Andre J. van Wijnen

Publications

• Development of an Experimental Animal Model for Lower Back Pain by Percutaneous Injury-Induced Lumbar Facet Joint Osteoarthritis
  Journal of Cellular Physiology. Apr, 2015  |   Pubmed ID: 25858171
• Chromatin Modifiers and Histone Modifications in Bone Formation, Regeneration, and Therapeutic Intervention for Bone-related Disease
  Bone. Mar, 2015  |   Pubmed ID: 25836763
• The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation
  Journal of Cellular Physiology. Mar, 2015  |   Pubmed ID: 25808524
• Runx1 is Associated with Breast Cancer Progression in MMTV-PyMT Transgenic Mice and Its Depletion in Vitro Inhibits Migration and Invasion
  Journal of Cellular Physiology. Mar, 2015  |   Pubmed ID: 25802202
• Efficacy of Intervertebral Disc Regeneration with Stem Cells - A Systematic Review and Meta-analysis of Animal Controlled Trials
  Gene. Mar, 2015  |   Pubmed ID: 25796605
• Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint
  Journal of Cellular Physiology. Feb, 2015  |   Pubmed ID: 25655021
• Targeting of Runx2 by MiR-135 and MiR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
  Cancer Research. Apr, 2015  |   Pubmed ID: 25634212
• Subnuclear Domain Proteins in Cancer Cells Support the Functions of RUNX2 in the DNA Damage Response
  Journal of Cell Science. Feb, 2015  |   Pubmed ID: 25609707
• Intra-renal Delivery of Mesenchymal Stem Cells Attenuates Myocardial Injury After Reversal of Hypertension in Porcine Renovascular Disease
  Stem Cell Research & Therapy. Jan, 2015  |   Pubmed ID: 25599803
• Osteoporosis and Osteoarthritis. Preface
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25493310
• Acute-phase Protein Serum Amyloid A3 is a Novel Paracrine Coupling Factor That Controls Bone Homeostasis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2015  |   Pubmed ID: 25491310
• Biological Strategies for Improved Osseointegration and Osteoinduction of Porous Metal Orthopedic Implants
  Tissue Engineering. Part B, Reviews. Apr, 2015  |   Pubmed ID: 25348836
• MicroRNA-146a Reduces IL-1 Dependent Inflammatory Responses in the Intervertebral Disc
  Gene. Jan, 2015  |   Pubmed ID: 25311550
• Planar Cell Polarity Aligns Osteoblast Division in Response to Substrate Strain
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Mar, 2015  |   Pubmed ID: 25264362
• Histone Deacetylase Inhibition Destabilizes the Multi-potent State of Uncommitted Adipose-derived Mesenchymal Stromal Cells
  Journal of Cellular Physiology. Jan, 2015  |   Pubmed ID: 24912092
• MicroRNA-mediated Survivin Control of Pluripotency
  Journal of Cellular Physiology. Jan, 2015  |   Pubmed ID: 24891298
• Intra-renal Delivery of Mesenchymal Stem Cells and Endothelial Progenitor Cells Attenuates Hypertensive Cardiomyopathy in Experimental Renovascular Hypertension
  Cell Transplantation. Nov, 2014  |   Pubmed ID: 25420012
• A Conserved Interaction That is Essential for the Biogenesis of Histone Locus Bodies
  The Journal of Biological Chemistry. Dec, 2014  |   Pubmed ID: 25339177
• MicroRNA and MRNA Cargo of Extracellular Vesicles from Porcine Adipose Tissue-derived Mesenchymal Stem Cells
  Gene. Nov, 2014  |   Pubmed ID: 25158130
• Hsa-mir-30c Promotes the Invasive Phenotype of Metastatic Breast Cancer Cells by Targeting NOV/CCN3
  Cancer Cell International. 2014  |   Pubmed ID: 25120384
• The Bone-specific Runx2-P1 Promoter Displays Conserved Three-dimensional Chromatin Structure with the Syntenic Supt3h Promoter
  Nucleic Acids Research. 2014  |   Pubmed ID: 25120271
• CBFβ and the Leukemogenic Fusion Protein CBFβ-SMMHC Associate with Mitotic Chromosomes to Epigenetically Regulate Ribosomal Genes
  Journal of Cellular Biochemistry. Dec, 2014  |   Pubmed ID: 25079347
• Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading
  Journal of Cellular Physiology. Jul, 2014  |   Pubmed ID: 25078095
• Runx2 is Required for Early Stages of Endochondral Bone Formation but Delays Final Stages of Bone Repair in Axin2-deficient Mice
  Bone. Sep, 2014  |   Pubmed ID: 24973690
• High-resolution Molecular Validation of Self-renewal and Spontaneous Differentiation in Clinical-grade Adipose-tissue Derived Human Mesenchymal Stem Cells
  Journal of Cellular Biochemistry. Oct, 2014  |   Pubmed ID: 24905804
• Epigenetic Landscape During Osteoblastogenesis Defines a Differentiation-dependent Runx2 Promoter Region
  Gene. Oct, 2014  |   Pubmed ID: 24881813
