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Find video protocols related to scientific articles indexed in Pubmed.
Validity of the Pediatric Running-Based Anaerobic Sprint Test to Determine Anaerobic Performance in Healthy Children.
Pediatr Exerc Sci
PUBLISHED: 11-12-2014
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To determine criterion validity of the pediatric running-based anaerobic sprint test (RAST) as a non-sophisticated field test for evaluating anaerobic performance in healthy children and adolescents.
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Factors associated with physical activity in children and adolescents with a physical disability: a systematic review.
Dev Med Child Neurol
PUBLISHED: 09-03-2014
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The aim of this review was to summarize the important factors associated with participation in physical activity in children and adolescents with physical disabilities.
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A Possible Alternative Exercise Test for Youth with Cystic Fibrosis: Steep Ramp Test.
Med Sci Sports Exerc
PUBLISHED: 07-11-2014
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The steep ramp test (SRT) can be used to provide an indication of exercise capacity when gas-exchange measurements are not possible. This study evaluated the clinical usefulness of the SRT in adolescents with cystic fibrosis (CF) and compared the physiological responses of the SRT with the standard cardiopulmonary exercise test (CPET).
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Prediction of mortality in adolescents with cystic fibrosis.
Med Sci Sports Exerc
PUBLISHED: 05-23-2014
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Lung function, nutritional status, and parameters of exercise capacity are known predictors of mortality in patients with cystic fibrosis (CF). The aim of the current study was to use these important parameters to develop a multivariate model to predict mortality in adolescent patients with CF.
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Effects of the Fitkids exercise therapy program on health-related fitness, walking capacity, and health-related quality of life.
Phys Ther
PUBLISHED: 05-01-2014
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Children with disabilities have an increased risk for reduced fitness and reduced health-related quality of life (HRQoL). Fitkids, a nationwide exercise therapy program in the Netherlands, was developed to improve fitness and HRQoL in children with disabilities.
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Factors influencing childhood cancer patients to participate in a combined physical and psychosocial intervention program: Quality of Life in Motion.
Psychooncology
PUBLISHED: 03-14-2014
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For a multi-center randomized trial investigating the effects of a 12-week physical and psychosocial intervention program for children with cancer, we invited 174 patients (8-18 years old) on treatment or within 1 year after treatment; about 40% participated. Reasons for non-participation were investigated.
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Exercise training programs to improve hand rim wheelchair propulsion capacity: a systematic review.
Clin Rehabil
PUBLISHED: 03-10-2014
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An adequate wheelchair propulsion capacity is required to perform daily life activities. Exercise training may be effective to gain or improve wheelchair propulsion capacity. This review investigates whether different types of exercise training programs are effective in improving wheelchair propulsion capacity.
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Comparing four non-invasive methods to determine the ventilatory anaerobic threshold during cardiopulmonary exercise testing in children with congenital heart or lung disease.
Clin Physiol Funct Imaging
PUBLISHED: 02-19-2014
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The ventilatory anaerobic threshold (VAT) is an important method to assess the aerobic fitness in patients with cardiopulmonary disease. Several methods exist to determine the VAT; however, there is no consensus which of these methods is the most accurate.
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Exercise capacity in children after total cavopulmonary connection: lateral tunnel versus extracardiac conduit technique.
J. Thorac. Cardiovasc. Surg.
PUBLISHED: 01-15-2014
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In patients with univentricular heart disease, the total cavopulmonary connection (TCPC) is the preferred treatment. TCPC can be performed using the intra-atrial lateral tunnel (ILT) or extracardiac conduit (ECC) technique. The purpose of the present study was to evaluate exercise capacity in contemporary TCPC patients and compare the results between the 2 techniques.
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Measurement of physical activity in patients with cystic fibrosis: a systematic review.
Expert Rev Respir Med
PUBLISHED: 11-15-2013
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Physical activity (PA) improves exercise capacity, slower decline in lung function and improve quality of life in patients with cystic fibrosis (CF). Despite the importance of PA, it is important to assess the amount of PA. The objective of this literature review was to evaluate the validity and usability of instruments that are used to measure PA in patients with CF. GoogleScholar, ScienceDirect, The Cochrane Library and PUBMED database were searched. All studies that included instruments to measure PA of patients with CF, published from 2000 till June 2012 were reviewed. Eight studies were included in this systematic review. At this moment, there is not sufficient evidence to support incorporation of specific tools to facilitate the PA assessment into clinical practice. Pedometers may offer an inexpensive method of obtaining a measurement of PA, and there is some evidence for supporting its use in CF.
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Reduced fat oxidation rates during submaximal exercise in adolescents with Crohns disease.
Inflamm. Bowel Dis.
