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Find video protocols related to scientific articles indexed in Pubmed.
Anthropometric measures as screening test for carpal tunnel syndrome: ROC curves and accuracy.
Arthritis Care Res (Hoboken)
PUBLISHED: 09-03-2014
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Objective Some anthropometric measures were reported in association with carpal tunnel syndrome (CTS). Our aim was to detect optimal cut-offs of body, hand/wrist measures to correctly identify CTS patients using receiver-operating characteristic (ROC) curves. Methods We enrolled one CTS case for two controls regardless of age and gender. CTS diagnosis was made according to clinical findings and distal conduction delay of the median nerve. Anthropometric measures were: weight, height, waist and hip circumferences, wrist depth and width, third digit length, palm length and width. Obesity indicators and hand and wrist ratios were calculated. Area under the ROC curves (AUC), sensitivity, specificity, and likelihood ratios were calculated separately for gender. To assess the role of multiple anthropometric measures, we fitted multivariable logistic regression models including age, wrist ratio, shape index, body mass index, and waist-to-hip ratio. Results 1,117 patients were included (250 cases and 474 controls among females; 120 cases and 273 controls among males). Among females, all anthropometric measures presented low accuracy (AUC?0.64). Among males, hand ratio, shape index, and wrist-palm ratio showed moderate accuracy (AUC 0.75). The estimates from the multivariable models confirmed the well-known associations between the selected variables and the risk of CTS, but the use of multiple predictors did not dramatically improved the diagnostic performance observed for single anthropometric indexes. Conclusion The cut-offs of many anthropometric measures have limited value in clinical practice as a diagnostic tool for CTS. © 2014 American College of Rheumatology.
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0408?PubMed search strings for the study of putative environmental determinants of disease.
Occup Environ Med
PUBLISHED: 07-15-2014
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Several optimised search strategies have been developed in Medicine, and more recently in Occupational Medicine. Aim of this study is to identify efficient PubMed search strategies for the study of putative environmental determinants of a disease.
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Tobacco smoke and risk of childhood acute lymphoblastic leukemia: findings from the SETIL case-control study.
Cancer Causes Control
PUBLISHED: 03-20-2014
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Tobacco smoke could cause childhood acute lymphoblastic leukemia (ALL) through at least three pathways: (1) prenatal parental smoking; (2) fetal exposure through maternal smoking during pregnancy; and (3) childhood exposure to secondhand smoke (SHS). We tested these hypotheses in a large population-based case-control study (SETIL) primarily designed to evaluate the role of electromagnetic fields in childhood hematopoietic malignancies.
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Waist circumference and waist-to-hip ratio in carpal tunnel syndrome: a case-control study.
J. Neurol. Sci.
PUBLISHED: 01-05-2014
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The association between carpal tunnel syndrome (CTS) and high body mass index (BMI) and some hand measures is well known. No study has been specifically focused on waist circumference (WC) and waist-to-hip-ratio (WHR). The aim of this prospective case-control study is to evaluate the association between CTS and WC, WHR and other body and hand anthropometric measures.
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Tobacco Smoke and Risk of Childhood Acute Non-Lymphocytic Leukemia: Findings from the SETIL Study.
PLoS ONE
PUBLISHED: 01-01-2014
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Parental smoking and exposure of the mother or the child to environmental tobacco smoke (ETS) as risk factors for Acute non-Lymphocytic Leukemia (AnLL) were investigated.
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The MOBI-Kids Study Protocol: Challenges in Assessing Childhood and Adolescent Exposure to Electromagnetic Fields from Wireless Telecommunication Technologies and Possible Association with Brain Tumor Risk.
Front Public Health
PUBLISHED: 01-01-2014
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The rapid increase in mobile phone use in young people has generated concern about possible health effects of exposure to radiofrequency (RF) and extremely low frequency (ELF) electromagnetic fields (EMF). MOBI-Kids, a multinational case-control study, investigates the potential effects of childhood and adolescent exposure to EMF from mobile communications technologies on brain tumor risk in 14 countries. The study, which aims to include approximately 1,000 brain tumor cases aged 10-24?years and two individually matched controls for each case, follows a common protocol and builds upon the methodological experience of the INTERPHONE study. The design and conduct of a study on EMF exposure and brain tumor risk in young people in a large number of countries is complex and poses methodological challenges. This manuscript discusses the design of MOBI-Kids and describes the challenges and approaches chosen to address them, including: (1) the choice of controls operated for suspected appendicitis, to reduce potential selection bias related to low response rates among population controls; (2) investigating a young study population spanning a relatively wide age range; (3) conducting a large, multinational epidemiological study, while adhering to increasingly stricter ethics requirements; (4) investigating a rare and potentially fatal disease; and (5) assessing exposure to EMF from communication technologies. Our experience in thus far developing and implementing the study protocol indicates that MOBI-Kids is feasible and will generate results that will contribute to the understanding of potential brain tumor risks associated with use of mobile phones and other wireless communications technologies among young people.
