confirmation of renal infection was established on the basis of clinical criteria. T1w and T2w images were assessed and compared to DWI for the presence of altered signal, and the degree of the visibility of pathology was graded on an ordinal three-point scale. Results. In all 21 patients with positive DWI findings a renal infection could be confirmed. T2w imaging and contrast-enhanced T1w imaging displayed obvious pathologic signal in 3/21 (14%) and 11/19 (58%) patients and slightly pathologic signal in 17/21 (81%) and 7/19 (37%), respectively. The median visibility score of 2 for the DWI and the T1w images was significantly higher than the score of 1 for the T2w imaging, P = 0.0001 (DWI versus T2w) and P = 0.078 (T1w versus T2w). Conclusion. DWI of the kidneys seems to be highly sensitive for the detection of infections within the kidney.
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Comparison of Dynamic and Liver-Specific Gadoxetic Acid Contrast-Enhanced MRI versus Apparent Diffusion Coefficients.
PLoS ONE
PUBLISHED: 01-01-2013
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Hepatic lesions often present diagnostic connundrums with conventional MR techniques. Hepatobiliary phase contrast-enhanced imaging with gadoxetic acid can aid in the characterization of such lesions. However, quantitative measures describing late-phase enhancement must be assessed relative to their accuracy of hepatic lesion classification. PURPOSE: To compare quantitative parameters in gadoxetic acid contrast-enhanced dynamic and hepatobiliary phase imaging versus apparent diffusion coefficients in hepatic lesion characterization.
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Quantitative and qualitative (23)Na MR imaging of the human kidneys at 3 T: before and after a water load.
Radiology
PUBLISHED: 07-19-2011
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To qualitatively and quantitatively assess the corticomedullary sodium 23 ((23)Na) concentration in human kidneys before and after oral administration of a water load by using 3-T magnetic resonance (MR) imaging.
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Gadofosveset: parameter optimization for steady-state imaging of the thoracic and abdominal vasculature.
Invest Radiol
PUBLISHED: 06-29-2011
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Comparison of 3 optimized pulse sequences for thoracoabdominal contrast-enhanced magnetic-resonance angiography by signal-to-noise measurements and time-dependent T1 mapping in the steady state after injection of 0.03 mmol/kg BW gadofosveset.
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Combined large field-of-view MRA and time-resolved MRA of the lower extremities: impact of acquisition order on image quality.
Eur J Radiol
PUBLISHED: 05-27-2011
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Different approaches exist for hybrid MRA of the calf station. So far, the order of the acquisition of the focused calf MRA and the large field-of-view MRA has not been scientifically evaluated. Therefore the aim of this study was to evaluate if the quality of the combined large field-of-view MRA (CTM MR angiography) and time-resolved MRA with stochastic interleaved trajectories (TWIST MRA) depends on the order of acquisition of the two contrast-enhanced studies.
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Quantification of left and right ventricular function and myocardial mass: comparison of low-radiation dose 2nd generation dual-source CT and cardiac MRI.
Eur J Radiol
PUBLISHED: 05-14-2011
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To prospectively evaluate the accuracy of left and right ventricular function and myocardial mass measurements based on a dual-step, low radiation dose protocol with prospectively ECG-triggered 2nd generation dual-source CT (DSCT), using cardiac MRI (cMRI) as the reference standard.
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Radiation dose at coronary CT angiography: second-generation dual-source CT versus single-source 64-MDCT and first-generation dual-source CT.
AJR Am J Roentgenol
PUBLISHED: 04-23-2011
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The purpose of this study was to assess the radiation doses of different coronary CTA (CTA) protocols: second-generation dual-source 128-MDCT, first-generation dual-source 64-MDCT, and single-source 64-MDCT.
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Venous thromboembolism: additional diagnostic value and radiation dose of pelvic CT venography in patients with suspected pulmonary embolism.
Eur J Radiol
PUBLISHED: 04-16-2011
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To assess the additional diagnostic value of indirect CT venography (CTV) of the pelvis and upper thighs performed after pulmonary CT angiography (CTA) for the diagnosis of venous thromboembolism (VTE).
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Two non-invasive GFR-estimation methods in rat models of polycystic kidney disease: 3.0 Tesla dynamic contrast-enhanced MRI and optical imaging.
Nephrol. Dial. Transplant.
PUBLISHED: 03-28-2011
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The aim of this study was the assessment of kidney morphology and glomerular filtration rate (GFR) in rat models of polycystic kidney disease and a healthy control group of Sprague-Dawley rats (SD rats). The performance of two non-invasive GFR estimation methods-3.0 Tesla magnetic resonance imaging (MRI) and optical imaging were investigated. Data of GFR assessment was compared to surrogate markers of kidney function and renal histology.
