Anthony Lang Division of Neurology, Department of Medicine University of Toronto Biography Publications Institution JoVE Articles Anthony Lang has not added a biography. If you are Anthony Lang and would like to personalize this page please email our Author Liaison for assistance. Publications Oculogyric Crises in PLA2G6 Associated Neurodegeneration Parkinsonism & Related Disorders. Mar, 2018 | Pubmed ID: 29574084 Functional Neurological Disorders in Parkinson Disease Journal of Neurology, Neurosurgery, and Psychiatry. Mar, 2018 | Pubmed ID: 29549192 Actigraphy Detects Greater Intra-Individual Variability During Gait in Non-Manifesting LRRK2 Mutation Carriers Journal of Parkinson's Disease. 2018 | Pubmed ID: 29480219 Pallidal Deep Brain Stimulation Modulates Cortical Excitability and Plasticity Annals of Neurology. Feb, 2018 | Pubmed ID: 29369401 Exacerbation of Psychosis Triggered by a Synthetic Cannabinoid in a 70-year-old Woman with Parkinson Disease CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. Jan, 2018 | Pubmed ID: 29335263 What is "essential" About Essential Tremor? A Diagnostic Placeholder Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2018 | Pubmed ID: 29272067 Lymphatic Vasculature in Human Dural Superior Sagittal Sinus: Implications for Neurodegenerative Proteinopathies Neuroscience Letters. Feb, 2018 | Pubmed ID: 29133178 Impaired Emotion Processing in Functional (psychogenic) Tremor: A Functional Magnetic Resonance Imaging Study NeuroImage. Clinical. 2018 | Pubmed ID: 29085776 Altered Gut Microbiome and Metabolome in Patients with Multiple System Atrophy Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2018 | Pubmed ID: 29083071 [F]AV-1451 Binding to Neuromelanin in the Substantia Nigra in PD and PSP Brain Structure & Function. Mar, 2018 | Pubmed ID: 28884232 [F]-THK5351 PET Correlates with Topology and Symptom Severity in Progressive Supranuclear Palsy Frontiers in Aging Neuroscience. 2017 | Pubmed ID: 29387005 Asymmetric Neuromodulation of Motor Circuits in Parkinson's Disease: The Role of Subthalamic Deep Brain Stimulation Surgical Neurology International. 2017 | Pubmed ID: 29184712 Is There Even Such a Thing As "idiopathic Normal Pressure Hydrocephalus"? Annals of Neurology. Dec, 2017 | Pubmed ID: 29136297 Deconstructing Normal Pressure Hydrocephalus: Ventriculomegaly As Early Sign of Neurodegeneration Annals of Neurology. Oct, 2017 | Pubmed ID: 28892572 Alcohol Improves Cerebellar Learning Deficit in Myoclonus-dystonia: A Clinical and Electrophysiological Investigation Annals of Neurology. Oct, 2017 | Pubmed ID: 28869676 Progressive Ataxia and Palatal Tremor: Two Autopsy Cases of a Novel Tauopathy Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2017 | Pubmed ID: 28736850 Motor Phenotype in Neurodegenerative Disorders: Gait and Balance Platform Study Design Protocol for the Ontario Neurodegenerative Research Initiative (ONDRI) Journal of Alzheimer's Disease : JAD. 2017 | Pubmed ID: 28671116 Advances in Progressive Supranuclear Palsy: New Diagnostic Criteria, Biomarkers, and Therapeutic Approaches The Lancet. Neurology. Jul, 2017 | Pubmed ID: 28653647 Whole-genome Sequencing Suggests Mechanisms for 22q11.2 Deletion-associated Parkinson's Disease PloS One. 2017 | Pubmed ID: 28430790 Neuroimaging and Clinical Features in Adults with a 22q11.2 Deletion at Risk of Parkinson's Disease Brain : a Journal of Neurology. May, 2017 | Pubmed ID: 28369257 Imaging Biomarkers in Parkinson's Disease and Parkinsonian Syndromes: Current and Emerging Concepts Translational Neurodegeneration. 