• Epigenetic Modifications and Canonical Wingless/int-1 Class (WNT) Signaling Enable Trans-differentiation of Nonosteogenic Cells into Osteoblasts
  The Journal of Biological Chemistry. Jul, 2014  |   Pubmed ID: 24867947
• Osteoblasts Protect AML Cells from SDF-1-induced Apoptosis
  Journal of Cellular Biochemistry. Jun, 2014  |   Pubmed ID: 24851270
• Digital Expression Profiling Identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 As Potential Predictive Biomarkers for Neo-adjuvant Chemotherapy Response in Paediatric Osteosarcoma
  PloS One. 2014  |   Pubmed ID: 24835790
• RUNX3 Facilitates Growth of Ewing Sarcoma Cells
  Journal of Cellular Physiology. Dec, 2014  |   Pubmed ID: 24812032
• Fidelity of Histone Gene Regulation is Obligatory for Genome Replication and Stability
  Molecular and Cellular Biology. Jul, 2014  |   Pubmed ID: 24797072
• Genomic Occupancy of Runx2 with Global Expression Profiling Identifies a Novel Dimension to Control of Osteoblastogenesis
  Genome Biology. 2014  |   Pubmed ID: 24655370
• Core Binding Factor β (CBFβ) is Retained in the Midbody During Cytokinesis
  Journal of Cellular Physiology. Oct, 2014  |   Pubmed ID: 24648201
• A Functional N-terminal Domain in C/EBPβ-LAP* is Required for Interacting with SWI/SNF and to Repress Ric-8B Gene Transcription in Osteoblasts
  Journal of Cellular Physiology. Oct, 2014  |   Pubmed ID: 24585571
• Bookmarking Target Genes in Mitosis: a Shared Epigenetic Trait of Phenotypic Transcription Factors and Oncogenes?
  Cancer Research. Jan, 2014  |   Pubmed ID: 24408924
• Heparan Sulfate Proteoglycans and Human Breast Cancer Epithelial Cell Tumorigenicity
  Journal of Cellular Biochemistry. May, 2014  |   Pubmed ID: 24357546
• Pain Assessment in Animal Models of Osteoarthritis
  Gene. Mar, 2014  |   Pubmed ID: 24333346
• The Dynamic Architectural and Epigenetic Nuclear Landscape: Developing the Genomic Almanac of Biology and Disease
  Journal of Cellular Physiology. Jun, 2014  |   Pubmed ID: 24242872
• Gene Wiki Reviews: Marrying Crowdsourcing with Traditional Peer Review
  Gene. Dec, 2013  |   Pubmed ID: 24012870
• Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone H4 Epigenome and Reduces Akt Phosphorylation
  The Journal of Biological Chemistry. Oct, 2013  |   Pubmed ID: 23940046
• FGFR1 Signaling Stimulates Proliferation of Human Mesenchymal Stem Cells by Inhibiting the Cyclin-dependent Kinase Inhibitors P21(Waf1) and P27(Kip1)
  Stem Cells (Dayton, Ohio). Dec, 2013  |   Pubmed ID: 23939995
• The Influence of Collagen and Hyaluronan Matrices on the Delivery and Bioactivity of Bone Morphogenetic Protein-2 and Ectopic Bone Formation
  Acta Biomaterialia. Nov, 2013  |   Pubmed ID: 23871940
• A Current Review of Molecular Mechanisms Regarding Osteoarthritis and Pain
  Gene. Sep, 2013  |   Pubmed ID: 23830938
• A Germline Point Mutation in Runx1 Uncouples Its Role in Definitive Hematopoiesis from Differentiation
  Experimental Hematology. Nov, 2013  |   Pubmed ID: 23823022
• Altered Spinal MicroRNA-146a and the MicroRNA-183 Cluster Contribute to Osteoarthritic Pain in Knee Joints
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2013  |   Pubmed ID: 23744481
• MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor P53 in Osteosarcoma
  The Journal of Biological Chemistry. Jul, 2013  |   Pubmed ID: 23720736
• MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis
  Current Osteoporosis Reports. Jun, 2013  |   Pubmed ID: 23605904
• Targeting Deregulated Epigenetic Control in Cancer
  Journal of Cellular Physiology. Nov, 2013  |   Pubmed ID: 23589100
• Lactoferricin Mediates Anti-inflammatory and Anti-catabolic Effects Via Inhibition of IL-1 and LPS Activity in the Intervertebral Disc
  Journal of Cellular Physiology. Sep, 2013  |   Pubmed ID: 23460134
• Oncogenic Cooperation Between PI3K/Akt Signaling and Transcription Factor Runx2 Promotes the Invasive Properties of Metastatic Breast Cancer Cells
  Journal of Cellular Physiology. Aug, 2013  |   Pubmed ID: 23389849
• Estrogen Receptor α Mediates Proliferation of Osteoblastic Cells Stimulated by Estrogen and Mechanical Strain, but Their Acute Down-regulation of the Wnt Antagonist Sost is Mediated by Estrogen Receptor β
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23362266
• Bovine Lactoferricin Induces TIMP-3 Via the ERK1/2-Sp1 Axis in Human Articular Chondrocytes
  Gene. Mar, 2013  |   Pubmed ID: 23313877
