Akira Sawa

Publications

• Environmental Stresso, Rs and Epigenetic Control of the Hypothalamic-Pituitary-Adrenal-Axis (HPA-axis)
  Neuroendocrinology. Nov, 2014  |   Pubmed ID: 25427939
• Role of Apoptosis Signal-regulating Kinase 1 (ASK1) As an Activator of the GAPDH-Siah1 Stress-Signaling Cascade
  The Journal of Biological Chemistry. Nov, 2014  |   Pubmed ID: 25391652
• Is Prophylactic Psychiatry Around the Corner? Combating Adolescent Oxidative Stress for Adult Psychosis and Schizophrenia
  Neuron. Sep, 2014  |   Pubmed ID: 25189204
• Neuropeptide Precursor VGF is Genetically Associated with Social Anhedonia and Underrepresented in the Brain of Major Mental Illness: Its Downregulation by DISC1
  Human Molecular Genetics. Nov, 2014  |   Pubmed ID: 24934694
• Human Stem Cells and Surrogate Tissues for Basic and Translational Study of Mental Disorders
  Biological Psychiatry. Jun, 2014  |   Pubmed ID: 24862565
• Inflammatory Molecular Signature Associated with Infectious Agents in Psychosis
  Schizophrenia Bulletin. Sep, 2014  |   Pubmed ID: 24743863
• Reasons for Not Seeking General Medical Care Among Individuals with Serious Mental Illness
  Psychiatric Services (Washington, D.C.). Jun, 2014  |   Pubmed ID: 24733659
• PAKs Inhibitors Ameliorate Schizophrenia-associated Dendritic Spine Deterioration in Vitro and in Vivo During Late Adolescence
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014  |   Pubmed ID: 24706880
• Oxidative Stress and Schizophrenia: Recent Breakthroughs from an Old Story
  Current Opinion in Psychiatry. May, 2014  |   Pubmed ID: 24613987
• Regional Brain Distribution of Translocator Protein Using [(11)C]DPA-713 PET in Individuals Infected with HIV
  Journal of Neurovirology. Jun, 2014  |   Pubmed ID: 24567030
• Promoting Careers in Academic Research to Psychiatry Residents
  Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry. Apr, 2014  |   Pubmed ID: 24497181
• Modeling Heterogeneous Patients with a Clinical Diagnosis of Schizophrenia with Induced Pluripotent Stem Cells
  Biological Psychiatry. Jun, 2014  |   Pubmed ID: 24331955
• Hippocampal Volume Reduction Correlates with Apathy in Traumatic Brain Injury, but Not Schizophrenia
  The Journal of Neuropsychiatry and Clinical Neurosciences. 2013  |   Pubmed ID: 24247856
• Olfactory Cells Via Nasal Biopsy Reflect the Developing Brain in Gene Expression Profiles: Utility and Limitation of the Surrogate Tissues in Research for Brain Disorders
  Neuroscience Research. Dec, 2013  |   Pubmed ID: 24120685
• Deficits in MicroRNA-mediated Cxcr4/Cxcl12 Signaling in Neurodevelopmental Deficits in a 22q11 Deletion Syndrome Mouse Model
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013  |   Pubmed ID: 24101523
• Reduced Anterior Cingulate Gray Matter Volume and Thickness in Subjects with Deficit Schizophrenia
  Schizophrenia Research. Nov, 2013  |   Pubmed ID: 24035178
• Regulation of N-Methyl-D-Aspartate Receptors by Disrupted-in-Schizophrenia-1
  Biological Psychiatry. Jul, 2013  |   Pubmed ID: 23906531
• Relationships Between Serum Leptin Level and Severity of Positive Symptoms in Schizophrenia
  Neuroscience Research. Sep-Oct, 2013  |   Pubmed ID: 23896201
• Cuprizone Short-term Exposure: Astrocytic IL-6 Activation and Behavioral Changes Relevant to Psychosis
  Neurobiology of Disease. Nov, 2013  |   Pubmed ID: 23867234
• Cognitive and Motivational Deficits Together with Prefrontal Oxidative Stress in a Mouse Model for Neuropsychiatric Illness
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013  |   Pubmed ID: 23840059
• Mouse Models of Gene-environment Interactions in Schizophrenia
  Neurobiology of Disease. Sep, 2013  |   Pubmed ID: 23748077
• MicroRNA-382 Expression is Elevated in the Olfactory Neuroepithelium of Schizophrenia Patients
  Neurobiology of Disease. Jul, 2013  |   Pubmed ID: 23542694
• Astroglial IFITM3 Mediates Neuronal Impairments Following Neonatal Immune Challenge in Mice
  Glia. May, 2013  |   Pubmed ID: 23382131
• Schizophrenia Research in 2013: Are We Making Progress?