2017 | Pubmed ID: 28360997 Parkinson Disease Nature Reviews. Disease Primers. Mar, 2017 | Pubmed ID: 28332488 Biomarker-driven Phenotyping in Parkinson's Disease: A Translational Missing Link in Disease-modifying Clinical Trials Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2017 | Pubmed ID: 28233927 Oculogyric Crises: A Review of Phenomenology, Etiology, Pathogenesis, and Treatment Movement Disorders : Official Journal of the Movement Disorder Society. Feb, 2017 | Pubmed ID: 28218460 Peduncolopontine Nucleus Stimulation in Progressive Supranuclear Palsy: a Randomised Trial Journal of Neurology, Neurosurgery, and Psychiatry. Jul, 2017 | Pubmed ID: 28214797 Adult Motor Phenotype Differentiates Dravet Syndrome from Lennox-Gastaut Syndrome and Links SCN1A to Early Onset Parkinsonian Features Epilepsia. 03, 2017 | Pubmed ID: 28186331 Positron Emission Tomography Imaging of Tau Pathology in Progressive Supranuclear Palsy Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2017 | Pubmed ID: 28155586 AAV1/2-induced Overexpression of A53T-α-synuclein in the Substantia Nigra Results in Degeneration of the Nigrostriatal System with Lewy-like Pathology and Motor Impairment: a New Mouse Model for Parkinson's Disease Acta Neuropathologica Communications. Feb, 2017 | Pubmed ID: 28143577 Tracking the Course of Prodromal Parkinson's Disease Brain : a Journal of Neurology. 02, 2017 | Pubmed ID: 28137955 Essential Pitfalls in "essential" Tremor Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2017 | Pubmed ID: 28116753 Precision Medicine for Disease Modification in Parkinson Disease Nature Reviews. Neurology. Feb, 2017 | Pubmed ID: 28106064 Heart Rate Variability in Leucine-rich Repeat Kinase 2-associated Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2017 | Pubmed ID: 28071824 Basal Ganglia Calcification in a Case of PKAN Parkinsonism & Related Disorders. Mar, 2017 | Pubmed ID: 28024710 Fatigue in Parkinson's Disease: The Contribution of Cerebral Metabolic Changes Human Brain Mapping. 01, 2017 | Pubmed ID: 27571419 Alternating Hemiplegia of Childhood As a New Presentation of Adenylate Cyclase 5-Mutation-Associated Disease: A Report of Two Cases The Journal of Pediatrics. Dec, 2016 | Pubmed ID: 27931826 Disrupted Nodal and Hub Organization Account for Brain Network Abnormalities in Parkinson's Disease Frontiers in Aging Neuroscience. 2016 | Pubmed ID: 27891090 α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era Trends in Neurosciences. 11, 2016 | Pubmed ID: 27776749 Reply Letter to Jinnah "Locus Pocus" and Albanese "Complex Dystonia is Not a Category in the New 2013 Consensus Classification": Necessary Evolution, No Magic! Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2016 | Pubmed ID: 27619077 'Under Pressure': is There a Link Between Orthostatic Hypotension and Cognitive Impairment in α-synucleinopathies? Journal of Neurology, Neurosurgery, and Psychiatry. 12, 2016 | Pubmed ID: 27613160 Neurogenic Orthostatic Hypotension and Supine Hypertension in Parkinson's Disease and Related Synucleinopathies: Prioritisation of Treatment Targets The Lancet. Neurology. Aug, 2016 | Pubmed ID: 27478953 Long-term Double-blinded Unilateral Pedunculopontine Area Stimulation in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. 10, 2016 | Pubmed ID: 27392513 A Novel KCNA1 Mutation in a Family with Episodic Ataxia and Malignant Hyperthermia Neurogenetics. 10, 2016 | Pubmed ID: 27271339 Appendectomy in Mid and Later Life and Risk of Parkinson's Disease: A Population-based Study Movement Disorders : Official Journal of the Movement Disorder Society. 08, 2016 | Pubmed ID: 27241338 Dopamine D2 Receptor Gene Variants and Response to Rasagiline in Early Parkinson's Disease: a Pharmacogenetic Study Brain : a Journal of Neurology. 