• Runx2 Protein Represses Axin2 Expression in Osteoblasts and is Required for Craniosynostosis in Axin2-deficient Mice
  The Journal of Biological Chemistry. Feb, 2013  |   Pubmed ID: 23300083
• The Cancer-related Transcription Factor Runx2 Modulates Cell Proliferation in Human Osteosarcoma Cell Lines
  Journal of Cellular Physiology. Apr, 2013  |   Pubmed ID: 22949168
• Genomic Occupancy of HLH, AP1 and Runx2 Motifs Within a Nuclease Sensitive Site of the Runx2 Gene
  Journal of Cellular Physiology. Feb, 2013  |   Pubmed ID: 22886425
• Bovine Lactoferricin is Anti-inflammatory and Anti-catabolic in Human Articular Cartilage and Synovium
  Journal of Cellular Physiology. Feb, 2013  |   Pubmed ID: 22740381
• MiR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells
  The Journal of Biological Chemistry. Dec, 2012  |   Pubmed ID: 23060446
• Epigenetic Mechanisms in Leukemia
  Advances in Biological Regulation. Sep, 2012  |   Pubmed ID: 22884030
• Epigenetic Control of Cell Cycle-dependent Histone Gene Expression is a Principal Component of the Abbreviated Pluripotent Cell Cycle
  Molecular and Cellular Biology. Oct, 2012  |   Pubmed ID: 22826438
• Toll-like Receptor Adaptor Signaling Molecule MyD88 on Intervertebral Disk Homeostasis: in Vitro, Ex Vivo Studies
  Gene. Sep, 2012  |   Pubmed ID: 22692007
• Hyaluronic Acid-based Hydrogels Functionalized with Heparin That Support Controlled Release of Bioactive BMP-2
  Biomaterials. Sep, 2012  |   Pubmed ID: 22687758
• Control of Mesenchymal Lineage Progression by MicroRNAs Targeting Skeletal Gene Regulators Trps1 and Runx2
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22544738
• Species-specific Biological Effects of FGF-2 in Articular Cartilage: Implication for Distinct Roles Within the FGF Receptor Family
  Journal of Cellular Biochemistry. Jul, 2012  |   Pubmed ID: 22415882
• A RUNX2-HDAC1 Co-repressor Complex Regulates RRNA Gene Expression by Modulating UBF Acetylation
  Journal of Cell Science. Jun, 2012  |   Pubmed ID: 22393235
• MicroRNA Control of Bone Formation and Homeostasis
  Nature Reviews. Endocrinology. Apr, 2012  |   Pubmed ID: 22290358
• Biological Effects of the Plant-derived Polyphenol Resveratrol in Human Articular Cartilage and Chondrosarcoma Cells
  Journal of Cellular Physiology. Oct, 2012  |   Pubmed ID: 22252971
• Bone Marrow-derived Heparan Sulfate Potentiates the Osteogenic Activity of Bone Morphogenetic Protein-2 (BMP-2)
  Bone. Apr, 2012  |   Pubmed ID: 22227436
• Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes Involved in Cell Adhesion and Motility
  The Journal of Biological Chemistry. Feb, 2012  |   Pubmed ID: 22158627
• Heparan Sulfate Enhances the Self-renewal and Therapeutic Potential of Mesenchymal Stem Cells from Human Adult Bone Marrow
  Stem Cells and Development. Jul, 2012  |   Pubmed ID: 22066689
• Identification of RUNX3 As a Component of the MST/Hpo Signaling Pathway
  Journal of Cellular Physiology. Feb, 2012  |   Pubmed ID: 21678419
• Lactoferricin Mediates Anabolic and Anti-catabolic Effects in the Intervertebral Disc
  Journal of Cellular Physiology. Apr, 2012  |   Pubmed ID: 21678402
• The Rat Intervertebral Disk Degeneration Pain Model: Relationships Between Biological and Structural Alterations and Pain
  Arthritis Research & Therapy. 2011  |   Pubmed ID: 21996269
• Characterization of a New Animal Model for Evaluation and Treatment of Back Pain Due to Lumbar Facet Joint Osteoarthritis
  Arthritis and Rheumatism. Oct, 2011  |   Pubmed ID: 21953085
• The Polypyrimidine/polypurine Motif in the Mouse Mu Opioid Receptor Gene Promoter is a Supercoiling-regulatory Element
  Gene. Nov, 2011  |   Pubmed ID: 21839154
• Fibroblast Growth Factor Receptor 1 is Principally Responsible for Fibroblast Growth Factor 2-induced Catabolic Activities in Human Articular Chondrocytes
  Arthritis Research & Therapy. 2011  |   Pubmed ID: 21835001
• Runx2 Protein Expression Utilizes the Runx2 P1 Promoter to Establish Osteoprogenitor Cell Number for Normal Bone Formation
  The Journal of Biological Chemistry. Aug, 2011  |   Pubmed ID: 21676869
• A Program of MicroRNAs Controls Osteogenic Lineage Progression by Targeting Transcription Factor Runx2
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011  |   Pubmed ID: 21628588
• Functional Coupling of Transcription Factor HiNF-P and Histone H4 Gene Expression During Pre- and Post-natal Mouse Development
  Gene. Sep, 2011  |   Pubmed ID: 21605641