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[Musculoskeletal disorders in farmers].
G Ital Med Lav Ergon
PUBLISHED: 12-06-2013
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Musculoskeletal disorders are a relevant issue among farmers. From the literature it emerges a convincing evidence for an association of arthritis of the hip and work in the agricultural sector, while there is a less evidence when studying knee osteoarthritis and farming. For what concerns cervicobrachial pain, current available epidemiological data are not sufficient to define farmers at risk. Moreover, there is uncertainty about the role of hand-arm vibration as a strong risk factor among farmers. Overall, the high occurrence of musculoskeletal disorders among farmers highligths the need for more specific studies in order to assess the various tasks performed by agricultural workers from which to derive appropriate prevention interventions.
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Musculoskeletal pain in Europe: the role of personal, occupational, and social risk factors.
Scand J Work Environ Health
PUBLISHED: 09-05-2013
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The prevalence of musculoskeletal pain in European countries varies considerably. We analyzed data from the fifth European Working Conditions Survey (EWCS) to explore the role of personal, occupational, and social risk factors in determining the national prevalence of musculoskeletal pain.
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PubMed search strings for the study of agricultural workers diseases.
Am. J. Ind. Med.
PUBLISHED: 08-05-2013
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Several optimized search strategies have been developed in Medicine, and more recently in Occupational Medicine. The aim of this study was to identify efficient PubMed search strategies to retrieve articles regarding putative occupational determinants of agricultural workers diseases.
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PubMed search strategies for the identification of etiologic associations between hypothalamic-pituitary disorders and other medical conditions.
Pituitary
PUBLISHED: 07-17-2013
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Biomedical literature has enormously grown in the last decades and become broadly available through online databases. Ad-hoc search methods, created on the basis of research field and goals, are required to enhance the quality of searching. Aim of this study was to formulate efficient, evidence-based PubMed search strategies to retrieve articles assessing etiologic associations between a condition of interest and hypothalamic-pituitary disorders (HPD). Based on expert knowledge, 17 MeSH (Medical Subjects Headings) and 79 free terms related to HPD were identified to search PubMed. Using random samples of abstracts retrieved by each term, we estimated the proportion of articles containing pertinent information and formulated two strings (one more specific, one more sensitive) for the detection of articles focusing on the etiology of HPD, that were then applied to retrieve articles identifying possible etiologic associations between HPD and three diseases (malaria, LHON and celiac disease) considered not associated to HPD, and define the number of abstracts needed to read (NNR) to find one potentially pertinent article. We propose two strings: one sensitive string derived from the combination of articles providing the largest literature coverage in the field and one specific including combined terms retrieving ?40% of potentially pertinent articles. NNR were 2.1 and 1.6 for malaria, 3.36 and 2.29 for celiac disease, 2.8 and 2.2 for LHON, respectively. For the first time, two reliable, readily applicable strings are proposed for the retrieval of medical literature assessing putative etiologic associations between HPD and other medical conditions of interest.
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Carcinoma of the pharynx and tonsils in an occupational cohort of asphalt workers.
Epidemiology
PUBLISHED: 06-01-2013
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We investigated a possible association between pharyngeal/tonsillar carcinoma and mixed carcinogen exposures in an asphalt roll company in Italy that used asbestos until 1979, when a new factory was built using a different production process.
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Risk of mesothelioma following external beam radiotherapy for prostate cancer: a cohort analysis of SEER database.
Cancer Causes Control
PUBLISHED: 05-08-2013
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To investigate the association between external beam radiotherapy (EBRT) for prostate cancer and mesothelioma using data from the US Surveillance, Epidemiology, and End Results (SEER) cancer registries.
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Asbestos: a hidden player behind the cholangiocarcinoma increase? Findings from a case-control analysis.
Cancer Causes Control
PUBLISHED: 02-04-2013
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We conducted a case-control analysis to explore the association between occupational exposure to asbestos and cholangiocarcinoma (CC).
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Incidence rates of surgically treated rhegmatogenous retinal detachment among manual workers, non-manual workers and housewives in Tuscany, Italy.
Int Arch Occup Environ Health
PUBLISHED: 01-09-2013
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Candidate risk factors for idiopathic rhegmatogenous retinal detachment (RRD) include heavy manual handling (requiring Valsalvas maneuver). We assessed incidence rates of surgically treated idiopathic RRD among manual workers, non-manual workers and housewives resident in Tuscany, Italy.
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Loads of housework? Biomechanical assessments of the upper limbs in women performing common household tasks.
Int Arch Occup Environ Health
PUBLISHED: 07-19-2011
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Housework is a form of regular manual work that is often performed by women. Little is known about the entity of biomechanical exposure to the upper limbs during typical housework tasks. This study aims to make an initial quantitative estimate of some such exposures.