  Neurobiology of Disease. May, 2013  |   Pubmed ID: 23380149
• Synapse-specific Contributions in the Cortical Pathology of Schizophrenia
  Neurobiology of Disease. May, 2013  |   Pubmed ID: 23336981
• Adolescent Stress-induced Epigenetic Control of Dopaminergic Neurons Via Glucocorticoids
  Science (New York, N.Y.). Jan, 2013  |   Pubmed ID: 23329051
• Subcortical Dopaminergic Deficits in a DISC1 Mutant Model: a Study in Direct Reference to Human Molecular Brain Imaging
  Human Molecular Genetics. Apr, 2013  |   Pubmed ID: 23314019
• DISC1: a Key Lead in Studying Cortical Development and Associated Brain Disorders
  The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Oct, 2013  |   Pubmed ID: 23300216
• DISC1 As a Therapeutic Target for Mental Illnesses
  Expert Opinion on Therapeutic Targets. Dec, 2012  |   Pubmed ID: 23130881
• Diabetes is Associated with Lower Global Cognitive Function in Schizophrenia
  Schizophrenia Research. Dec, 2012  |   Pubmed ID: 23031192
• PKA and PDE4D3 Anchoring to AKAP9 Provides Distinct Regulation of CAMP Signals at the Centrosome
  The Journal of Cell Biology. Aug, 2012  |   Pubmed ID: 22908311
• Pharmacokinetics of Oral D-serine in D-amino Acid Oxidase Knockout Mice
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. Nov, 2012  |   Pubmed ID: 22837388
• Proteomic, Approcci Genomici E Traslazionali Identificano CRMP1 Per Un Ruolo Nella Schizofrenia E Tratti Sottostante
  Human Molecular Genetics. Aug, 2012  |   Pubmed ID: 22798627
• KCTD13 is a Major Driver of Mirrored Neuroanatomical Phenotypes of the 16p11.2 Copy Number Variant
  Nature. May, 2012  |   Pubmed ID: 22596160
• Perdita Indotta Da Glucocorticoidi Di Metilazione Del DNA Nelle Cellule Non-neuronali E Potenziale Coinvolgimento Di DNMT1 Nella Regolazione Epigenetica Del Fkbp5
  Biochemical and Biophysical Research Communications. Apr, 2012  |   Pubmed ID: 22445894
• Better Understanding of Mechanisms of Schizophrenia and Bipolar Disorder: from Human Gene Expression Profiles to Mouse Models
  Neurobiology of Disease. Jan, 2012  |   Pubmed ID: 21914480
• Protein S-nitrosylation: Role for Nitric Oxide Signaling in Neuronal Death
  Biochimica Et Biophysica Acta. Jun, 2012  |   Pubmed ID: 21803124
• Mouse Strain Differences in Phencyclidine-induced Behavioural Changes
  The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Jul, 2012  |   Pubmed ID: 21733237
• In Utero Electroporation As a Tool for Genetic Manipulation in Vivo to Study Psychiatric Disorders: from Genes to Circuits and Behaviors
  The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Apr, 2012  |   Pubmed ID: 21551077
• Anti-/Propsychotic Drug Signaling Via Heteromeric GPCRs--a Balancing Act?