PUBLISHED: 10-10-2013
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Children with Crohns disease (CD) suffer from malnutrition. Understanding substrate utilization during exercise may help patients with CD sustain a healthy active lifestyle without compromising nutrition. The aim of this study was to determine whether substrate utilization and bioavailability during exercise are altered in children with CD compared with controls.
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Effects of exercise on immune function in patients with cancer: a systematic review.
Exerc Immunol Rev
PUBLISHED: 08-28-2013
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The role of exercise therapy in the rehabilitation of cancer patients and survivors is becoming increasingly important as it is thought to modulate immunity and inflammation. More knowledge about the effects of exercise on immune function in these patients is needed. Our aim is to systematically review changes in immune parameters after acute and chronic exercise in cancer patients.
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Estimating peak oxygen uptake in adolescents with cystic fibrosis.
Arch. Dis. Child.
PUBLISHED: 07-26-2013
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To predict peak oxygen uptake (VO2peak) from the peak work rate (Wpeak) obtained during a cycle ergometry test using the Godfrey protocol in adolescents with cystic fibrosis (CF), and assess the accuracy of the model for prognostication clustering.
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Low aerobic capacity and physical activity not associated with fatigue in patients with rheumatoid arthritis: a cross-sectional study.
J Rehabil Med
PUBLISHED: 07-20-2013
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To explore whether low aerobic capacity and physical activity are associated with fatigue, when controlling for age, gender, pain and depressive symptoms in persons with rheumatoid arthritis.
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The steep ramp test in healthy children and adolescents: reliability and validity.
Med Sci Sports Exerc
PUBLISHED: 06-26-2013
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This study aimed to examine the reliability and validity of the steep ramp test (SRT), a feasible, maximal exercise test on a cycle ergometer that does not require the use of respiratory gas analysis, in healthy children and adolescents.
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Fitkids exercise therapy program in the Netherlands.
Pediatr Phys Ther
PUBLISHED: 06-06-2013
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To describe the demographics, medical diagnoses, and initial aerobic fitness levels of children participating in Fitkids: an exercise therapy program for children with chronic conditions or disabilities in the Netherlands.
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The Steep Ramp Test in Dutch white children and adolescents: age- and sex-related normative values.
Phys Ther
PUBLISHED: 05-30-2013
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The Steep Ramp Test (SRT), a feasible, reliable, and valid exercise test on a cycle ergometer, may be more appealing for use in children in daily clinical practice than the traditional cardiopulmonary exercise test because of its short duration, its resemblance to childrens daily activity patterns, and the fact that it does not require respiratory gas analysis.
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Reliability and validity of short-term performance tests for wheelchair-using children and adolescents with cerebral palsy.
Dev Med Child Neurol
PUBLISHED: 05-22-2013
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To investigate the test-retest reproducibility of the Muscle Power Sprint Test (MPST), the 10 × 5-m sprint test, and the arm-cranking Wingate Anaerobic Test (WAnT) in children and adolescents with cerebral palsy (CP). A secondary objective was to assess the construct validity of the MPST.
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Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk.
BMC Cancer
PUBLISHED: 05-02-2013
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Physical inactivity and overweight are two known risk factors for postmenopausal breast cancer. Former exercise intervention studies showed that physical activity influences sex hormone levels, known to be related to postmenopausal breast cancer, mainly when concordant loss of body weight was achieved. The question remains whether there is an additional beneficial effect of physical activity when weight loss is reached.The aim of this study is to investigate the effect attributable to exercise on postmenopausal breast cancer risk biomarkers, when equivalent weight loss is achieved compared to diet induced weight loss.
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Physical exercise training interventions for children and young adults during and after treatment for childhood cancer.
Cochrane Database Syst Rev
PUBLISHED: 05-02-2013
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A decreased physical fitness and impaired social functioning has been reported in patients and survivors of childhood cancer. This is influenced by the negative effects of disease and treatment of childhood cancer and by behavioural and social elements. Exercise training for adults during or after cancer therapy has frequently been reported to improve physical fitness and social functioning. More recently, literature on this subject became available for children and young adults with cancer, both during and after treatment.
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Reproducibility and validity of the 10-meter shuttle ride test in wheelchair-using children and adolescents with cerebral palsy.
Phys Ther
PUBLISHED: 04-11-2013
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For children with cerebral palsy (CP) who are able to walk or run, the 10-m shuttle run test is currently the test of choice to assess cardiorespiratory fitness. This test, however, has not yet been examined in wheelchair-using youth with CP.
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Reduced fat oxidation rates during submaximal exercise in boys with cystic fibrosis.
J. Cyst. Fibros.
PUBLISHED: 01-31-2013
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Exercise is a viable form of therapy for children with cystic fibrosis (CF). Understanding the energy sources used during exercise would aid CF patients in obtaining proper nutrition in order to sustain an active lifestyle.