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Workplace interventions for treatment of occupational asthma.
Cochrane Database Syst Rev
PUBLISHED: 05-13-2011
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The impact of workplace interventions on the outcome of occupational asthma is not well-understood.
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A case report of vibration-induced hand comorbidities in a postwoman.
BMC Musculoskelet Disord
PUBLISHED: 02-14-2011
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Prolonged exposure to hand-transmitted vibration is associated with an increased occurrence of symptoms and signs of disorders in the vascular, neurological and osteoarticular systems of the upper limbs. However, the available epidemiological evidence is derived from studies on high vibration levels caused by vibratory tools, whereas little is known about possible upper limb disorders caused by chronic exposure to low vibration levels emitted by fixed sources.
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"Is this case of a very rare disease work-related?" A review of reported cases of Pacinian neuroma.
Scand J Work Environ Health
PUBLISHED: 11-17-2010
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In response to a request for a medicolegal opinion from an orthopaedic technician with pacinian neuroma of the hand, we conducted a systematic review of reported cases designed to assess whether this rare disease could be considered to be work-related.
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[COMMUNITY: project proposal for a multicenter study on musculoskeletal comorbidity among nursing staff].
G Ital Med Lav Ergon
PUBLISHED: 11-11-2010
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While a high prevalence of musculoskeletal disorders (MSDs) has been registered among nurses, little is known on the prevalence of musculoskeletal comorbidities and their effect on the natural history of spinal diseases. Here we present a project called COMMUNITY (COMorbidities of MUsculoskeletal disorders among Nurse in ITalY) which is aimed at: 1) studying the prevalence of musculoskeletal comorbidities; 2) investigating the aetiology of MSDs; 3) investigating the aetiology of lumbar or cervical disk herniation; 4) evaluate the natural history of spinal disk herniation and its effect on work ability.
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Effectiveness of a Global Postural Reeducation program for persistent low back pain: a non-randomized controlled trial.
BMC Musculoskelet Disord
PUBLISHED: 06-14-2010
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The aim of this non-randomized controlled trial was to evaluate the effectiveness of a Global Postural Reeducation (GPR) program as compared to a Stabilization Exercise (SE) program in subjects with persistent low back pain (LBP) at short- and mid-term follow-up (ie. 3 and 6 months).
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Search strings for the study of putative occupational determinants of disease.
Occup Environ Med
PUBLISHED: 10-09-2009
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To identify efficient PubMed search strategies to retrieve articles regarding putative occupational determinants of conditions not generally considered to be work related.
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Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study.
BMC Public Health
PUBLISHED: 09-16-2009
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Carpal tunnel syndrome (CTS) is a socially and economically relevant disease caused by compression or entrapment of the median nerve within the carpal tunnel. This population-based case-control study aims to investigate occupational/non-occupational risk factors for surgically treated CTS.
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Effectiveness of an at-work exercise program in the prevention and management of neck and low back complaints in nursery school teachers.
Ind Health
PUBLISHED: 08-13-2009
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The aim of the study was to determine the effectiveness of an extension-oriented exercise program in the prevention and management of low back/neck pain in nursery school teachers. A Cluster Randomized Controlled Trial was utilized. Seventy-one nursery school teachers working in nine school buildings were randomly divided into two groups, with each school as a unit of randomization. All the teachers in both groups received an ergonomic brochure; teachers in the experimental group also received an extension-oriented exercise program, conducted by a physical therapist. Data were collected at baseline and at a two-month follow-up. The primary outcome measure recorded was the level of disability (Roland Morris Disability Questionnaire and Oswestry Disability Index), while secondary outcome measure included the evaluation of cervical and lumbar physical discomfort (Visual Analogue Scale). At follow-up, a significant improvement was registered in the experimental group as compared to the control group for all the outcomes evaluated. In conclusion an extension-oriented exercise program may be a useful strategy to prevent low back and neck complaints and to reduce consequent LBP functional disability among nursery school teachers.
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The background of mitochondrial DNA haplogroup J increases the sensitivity of Lebers hereditary optic neuropathy cells to 2,5-hexanedione toxicity.
