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Find video protocols related to scientific articles indexed in Pubmed.
Radiation pneumonitis in patients with non--small-cell lung cancer treated with erlotinib concurrent with thoracic radiotherapy.
J Thorac Oncol
PUBLISHED: 05-16-2014
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The aim of this study was to investigate the incidence of radiation pneumonitis in patients with non-small-cell lung cancer treated with concurrent thoracic radiotherapy and erlotinib.
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Serum lipid profiles, lipid ratios and Chronic Kidney Disease in a Chinese population.
Int J Environ Res Public Health
PUBLISHED: 05-12-2014
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To examine the association of serum lipids, lipid ratios with Chronic Kidney Disease (CKD) in a Chinese population.
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Robotic stereotactic irradiation and reirradiation for spinal metastases: safety and efficacy assessment.
Chin. Med. J.
PUBLISHED: 01-21-2014
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Spine is the most common site of bone metastases in patients with cancer. Conventional external beam radiotherapy lacks precision to allow delivery of large fraction radiation but simultaneously limit the dose to spinal cord. The purpose of this study was to evaluate the safety and efficacy of CyberKnife(®) radiation therapy for spinal metastases.
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Dose-volume histogram predictors of chronic gastrointestinal complications after radical hysterectomy and postoperative intensity modulated radiotherapy for early-stage cervical cancer.
BMC Cancer
PUBLISHED: 01-11-2014
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The small bowel is one of the critical organs involved in gastrointestinal complications in cervical cancer treated with postoperative intensity modulated radiotherapy. Even with modest doses of radiation therapy (45-50Gy), the risk of severe injury from postoperative radiation therapy is between 5% and 15%. Up to now, a predictive model of acute GI complications of the small bowel has been established with the aid of Quantitative Analyses of Normal Tissue Effects in the Clinic. However, the correlation between dose-volume effect and chronic GI complications of the small bowel has not been extensively investigated. In the article, the correlation has been studied preliminarily.
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Feasibility study of dual energy radiographic imaging for target localization in radiotherapy for lung tumors.
PLoS ONE
PUBLISHED: 01-01-2014
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Dual-energy (DE) radiographic imaging improves tissue discrimination by separating soft from hard tissues in the acquired images. This study was to establish a mathematic model of DE imaging based on intrinsic properties of tissues and quantitatively evaluate the feasibility of applying the DE imaging technique to tumor localization in radiotherapy.
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Multi-scale and shape constrained localized region-based active contour segmentation of uterine fibroid ultrasound images in HIFU therapy.
PLoS ONE
PUBLISHED: 01-01-2014
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To overcome the severe intensity inhomogeneity and blurry boundaries in HIFU (High Intensity Focused Ultrasound) ultrasound images, an accurate and efficient multi-scale and shape constrained localized region-based active contour model (MSLCV), was developed to accurately and efficiently segment the target region in HIFU ultrasound images of uterine fibroids.
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Preliminary analysis of the risk factors for radiation pneumonitis in patients with non-small-cell lung cancer treated with concurrent erlotinib and thoracic radiotherapy.
Onco Targets Ther
PUBLISHED: 01-01-2014
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The aim of this study was to investigate radiation pneumonitis and its associated risk factors in patients with non-small-cell lung cancer treated with concurrent erlotinib and thoracic radiotherapy.
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The theoretical foundation and research progress for WBRT combined with erlotinib for the treatment of multiple brain metastases in patients with lung adenocarcinoma.
Int. J. Cancer
PUBLISHED: 04-16-2013
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Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of lung adenocarcinoma, and a theoretical basis exists for utilising whole brain radiotherapy (WBRT) combined with erlotinib for the treatment for brain metastases in patients with lung adenocarcinoma. This therapeutic regimen has the potential to be a revolutionary treatment for which the most appropriate indication is lung adenocarcinoma. Currently, there is no difference in the treatment of brain metastasis, especially multiple brain metastases, in patients with lung adenocarcinoma of patients with other lung carcinomas. Furthermore, limited clinical trials that combine a TKI with WBRT to treat multiple lung adenocarcinoma metastases have been conducted, and many clinical questions remain unanswered. Lung adenocarcinoma has a high propensity to metastasize to the brain, and targeted therapy has been widely used; however, clinical trials are necessary to provide data to support the combination of erlotinib and WBRT.
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Improved algorithm for gradient vector flow based active contour model using global and local information.
ScientificWorldJournal
PUBLISHED: 01-01-2013
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Active contour models are used to extract object boundary from digital image, but there is poor convergence for the targets with deep concavities. We proposed an improved approach based on existing gradient vector flow methods. Main contributions of this paper are a new algorithm to determine the false part of active contour with higher accuracy from the global force of gradient vector flow and a new algorithm to update the external force field together with the local information of magnetostatic force. Our method has a semidynamic external force field, which is adjusted only when the false active contour exists. Thus, active contours have more chances to approximate the complex boundary, while the computational cost is limited effectively. The new algorithm is tested on irregular shapes and then on real images such as MRI and ultrasound medical data. Experimental results illustrate the efficiency of our method, and the computational complexity is also analyzed.
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Comparative research on the efficacy of CyberKnife® and surgical excision for Stage I hepatocellular carcinoma.
Onco Targets Ther
PUBLISHED: 01-01-2013
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To retrospectively analyze and compare the outcomes of patients with hepatocellular carcinoma treated with either surgical excision or CyberKnife® from September 2006 to August 2011.