• Epigenetic Regulation of Early Osteogenesis and Mineralized Tissue Formation by a HOXA10-PBX1-associated Complex
  Cells, Tissues, Organs. 2011  |   Pubmed ID: 21597276
• TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts
  PloS One. 2011  |   Pubmed ID: 21559363
• Bookmarking the Genome: Maintenance of Epigenetic Information
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21454629
• MicroRNA-146a is Linked to Pain-related Pathophysiology of Osteoarthritis
  Gene. Jul, 2011  |   Pubmed ID: 21397669
• Osteoarthritic Tissues Modulate Functional Properties of Sensory Neurons Associated with Symptomatic OA Pain
  Molecular Biology Reports. Nov, 2011  |   Pubmed ID: 21327824
• Genome-wide Screening in Human Growth Plates During Puberty in One Patient Suggests a Role for RUNX2 in Epiphyseal Maturation
  The Journal of Endocrinology. May, 2011  |   Pubmed ID: 21307122
• C/EBPβ Binds the P1 Promoter of the Runx2 Gene and Up-regulates Runx2 Transcription in Osteoblastic Cells
  Journal of Cellular Physiology. Nov, 2011  |   Pubmed ID: 21302301
• An Architectural Genetic and Epigenetic Perspective
  Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2011  |   Pubmed ID: 21184003
• Reprogramming the Pluripotent Cell Cycle: Restoration of an Abbreviated G1 Phase in Human Induced Pluripotent Stem (iPS) Cells
  Journal of Cellular Physiology. May, 2011  |   Pubmed ID: 20945438
• Live Cell Imaging of the Cancer-related Transcription Factor RUNX2 During Mitotic Progression
  Journal of Cellular Physiology. May, 2011  |   Pubmed ID: 20945391
• The Histone Deacetylase Inhibitor, Vorinostat, Reduces Tumor Growth at the Metastatic Bone Site and Associated Osteolysis, but Promotes Normal Bone Loss
  Molecular Cancer Therapeutics. Dec, 2010  |   Pubmed ID: 21159607
• Architectural Genetic and Epigenetic Control of Regulatory Networks: Compartmentalizing Machinery for Transcription and Chromatin Remodeling in Nuclear Microenvironments
  Critical Reviews in Eukaryotic Gene Expression. 2010  |   Pubmed ID: 21133844
• Cancer-related Ectopic Expression of the Bone-related Transcription Factor RUNX2 in Non-osseous Metastatic Tumor Cells is Linked to Cell Proliferation and Motility
  Breast Cancer Research : BCR. 2010  |   Pubmed ID: 21029421
• A Network Connecting Runx2, SATB2, and the MiR-23a~27a~24-2 Cluster Regulates the Osteoblast Differentiation Program
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010  |   Pubmed ID: 20980664
• Insulin-like Growth Factor 1 Synergizes with Bone Morphogenetic Protein 7-mediated Anabolism in Bovine Intervertebral Disc Cells
  Arthritis and Rheumatism. Dec, 2010  |   Pubmed ID: 20812336
• Architectural Epigenetics: Mitotic Retention of Mammalian Transcriptional Regulatory Information
  Molecular and Cellular Biology. Oct, 2010  |   Pubmed ID: 20696837
• Subnuclear Localization and Intranuclear Trafficking of Transcription Factors
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20694661
• Mitotic Bookmarking of Genes: a Novel Dimension to Epigenetic Control
  Nature Reviews. Genetics. Aug, 2010  |   Pubmed ID: 20628351
• Ribonucleoprotein Immunoprecipitation (RNP-IP): a Direct in Vivo Analysis of MicroRNA-targets
  Journal of Cellular Biochemistry. Jul, 2010  |   Pubmed ID: 20564179
• Alteration of Sensory Neurons and Spinal Response to an Experimental Osteoarthritis Pain Model
  Arthritis and Rheumatism. Oct, 2010  |   Pubmed ID: 20556813
• Synergism Between Wnt3a and Heparin Enhances Osteogenesis Via a Phosphoinositide 3-kinase/Akt/RUNX2 Pathway
  The Journal of Biological Chemistry. Aug, 2010  |   Pubmed ID: 20547765
• The Human SWI/SNF Complex Associates with RUNX1 to Control Transcription of Hematopoietic Target Genes
  Journal of Cellular Physiology. Nov, 2010  |   Pubmed ID: 20506188
• Pbx1 Represses Osteoblastogenesis by Blocking Hoxa10-mediated Recruitment of Chromatin Remodeling Factors
  Molecular and Cellular Biology. Jul, 2010  |   Pubmed ID: 20439491
• The Gene for Aromatase, a Rate-limiting Enzyme for Local Estrogen Biosynthesis, is a Downstream Target Gene of Runx2 in Skeletal Tissues
  Molecular and Cellular Biology. May, 2010  |   Pubmed ID: 20231365
• The Cleidocranial Dysplasia-related R131G Mutation in the Runt-related Transcription Factor RUNX2 Disrupts Binding to DNA but Not CBF-beta
  Journal of Cellular Biochemistry. May, 2010  |   Pubmed ID: 20225274
• Transcriptional Corepressor TLE1 Functions with Runx2 in Epigenetic Repression of Ribosomal RNA Genes