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Validity of the muscle power sprint test in ambulatory youth with cerebral palsy.
Pediatr Phys Ther
PUBLISHED: 01-05-2013
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To validate the Muscle Power Sprint Test (MPST) against the Wingate Anaerobic cycling Test (WAnT) in a group of youth with cerebral palsy (CP).
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Safety and efficacy of exercise training in patients with an idiopathic inflammatory myopathy--a systematic review.
Rheumatology (Oxford)
PUBLISHED: 09-02-2011
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Idiopathic inflammatory myopathies (IIMs) are a group of rare heterogeneous autoimmune skeletal muscle disorders characterized by muscle weakness, excessive muscle fatigue and diminished aerobic fitness. Exercise training could be one way to prevent or delay the negative effects of the disease and the impairments seen in patients with an IIM. The objective was to examine whether exercise training is safe and effective in patients with an IIM.
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Inflammatory and growth factor response to continuous and intermittent exercise in youth with cystic fibrosis.
J. Cyst. Fibros.
PUBLISHED: 06-28-2011
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Children with cystic fibrosis (CF) tend to suffer from chronic systemic inflammation and may have impaired growth associated with muscle catabolism. Therefore, investigating which type of exercise can elicit an anabolic response with minimal inflammation is of clinical value.
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The 220-age equation does not predict maximum heart rate in children and adolescents.
Dev Med Child Neurol
PUBLISHED: 05-13-2011
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Our primary purpose was to provide maximum heart rate (HR(max) ) values for ambulatory children with cerebral palsy (CP). The secondary purpose was to determine the effects of age, sex, ambulatory ability, height, and weight on HR(max) . In 362 ambulatory children and adolescents with CP (213 males and 149 females; age range 6-19y; 195 spastic unilateral, 162 spastic bilateral, and five ataxic CP), HR(max) was measured during a 10-m (Gross Motor Function Classification System [GMFCS] levels I and II) or 7.5 m (GMFCS level III) shuttle run test. The mean HR(max) was 194 (SD 9.9) beats per minute (bpm), with a 95% prediction interval between 174 and 214 bpm. No associations were found in HR(max) related to age, sex, ambulatory ability, height, and weight. Since the HR(max) did not vary with age, equations such as 220-age are not appropriate. When direct evaluation of HR(max) with exercise testing is not feasible, we suggest the mean value of 194 bpm be considered as an estimate of HR(max) at the individual level.
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Carbohydrate intake reduces fat oxidation during exercise in obese boys.
Eur. J. Appl. Physiol.
PUBLISHED: 03-21-2011
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The recent surge in childhood obesity has renewed interest in studying exercise as a therapeutic means of metabolizing fat. However, carbohydrate (CHO) intake attenuates whole body fat oxidation during exercise in healthy children and may suppress fat metabolism in obese youth. To determine the impact of CHO intake on substrate utilization during submaximal exercise in obese boys, seven obese boys (mean age: 11.4 ± 1.0 year; % body fat: 35.8 ± 3.9%) performed 60 min of exercise at an intensity that approximated maximal fat oxidation. A CHO drink (CARB) or a placebo drink (CONT) was consumed in a double-blinded, counterbalanced manner. Rates of total fat, total CHO, and exogenous CHO (CHO(exo)) oxidation were calculated for the last 20 min of exercise. During CONT, fat oxidation rate was 3.9 ± 2.4 mg × kg fat-free mass (FFM)(-1 )× min(-1), representing 43.1 ± 22.9% of total energy expenditure (EE). During CARB, fat oxidation was lowered (p = 0.02) to 1.7 ± 0.6 mg × kg FFM(-1 )× min(-1), contributing to 19.8 ± 4.9% EE. Total CHO oxidation rate was 17.2 ± 3.1 mg × kg FFM(-1 )× min(-1) and 13.2 ± 6.1 mg × kg FFM(-1) × min(-1) during CARB and CONT, respectively (p = 0.06). In CARB, CHO(exo) oxidation contributed to 23.3 ± 4.2% of total EE. CHO intake markedly suppresses fat oxidation during exercise in obese boys.
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Randomized controlled study of home-based treadmill training for ambulatory children with spina bifida.
Neurorehabil Neural Repair
PUBLISHED: 03-17-2011
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Many ambulatory children with spina bifida (SB) decline in their walking despite stable or even improved motor function.
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Identification of a core set of exercise tests for children and adolescents with cerebral palsy: a Delphi survey of researchers and clinicians.
Dev Med Child Neurol
PUBLISHED: 02-11-2011
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Evidence-based recommendations regarding which exercise tests to use in children and adolescents with cerebral palsy (CP) are lacking. This makes it very difficult for therapists and researchers to choose the appropriate exercise-related outcome measures for this group. This study aimed to identify a core set of exercise tests for children and adolescents with CP.