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Comparison of the diagnostic accuracy of whole-body MRI and whole-body CT in stage III/IV malignant melanoma.
J Dtsch Dermatol Ges
PUBLISHED: 03-01-2011
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Malignant melanoma (MM) is dramatically increasing in light-skinned populations worldwide. Staging and regular follow-up examinations are essential. The purpose of this study was to compare the diagnostic accuracy of whole-body MRI with the standard diagnostic algorithm (whole-body CT and brain MRI) in patients with stage III/IV MM.
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Ferumoxtran-10 MR lymphography for target definition and follow-up in a patient undergoing image-guided, dose-escalated radiotherapy of lymph nodes upon PSA relapse.
Strahlenther Onkol
PUBLISHED: 02-21-2011
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Evaluation of the lymph node situation in patients with prostate cancer is essential for effective radiotherapy. Using magnet resonance imaging (MRI) of the lymph nodes with ferumoxtran-10 (MR lymphography), it is possible to detect lymph node metastasis. We present our initial experience with ferumoxtran-10 MR lymphography as the basis for image-guided, dose-escalated lymph node radiotherapy and for early follow-up after radiotherapy.
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Assessment of the kidneys: magnetic resonance angiography, perfusion and diffusion.
J Cardiovasc Magn Reson
PUBLISHED: 02-18-2011
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Renal magnetic resonance (MR) imaging has undergone major improvements in the past several years. This review focuses on the technical basics and clinical applications of MR angiography (MRA) with the goal of enabling readers to acquire high-resolution, high quality renal artery MRA. The current role of contrast agents and their safe use in patients with renal impairment is discussed. In addition, an overview of promising techniques on the horizon for renal MR is provided. The clinical value and specific applications of renal MR are critically discussed.
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Imaging of non-atherosclerotic aneurysmal disease.
Eur J Radiol
PUBLISHED: 02-16-2011
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Atherosclerotic aneurysms account for about 95% of all aneurysms. This overview concentrates on the 5% leftover, which however represents a heterogenic group of aneurysms with a wide range of different pathogenesis. Thus, therapy is not exclusively restricted to the exclusion of the aneurysm. In non-atherosclerotic aneurysmal disease various additional therapeutic strategies are included such as chemotherapy, anti-inflammatory therapy and embolisation procedures. Diagnosis, therapeutic decision making and even therapy itself to a growing extent depends on adequate (pretherapeutic) imaging and therefore radiologic expertise. This review describes the most common forms of non-atherosclerotic aneurysms and focuses on their pathogenesis, potential diagnostic approaches and therapy options.
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Cost-effectiveness of substituting dual-energy CT for SPECT in the assessment of myocardial perfusion for the workup of coronary artery disease.
Eur J Radiol
PUBLISHED: 01-28-2011
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We compared cost-effectiveness and potential lifetime benefits of using dual-energy computed tomography (DECT) for myocardial perfusion assessment instead of single photon emission computed tomography (SPECT) for the workup of coronary artery disease (CAD).
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Magnetic resonance angiography (MRA) of the calf station at 3.0 T: intraindividual comparison of non-enhanced ECG-gated flow-dependent MRA, continuous table movement MRA and time-resolved MRA.
Eur Radiol
PUBLISHED: 01-28-2011
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To compare 3D non-enhanced ECG-gated inflow-dependent MRA (NE-MRA) vs. continuous table movement (CTM) MR-angiography and time-resolved TWIST-MRA in the calf station at 3.0 T in a clinical patient collective.
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Noise reduction and image quality improvement of low dose and ultra low dose brain perfusion CT by HYPR-LR processing.
PLoS ONE
PUBLISHED: 01-19-2011
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To evaluate image quality and signal characteristics of brain perfusion CT (BPCT) obtained by low-dose (LD) and ultra-low-dose (ULD) protocols with and without post-processing by highly constrained back-projection (HYPR)-local reconstruction (LR) technique.
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Value of multiparametric prostate MRI of the peripheral zone.
Z Med Phys
PUBLISHED: 01-17-2011
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MRI of the prostate offers the possibility to localize and stage prostate cancer and may improve detection of disease. Currently, T2-weighted images and spectroscopy are the most commonly used MRI techniques. To assess the value of prostate MRI and its different modalities in the process of diagnosis, the currently available MRI techniques were compared.
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