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20160071
• Glycosaminoglycans Modulate RANKL-induced Osteoclastogenesis
  Journal of Cellular Biochemistry. Apr, 2010  |   Pubmed ID: 20135643
• The Cancer-related Runx2 Protein Enhances Cell Growth and Responses to Androgen and TGFbeta in Prostate Cancer Cells
  Journal of Cellular Biochemistry. Mar, 2010  |   Pubmed ID: 20082326
• Dicer Inactivation in Osteoprogenitor Cells Compromises Fetal Survival and Bone Formation, While Excision in Differentiated Osteoblasts Increases Bone Mass in the Adult Mouse
  Developmental Biology. Apr, 2010  |   Pubmed ID: 20079730
• Definitive Hematopoiesis Requires Runx1 C-terminal-mediated Subnuclear Targeting and Transactivation
  Human Molecular Genetics. Mar, 2010  |   Pubmed ID: 20035012
• Transcription Factor-mediated Epigenetic Regulation of Cell Growth and Phenotype for Biological Control and Cancer
  Advances in Enzyme Regulation. 2010  |   Pubmed ID: 19896493
• Cyclin D2 and the CDK Substrate P220(NPAT) Are Required for Self-renewal of Human Embryonic Stem Cells
  Journal of Cellular Physiology. Feb, 2010  |   Pubmed ID: 19890848
• 1alpha,25-dihydroxy Vitamin D(3) Induces Nuclear Matrix Association of the 1alpha,25-dihydroxy Vitamin D(3) Receptor in Osteoblasts Independently of Its Ability to Bind DNA
  Journal of Cellular Physiology. Feb, 2010  |   Pubmed ID: 19885846
• Human Embryonic Stem Cells Are Pre-mitotically Committed to Self-renewal and Acquire a Lengthened G1 Phase Upon Lineage Programming
  Journal of Cellular Physiology. Jan, 2010  |   Pubmed ID: 19774559
• Bioactive Lipids Lysophosphatidic Acid and Sphingosine 1-phosphate Mediate Breast Cancer Cell Biological Functions Through Distinct Mechanisms
  Oncology Research. 2009  |   Pubmed ID: 20112503
• Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a MiR-24/MKP-7/MAPK Network
  Cancer Research. Nov, 2009  |   Pubmed ID: 19826043
• Runt-related Transcription Factor RUNX3 is a Target of MDM2-mediated Ubiquitination
  Cancer Research. Oct, 2009  |   Pubmed ID: 19808967
• Runx2, P53, and PRB Status As Diagnostic Parameters for Deregulation of Osteoblast Growth and Differentiation in a New Pre-chemotherapeutic Osteosarcoma Cell Line (OS1)
  Journal of Cellular Physiology. Dec, 2009  |   Pubmed ID: 19746444
• Impaired Cell Cycle Regulation of the Osteoblast-related Heterodimeric Transcription Factor Runx2-Cbfbeta in Osteosarcoma Cells
  Journal of Cellular Physiology. Dec, 2009  |   Pubmed ID: 19739101
• Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression
  Cancer Research. Sep, 2009  |   Pubmed ID: 19690135
• The Notch-responsive Transcription Factor Hes-1 Attenuates Osteocalcin Promoter Activity in Osteoblastic Cells
  Journal of Cellular Biochemistry. Oct, 2009  |   Pubmed ID: 19670267
• Positive Association Between Nuclear Runx2 and Oestrogen-progesterone Receptor Gene Expression Characterises a Biological Subtype of Breast Cancer
  European Journal of Cancer (Oxford, England : 1990). Sep, 2009  |   Pubmed ID: 19632824
• The Histone Gene Activator HINFP is a Nonredundant Cyclin E/CDK2 Effector During Early Embryonic Cell Cycles
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009  |   Pubmed ID: 19590016
• SWI/SNF-independent Nuclease Hypersensitivity and an Increased Level of Histone Acetylation at the P1 Promoter Accompany Active Transcription of the Bone Master Gene Runx2
  Biochemistry. Aug, 2009  |   Pubmed ID: 19545172
• Prostate Cancer Regulatory Networks
  Journal of Cellular Biochemistry. Aug, 2009  |   Pubmed ID: 19492418
• The Heparan Sulfate Proteoglycan (HSPG) Glypican-3 Mediates Commitment of MC3T3-E1 Cells Toward Osteogenesis
  Journal of Cellular Physiology. Sep, 2009  |   Pubmed ID: 19479939
• Survival Responses of Human Embryonic Stem Cells to DNA Damage
  Journal of Cellular Physiology. Sep, 2009  |   Pubmed ID: 19373864
• The Osteogenic Transcription Factor Runx2 Controls Genes Involved in Sterol/steroid Metabolism, Including CYP11A1 in Osteoblasts
  Molecular Endocrinology (Baltimore, Md.). Jun, 2009  |   Pubmed ID: 19342447
• Biological Functions of MiR-29b Contribute to Positive Regulation of Osteoblast Differentiation
  The Journal of Biological Chemistry. Jun, 2009  |   Pubmed ID: 19342382
• The Subnuclear Organization of Histone Gene Regulatory Proteins and 3' End Processing Factors of Normal Somatic and Embryonic Stem Cells is Compromised in Selected Human Cancer Cell Types