PLoS ONE
PUBLISHED: 07-10-2009
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Lebers hereditary optic neuropathy (LHON) is a maternally inherited blinding disease due to mitochondrial DNA (mtDNA) point mutations in complex I subunit genes, whose incomplete penetrance has been attributed to both genetic and environmental factors. Indeed, the mtDNA background defined as haplogroup J is known to increase the penetrance of the 11778/ND4 and 14484/ND6 mutations. Recently it was also documented that the professional exposure to n-hexane might act as an exogenous trigger for LHON. Therefore, we here investigate the effect of the n-hexane neurotoxic metabolite 2,5-hexanedione (2,5-HD) on cell viability and mitochondrial function of different cell models (cybrids and fibroblasts) carrying the LHON mutations on different mtDNA haplogroups. The viability of control and LHON cybrids and fibroblasts, whose mtDNAs were completely sequenced, was assessed using the MTT assay. Mitochondrial ATP synthesis rate driven by complex I substrates was determined with the luciferine/luciferase method. Incubation with 2,5-HD caused the maximal loss of viability in control and LHON cells. The toxic effect of this compound was similar in control cells irrespective of the mtDNA background. On the contrary, sensitivity to 2,5-HD induced cell death was greatly increased in LHON cells carrying the 11778/ND4 or the 14484/ND6 mutation on haplogroup J, whereas the 11778/ND4 mutation in association with haplogroups U and H significantly improved cell survival. The 11778/ND4 mutation on haplogroup U was also more resistant to inhibition of complex I dependent ATP synthesis by 2,5-HD. In conclusion, this study shows that mtDNA haplogroups modulate the response of LHON cells to 2,5-HD. In particular, haplogroup J makes cells more sensitive to its toxic effect. This is the first evidence that an mtDNA background plays a role by interacting with an environmental factor and that 2,5-HD may be a risk element for visual loss in LHON. This proof of principle has broad implications for other neurodegenerative disorders such as Parkinsons disease.
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Effectiveness of an ergonomic intervention on work-related posture and low back pain in video display terminal operators: a 3 year cross-over trial.
Appl Ergon
PUBLISHED: 02-18-2009
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This study investigated the effectiveness of a workstation ergonomic intervention for work-related posture and low back pain (LBP) in Video Display Terminal (VDT) workers. 100 VDT workers were selected to receive the ergonomic intervention, whereas 100 were assigned to a control group. The two groups were then crossed-over after 30 months from baseline. Follow-ups were repeated at 5, 12, and 30 months from baseline and then at 6 months following crossover. Outcomes: Work-related posture and LBP point-prevalence using the Rapid Entire Body Assessment method and a Pain Drawing, respectively. The ergonomic intervention at the workstation improved work-related posture and was effective in reducing LBP point-prevalence both in the first study period and after crossover, and these effects persisted for at least 30 months. In conclusion, our findings contribute to the evidence that individualized ergonomic interventions may be able to improve work-related posture and reduce LBP for VDT workers.
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Factors influencing the diagnostic process of carpal tunnel syndrome.
Neurol. Sci.
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There are no studies regarding the course leading to carpal tunnel syndrome (CTS) diagnosis and factors influencing the diagnostic process. The study aim is to analyse CTS diagnostic path assessing whether the type of physician (general practitioners or specialist) may influence the manner and timing of diagnosis, and whether CTS severity at diagnosis may be predicted by factors related to Public Health Service and/or to patient. A medical history form was filled in by 375 consecutive patients with idiopathic CTS enrolled at an electromyography service. The patient answered a self-administered questionnaire on symptom severity and the neurophysiologist quantified clinical and electrophysiological CTS severity. The patients going directly to general practitioner were older and more blue collars, had minor education level, more symptom duration, more clinical and electrophysiological severity, more medical examination numbers, more time elapsing between first visit to a doctor and referral for EMG than those going to a specialist. But all variables are interrelated and when multivariate logistic regression analyses were performed, only patient age and some other few independent variables related to patient or health care but not to referring doctor could predict CTS severity at the diagnosis. Typology of the first doctor did not influence diagnostic path. The patients should reduce the time elapsing between CTS symptom onset and consulting doctor thus, permitting early treatments. Some corrective actions on diagnostic path may concern the public health service by reducing waiting lists to perform electrodiagnostic testing and giving greater information to population at risk.
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Occupational lifting tasks and retinal detachment in non-myopics and myopics: extended analysis of a case-control study.
Saf Health Work
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Lifting heavy weights involves the Valsalva manoeuvre, which leads to intraocular pressure spikes. We used data from a case-control study to further investigate the hypothesis that occupational lifting is a risk factor for retinal detachment.
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Validation of the ACGIH TLV for hand activity level in the OCTOPUS cohort: a two-year longitudinal study of carpal tunnel syndrome.
Scand J Work Environ Health
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This study aimed to evaluate the risk of musculoskeletal disorders to the hand-wrist system. The American Conference of Governmental Industrial Hygienists (ACGIH) proposed threshold limit values (TLV©) based on hand activity level (HAL) and normalized peak force (PF). We validated ACGIH TLV© in OCTOPUS, a large cohort study on carpal tunnel syndrome (CTS).
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Hidden effectiveness? Results of hand-searching Italian language journals for occupational health interventions.
Occup Environ Med
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To compare the yield of hand-searching with optimised electronic search strategies in retrieving occupational health (OH) intervention studies published in a language other than English.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.