Akira Miyazaki Department of Biochemistry Showa University School of Medicine Biography Publications Institution JoVE Articles Akira Miyazaki has not added a biography. If you are Akira Miyazaki and would like to personalize this page please email our Author Liaison for assistance. Publications Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future Current Pharmaceutical Design. 2019 | Pubmed ID: 30892155 Endothelial Calpain Systems Orchestrate Myofibroblast Differentiation During Wound Healing FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2019 | Pubmed ID: 30199285 Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling Current Medicinal Chemistry. 2019 | Pubmed ID: 29589525 Expression of Steroidogenic Enzymes and Metabolism of Steroids in COS-7 Cells Known As Non-steroidogenic Cells Scientific Reports. 02, 2018 | Pubmed ID: 29391479 The Impact of Stromal Hic-5 on the Tumorigenesis of Colorectal Cancer Through Lysyl Oxidase Induction and Stromal Remodeling Oncogene. 03, 2018 | Pubmed ID: 29242607 Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders Journal of Atherosclerosis and Thrombosis. Jan, 2018 | Pubmed ID: 28819082 Emerging Roles of Calpain Proteolytic Systems in Macrophage Cholesterol Handling Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28432377 Differential Lactate and Cholesterol Synthetic Activities in XY and XX Sertoli Cells Scientific Reports. 02, 2017 | Pubmed ID: 28150810 Potential Contribution of the Hepcidin-macrophage Axis to Plaque Vulnerability in Acute Myocardial Infarction in Human International Journal of Cardiology. Jan, 2017 | Pubmed ID: 27855289 Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases Journal of Atherosclerosis and Thrombosis. Jan, 2017 | Pubmed ID: 27476665 Priming with Erythropoietin Enhances Cell Survival and Angiogenic Effect of Mesenchymal Stem Cell Implantation in Rat Limb Ischemia Regenerative Therapy. Jun, 2016 | Pubmed ID: 31245482 Calpain-6 Confers Atherogenicity to Macrophages by Dysregulating Pre-mRNA Splicing The Journal of Clinical Investigation. 09, 2016 | Pubmed ID: 27525442 Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke Journal of Molecular Neuroscience : MN. Jun, 2016 | Pubmed ID: 26910758 Fibroblast Growth Factor-23 Induces Cellular Senescence in Human Mesenchymal Stem Cells from Skeletal Muscle Biochemical and Biophysical Research Communications. Feb, 2016 | Pubmed ID: 26797283 Hic-5 Deficiency Attenuates the Activation of Hepatic Stellate Cells and Liver Fibrosis Through Upregulation of Smad7 in Mice Journal of Hepatology. Jan, 2016 | Pubmed ID: 26334580 Hydrogen Peroxide-inducible Clone-5 Regulates Mesangial Cell Proliferation in Proliferative Glomerulonephritis in Mice PloS One. 2015 | Pubmed ID: 25835392 Calpastatin Counteracts Pathological Angiogenesis by Inhibiting Suppressor of Cytokine Signaling 3 Degradation in Vascular Endothelial Cells Circulation Research. Mar, 2015 | Pubmed ID: 25648699 Role of Hic-5 in the Formation of Microvilli-like Structures and the Monocyte-endothelial Interaction That Accelerates Atherosclerosis Cardiovascular Research. Mar, 2015 | Pubmed ID: 25587044 NADPH Oxidase Deficiency Exacerbates Angiotensin II-induced Abdominal Aortic Aneurysms in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2014 | Pubmed ID: 25189573 Identification of Hic-5 As a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms Journal of the American Heart Association. May, 2014 | Pubmed ID: 24811612 Time Course-changes in Phosphatidylcholine Profile During Oxidative Modification of Low-density Lipoprotein Lipids in Health and Disease. Mar, 2014 | Pubmed ID: 24625108 Calpain and Atherosclerosis Journal of Atherosclerosis and Thrombosis. 2013 | Pubmed ID: 23171729 Salusin-β Accelerates Inflammatory Responses in Vascular Endothelial Cells Via NF-κB Signaling in LDL Receptor-deficient Mice in Vivo and HUVECs in Vitro American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012 | Pubmed ID: 22561298 Coexpression of CCR6 and CD146 (MCAM) is a Marker of Effector Memory T-helper 17 Cells The Journal of Dermatology. Oct, 2012 | Pubmed ID: 22486269 Hydrogen Peroxide-inducible Clone 5 (Hic-5) As a Potential Therapeutic Target for Vascular and Other Disorders Journal of Atherosclerosis and Thrombosis. 2012 | Pubmed ID: 22472216 Effects of PKF275-055, a Dipeptidyl Peptidase-4 Inhibitor, on the Development of Atherosclerotic Lesions in Apolipoprotein E-null Mice Metabolism: Clinical and Experimental. Jul, 2012 | Pubmed ID: 22225957 M-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-cadherin Disorganization and Atherosclerosis Circulation. Dec, 2011 | Pubmed ID: 22064597 Purification of Recombinant Acyl-coenzyme A:cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies Between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy Biochemistry. Nov, 2010 | Pubmed ID: 20964445 Chronic Infusion of Salusin-alpha and -beta Exerts Opposite Effects on Atherosclerotic Lesion Development in Apolipoprotein E-deficient Mice Atherosclerosis. Sep, 2010 | Pubmed ID: 20684826 Preventive Effects of Heregulin-beta1 on Macrophage Foam Cell Formation and Atherosclerosis Circulation Research. Aug, 2009 | Pubmed ID: 19644050 Increased Plasma Urotensin-II and Carotid Atherosclerosis Are Associated with Vascular Dementia Journal of Atherosclerosis and Thrombosis. Jun, 2009 | Pubmed ID: 19638714 Leptin Modulates ACAT1 Expression and Cholesterol Efflux from Human Macrophages American Journal of Physiology. Endocrinology and Metabolism. Aug, 2009 | Pubmed ID: 19625677 Human Urotensin II Promotes Hypertension and Atherosclerotic Cardiovascular Diseases Current Medicinal Chemistry. 