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Reliability of a shuttle run test for children with cerebral palsy who are classified at Gross Motor Function Classification System level III.
Dev Med Child Neurol
PUBLISHED: 02-11-2011
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For children and adolescents with cerebral palsy (CP) classified as Gross Motor Function Classification System (GMFCS) level III there is no running-based field test available to assess their cardiorespiratory fitness. The current study investigated whether a shuttle run test can be reliably (test-retest) performed in a group of children with spastic diplegia (eight male, five female) classified as GMFCS level III. Thirteen children (mean age 12 y, SD 3 y) had to walk/run in squares of 7.5m delimited by cones. The auditory signals from the GMFCS II compact disc (as used in a previous reliability and validation study) were used during the test, resulting in a starting speed of 1.5 km/hour with a graded increase in speed of 0.19 km/hour per minute (shuttle). Intraclass correlation coefficients (two-way mixed) for achieved shuttles were 0.98. The standard error of measurement was 0.48 levels and the smallest detectable change was 1.32 shuttles. The results are the first indication that the shuttle run test protocol could be reliably performed in this population.
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Supramaximal verification of peak oxygen uptake in adolescents with cystic fibrosis.
Pediatr Phys Ther
PUBLISHED: 02-10-2011
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To study whether peak oxygen uptake ((Equation is included in full-text article VO??peak), attained in traditional cardiopulmonary exercise testing (CPET) in adolescents with cystic fibrosis (CF), could be verified by a supramaximal exercise test.
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The Utrecht approach to exercise in chronic childhood conditions: the decade in review.
Pediatr Phys Ther
PUBLISHED: 02-10-2011
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To summarize and discuss current evidence and understanding of clinical pediatric exercise physiology focusing on the work the research group at Utrecht and others have performed in the last decade in a variety of chronic childhood conditions as a continuation of the legacy of Dr Bar-Or.
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Reproducibility of maximal and submaximal exercise testing in "normal ambulatory" and "community ambulatory" children and adolescents with spina bifida: which is best for the evaluation and application of exercise training?
Phys Ther
PUBLISHED: 01-06-2011
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With emerging interest in exercise and lifestyle interventions for children and adolescents with spina bifida, there is a need for appropriate measurements in exercise testing.
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Design of the Quality of Life in Motion (QLIM) study: a randomized controlled trial to evaluate the effectiveness and cost-effectiveness of a combined physical exercise and psychosocial training program to improve physical fitness in children with cancer.
BMC Cancer
PUBLISHED: 10-18-2010
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Childhood cancer and its treatment have considerable impact on a childs physical and mental wellbeing. Especially long-term administration of chemotherapy and/or radiotherapy impairs physical fitness both during and after therapy, when children often present with muscle weakness and/or low cardiorespiratory fitness. Physical exercise can improve these two elements of physical fitness, but the positive effects of physical exercise might be further increased when a childs wellbeing is simultaneously enhanced by psychosocial training. Feeling better may increase the willingness and motivation to engage in sports activities. Therefore, this multi-centre study evaluates the short and long-term changes in physical fitness of a child with a childhood malignancy, using a combined physical exercise and psychosocial intervention program, implemented during or shortly after treatment. Also examined is whether positive effects on physical fitness reduce inactivity-related adverse health problems, improve quality of life, and are cost-effective.
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Oxygen uptake efficiency slope in healthy children.
Pediatr Exerc Sci
PUBLISHED: 09-04-2010
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The objective of this study was to investigate the characteristics of the submaximal Oxygen Uptake Efficiency Slope (OUES) in a healthy pediatric population. Bicycle ergometry exercise tests with gas-analyses were performed in 46 healthy children aged 7-17 years. Maximal OUES, submaximal OUES, VO(2)peak, V(E)peak, and ventilatory threshold (VT) were determined. The submaximal OUES correlated highly with VO(2)peak, V(E)peak, and VT. Strong correlations were found with basic anthropometric variables. The submaximal OUES could provide an objective, independent measure of cardiorespiratory function in children, reflecting efficiency of ventilation. We recommend expressing OUES values relative to Body Surface Area (BSA) or Fat Free Mass (FFM).
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Exercise capacity in pediatric patients with inflammatory bowel disease.
J. Pediatr.
PUBLISHED: 08-31-2010
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To examine exercise capacity in youth with Crohns disease (CD) and ulcerative colitis (UC).
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The oxygen uptake efficiency slope: what do we know?
J Cardiopulm Rehabil Prev
PUBLISHED: 08-21-2010
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To summarize what is currently known about the oxygen uptake efficiency slope (OUES) as an objective and independent submaximal measure of cardiorespiratory fitness in health and disease.