07, 2016 | Pubmed ID: 27190009 Predicting Disease Progression in Progressive Supranuclear Palsy in Multicenter Clinical Trials Parkinsonism & Related Disorders. Jul, 2016 | Pubmed ID: 27172829 Launching the Movement Disorders Society Genetic Mutation Database (MDSGene) Movement Disorders : Official Journal of the Movement Disorder Society. 05, 2016 | Pubmed ID: 27156390 Characterization of Movement Disorder Phenomenology in Genetically Proven, Familial Frontotemporal Lobar Degeneration: A Systematic Review and Meta-Analysis PloS One. 2016 | Pubmed ID: 27100392 Proceedings of the Third Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies Frontiers in Neuroscience. 2016 | Pubmed ID: 27092042 Nomenclature of Genetic Movement Disorders: Recommendations of the International Parkinson and Movement Disorder Society Task Force Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2016 | Pubmed ID: 27079681 Unusual Tremor Syndromes: Know in Order to Recognise Journal of Neurology, Neurosurgery, and Psychiatry. Nov, 2016 | Pubmed ID: 26985048 Factors Influencing the Outcome of Deep Brain Stimulation: Placebo, Nocebo, Lessebo, and Lesion Effects Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2016 | Pubmed ID: 26952118 Contribution of Insula in Parkinson's Disease: A Quantitative Meta-analysis Study Human Brain Mapping. Apr, 2016 | Pubmed ID: 26800238 Cortical Plasticity Induction by Pairing Subthalamic Nucleus Deep-Brain Stimulation and Primary Motor Cortical Transcranial Magnetic Stimulation in Parkinson's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2016 | Pubmed ID: 26758832 Integrated Safety of Levodopa-carbidopa Intestinal Gel from Prospective Clinical Trials Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2016 | Pubmed ID: 26695437 Progression of Neuropsychiatric and Cognitive Features Due to Exons 2 to 5 Deletion in the Epsilon-sarcoglycan Gene: a Case Report Neurocase. 2016 | Pubmed ID: 26652670 Orthostatic Hypotension, Cerebral Hypoperfusion, and Visuospatial Deficits in Lewy Body Disorders Parkinsonism & Related Disorders. Jan, 2016 | Pubmed ID: 26639982 Mutation Analysis of CHCHD2 in Canadian Patients with Familial Parkinson's Disease Neurobiology of Aging. Feb, 2016 | Pubmed ID: 26639156 The Long-term Outcome of Orthostatic Tremor Journal of Neurology, Neurosurgery, and Psychiatry. Feb, 2016 | Pubmed ID: 25770124 The Saskatchewan Movement Disorders Program: Commitment Pays Off The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Mar, 2015 | Pubmed ID: 27482556 Protocol of a Randomised Delayed-start Double-blind Placebo-controlled Multi-centre Trial for Levodopa in EArly Parkinson's Disease: the LEAP-study BMC Neurology. Nov, 2015 | Pubmed ID: 26584951 Imaging Striatal Microglial Activation in Patients with Parkinson's Disease PloS One. 2015 | Pubmed ID: 26381267 Genome-wide Variant by Serum Urate Interaction in Parkinson's Disease Annals of Neurology. Nov, 2015 | Pubmed ID: 26284320 Disease-modifying Strategies for Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Sep, 2015 | Pubmed ID: 26208210 Effects of Subthalamic Nucleus Stimulation on Motor Cortex Plasticity in Parkinson Disease Neurology. Aug, 2015 | Pubmed ID: 26156511 Dopamine Agonist Withdrawal Syndrome (DAWS) Symptoms in Parkinson's Disease Patients Treated with Levodopa-carbidopa Intestinal Gel Infusion Parkinsonism & Related Disorders. Aug, 2015 | Pubmed ID: 26071817 Gene Delivery of Neurturin to Putamen and Substantia Nigra in Parkinson Disease: A Double-blind, Randomized, Controlled Trial Annals of Neurology. Aug, 2015 | Pubmed ID: 26061140 Vascular Parkinsonism: Deconstructing a