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Find video protocols related to scientific articles indexed in Pubmed.
Guidelines for reporting case studies on extracorporeal treatments in poisonings: methodology.
Semin Dial
PUBLISHED: 05-29-2014
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A literature review performed by the EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup highlighted deficiencies in the existing literature, especially the reporting of case studies. Although general reporting guidelines exist for case studies, there are none in the specific field of extracorporeal treatments in toxicology. Our goal was to construct and propose a checklist that systematically outlines the minimum essential items to be reported in a case study of poisoned patients undergoing extracorporeal treatments. Through a modified two-round Delphi technique, panelists (mostly chosen from the EXTRIP workgroup) were asked to vote on the pertinence of a set of items to identify those considered minimally essential for reporting complete and accurate case reports. Furthermore, independent raters validated the clarity of each selected items between each round of voting. All case reports containing data on extracorporeal treatments in poisoning published in Medline in 2011 were reviewed during the external validation rounds. Twenty-one panelists (20 from the EXTRIP workgroup and an invited expert on pharmacology reporting guidelines) participated in the modified Delphi technique. This group included journal editors and experts in nephrology, clinical toxicology, critical care medicine, emergency medicine, and clinical pharmacology. Three independent raters participated in the validation rounds. Panelists voted on a total of 144 items in the first round and 137 items in the second round, with response rates of 96.3% and 98.3%, respectively. Twenty case reports were evaluated at each validation round and the independent raters' response rate was 99.6% and 98.8% per validation round. The final checklist consists of 114 items considered essential for case study reporting. This methodology of alternate voting and external validation rounds was useful in developing the first reporting guideline for case studies in the field of extracorporeal treatments in poisoning. We believe that this guideline will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports may provide early signals of effectiveness and/or harm, thereby improving healthcare decision-making.
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Extracorporeal treatment for tricyclic antidepressant poisoning: recommendations from the EXTRIP Workgroup.
Semin Dial
PUBLISHED: 04-09-2014
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The Extracorporeal Treatments In Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatments (ECTR) in poisoning. Here, the workgroup presents its results for tricyclic antidepressants (TCAs). After an extensive literature search, using a predefined methodology, the subgroup responsible for this poison reviewed the articles, extracted the data, summarized findings, and proposed structured voting statements following a predetermined format. A two-round modified Delphi method was chosen to reach a consensus on voting statements and RAND/UCLA Appropriateness Method to quantify disagreement. Blinded votes were compiled, returned, and discussed in person at a meeting. A second vote determined the final recommendations. Seventy-seven articles met inclusion criteria. Only case reports, case series, and one poor-quality observational study were identified yielding a very low quality of evidence for all recommendations. Data on 108 patients, including 12 fatalities, were abstracted. The workgroup concluded that TCAs are not dialyzable and made the following recommendation: ECTR is not recommended in severe TCA poisoning (1D). The workgroup considers that poisoned patients with TCAs are not likely to have a clinical benefit from extracorporeal removal and recommends it NOT to be used in TCA poisoning.
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Prevalence of depression morbidity among Brazilian adults: a systematic review and meta-analysis.
Rev Bras Psiquiatr
PUBLISHED: 03-26-2014
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To estimate the prevalence of depressive symptoms and major depressive disorder, as assessed in population-based cross-sectional studies of Brazilian adults.
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Statins for early stage chronic kidney disease: an overview of reviews.
Cardiovasc Hematol Disord Drug Targets
PUBLISHED: 03-23-2014
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To assess the efficacy of statin therapy on early stage chronic kidney disease through an overview of systematic reviews.
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[Economic evaluation of health technologies: checklist for critical analysis of published articles].
Rev. Panam. Salud Publica
PUBLISHED: 01-29-2014
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To propose a tool for critical analysis of economic evaluation studies based on a synthesis of checklists and guidelines available in the literature.
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Medication use in adults living in Brasilia, Brazil: a cross-sectional, population-based study.
Pharmacoepidemiol Drug Saf
PUBLISHED: 01-07-2014
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To assess the prevalence of medicine use in adults of Brasilia and to elucidate the associated factors.
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Problem-based learning in pharmaceutical education: a systematic review and meta-analysis.
ScientificWorldJournal
PUBLISHED: 01-01-2014
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To assess the effects of problem-based learning (PBL) on the learning achievements of pharmacy students.