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Effects of a high-intensity task-oriented training on gait performance early after stroke: a pilot study.
Clin Rehabil
PUBLISHED: 08-18-2010
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To investigate the feasibility and the effects on gait of a high intensity task-oriented training, incorporating a high cardiovascular workload and large number of repetitions, in patients with subacute stroke, when compared to a low intensity physiotherapy-programme.
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Reference values for anaerobic performance and agility in ambulatory children and adolescents with cerebral palsy.
Dev Med Child Neurol
PUBLISHED: 07-28-2010
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the aim of this study was to provide reference values of anaerobic performance and agility in a group of children and adolescents with spastic cerebral palsy (CP).
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Can peak work rate predict peak oxygen uptake in children with juvenile idiopathic arthritis?
Arthritis Care Res (Hoboken)
PUBLISHED: 07-01-2010
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To examine whether peak work rate (W(peak)) can predict peak oxygen uptake (VO(2peak)) in children with juvenile idiopathic arthritis (JIA).
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Aerobic capacity in children and adolescents with cerebral palsy.
Res Dev Disabil
PUBLISHED: 06-23-2010
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This study described the aerobic capacity [VO(2peak) (ml/kg/min)] in contemporary children and adolescents with cerebral palsy (CP) using a maximal exercise test protocol. Twenty-four children and adolescents with CP classified at Gross Motor Functional Classification Scale (GMFCS) level I or level II and 336 typically developing children were included. All children performed a progressive exercise test on a treadmill with respiratory gas-exchange analysis. The results are compared with normative values for age and gender-matched controls. Aerobic capacity of children and adolescents with CP, who are classified at GMFCS level I or II was significantly lower than that of typically developing controls. Especially in girls with CP, the aerobic capacity deteriorated with age. The aerobic capacity of contemporary children and adolescents with CP, who are classified at GMFCS level I or II is significantly lower than that of typically developing controls.
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Reference values for aerobic fitness in children, adolescents, and young adults who have cerebral palsy and are ambulatory.
Phys Ther
PUBLISHED: 06-17-2010
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Very few objective data exist regarding aerobic performance in young people with cerebral palsy (CP). The characterization of aerobic fitness could provide baseline and outcome measures for the rehabilitation of young people with CP.
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Review of prediction models to estimate activity-related energy expenditure in children and adolescents.
Int J Pediatr
PUBLISHED: 05-02-2010
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Purpose. To critically review the validity of accelerometry-based prediction models to estimate activity energy expenditure (AEE) in children and adolescents. Methods. The CINAHL, EMBASE, PsycINFO, and PubMed/MEDLINE databases were searched. Inclusion criteria were development or validation of an accelerometer-based prediction model for the estimation of AEE in healthy children or adolescents (6-18 years), criterion measure: indirect calorimetry, or doubly labelled water, and language: Dutch, English or German. Results. Nine studies were included. Median methodological quality was 5.5 +/- 2.0 IR (out of a maximum 10 points). Prediction models combining heart rate and counts explained 86-91% of the variance in measured AEE. A prediction model based on a triaxial accelerometer explained 90%. Models derived during free-living explained up to 45%. Conclusions. Accelerometry-based prediction models may provide an accurate estimate of AEE in children on a group level. Best results are retrieved when the model combines accelerometer counts with heart rate or when a triaxial accelerometer is used. Future development of AEE prediction models applicable to free-living scenarios is needed.
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Exercise stress testing in children with metabolic or neuromuscular disorders.
Int J Pediatr
PUBLISHED: 01-07-2010
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The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.
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The effects of acute and chronic exercise on inflammatory markers in children and adults with a chronic inflammatory disease: a systematic review.
Exerc Immunol Rev
PUBLISHED: 12-05-2009
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Chronic inflammatory diseases strike millions of people all over the world, and exercise is often prescribed for these patients to improve overall fitness and quality of life. In healthy individuals, acute and chronic exercise is known to alter inflammatory markers; however, less is known about these effects in patients with a chronic inflammatory disease.
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Exercise testing of pre-school children using the Bruce treadmill protocol: new reference values.
Eur. J. Appl. Physiol.
PUBLISHED: 09-28-2009
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The Bruce treadmill protocol is an often-used exercise test for children and adults. Few and mainly old normative data are available for young children. In this cross-sectional observational study we determined new reference values for the original Bruce protocol in children aged 4 and 5 years. Furthermore, we compared the original protocol with the so-called half Bruce protocol. In the Netherlands this half-Bruce protocol is often used for young children because of the rather large increments in workload in the original protocol. Seventy-eight healthy Dutch children participated. The maximal endurance time was the criterion of exercise capacity. The new reference values for the original Bruce protocol are presented as reference centiles. The mean (SD) endurance time using the original protocol was 10.2 (SD 1.5) min.; this was 9.4 (1.3) min. for the half-Bruce protocol. The mean difference was 50 seconds (95% CI: 29-71 s, P < 0.001). So, for children aged 4 and 5 years the endurance times obtained with the original and half-Bruce protocol are different and should not be considered interchangeable. Our new reference values can be used as reference values for the original Bruce protocol.
