Anne Osbourn

Publications

• Sea Cucumber Genome Provides Insights into Saponin Biosynthesis and Aestivation Regulation
  Cell Discovery. 2018  |   Pubmed ID: 29951224
• Multigenome Analysis Implicates Miniature Inverted-repeat Transposable Elements (MITEs) in Metabolic Diversification in Eudicots
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2018  |   Pubmed ID: 29941591
• Engineering Terpenoid Production Through Transient Expression in Nicotiana Benthamiana
  Plant Cell Reports. May, 2018  |   Pubmed ID: 29786761
• Identification of Key Amino Acid Residues Determining Product Specificity of 2,3-oxidosqualene Cyclase in Oryza Species
  The New Phytologist. May, 2018  |   Pubmed ID: 29528490
• Triterpene Messages from the EU-FP7 Project TriForC
  Trends in Plant Science. Apr, 2018  |   Pubmed ID: 29483042
• Diverged Plant Terpene Synthases Reroute the Carbocation Cyclization Path Towards the Formation of Unprecedented 6/11/5 and 6/6/7/5 Sesterterpene Scaffolds
  Angewandte Chemie (International Ed. in English). Jan, 2018  |   Pubmed ID: 29194888
• Can Human Experts Predict Solubility Better Than Computers?
  Journal of Cheminformatics. Dec, 2017  |   Pubmed ID: 29238891
• Painting with Betalains
  Nature Plants. Nov, 2017  |   Pubmed ID: 29116231
• A Translational Synthetic Biology Platform for Rapid Access to Gram-scale Quantities of Novel Drug-like Molecules
  Metabolic Engineering. 07, 2017  |   Pubmed ID: 28687337
• Unearthing a Sesterterpene Biosynthetic Repertoire in the Brassicaceae Through Genome Mining Reveals Convergent Evolution
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2017  |   Pubmed ID: 28673978
• Harnessing Plant Metabolic Diversity
  Current Opinion in Chemical Biology. Oct, 2017  |   Pubmed ID: 28527344
• PlantiSMASH: Automated Identification, Annotation and Expression Analysis of Plant Biosynthetic Gene Clusters
  Nucleic Acids Research. Jul, 2017  |   Pubmed ID: 28453650
• Convergence and Divergence of Bitterness Biosynthesis and Regulation in Cucurbitaceae
  Nature Plants. 11, 2016  |   Pubmed ID: 27892922
• A Conserved Amino Acid Residue Critical for Product and Substrate Specificity in Plant Triterpene Synthases
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2016  |   Pubmed ID: 27412861
• Computational Genomic Identification and Functional Reconstitution of Plant Natural Product Biosynthetic Pathways
  Natural Product Reports. Aug, 2016  |   Pubmed ID: 27321668
• Plant Metabolic Clusters - from Genetics to Genomics
  The New Phytologist. 08, 2016  |   Pubmed ID: 27112429
• Delineation of Metabolic Gene Clusters in Plant Genomes by Chromatin Signatures
  Nucleic Acids Research. Mar, 2016  |   Pubmed ID: 26895889
• Editorial Overview: Plant Biotechnology
  Current Opinion in Biotechnology. Feb, 2016  |   Pubmed ID: 26730719
• Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea Europaea) Fruits
  The Journal of Biological Chemistry. Mar, 2016  |   Pubmed ID: 26709230
• Minimum Information About a Biosynthetic Gene Cluster
  Nature Chemical Biology. Sep, 2015  |   Pubmed ID: 26284661
• Standards for Plant Synthetic Biology: a Common Syntax for Exchange of DNA Parts
  The New Phytologist. Oct, 2015  |   Pubmed ID: 26171760
• MYB Transcription Factors As Regulators of Phenylpropanoid Metabolism in Plants
  Molecular Plant. May, 2015  |   Pubmed ID: 25840349
• OSC2 and CYP716A14v2 Catalyze the Biosynthesis of Triterpenoids for the Cuticle of Aerial Organs of Artemisia Annua
