Alison L. Allan London Regional Cancer Program Biography Publications Institution JoVE Articles Alison L. Allan has not added a biography. If you are Alison L. Allan and would like to personalize this page please email our Author Liaison for assistance. Publications Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment Cancers. Jan, 2020 | Pubmed ID: 31936750 Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response Cancers. Aug, 2019 | Pubmed ID: 31450577 On-Chip Preparation of Amphiphilic Nanomicelles-in-Sodium Alginate Spheroids As a Novel Platform Against Triple-Negative Human Breast Cancer Cells: Fabrication, Study of Microfluidics Flow Hydrodynamics and Proof of Concept for Anticancer and Drug Delivery Applications Journal of Pharmaceutical Sciences. 11, 2019 | Pubmed ID: 31351864 Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives International Journal of Molecular Sciences. May, 2019 | Pubmed ID: 31071959 A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205 Clinical Genitourinary Cancer. 06, 2019 | Pubmed ID: 31056399 Magnetically Guided Self-Assembled Protein Micelles for Enhanced Delivery of Dasatinib to Human Triple-Negative Breast Cancer Cells Journal of Pharmaceutical Sciences. 05, 2019 | Pubmed ID: 30528944 Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells As a Predictive Biomarker for Castration-Resistant Prostate Cancer JAMA Oncology. 09, 2018 | Pubmed ID: 29955787 Circulating Tumor Cell Analysis in Preclinical Mouse Models of Metastasis Diagnostics (Basel, Switzerland). Apr, 2018 | Pubmed ID: 29710776 Self-assembled Amphiphilic Zein-lactoferrin Micelles for Tumor Targeted Co-delivery of Rapamycin and Wogonin to Breast Cancer European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Jul, 2018 | Pubmed ID: 29689288 Circulating Tumor Cells and Implications of the Epithelial-to-Mesenchymal Transition Advances in Clinical Chemistry. 2018 | Pubmed ID: 29304900 Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells International Journal of Molecular Sciences. Sep, 2017 | Pubmed ID: 28937653 Soluble Bone-derived Osteopontin Promotes Migration and Stem-like Behavior of Breast Cancer Cells PloS One. 2017 | Pubmed ID: 28498874 Epithelial-to-mesenchymal Transition Leads to Disease-stage Differences in Circulating Tumor Cell Detection and Metastasis in Pre-clinical Models of Prostate Cancer Oncotarget. Nov, 2016 | Pubmed ID: 27764810 Circulating Tumor Cells (CTC) and Cell-Free DNA (cfDNA) Workshop 2016: Scientific Opportunities and Logistics for Cancer Clinical Trial Incorporation International Journal of Molecular Sciences. Sep, 2016 | Pubmed ID: 27618023 Central, But Not Peripheral, Circulating Tumor Cells Are Prognostic in Patients Undergoing Resection of Colorectal Cancer Liver Metastases Annals of Surgical Oncology. Jul, 2016 | Pubmed ID: 26714949 Aldehyde Dehydrogenase As a Marker and Functional Mediator of Metastasis in Solid Tumors Clinical & Experimental Metastasis. Jan, 2016 | Pubmed ID: 26445849 Lung-derived Factors Mediate Breast Cancer Cell Migration Through CD44 Receptor-ligand Interactions in a Novel Ex Vivo System for Analysis of Organ-specific Soluble Proteins Neoplasia (New York, N.Y.). Feb, 2014 | Pubmed ID: 24709425 Recent Advances in the Molecular Characterization of Circulating Tumor Cells Cancers. 2014 | Pubmed ID: 24633084 User-defined Protein Marker Assay Development for Characterization of Circulating Tumor Cells Using the CellSearch® System Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2012 | Pubmed ID: 22899576 The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance Between the "Seed" and the "Soil"? International Journal of Breast Cancer. 2012 | Pubmed ID: 22295241 Image Cytometry Analysis of Circulating Tumor Cells Methods in Cell Biology. 2011 | Pubmed ID: 21704842 Migratory Strategies of Normal and Malignant Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21618081 Deletion of the Thrombin Cleavage Domain of Osteopontin Mediates Breast Cancer Cell Adhesion, Proteolytic Activity, Tumorgenicity, and Metastasis BMC Cancer. 