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Risk and prognostic factors for non-specific musculoskeletal pain: a synthesis of evidence from systematic reviews classified into ICF dimensions.
Pain
PUBLISHED: 08-17-2009
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A wide variety of risk factors for the occurrence and prognostic factors for persistence of non-specific musculoskeletal pain (MSP) are mentioned in the literature. A systematic review of all these factors is not available. Thus a systematic review was conducted to evaluate MSP risk factors and prognostic factors, classified according to the dimensions of the International Classification of Functioning, Disability and Health. Candidate systematic reviews were identified in electronic medical journal databases, including the articles published between January 2000 and January 2008 that employed longitudinal cohort designs. The GRADE Working Groups criteria for assessing the overall level of evidence were used to evaluate the reviews. Nine systematic reviews were included, addressing a total of 67 factors. High evidence supported increased mobility of the lumbar spine and poor job satisfaction as risk factors for low back pain. There was also high evidence for intense pain during the onset of shoulder and neck pain and being middle aged as risk factors for shoulder pain. High evidence was also found for several factors that were not prognostic factors. For whiplash-associated disorders these factors were older age, being female, having angular deformity of the neck, and having an acute psychological response. Similarly, for persistence of low back pain, high evidence was found for having fear-avoidance beliefs and meagre social support at work. For low back pain, high evidence was found for meagre social support and poor job content at work as not being risk factors.
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Exercise training in pediatric patients with end-stage renal disease.
Pediatr. Nephrol.
PUBLISHED: 06-19-2009
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The objective of this study was to determine the feasibility and efficacy of an exercise training program to improve exercise capacity and fatigue level in pediatric patients with end-stage renal disease (ESRD). Twenty children on dialysis intended to perform a 12-week graded community-based exercise program. Exercise capacity and fatigue level were studied; muscle force and health-related quality of life were secondary outcomes. All outcomes were measured at baseline (T = 0) and after intervention (T = 1). Fourteen of the 20 patients (70%) either did not start the program or did not complete the program. Of these patients, seven did not complete or even start the exercise program because of a combination of lack of time and motivational problems. Six patients were not able to continue the program or were unable to do the follow-up measurements because of medical problems. Exercise capacity and muscle strength was higher after the exercise program in the children who completed the training. In conclusion, exercise training is difficult to perform in children with ESRD and is not always feasible in real-life situations for many children with ESRD.
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Muscle strength, aerobic capacity and physical activity in independent ambulating children with lumbosacral spina bifida.
Disabil Rehabil
PUBLISHED: 06-03-2009
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This cross-sectional study investigates deficits and associations in muscle strength, 6-minute walking distance (6MWD), aerobic capacity (VO(2peak)), and physical activity (PA) in independent ambulatory children with lumbosacral spina bifida.
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Anaerobic-to-aerobic power ratio in children with juvenile idiopathic arthritis.
Arthritis Rheum.
PUBLISHED: 05-30-2009
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To examine the anaerobic-to-aerobic power ratio in children with juvenile idiopathic arthritis (JIA) compared with healthy peers.
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Treadmill testing of children who have spina bifida and are ambulatory: does peak oxygen uptake reflect maximum oxygen uptake?
Phys Ther
PUBLISHED: 05-29-2009
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Earlier studies have demonstrated low peak oxygen uptake ((.)Vo(2)peak) in children with spina bifida. Low peak heart rate and low peak respiratory exchange ratio in these studies raised questions regarding the true maximal character of (.)Vo(2)peak values obtained with treadmill testing.
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Motor performance in children with generalized hypermobility: the influence of muscle strength and exercise capacity.
Pediatr Phys Ther
PUBLISHED: 05-15-2009
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The aim of this study was to investigate whether muscle strength and functional exercise capacity (FEC) influence motor performance in children with generalized joint hypermobility.
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Relation between physical fitness and gross motor capacity in children and adolescents with cerebral palsy.
Dev Med Child Neurol
PUBLISHED: 03-24-2009
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To examine the relation between physical fitness and gross motor capacity in children with cerebral palsy (CP) who were classified in Gross Motor Function Classification System levels I or II.
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Is grip strength a predictor for total muscle strength in healthy children, adolescents, and young adults?
Eur. J. Pediatr.