  The Plant Cell. Jan, 2015  |   Pubmed ID: 25576188
• Temporal Transcriptome Changes Induced by Methyl Jasmonate in Salvia Sclarea
  Gene. Mar, 2015  |   Pubmed ID: 25536164
• Investigation of Terpene Diversification Across Multiple Sequenced Plant Genomes
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015  |   Pubmed ID: 25502595
• Regulation of Metabolic Gene Clusters in Arabidopsis Thaliana
  The New Phytologist. Jan, 2015  |   Pubmed ID: 25417931
• Metabolic and Functional Diversity of Saponins, Biosynthetic Intermediates and Semi-synthetic Derivatives
  Critical Reviews in Biochemistry and Molecular Biology. Nov-Dec, 2014  |   Pubmed ID: 25286183
• Key Applications of Plant Metabolic Engineering
  PLoS Biology. Jun, 2014  |   Pubmed ID: 24915445
• Investigation of Triterpene Synthesis and Regulation in Oats Reveals a Role for β-amyrin in Determining Root Epidermal Cell Patterning
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014  |   Pubmed ID: 24912185
• Gene Clustering in Plant Specialized Metabolism
  Current Opinion in Biotechnology. Apr, 2014  |   Pubmed ID: 24679264
• Triterpene Biosynthesis in Plants
  Annual Review of Plant Biology. 2014  |   Pubmed ID: 24498976
• Rapid Metabolic Pathway Assembly and Modification Using Serine Integrase Site-specific Recombination
  Nucleic Acids Research. Feb, 2014  |   Pubmed ID: 24225316
• Biochemical Analysis of a Multifunctional Cytochrome P450 (CYP51) Enzyme Required for Synthesis of Antimicrobial Triterpenes in Plants
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013  |   Pubmed ID: 23940321
• Comparative Metatranscriptomics Reveals Kingdom Level Changes in the Rhizosphere Microbiome of Plants
  The ISME Journal. Dec, 2013  |   Pubmed ID: 23864127
• A One-pot Enzymatic Approach to the O-fluoroglucoside of N-methylanthranilate
  Bioorganic & Medicinal Chemistry. Aug, 2013  |   Pubmed ID: 23806835
• Modularity of Plant Metabolic Gene Clusters: a Trio of Linked Genes That Are Collectively Required for Acylation of Triterpenes in Oat
  The Plant Cell. Mar, 2013  |   Pubmed ID: 23532069
• Glycosyltransferases from Oat (Avena) Implicated in the Acylation of Avenacins
  The Journal of Biological Chemistry. Feb, 2013  |   Pubmed ID: 23258535
• Finding and Analyzing Plant Metabolic Gene Clusters
  Methods in Enzymology. 2012  |   Pubmed ID: 23084936
• Synthetic Biology. 4th New Phytologist Workshop, Bristol, UK, June 2012
  The New Phytologist. Nov, 2012  |   Pubmed ID: 23043589
• Order in the Playground: Formation of Plant Gene Clusters in Dynamic Chromosomal Regions
  Mobile Genetic Elements. Jan, 2012  |   Pubmed ID: 22754752
• Formation of Plant Metabolic Gene Clusters Within Dynamic Chromosomal Regions
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011  |   Pubmed ID: 21876149
• The Saponins: Polar Isoprenoids with Important and Diverse Biological Activities
  Natural Product Reports. Jul, 2011  |   Pubmed ID: 21584304
• Investigation of the Potential for Triterpene Synthesis in Rice Through Genome Mining and Metabolic Engineering
  The New Phytologist. Jul, 2011  |   Pubmed ID: 21501172
• From Hormones to Secondary Metabolism: the Emergence of Metabolic Gene Clusters in Plants
  The Plant Journal : for Cell and Molecular Biology. Apr, 2011  |   Pubmed ID: 21443624
• Gene Clusters for Secondary Metabolic Pathways: an Emerging Theme in Plant Biology