Syndrome Movement Disorders : Official Journal of the Movement Disorder Society. Jun, 2015 | Pubmed ID: 25997420 Parkinson's Disease Lancet (London, England). Aug, 2015 | Pubmed ID: 25904081 Minimal Change Multiple System Atrophy: an Aggressive Variant? Movement Disorders : Official Journal of the Movement Disorder Society. Jun, 2015 | Pubmed ID: 25854893 Mutation Analysis of CHCHD10 in Different Neurodegenerative Diseases Brain : a Journal of Neurology. Sep, 2015 | Pubmed ID: 25833818 Similar Striatal D2/D3 Dopamine Receptor Availability in Adults with Tourette Syndrome Compared with Healthy Controls: A [(11) C]-(+)-PHNO and [(11) C]raclopride Positron Emission Tomography Imaging Study Human Brain Mapping. Jul, 2015 | Pubmed ID: 25788222 Response to Clozapine in a Clinically Identifiable Subtype of Schizophrenia The British Journal of Psychiatry : the Journal of Mental Science. Jun, 2015 | Pubmed ID: 25745132 Movement Disorders and Other Motor Abnormalities in Adults with 22q11.2 Deletion Syndrome American Journal of Medical Genetics. Part A. Mar, 2015 | Pubmed ID: 25684639 Practical Guidelines for Managing Adults with 22q11.2 Deletion Syndrome Genetics in Medicine : Official Journal of the American College of Medical Genetics. Aug, 2015 | Pubmed ID: 25569435 Salience Network and Parahippocampal Dopamine Dysfunction in Memory-impaired Parkinson Disease Annals of Neurology. Feb, 2015 | Pubmed ID: 25448687 In Pursuit of Prodromal Parkinson's Disease The Lancet. Neurology. Jan, 2015 | Pubmed ID: 25435388 Clinical Correlations with Lewy Body Pathology in LRRK2-related Parkinson Disease JAMA Neurology. Jan, 2015 | Pubmed ID: 25401511 Mutation Analysis of Patients with Neurodegenerative Disorders Using NeuroX Array Neurobiology of Aging. Jan, 2015 | Pubmed ID: 25174650 Investing in the Future: Stimulation of the Medial Prefrontal Cortex Reduces Discounting of Delayed Rewards Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Feb, 2015 | Pubmed ID: 25168685 Imaging Changes Associated with Cognitive Abnormalities in Parkinson's Disease Brain Structure & Function. Jul, 2015 | Pubmed ID: 24816399 Differentiating Between Visual Hallucination-free Dementia with Lewy Bodies and Corticobasal Syndrome on the Basis of Neuropsychology and Perfusion Single-photon Emission Computed Tomography Alzheimer's Research & Therapy. 2014 | Pubmed ID: 25484929 Subthalamic Nucleus-deep Brain Stimulation for Early Motor Complications in Parkinson's Disease-the EARLYSTIM Trial: Early is Not Always Better Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2014 | Pubmed ID: 25227325 Initiating Dopaminergic Treatment in Parkinson's Disease Lancet (London, England). Sep, 2014 | Pubmed ID: 24928806 Davunetide in Patients with Progressive Supranuclear Palsy: a Randomised, Double-blind, Placebo-controlled Phase 2/3 Trial The Lancet. Neurology. Jul, 2014 | Pubmed ID: 24873720 Antecollis and Levodopa-responsive Parkinsonism Are Late Features of Dravet Syndrome Neurology. Jun, 2014 | Pubmed ID: 24850485 Bilateral Pallidal Stimulation for Sargoglycan Epsilon Negative Myoclonus Parkinsonism & Related Disorders. Aug, 2014 | Pubmed ID: 24812007 Pharmacological Treatment of Parkinson Disease: a Review JAMA. Apr 23-30, 2014 | Pubmed ID: 24756517 Uncovering the Role of the Insula in Non-motor Symptoms of Parkinson's Disease Brain : a Journal of Neurology. Aug, 2014 | Pubmed ID: 24736308 Another Face of Placebo: the Lessebo Effect in Parkinson Disease: Meta-analyses Neurology. Apr, 2014 | Pubmed ID: 24658930 Peroxisomal D-bifunctional Protein Deficiency: Three Adults Diagnosed by Whole-exome Sequencing Neurology. Mar, 2014 | Pubmed ID: 24553428 A