2011 | Pubmed ID: 21247495 Circulating Tumor Cell Analysis: Technical and Statistical Considerations for Application to the Clinic Journal of Oncology. 2010 | Pubmed ID: 20049168 Lymphatic Metastasis of Breast Cancer Cells is Associated with Differential Gene Expression Profiles That Predict Cancer Stem Cell-like Properties and the Ability to Survive, Establish and Grow in a Foreign Environment International Journal of Oncology. Aug, 2009 | Pubmed ID: 19578743 Characterization of Tumor Cell Dissemination Patterns in Preclinical Models of Cancer Metastasis Using Flow Cytometry and Laser Scanning Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2009 | Pubmed ID: 18855920 High Aldehyde Dehydrogenase and Expression of Cancer Stem Cell Markers Selects for Breast Cancer Cells with Enhanced Malignant and Metastatic Ability Journal of Cellular and Molecular Medicine. Aug, 2009 | Pubmed ID: 18681906 Downregulation of Osteopontin Contributes to Metastasis Suppression by Breast Cancer Metastasis Suppressor 1 International Journal of Cancer. Journal International Du Cancer. Aug, 2008 | Pubmed ID: 18470911 The Thrombin Inhibitor Argatroban Reduces Breast Cancer Malignancy and Metastasis Via Osteopontin-dependent and Osteopontin-independent Mechanisms Breast Cancer Research and Treatment. Nov, 2008 | Pubmed ID: 18097747 Osteopontin Overexpression in Breast Cancer: Knowledge Gained and Possible Implications for Clinical Management Journal of Cellular Biochemistry. Nov, 2007 | Pubmed ID: 17721886 Tumor Dormancy and Cancer Stem Cells: Implications for the Biology and Treatment of Breast Cancer Metastasis Breast Disease. 2006-2007 | Pubmed ID: 17473368 Tumor Dormancy and the Role of Metastasis Suppressor Genes in Regulating Ectopic Growth Future Oncology (London, England). Oct, 2006 | Pubmed ID: 17026454 Role of the Integrin-binding Protein Osteopontin in Lymphatic Metastasis of Breast Cancer The American Journal of Pathology. Jul, 2006 | Pubmed ID: 16816376 A New Model for Lymphatic Metastasis: Development of a Variant of the MDA-MB-468 Human Breast Cancer Cell Line That Aggressively Metastasizes to Lymph Nodes Clinical & Experimental Metastasis. 2005 | Pubmed ID: 16170671 Detection and Quantification of Circulating Tumor Cells in Mouse Models of Human Breast Cancer Using Immunomagnetic Enrichment and Multiparameter Flow Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2005 | Pubmed ID: 15810015 Isolamento e valutazione funzionale di cellule staminali di cancro al seno umano da campioni di cellule e tessuti Vasudeva Bhat1,2, Cory Lefebvre1,2, David Goodale1, Mauricio Rodriguez-Torres1,2, Alison L. Allan1,2,3,4 1London Regional Cancer Program, 2Department of Anatomy & Cell Biology, Western University, 3Department of Oncology, Western University, 4Lawson Health Research Institute JoVE 61775 Cancer Research Adattamento del semiautomatico circolanti (CTC) Saggi Tumor Cell per applicazioni cliniche e di ricerca preclinica Lori E. Lowes1,2, Benjamin D. Hedley3, Michael Keeney3,4, Alison L. Allan1,2,4,5 1London Regional Cancer Program, London Health Sciences Centre, 2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, 3Special Hematology/Flow Cytometry, London Health Sciences Centre, 4Lawson Health Research Institute, 5Department of Oncology, Western University JoVE 51248 Medicine
Isolamento e valutazione funzionale di cellule staminali di cancro al seno umano da campioni di cellule e tessuti Vasudeva Bhat1,2, Cory Lefebvre1,2, David Goodale1, Mauricio Rodriguez-Torres1,2, Alison L. Allan1,2,3,4 1London Regional Cancer Program, 2Department of Anatomy & Cell Biology, Western University, 3Department of Oncology, Western University, 4Lawson Health Research Institute JoVE 61775 Cancer Research
Adattamento del semiautomatico circolanti (CTC) Saggi Tumor Cell per applicazioni cliniche e di ricerca preclinica Lori E. Lowes1,2, Benjamin D. Hedley3, Michael Keeney3,4, Alison L. Allan1,2,4,5 1London Regional Cancer Program, London Health Sciences Centre, 2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, 3Special Hematology/Flow Cytometry, London Health Sciences Centre, 4Lawson Health Research Institute, 5Department of Oncology, Western University JoVE 51248 Medicine