  Journal of Cellular Physiology. Jul, 2009  |   Pubmed ID: 19277982
• The Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/proteoglycan Signaling Axis in Osteoblasts
  Journal of Cellular Biochemistry. May, 2009  |   Pubmed ID: 19259985
• Organization, Integration, and Assembly of Genetic and Epigenetic Regulatory Machinery in Nuclear Microenvironments: Implications for Biological Control in Cancer
  Annals of the New York Academy of Sciences. Feb, 2009  |   Pubmed ID: 19250187
• Transcription-factor-mediated Epigenetic Control of Cell Fate and Lineage Commitment
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Feb, 2009  |   Pubmed ID: 19234518
• Prostaglandin E2 and Its Cognate EP Receptors Control Human Adult Articular Cartilage Homeostasis and Are Linked to the Pathophysiology of Osteoarthritis
  Arthritis and Rheumatism. Feb, 2009  |   Pubmed ID: 19180509
• CDK Inhibitors Selectively Diminish Cell Cycle Controlled Activation of the Histone H4 Gene Promoter by P220NPAT and HiNF-P
  Journal of Cellular Physiology. May, 2009  |   Pubmed ID: 19170105
• A Runx2 Threshold for the Cleidocranial Dysplasia Phenotype
  Human Molecular Genetics. Feb, 2009  |   Pubmed ID: 19028669
• Co-stimulation of the Bone-related Runx2 P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)
  The Journal of Biological Chemistry. Jan, 2009  |   Pubmed ID: 19017640
• Subnuclear Targeting of the Runx3 Tumor Suppressor and Its Epigenetic Association with Mitotic Chromosomes
  Journal of Cellular Physiology. Mar, 2009  |   Pubmed ID: 19006109
• Elevated Expression of Runx2 As a Key Parameter in the Etiology of Osteosarcoma
  Molecular Biology Reports. Jan, 2009  |   Pubmed ID: 18931939
• Specific Residues of RUNX2 Are Obligatory for Formation of BMP2-induced RUNX2-SMAD Complex to Promote Osteoblast Differentiation
  Cells, Tissues, Organs. 2009  |   Pubmed ID: 18728344
• Molecular Switches Involving Homeodomain Proteins, HOXA10 and RUNX2 Regulate Osteoblastogenesis
  Cells, Tissues, Organs. 2009  |   Pubmed ID: 18701816
• The Leukemogenic T(8;21) Fusion Protein AML1-ETO Controls RRNA Genes and Associates with Nucleolar-organizing Regions at Mitotic Chromosomes
  Journal of Cell Science. Dec, 2008  |   Pubmed ID: 19001502
• Staged Assembly of Histone Gene Expression Machinery at Subnuclear Foci in the Abbreviated Cell Cycle of Human Embryonic Stem Cells
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008  |   Pubmed ID: 18957539
• The Histone Gene Cell Cycle Regulator HiNF-P is a Unique Zinc Finger Transcription Factor with a Novel Conserved Auxiliary DNA-binding Motif
  Biochemistry. Nov, 2008  |   Pubmed ID: 18850719
• Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
  Cancer Research. Oct, 2008  |   Pubmed ID: 18829534
• A MicroRNA Signature for a BMP2-induced Osteoblast Lineage Commitment Program
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008  |   Pubmed ID: 18784367
• Intricate Gene Regulatory Networks of Helix-loop-helix (HLH) Proteins Support Regulation of Bone-tissue Related Genes During Osteoblast Differentiation
  Journal of Cellular Biochemistry. Oct, 2008  |   Pubmed ID: 18655182
• Expression of Runx2 Transcription Factor in Non-skeletal Tissues, Sperm and Brain
  Journal of Cellular Physiology. Nov, 2008  |   Pubmed ID: 18636555
• Runx2 Regulates G Protein-coupled Signaling Pathways to Control Growth of Osteoblast Progenitors
  The Journal of Biological Chemistry. Oct, 2008  |   Pubmed ID: 18625716
• Genetic and Epigenetic Regulation in Nuclear Microenvironments for Biological Control in Cancer
  Journal of Cellular Biochemistry. Aug, 2008  |   Pubmed ID: 18615590
• In Situ Nuclear Organization of Regulatory Machinery
  Methods in Molecular Biology (Clifton, N.J.). 2008  |   Pubmed ID: 18463823
• Chromatin Immunoprecipitation Assays: Application of ChIP-on-chip for Defining Dynamic Transcriptional Mechanisms in Bone Cells
  Methods in Molecular Biology (Clifton, N.J.). 2008  |   Pubmed ID: 18463819
• Phenotypic Transcription Factors Epigenetically Mediate Cell Growth Control
  Proceedings of the National Academy of Sciences of the United States of America. May, 2008  |   Pubmed ID: 18445650
• MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival
  Cancer Research. Apr, 2008  |   Pubmed ID: 18413744
• Vitamin D Control of Gene Expression: Temporal and Spatial Parameters for Organization of the Regulatory Machinery