  Cell. Nov, 2011  |   Pubmed ID: 22118451
• Linking Neurodevelopmental and Synaptic Theories of Mental Illness Through DISC1
  Nature Reviews. Neuroscience. Dec, 2011  |   Pubmed ID: 22095064
• Following the Genes: a Framework for Animal Modeling of Psychiatric Disorders
  BMC Biology. 2011  |   Pubmed ID: 22078115
• Avanzando La Scoperta Di Farmaci Per La Schizofrenia
  Annals of the New York Academy of Sciences. Oct, 2011  |   Pubmed ID: 22032400
• DISC1 at 10: Connecting Psychiatric Genetics and Neuroscience
  Trends in Molecular Medicine. Dec, 2011  |   Pubmed ID: 22015021
• Epitelio Olfattivo Umano Nasale Come Marker Dinamico Per Lo Sviluppo Di Terapia Di CNS
  Experimental Neurology. Dec, 2011  |   Pubmed ID: 21945230
• The Insula-claustrum Region and Delusions in Schizophrenia
  Schizophrenia Research. Dec, 2011  |   Pubmed ID: 21875780
• Effects of Antipsychotics on the Behavioral Deficits in Human Dominant-negative DISC1 Transgenic Mice with Neonatal PolyI:C Treatment
  Behavioural Brain Research. Nov, 2011  |   Pubmed ID: 21835207
• Altered MHC Class I Expression in Dorsolateral Prefrontal Cortex of Nonsmoker Patients with Schizophrenia
  Neuroscience Research. Nov, 2011  |   Pubmed ID: 21801761
• DISC1 Regulates Synaptic Vesicle Transport Via a Lithium-sensitive Pathway
  Neuroscience Research. Sep, 2011  |   Pubmed ID: 21664390
• Readdressing Synaptic Pruning Theory for Schizophrenia: Combination of Brain Imaging and Cell Biology
  Communicative & Integrative Biology. Mar, 2011  |   Pubmed ID: 21655443
• Chinasi Di Inositolo Hexakisphosphate Inducono La Morte Delle Cellule Nella Malattia Di Huntington
  The Journal of Biological Chemistry. Jul, 2011  |   Pubmed ID: 21652713
• Glutathione is a Physiologic Reservoir of Neuronal Glutamate
  Biochemical and Biophysical Research Communications. Jun, 2011  |   Pubmed ID: 21539809
• Working Memory Deficits in Neuronal Nitric Oxide Synthase Knockout Mice: Potential Impairments in Prefrontal Cortex Mediated Cognitive Function
  Biochemical and Biophysical Research Communications. May, 2011  |   Pubmed ID: 21539806
• DISC1-dependent Switch from Progenitor Proliferation to Migration in the Developing Cortex
  Nature. May, 2011  |   Pubmed ID: 21471969
• Impaired NMDA Receptor Transmission Alters Striatal Synapses and DISC1 Protein in an Age-dependent Manner
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011  |   Pubmed ID: 21436042
• A Novel Balanced Chromosomal Translocation Found in Subjects with Schizophrenia and Schizotypal Personality Disorder: Altered L-serine Level Associated with Disruption of PSAT1 Gene Expression
  Neuroscience Research. Feb, 2011  |   Pubmed ID: 20955740
• Nitric Oxide Signaling and Nitrosative Stress in Neurons: Role for S-nitrosylation
  Antioxidants & Redox Signaling. Apr, 2011  |   Pubmed ID: 20812870
• The Diverse Functions of GAPDH: Views from Different Subcellular Compartments
  Cellular Signalling. Feb, 2011  |   Pubmed ID: 20727968
• Interazione Prenatale Del Mutante DISC1 E Attivazione Immunitaria Produce Psicopatologia Degli Adulti
  Biological Psychiatry. Dec, 2010  |   Pubmed ID: 21130225
• Biochimica E Funzionale Interazione Perturbato-in-schizofrenia 1 E Proteina Precursore Dell'amiloide Regola La Migrazione Neuronale Durante Lo Sviluppo Corticale Dei Mammiferi
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010  |   Pubmed ID: 20685985
• Assessing the Role of Endooligopeptidase Activity of Ndel1 (nuclear-distribution Gene E Homolog Like-1) in Neurite Outgrowth
  Molecular and Cellular Neurosciences. Aug, 2010  |   Pubmed ID: 20462516
• Gray-matter Abnormalities in Deficit Schizophrenia
  Schizophrenia Research. Jul, 2010  |   Pubmed ID: 20452187
• Disturbed Synaptic Connectivity in Schizophrenia: Convergence of Genetic Risk Factors During Neurodevelopment
  Brain Research Bulletin. Sep, 2010  |   Pubmed ID: 20433911
• Interrotto-in-schizofrenia-1 Espressione è Regolato Dalla Proteina Precursore Dell'amiloide Beta-sito Fendendo Enzima-1-neuregulina Cascade