Practical Approach to Remote Longitudinal Follow-up of Parkinson's Disease: the FOUND Study Movement Disorders : Official Journal of the Movement Disorder Society. May, 2014 | Pubmed ID: 24515275 Implications of Nocturnal Symptoms Towards the Early Diagnosis of Parkinson's Disease Journal of Neural Transmission (Vienna, Austria : 1996). Aug, 2014 | Pubmed ID: 24500032 Combined Insular and Striatal Dopamine Dysfunction Are Associated with Executive Deficits in Parkinson's Disease with Mild Cognitive Impairment Brain : a Journal of Neurology. Feb, 2014 | Pubmed ID: 24334314 Longitudinal Quantitative MRI in Multiple System Atrophy and Progressive Supranuclear Palsy Parkinsonism & Related Disorders. Feb, 2014 | Pubmed ID: 24239142 The Treatment of Dystonic Tremor: a Systematic Review Journal of Neurology, Neurosurgery, and Psychiatry. Jul, 2014 | Pubmed ID: 24167042 Dopamine-agonists and Impulsivity in Parkinson's Disease: Impulsive Choices Vs. Impulsive Actions Human Brain Mapping. Jun, 2014 | Pubmed ID: 24038587 The Prion Hypothesis in Parkinson's Disease: Braak to the Future Acta Neuropathologica Communications. May, 2013 | Pubmed ID: 24252164 Movement Disorder Society Unified Parkinson Disease Rating Scale Experiences in Daily Living: Longitudinal Changes and Correlation with Other Assessments Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2013 | Pubmed ID: 24123383 Association Between Early-onset Parkinson Disease and 22q11.2 Deletion Syndrome: Identification of a Novel Genetic Form of Parkinson Disease and Its Clinical Implications JAMA Neurology. Nov, 2013 | Pubmed ID: 24018986 The Value of GRE, ADC and Routine MRI in Distinguishing Parkinsonian Disorders The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. May, 2013 | Pubmed ID: 23603177 Caffeine Consumption and Risk of Dyskinesia in CALM-PD Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2013 | Pubmed ID: 23339054 Voxel-based Imaging of Translocator Protein 18 KDa (TSPO) in High-resolution PET Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2013 | Pubmed ID: 23281426 α-Synuclein Oligomers and Clinical Implications for Parkinson Disease Annals of Neurology. Feb, 2013 | Pubmed ID: 23225525 Clinicopathological Review of Pallidonigroluysian Atrophy Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2013 | Pubmed ID: 23114877 Clinical Features of Dopamine Agonist Withdrawal Syndrome in a Movement Disorders Clinic Journal of Neurology, Neurosurgery, and Psychiatry. Feb, 2013 | Pubmed ID: 22933817 Prefrontal Dopaminergic Receptor Abnormalities and Executive Functions in Parkinson's Disease Human Brain Mapping. Jul, 2013 | Pubmed ID: 22331665 A Multi-centre Clinico-genetic Analysis of the VPS35 Gene in Parkinson Disease Indicates Reduced Penetrance for Disease-associated Variants Journal of Medical Genetics. Nov, 2012 | Pubmed ID: 23125461 Untersuchung Des C9orf72 in 4 Neurodegenerativen Erkrankungen Archives of Neurology. Sep, 2012 | Pubmed ID: 22964832 Caffeine for Treatment of Parkinson Disease: a Randomized Controlled Trial Neurology. Aug, 2012 | Pubmed ID: 22855866 Large-scale Replication and Heterogeneity in Parkinson Disease Genetic Loci Neurology. Aug, 2012 | Pubmed ID: 22786590 Extrastriatal Dopaminergic Abnormalities of DA Homeostasis in Parkinson's Patients with Medication-induced Pathological Gambling: a [11C] FLB-457 and PET Study Neurobiology of Disease. Dec, 2012 | Pubmed ID: 22766031 Associated Movement Disorders in Orthostatic Tremor Journal of Neurology, Neurosurgery, and Psychiatry. Jul, 2012 | Pubmed ID: 22577231 Premotor Parkinson's Disease: Concepts and Definitions Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2012 | Pubmed ID: 22508279 Fixing the Broken System of Genetic Locus Symbols: Parkinson Disease and Dystonia As Examples Neurology. Mar, 2012 | Pubmed ID: 22454269 Acquired Neurosyphilis Presenting As Movement Disorders Movement Disorders : Official Journal of the Movement Disorder Society. May, 2012 | Pubmed ID: 22410849 Movement Disorders on YouTube--caveat Spectator The New England Journal of Medicine. Sep, 2011 | Pubmed ID: 21992142 Development of a Non-motor Fluctuation Assessment Instrument for Parkinson Disease Parkinson's Disease. 