PUBLISHED: 03-08-2009
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The primary purpose of this study was to examine whether grip strength is related to total muscle strength in children, adolescents, and young adults. The second purpose was to provide reference charts for grip strength, which could be used in the clinical and research setting. This cross-sectional study was performed at primary and secondary schools and the University of Applied Sciences. Three hundred and eighty-four healthy Dutch children, adolescents, and young adults at the age of 8 to 20 years participated. Isometric muscle strength was measured with a handheld dynamometer of four muscle groups (shoulder abductors, grip strength, hip flexors, and ankle dorsiflexors). Total muscle strength was a summing up of shoulder abductors, hip flexors, and ankle dorsiflexors. All physical therapists participated in a reliability study. The study was started when intratester and intertester reliability was high (Pearson correlation coefficient >0.8). Grip strength was strongly correlated with total muscle strength, with correlation coefficients between 0.736 and 0.890 (p < 0.01). However, the correlation was weaker when controlled for weight (0.485-0.564, p < 0.01). Grip strength is related to total muscle strength. This indicates, in the clinical setting, that grip strength can be used as a tool to have a rapid indication of someones general muscle strength. The developed reference charts are suitable for evaluating muscle strength in children, adolescents, and young adults in clinical and research settings.
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Six-minute walking test in children with ESRD: discrimination validity and construct validity.
Pediatr. Nephrol.
PUBLISHED: 03-05-2009
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The six-minute walking test (6MWT) may be a practical test for the evaluation functional exercise capacity in children with end-stage renal disease (ESRD). The aim of this study was to investigate the 6MWT performance in children with ESRD compared to reference values obtained in healthy children and, secondly, to study the relationship between 6MWT performance with anthropometric variables, clinical parameters, aerobic capacity and muscle strength. Twenty patients (13 boys and seven girls; mean age 14.1 +/- 3.4 years) on dialysis participated in this study. Anthropometrics were taken in a standardized manner. The 6MWT was performed in a 20-m-long track in a straight hallway. Aerobic fitness was measured using a cycle ergometer test to determine peak oxygen uptake (V O(2peak)), peak rate (W(peak)) and ventilatory threshold (VT). Muscle strength was measured using hand-held myometry. Children with ESRD showed a reduced 6MWT performance (83% of predicted, p < 0.0001), irrespective of the reference values used. The strongest predictors of 6MWT performance were haematocrit and height. Regression models explained 59% (haematocrit and height) to 60% (haematocrit) of the variance in 6MWT performance. 6MWT performance was not associated with V O(2peak), strength, or other anthropometric variables, but it was significantly associated with haematocrit and height. Children with ESRD scored lower on the 6MWT than healthy children. Based on these results, the 6MWT may be a useful instrument for monitoring clinical status in children with ESRD, however it cannot substitute for other fitness tests, such as a progressive exercise test to measure V O(2peak) or muscle strength tests.
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Development, feasibility and efficacy of a community-based exercise training program in pediatric cancer survivors.
Psychooncology
PUBLISHED: 02-27-2009
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The aim of this study was to develop a 12-week exercise training program (comprising aerobic and strength exercises), and to study the feasibility and efficacy of this exercise program in children who survived acute lymphoblastic leukemia.
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Design of a cross-sectional study on physical fitness and physical activity in children and adolescents after burn injury.
BMC Pediatr
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Burn injuries have a major impact on the patients physical and psychological functioning. The consequences can, especially in pediatric burns, persist long after the injury. A decrease in physical fitness seems logical as people survive burn injuries after an often extensive period of decreased activity and an increased demand of proteins leading to catabolism, especially of muscle mass. However, knowledge on the possibly affected levels of physical fitness in children and adolescents after burn injury is limited and pertains only to children with major burns. The current multidimensional study aims to determine the level of physical fitness, the level of physical activity, health-related quality of life and perceived fatigue in children after a burn injury. Furthermore, interrelations between those levels will be explored, as well as associations with burn characteristics.
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Reproducibility of two functional field exercise tests for children with cerebral palsy who self-propel a manual wheelchair.
Dev Med Child Neurol
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The aim of this study was to examine the test-retest reproducibility (reliability and agreement) of the 6-minute push test (6MPT) and the one-stroke push test (1SPT), and construct validity of the 6MPT in children with cerebral palsy (CP) who self-propel a manual wheelchair.
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Are persons with rheumatoid arthritis deconditioned? A review of physical activity and aerobic capacity.
BMC Musculoskelet Disord
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Although the general assumption is that patients with rheumatoid arthritis (RA) have decreased levels of physical activity, no review has addressed whether this assumption is correct.
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Near-infrared spectroscopy during exercise and recovery in children with juvenile dermatomyositis.