  Critical Reviews in Eukaryotic Gene Expression. 2008  |   Pubmed ID: 18304030
• Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal
  The Journal of Biological Chemistry. Mar, 2008  |   Pubmed ID: 18204048
• P68 (Ddx5) Interacts with Runx2 and Regulates Osteoblast Differentiation
  Journal of Cellular Biochemistry. Apr, 2008  |   Pubmed ID: 17960593
• 1alpha,25-dihydroxy Vitamin D3-enhanced Expression of the Osteocalcin Gene Involves Increased Promoter Occupancy of Basal Transcription Regulators and Gradual Recruitment of the 1alpha,25-dihydroxy Vitamin D3 Receptor-SRC-1 Coactivator Complex
  Journal of Cellular Physiology. Mar, 2008  |   Pubmed ID: 17786964
• Runx2 Deficiency and Defective Subnuclear Targeting Bypass Senescence to Promote Immortalization and Tumorigenic Potential
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007  |   Pubmed ID: 18077419
• The HiNF-P/p220NPAT Cell Cycle Signaling Pathway Controls Nonhistone Target Genes
  Cancer Research. Nov, 2007  |   Pubmed ID: 17974976
• Cell Cycle Related Modulations in Runx2 Protein Levels Are Independent of Lymphocyte Enhancer-binding Factor 1 (Lef1) in Proliferating Osteoblasts
  Journal of Molecular Histology. Oct, 2007  |   Pubmed ID: 17885813
• Transcriptional Activation of the Histone Nuclear Factor P (HiNF-P) Gene by HiNF-P and Its Cyclin E/CDK2 Responsive Co-factor P220NPAT Defines a Novel Autoregulatory Loop at the G1/S Phase Transition
  Gene. Nov, 2007  |   Pubmed ID: 17826007
• Basic Fibroblast Growth Factor Activates the MAPK and NFkappaB Pathways That Converge on Elk-1 to Control Production of Matrix Metalloproteinase-13 by Human Adult Articular Chondrocytes
  The Journal of Biological Chemistry. Oct, 2007  |   Pubmed ID: 17724016
• Nucleosome Organization and Targeting of SWI/SNF Chromatin-remodeling Complexes: Contributions of the DNA Sequence
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2007  |   Pubmed ID: 17713577
• The Interactome of the Histone Gene Regulatory Factor HiNF-P Suggests Novel Cell Cycle Related Roles in Transcriptional Control and RNA Processing
  Journal of Cellular Biochemistry. Sep, 2007  |   Pubmed ID: 17577209
• Cell Cycle Dependent Phosphorylation and Subnuclear Organization of the Histone Gene Regulator P220(NPAT) in Human Embryonic Stem Cells
  Journal of Cellular Physiology. Oct, 2007  |   Pubmed ID: 17520687
• Cooperation Between P27 and P107 During Endochondral Ossification Suggests a Genetic Pathway Controlled by P27 and P130
  Molecular and Cellular Biology. Jul, 2007  |   Pubmed ID: 17502351
• Organization of Transcriptional Regulatory Machinery in Nuclear Microenvironments: Implications for Biological Control and Cancer
  Advances in Enzyme Regulation. 2007  |   Pubmed ID: 17363043
• Mitotic Retention of Gene Expression Patterns by the Cell Fate-determining Transcription Factor Runx2
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007  |   Pubmed ID: 17360627
• HOXA10 Controls Osteoblastogenesis by Directly Activating Bone Regulatory and Phenotypic Genes
  Molecular and Cellular Biology. May, 2007  |   Pubmed ID: 17325044
• Basic Fibroblast Growth Factor Stimulates Matrix Metalloproteinase-13 Via the Molecular Cross-talk Between the Mitogen-activated Protein Kinases and Protein Kinase Cdelta Pathways in Human Adult Articular Chondrocytes
  The Journal of Biological Chemistry. Apr, 2007  |   Pubmed ID: 17311929
• An Architectural Perspective of Vitamin D Responsiveness
  Archives of Biochemistry and Biophysics. Apr, 2007  |   Pubmed ID: 17288986
• Chromatin Remodeling by SWI/SNF Results in Nucleosome Mobilization to Preferential Positions in the Rat Osteocalcin Gene Promoter
  The Journal of Biological Chemistry. Mar, 2007  |   Pubmed ID: 17272279
• Mitotic Occupancy and Lineage-specific Transcriptional Control of RRNA Genes by Runx2
  Nature. Jan, 2007  |   Pubmed ID: 17251981
• The 1alpha,25-dihydroxy Vitamin D3 Receptor Preferentially Recruits the Coactivator SRC-1 During Up-regulation of the Osteocalcin Gene
  The Journal of Steroid Biochemistry and Molecular Biology. Mar, 2007  |   Pubmed ID: 17218095
• Mitotic Control of RUNX2 Phosphorylation by Both CDK1/cyclin B Kinase and PP1/PP2A Phosphatase in Osteoblastic Cells
  Journal of Cellular Biochemistry. Apr, 2007  |   Pubmed ID: 17171635
• HiNF-P is a Bifunctional Regulator of Cell Cycle Controlled Histone H4 Gene Transcription
  Journal of Cellular Biochemistry. May, 2007  |   Pubmed ID: 17163457