2009 | Pubmed ID: 19199921 Angiotensin II Upregulates Acyl-CoA:cholesterol Acyltransferase-1 Via the Angiotensin II Type 1 Receptor in Human Monocyte-macrophages Hypertension Research : Official Journal of the Japanese Society of Hypertension. Sep, 2008 | Pubmed ID: 18971559 Chronic Urotensin II Infusion Enhances Macrophage Foam Cell Formation and Atherosclerosis in Apolipoprotein E-knockout Mice Journal of Hypertension. Oct, 2008 | Pubmed ID: 18806619 Serum Salusin-alpha Levels Are Decreased and Correlated Negatively with Carotid Atherosclerosis in Essential Hypertensive Patients Hypertension Research : Official Journal of the Japanese Society of Hypertension. Mar, 2008 | Pubmed ID: 18497465 Increased Plasma Urotensin-II Levels Are Associated with Diabetic Retinopathy and Carotid Atherosclerosis in Type 2 Diabetes Clinical Science (London, England : 1979). Dec, 2008 | Pubmed ID: 18338983 Impact of Salusin-alpha and -beta on Human Macrophage Foam Cell Formation and Coronary Atherosclerosis Circulation. Feb, 2008 | Pubmed ID: 18212280 Use of Serum Insulin-like Growth Factor-I Levels to Predict Psychiatric Non-response to Donepezil in Patients with Alzheimer's Disease Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2008 | Pubmed ID: 17714966 Increased Human Urotensin II Levels Are Correlated with Carotid Atherosclerosis in Essential Hypertension American Journal of Hypertension. Feb, 2007 | Pubmed ID: 17261470 Impact of Increased Plasma Serotonin Levels and Carotid Atherosclerosis on Vascular Dementia Atherosclerosis. Nov, 2007 | Pubmed ID: 17049533 Human Urotensin-II Potentiates the Mitogenic Effect of Mildly Oxidized Low-density Lipoprotein on Vascular Smooth Muscle Cells: Comparison with Other Vasoactive Agents and Hydrogen Peroxide Hypertension Research : Official Journal of the Japanese Society of Hypertension. Oct, 2006 | Pubmed ID: 17283870 Human Urotensin II As a Link Between Hypertension and Coronary Artery Disease Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jun, 2006 | Pubmed ID: 16940699 Ndrg4 Enhances NGF-induced ERK Activation Uncoupled with Elk-1 Activation Journal of Cellular Biochemistry. May, 2006 | Pubmed ID: 16408304 Serotonin Acts As an Up-regulator of Acyl-coenzyme A:cholesterol Acyltransferase-1 in Human Monocyte-macrophages Atherosclerosis. Jun, 2006 | Pubmed ID: 16157345 Inhibitors of Acyl-coenzyme A: Cholesterol Acyltransferase Current Drug Targets. Cardiovascular & Haematological Disorders. Dec, 2005 | Pubmed ID: 16503866 Relationship Between Serum Insulin-like Growth Factor-1 Levels and Alzheimer's Disease and Vascular Dementia Journal of the American Geriatrics Society. Oct, 2005 | Pubmed ID: 16181175 Human Urotensin II Accelerates Foam Cell Formation in Human Monocyte-derived Macrophages Hypertension (Dallas, Tex. : 1979). Oct, 2005 | Pubmed ID: 16172428 High Prevalence of Chlamydia Pneumoniae Antibodies and Increased High-sensitive C-reactive Protein in Patients with Vascular Dementia Journal of the American Geriatrics Society. Apr, 2005 | Pubmed ID: 15817002 [Acyl-coenzyme A: Cholesterol Acyltransferase (ACAT)] Nihon Rinsho. Japanese Journal of Clinical Medicine. Dec, 2004 | Pubmed ID: 15658270 Genomic Organization, Expression, and Comparative Analysis of Noncoding Region of the Rat Ndrg4 Gene Gene. Jan, 2004 | Pubmed ID: 14693380 Acyl-coenzyme A:cholesterol Acyltransferase Inhibitors for Controlling Hypercholesterolemia and Atherosclerosis Current Opinion in Investigational Drugs (London, England : 2000). Sep, 2003 | Pubmed ID: 14582454 Advanced Glycation End Products (AGE) Inhibit Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport: a New Crossroad of AGE to Cholesterol Metabolism Journal of Atherosclerosis and Thrombosis. 2003 | Pubmed ID: 12621157 온-막 소화 기술을 사용한 단백질-단백질 상호 작용의 평가 Takashi Obama*1, Takuro Miyazaki*2, Toshihiro Aiuchi1, Akira Miyazaki2, Hiroyuki Itabe1 1Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, 2Department of Biochemistry, Showa University School of Medicine JoVE 59733 Biochemistry
온-막 소화 기술을 사용한 단백질-단백질 상호 작용의 평가 Takashi Obama*1, Takuro Miyazaki*2, Toshihiro Aiuchi1, Akira Miyazaki2, Hiroyuki Itabe1 1Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, 2Department of Biochemistry, Showa University School of Medicine JoVE 59733 Biochemistry