Muscle Nerve
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We hypothesized that microvascular disturbances in muscle tissue play a role in the reduced exercise capacity in juvenile dermatomyositis (JDM).
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Reference values for the muscle power sprint test in 6- to 12-year-old children.
Pediatr Phys Ther
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The aims of this study were (1) to develop centile reference values for anaerobic performance of Dutch children tested using the Muscle Power Sprint Test (MPST) and (2) to examine the test-retest reliability of the MPST.
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Motor performance and functional exercise capacity in survivors of pediatric acute lymphoblastic leukemia.
Pediatr Blood Cancer
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Impaired motor performance and reduced maximum exercise capacity during and after treatment of acute lymphoblastic leukemia (ALL) has been shown. However, no longitudinal study monitoring motor performance after cessation of treatment has been published. Whether sub-maximal exercise capacity is reduced is unknown.
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Physiological demands of therapeutic horseback riding in children with moderate to severe motor impairments: an exploratory study.
Pediatr Phys Ther
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To examine energy expenditure at rest and during a single therapeutic horseback riding (THR) session in children with moderate to severe motor impairments.
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Design of the muscles in motion study: a randomized controlled trial to evaluate the efficacy and feasibility of an individually tailored home-based exercise training program for children and adolescents with juvenile dermatomyositis.
BMC Musculoskelet Disord
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Juvenile dermatomyositis (JDM) is a rare, often chronic, systemic autoimmune disease of childhood, characterized by inflammation of the microvasculature of the skeletal muscle and skin. Prominent clinical features include significant exercise intolerance, muscle weakness, and fatigue. Despite pharmacological improvements, these clinical features continue to affect patients with JDM, even when the disease is in remission. Exercise training is increasingly utilized as a non-pharmacological intervention in the clinical management of (adult) patients with chronic inflammatory conditions; however no randomized controlled trials (RCT) have been performed in JDM. In the current study, the efficacy and feasibility of an exercise training program in patients with JDM will be examined.
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Effects of exercise therapy on cardiorespiratory fitness in patients with schizophrenia.
Med Sci Sports Exerc
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Increased mortality in schizophrenia is caused largely by coronary heart disease (CHD). Low cardiorespiratory fitness (CRF) is a key factor for CHD mortality. We compared CRF in patients with schizophrenia to CRF of matched healthy controls and reference values. Also, we examined the effects of exercise therapy on CRF in patients with schizophrenia and in controls.
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Validity and responsiveness of the Dutch McMaster Toronto Arthritis Patient Preference Questionnaire (MACTAR) in patients with osteoarthritis of the hip or knee.
J. Rheumatol.
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To determine the content validity, the construct validity, and the responsiveness of the Dutch McMaster Toronto Arthritis Patient Preference Questionnaire (MACTAR) in patients with osteoarthritis (OA) of the hip or knee.
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Cardiopulmonary exercise testing in cancer rehabilitation: a systematic review.
Sports Med
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This systematic review aims to get insight into the feasibility of cardiopulmonary exercise testing (CPET) in patients with cancer prior to a physical exercise programme. We will focus on quality (defined as the adherence to international guidelines for methods of CPET) and safety of CPET. Furthermore, we compare the peak oxygen uptake (·VO(2peak)) values of patients with cancer with reference values for healthy persons to put these values into a clinical perspective. A computer aided search with cardiopulmonary exercise testing and cancer using MEDLINE, EMBASE, Pedro, CINAHL® and SPORTDiscus™ was carried out. We included studies in which CPET with continuous gas exchange analysis has been performed prior to a physical exercise programme in adults with cancer. Twenty studies describing 1158 patients were eligible. Reported adherence to international recommendations for CPET varied per item. In most studies, the methods of CPET were not reported in detail. Adverse events occurred in 1% of patients. The percentage ·VO(2peak) of reference values for healthy persons varied between 65% and 89% for tests before treatment, between 74% and 96% for tests during treatment and between 52% and 117% for tests after treatment. Our results suggest that CPET is feasible and seems to be safe for patients with cancer prior to a physical exercise programme. We recommend that standard reporting and quality guidelines should be followed for CPET methods. The decreased ·VO(2peak) values of patients with cancer indicate that physical exercise should be implemented in their standard care.
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Validity of the oxygen uptake efficiency slope in children with cystic fibrosis and mild-to-moderate airflow obstruction.
Pediatr Exerc Sci
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The oxygen uptake efficiency slope (OUES) has been proposed as an effort-independent measure of cardiopulmonary exercise capacity, which could be used as an alternative measurement for peak oxygen uptake (VO(2peak)) in populations unable or unwilling to perform maximal exercise. The aim of the current study was to investigate the validity of the OUES in children with cystic fibrosis (CF).
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JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

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In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.