• Establishment of Histone Gene Regulation and Cell Cycle Checkpoint Control in Human Embryonic Stem Cells
  Journal of Cellular Physiology. Feb, 2007  |   Pubmed ID: 17096384
• Heparan Sulfate Regulates the Anabolic Activity of MC3T3-E1 Preosteoblast Cells by Induction of Runx2
  Journal of Cellular Physiology. Jan, 2007  |   Pubmed ID: 17051597
• Reconstitution of Runx2/Cbfa1-null Cells Identifies a Requirement for BMP2 Signaling Through a Runx2 Functional Domain During Osteoblast Differentiation
  Journal of Cellular Biochemistry. Feb, 2007  |   Pubmed ID: 16927309
• The Histone Gene Transcription Factor HiNF-P Stabilizes Its Cell Cycle Regulatory Co-activator P220NPAT
  Biochemistry. Dec, 2006  |   Pubmed ID: 17176114
• BMP2 Commitment to the Osteogenic Lineage Involves Activation of Runx2 by DLX3 and a Homeodomain Transcriptional Network
  The Journal of Biological Chemistry. Dec, 2006  |   Pubmed ID: 17060321
• Networks and Hubs for the Transcriptional Control of Osteoblastogenesis
  Reviews in Endocrine & Metabolic Disorders. Jun, 2006  |   Pubmed ID: 17051438
• An Architectural Perspective of Cell-cycle Control at the G1/S Phase Cell-cycle Transition
  Journal of Cellular Physiology. Dec, 2006  |   Pubmed ID: 17001681
• Alterations in Intranuclear Localization of Runx2 Affect Biological Activity
  Journal of Cellular Physiology. Dec, 2006  |   Pubmed ID: 16972259
• Self-renewal of Human Embryonic Stem Cells is Supported by a Shortened G1 Cell Cycle Phase
  Journal of Cellular Physiology. Dec, 2006  |   Pubmed ID: 16972248
• Sulfated Glycosaminoglycans Mediate the Effects of FGF2 on the Osteogenic Potential of Rat Calvarial Osteoprogenitor Cells
  Journal of Cellular Physiology. Dec, 2006  |   Pubmed ID: 16972247
• Chromatin Remodeling and Transcriptional Activity of the Bone-specific Osteocalcin Gene Require CCAAT/enhancer-binding Protein Beta-dependent Recruitment of SWI/SNF Activity
  The Journal of Biological Chemistry. Aug, 2006  |   Pubmed ID: 16772287
• VRK1 Signaling Pathway in the Context of the Proliferation Phenotype in Head and Neck Squamous Cell Carcinoma
  Molecular Cancer Research : MCR. Mar, 2006  |   Pubmed ID: 16547155
• The Bone-related Zn Finger Transcription Factor Osterix Promotes Proliferation of Mesenchymal Cells
  Gene. Jan, 2006  |   Pubmed ID: 16314050
• Four Novel RUNX2 Mutations Including a Splice Donor Site Result in the Cleidocranial Dysplasia Phenotype
  Journal of Cellular Physiology. Apr, 2006  |   Pubmed ID: 16270353
• Lymphocyte Enhancer-binding Factor 1 (Lef1) Inhibits Terminal Differentiation of Osteoblasts
  Journal of Cellular Biochemistry. Apr, 2006  |   Pubmed ID: 16267835
• Microtubule-dependent Nuclear-cytoplasmic Shuttling of Runx2
  Journal of Cellular Physiology. Feb, 2006  |   Pubmed ID: 16110492
• Brg1, the ATPase Subunit of the SWI/SNF Chromatin Remodeling Complex, is Required for Myeloid Differentiation to Granulocytes
  Journal of Cellular Physiology. Jan, 2006  |   Pubmed ID: 15965950
• The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion
  Molecular and Cellular Biology. Oct, 2005  |   Pubmed ID: 16166639
• Subnuclear Targeting of Runx1 is Required for Synergistic Activation of the Myeloid Specific M-CSF Receptor Promoter by PU.1
  Journal of Cellular Biochemistry. Nov, 2005  |   Pubmed ID: 16149049
• Combinatorial Organization of the Transcriptional Regulatory Machinery in Biological Control and Cancer
  Advances in Enzyme Regulation. 2005  |   Pubmed ID: 16135382
• Coordinate Control and Selective Expression of the Full Complement of Replication-dependent Histone H4 Genes in Normal and Cancer Cells
  The Journal of Biological Chemistry. Nov, 2005  |   Pubmed ID: 16131487
• Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression
  The Journal of Biological Chemistry. Sep, 2005  |   Pubmed ID: 16043491
• HiNF-P Directly Links the Cyclin E/CDK2/p220NPAT Pathway to Histone H4 Gene Regulation at the G1/S Phase Cell Cycle Transition
  Molecular and Cellular Biology. Jul, 2005  |   Pubmed ID: 15988025
• Point Mutation in AML1 Disrupts Subnuclear Targeting, Prevents Myeloid Differentiation, and Effects a Transformation-like Phenotype
  Proceedings of the National Academy of Sciences of the United States of America. May, 2005  |   Pubmed ID: 15870195
• Organization of Transcriptional Regulatory Machinery in Osteoclast Nuclei: Compartmentalization of Runx1
  Journal of Cellular Physiology. Sep, 2005  |   Pubmed ID: 15828028