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Prevalence of hypertension and associated factors in an indigenous community of central Brazil: a population-based study.
PLoS ONE
PUBLISHED: 01-01-2014
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The aim of the present study was to assess the prevalence of hypertension and cardiovascular risk factors among the native indigenous of Jaguapiru village in Dourados, Mato Grosso do Sul, Brazil.
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Pubertal timing in girls and depression: A systematic review.
J Affect Disord
PUBLISHED: 09-02-2013
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Because the incidence of depression increases after puberty, it is possible that pubertal timing in girls influences the onset of depression. Our objective was to assess the effect of early and late puberty in girls on the incidence of depression.
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Hypothermia for perinatal brain hypoxia-ischemia in different resource settings: a systematic review.
J. Trop. Pediatr.
PUBLISHED: 06-18-2013
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Objective: To assess the effect of hypothermia on mortality of neonates with hypoxic-ischemic encephalopathy in different economic resources settings. Methods: We searched for randomized controlled trials on MEDLINE, Embase and other databases. Duplicate reviewers selected the studies and extracted data. We calculated meta-analyses of the relative risks (RR) and 95% confidence intervals (95% CI), and used meta-regression to evaluate the gross domestic product per capita influence on hypothermia efficacy. Results: Sixteen studies were included (n = 1889); eight were conducted in lower income countries (n = 662). Hypothermia significantly reduced mortality (RR = 0.77; 95% CI: 0.65-0.92). Meta-regression revealed that hypothermia efficacy does not increase as the gross domestic product per capita rises. Conclusions: There is enough evidence to support hypothermia as the standard care for hypoxic-ischemic encephalopathy. Evidence from low-resource settings is limited, but hypothermia efficacy was not shown to be associated with better resources countries.
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Zinc supplementation for treating diarrhea in children: a systematic review and meta-analysis.
Rev. Panam. Salud Publica
PUBLISHED: 02-25-2013
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To update the available evidence about zinc use for treating diarrhea in children and to assess its effect on the malnourished population, a subgroup that has not been fully explored in previous analyses.
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Safety of benzathine penicillin for preventing congenital syphilis: a systematic review.
PLoS ONE
PUBLISHED: 01-09-2013
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To estimate the risk of serious adverse reactions to benzathine penicillin in pregnant women for preventing congenital syphilis.
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Impact of a poison control center on the length of hospital stay of poisoned patients: retrospective cohort.
Sao Paulo Med J
PUBLISHED: 03-26-2011
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Poison control centers play an essential role in caring for poisoned patients, albeit without secure funding for their activities. The aim here was to investigate differences in length of hospital stay among poisoned patients, between those who received remote assistance from a poison control center and those who did not.
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Olanzapine plus fluoxetine for bipolar disorder: a systematic review and meta-analysis.
J Affect Disord
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Olanzapine plus fluoxetine combination (OFC) is one of the current approaches for treating the depressive phase of bipolar disorder. Our objective was to synthesize the evidence on the efficacy of OFC therapy in bipolar depressed patients.
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Non-aspirin non-steroidal anti-inflammatory drugs for the primary chemoprevention of non-gastrointestinal cancer: summary of evidence.
Curr. Pharm. Des.
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There is evidence that aspirin is effective for the chemoprevention of colorectal cancer. Due to their similar pharmacodynamics, the use of other non-steroidal anti-inflammatory drugs (NSAIDs) has been suggested for other cancer sites. Although this possibility has been discussed in the literature, uncertainty remains about the actual effects of NSAIDs other than aspirin in nongastrointestinal cancer.
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Antioxidants for preventing preeclampsia: a systematic review.
ScientificWorldJournal
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To investigate the efficacy of antioxidants for preventing preeclampsia and other maternal and fetal complications among pregnant women with low, moderate, or high risk of preeclampsia.
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Economic evaluation of poison centers: a systematic review.
Int J Technol Assess Health Care
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The aim of this study was to summarize and assess economic evaluations of poison centers (PCs) from the perspectives of society, the payer, and the healthcare system.
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Dialyzer reuse and mortality risk in patients with end-stage renal disease: a systematic review.
Am. J. Nephrol.
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Robust evidence about dialyzer reuse effects on mortality is not available. Our aim was to summarize the evidence for the effectiveness of dialyzer reuse compared to single use in patients with end-stage renal disease.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.