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20212127
• Knockdown of DISC1 by in Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits
  Neuron. Feb, 2010  |   Pubmed ID: 20188653
• Neuroanatomic and Cognitive Abnormalities Related to Herpes Simplex Virus Type 1 in Schizophrenia
  Schizophrenia Research. May, 2010  |   Pubmed ID: 20153952
• Interrotto-in-schizofrenia 1 (DISC1) Regola Spine Della Sinapsi Glutammato Via Rac1
  Nature Neuroscience. Mar, 2010  |   Pubmed ID: 20139976
• A Novel Role for Glyceraldehyde-3-phosphate Dehydrogenase and Monoamine Oxidase B Cascade in Ethanol-induced Cellular Damage
  Biological Psychiatry. May, 2010  |   Pubmed ID: 20022592
• Review of Pathological Hallmarks of Schizophrenia: Comparison of Genetic Models with Patients and Nongenetic Models
  Schizophrenia Bulletin. Mar, 2010  |   Pubmed ID: 19903746
• Negative Symptoms of Schizophrenia Correlate with Impairment on the University of Pennsylvania Smell Identification Test
  Neuroscience Research. Jan, 2010  |   Pubmed ID: 19819272
• Combined Effect of Neonatal Immune Activation and Mutant DISC1 on Phenotypic Changes in Adulthood
  Behavioural Brain Research. Jan, 2010  |   Pubmed ID: 19716847
• Genetic Animal Models for Schizophrenia: Advantages and Limitations of Genetic Manipulation in Drosophila, Zebrafish, Rodents, and Primates
  Progress in Brain Research. 2009  |   Pubmed ID: 20302812
• Preface. This Volume Focuses on How Genetic Models for Schizophrenia, That Is, Manipulation in Genetic Susceptibility Factors for the Disease, Have Potential in Opening a New Window of Better Understanding of Etiology-relevant Mechanisms
  Progress in Brain Research. 2009  |   Pubmed ID: 19932335
• Glyceraldehyde-3-phosphate Dehydrogenase Aggregate Formation Participates in Oxidative Stress-induced Cell Death
  The Journal of Biological Chemistry. Dec, 2009  |   Pubmed ID: 19837666
• Comprensione Del Ruolo Di DISC1 Nella Malattia Psichiatrica E Durante Lo Sviluppo Normale
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009  |   Pubmed ID: 19828788
• A Novel Role for HGas7b in Microtubular Maintenance: Possible Implication in Tau-associated Pathology in Alzheimer Disease
  The Journal of Biological Chemistry. Nov, 2009  |   Pubmed ID: 19801671
• Neurodevelopmental Mechanisms of Schizophrenia: Understanding Disturbed Postnatal Brain Maturation Through Neuregulin-1-ErbB4 and DISC1
  Trends in Neurosciences. Sep, 2009  |   Pubmed ID: 19712980
• Cortical Development and Glutamatergic Dysregulation in Schizophrenia
  Biological Psychiatry. Sep, 2009  |   Pubmed ID: 19712774
• Using Bioinformatic Tools
  The American Journal of Psychiatry. Aug, 2009  |   Pubmed ID: 19651749
• GOSPEL: a Neuroprotective Protein That Binds to GAPDH Upon S-nitrosylation
  Neuron. Jul, 2009  |   Pubmed ID: 19607794
• Animal Models of Gene-environment Interactions in Schizophrenia
  Behavioural Brain Research. Dec, 2009  |   Pubmed ID: 19379776
• Schizophrenia and Epilepsy: is There a Shared Susceptibility?
  Neuroscience Research. Apr, 2009  |   Pubmed ID: 19367784
• Peripheral Olfactory System for Clinical and Basic Psychiatry: a Promising Entry Point to the Mystery of Brain Mechanism and Biomarker Identification in Schizophrenia
  The American Journal of Psychiatry. Feb, 2009  |   Pubmed ID: 19188289
• Proteomic and Histochemical Analysis of Proteins Involved in the Dying-back-type of Axonal Degeneration in the Gracile Axonal Dystrophy (gad) Mouse
  Neurochemistry International. May-Jun, 2009  |   Pubmed ID: 19154771
• Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4: a Candidate for Psychiatric Illnesses
  Archives of General Psychiatry. Sep, 2008  |   Pubmed ID: 18762586
• Nitric Oxide-induced Nuclear GAPDH Activates P300/CBP and Mediates Apoptosis
  Nature Cell Biology. Jul, 2008  |   Pubmed ID: 18552833
• Elucidating the Relationship Between DISC1, NDEL1 and NDE1 and the Risk for Schizophrenia: Evidence of Epistasis and Competitive Binding
  Human Molecular Genetics. Aug, 2008  |   Pubmed ID: 18469341