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Phase II study of whole brain radiotherapy with or without erlotinib in patients with multiple brain metastases from lung adenocarcinoma.
Drug Des Devel Ther
PUBLISHED: 01-01-2013
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The aim of this paper is to explore the efficacy of whole brain radiotherapy (WBRT) versus WBRT concurrent with erlotinib in patients with multiple brain metastases of lung adenocarcinoma. WBRT was administered at 30Gy/10f in both arms. In the combination arm, 150 mg erlotinib was given each day, starting the first day of radiotherapy and continuing for 1 month following the end of radiotherapy. Thereafter, pemetrexed or docetaxel monotherapy or the best supportive therapy was given to both arms. The intracranial objective response rate and the local progression-free survival (LPFS) were primary endpoints. Toxicity, progression-free survival (PFS) and overall survival (OS) were secondary endpoints. Thirty-one patients in the WBRT group and 23 patients in the combination group were enrolled from November 2009 to December 2011. In the WBRT and the combination arms, respectively, the objective response rate was 54.84% and 95.65% (P = 0.001), the median local progression-free survival was 6.8 months and 10.6 months (P = 0.003), the median PFS was 5.2 months and 6.8 months (P = 0.009), and median OS was 8.9 months and 10.7 months (P = 0.020). In the combination group, there were no differences of LPFS, PFS, and OS between the epidermal growth factor receptor (EGFR) mutation patients and EGFR wild-type patients. No Grade 4 or higher side effects were observed in either group. A multivariate analysis indicated that erlotinib was the most important prognostic factor for a prolonged survival. Data showed that erlotinib in combination with WBRT had a tolerable toxicity profile and prolonged the LPFS, PFS, and OS of lung adenocarcinoma patients with multiple brain metastases compared with WBRT monotherapy.
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Sample training based wildfire segmentation by 2D histogram ?-division with minimum error.
ScientificWorldJournal
PUBLISHED: 01-01-2013
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A novel wildfire segmentation algorithm is proposed with the help of sample training based 2D histogram ?-division and minimum error. Based on minimum error principle and 2D color histogram, the ?-division methods were presented recently, but application of prior knowledge on them has not been explored. For the specific problem of wildfire segmentation, we collect sample images with manually labeled fire pixels. Then we define the probability function of error division to evaluate ?-division segmentations, and the optimal angle ? is determined by sample training. Performances in different color channels are compared, and the suitable channel is selected. To further improve the accuracy, the combination approach is presented with both ?-division and other segmentation methods such as GMM. Our approach is tested on real images, and the experiments prove its efficiency for wildfire segmentation.
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[The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer.].
Zhongguo Fei Ai Za Zhi
PUBLISHED: 10-12-2009
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The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help clinicians to choose proper patients for PORT.
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[Research on Postoperative Radiotherapy for Non-small Cell Lung Cancer of Stage IIIA (N2) according to the Failure Patterns after Pulmonary Resection.].
Zhongguo Fei Ai Za Zhi
PUBLISHED: 10-12-2009
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Postoperative radiotherapy (PORT) after complete resection of non-small cell lung cancer (NSCLC) has been introduced in order to reduce locoregional recurrence, but it remains controversy whether PORT can improve survival. Therefore, we want to investigate the effect of PORT and the relationship between failure patterns and primarily location of stage IIIA (N2) in NSCLC.
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Geological events play a larger role than Pleistocene climatic fluctuations in driving the genetic structure of Quasipaa boulengeri (Anura: Dicroglossidae).
Mol. Ecol.
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Paleoclimatic and paleogeological events have been identified as being the two main drivers of genetic structuring in extant organisms. We used a montane stream-dwelling frog, Quasipaa boulengeri, to explore the relative roles played by these drivers on species in southern China, a region needing thorough studies. We detected four major matrilines, and no broadly distributed haplotypes occurred. The complex orogenesis of south-western China drove matrilineal divergence in Q. boulengeri into highly structured geographical units. These matrilines subsequently persisted in situ with stable populations rather than undergoing expansions during glacial cycling. The unification of the upper and middle Yangtze River in the Three Gorges mountain region mediated downstream colonization of this frog. Analyses identified geological events as playing a larger role than climatic fluctuations in driving the population history of Q. boulengeri. Nuclear allele analyses indicated gene flow; this maintained genetic cohesion of the species. South-eastern Sichuan Basin was identified as the area of secondary contact for several matrilines, and this area deserves further study and special protection.
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Automated volumetric modulated Arc therapy treatment planning for stage III lung cancer: how does it compare with intensity-modulated radio therapy?
Int. J. Radiat. Oncol. Biol. Phys.
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To compare the quality of volumetric modulated arc therapy (VMAT) or intensity-modulated radiation therapy (IMRT) plans generated by an automated inverse planning system with that of dosimetrist-generated IMRT treatment plans for patients with stage III lung cancer.
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Factors affecting the risk of brain metastasis in small cell lung cancer with surgery: is prophylactic cranial irradiation necessary for stage I-III disease?
Int. J. Radiat. Oncol. Biol. Phys.
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The use of prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC) with surgical resection has not been fully identified. This study undertook to assess the factors affecting the risk of brain metastases in patients with stage I-III SCLC after surgical resection. The implications of PCI treatment for these patients are discussed.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.