  Plant Physiology. Oct, 2010  |   Pubmed ID: 20921179
• Secondary Metabolic Gene Clusters: Evolutionary Toolkits for Chemical Innovation
  Trends in Genetics : TIG. Oct, 2010  |   Pubmed ID: 20739089
• Common Genetic Pathways Regulate Organ-specific Infection-related Development in the Rice Blast Fungus
  The Plant Cell. Mar, 2010  |   Pubmed ID: 20348434
• Evolution of Serine Carboxypeptidase-like Acyltransferases in the Monocots
  Plant Signaling & Behavior. Feb, 2010  |   Pubmed ID: 20173416
• Cell Type-specific Chromatin Decondensation of a Metabolic Gene Cluster in Oats
  The Plant Cell. Dec, 2009  |   Pubmed ID: 20040536
• A Serine Carboxypeptidase-like Acyltransferase is Required for Synthesis of Antimicrobial Compounds and Disease Resistance in Oats
  The Plant Cell. Aug, 2009  |   Pubmed ID: 19684243
• Operons
  Cellular and Molecular Life Sciences : CMLS. Dec, 2009  |   Pubmed ID: 19662496
• SAW: Breaking Down Barriers Between Art and Science
  PLoS Biology. Aug, 2008  |   Pubmed ID: 18752351
• Metabolic Diversification--independent Assembly of Operon-like Gene Clusters in Different Plants
  Science (New York, N.Y.). Apr, 2008  |   Pubmed ID: 18356490
• Sad3 and Sad4 Are Required for Saponin Biosynthesis and Root Development in Oat
  The Plant Cell. Jan, 2008  |   Pubmed ID: 18203919
• A Different Function for a Member of an Ancient and Highly Conserved Cytochrome P450 Family: from Essential Sterols to Plant Defense
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006  |   Pubmed ID: 17124172
• First Encounters--deployment of Defence-related Natural Products by Plants
  The New Phytologist. 2006  |   Pubmed ID: 16995908
• Dual Effects of Plant Steroidal Alkaloids on Saccharomyces Cerevisiae
  Antimicrobial Agents and Chemotherapy. Aug, 2006  |   Pubmed ID: 16870766
• The Poetry of Science
  Nature Reviews. Microbiology. 01, 2006  |   Pubmed ID: 16357863
• Comparative Transcriptomics of Rice Reveals an Ancient Pattern of Response to Microbial Colonization
  Proceedings of the National Academy of Sciences of the United States of America. May, 2005  |   Pubmed ID: 15905328
• Unravelling Triterpene Glycoside Synthesis in Plants: Phytochemistry and Functional Genomics Join Forces
  Planta. Feb, 2005  |   Pubmed ID: 15703926
• 2003 Asilomar Meeting Report
  Fungal Genetics and Biology : FG & B. Feb, 2004  |   Pubmed ID: 14732257
• Molecular Cloning and Characterization of Triterpene Synthases from Medicago Truncatula and Lotus Japonicus
  Plant Molecular Biology. Mar, 2003  |   Pubmed ID: 12683345
• Saponins in Cereals
  Phytochemistry. Jan, 2003  |   Pubmed ID: 12475612
• Biosynthesis of Triterpenoid Saponins in Plants
  Advances in Biochemical Engineering/biotechnology. 2002  |   Pubmed ID: 11783842
• Tox-boxes, Fungal Secondary Metabolites, and Plant Disease
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2001  |   Pubmed ID: 11734635
• L-RCA (ligation-rolling Circle Amplification): a General Method for Genotyping of Single Nucleotide Polymorphisms (SNPs)
  Nucleic Acids Research. Nov, 2001  |   Pubmed ID: 11713336
• Fungal Resistance to Plant Antibiotics As a Mechanism of Pathogenesis
  Microbiology and Molecular Biology Reviews : MMBR. Sep, 1999  |   Pubmed ID: 10477313
• Isolation, Characterization, and Avenacin Sensitivity of a Diverse Collection of Cereal-root-colonizing Fungi
  Applied and Environmental Microbiology. Aug, 1999  |   Pubmed ID: 10427021