2011 | Pubmed ID: 21860778 The Curious Case of Phenocopies in Families with Genetic Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21735483 Deep Brain Stimulation for Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Jun, 2011 | Pubmed ID: 21692109 Unilateral Subdural Motor Cortex Stimulation Improves Essential Tremor but Not Parkinson's Disease Brain : a Journal of Neurology. Jul, 2011 | Pubmed ID: 21646329 Psychogenic Movement Disorders: Past Developments, Current Status, and Future Directions Movement Disorders : Official Journal of the Movement Disorder Society. May, 2011 | Pubmed ID: 21626561 Tongue Control for Swallowing in Parkinson's Disease: Effects of Age, Rate, and Stimulus Consistency Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21542018 A Critical Appraisal of the Premotor Symptoms of Parkinson's Disease: Potential Usefulness in Early Diagnosis and Design of Neuroprotective Trials Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2011 | Pubmed ID: 21484865 Potential Placebo Effect in Assessing Idiopathic Normal Pressure Hydrocephalus Journal of Neurosurgery. May, 2011 | Pubmed ID: 21250799 Surgical Correction of Kyphosis in Patients with Camptocormia Due to Parkinson's Disease: a Retrospective Evaluation Journal of Neurology, Neurosurgery, and Psychiatry. Apr, 2011 | Pubmed ID: 20667867 Involvement of the Cerebellothalamocortical Pathway in Parkinson Disease Annals of Neurology. Dec, 2010 | Pubmed ID: 21194152 Clinical Trials of Disease-modifying Therapies for Neurodegenerative Diseases: the Challenges and the Future Nature Medicine. Nov, 2010 | Pubmed ID: 21052078 A Survey on the Impact of the Menstrual Cycle on Movement Disorders Severity The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Jul, 2010 | Pubmed ID: 20724255 Long-term Effect of Unilateral Pallidotomy on Levodopa-induced Dyskinesia Movement Disorders : Official Journal of the Movement Disorder Society. Jul, 2010 | Pubmed ID: 20568091 Standard Guidelines for Publication of Deep Brain Stimulation Studies in Parkinson's Disease (Guide4DBS-PD) Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2010 | Pubmed ID: 20544809 Extrastriatal Dopaminergic Dysfunction in Tourette Syndrome Annals of Neurology. Feb, 2010 | Pubmed ID: 20225192 Long-term Results of a Multicenter Study on Subthalamic and Pallidal Stimulation in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2010 | Pubmed ID: 20213817 The Nature and Time Course of Cortical Activation Following Subthalamic Stimulation in Parkinson's Disease Cerebral Cortex (New York, N.Y. : 1991). Aug, 2010 | Pubmed ID: 20019146 Stimulation of the Subthalamic Nucleus and Impulsivity: Release Your Horses Annals of Neurology. Dec, 2009 | Pubmed ID: 20035509 Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease The New England Journal of Medicine. Oct, 2009 | Pubmed ID: 19846850 Urate As a Predictor of the Rate of Clinical Decline in Parkinson Disease Archives of Neurology. Dec, 2009 | Pubmed ID: 19822770 Dopamine Agonists Diminish Value Sensitivity of the Orbitofrontal Cortex: a Trigger for Pathological Gambling in Parkinson's Disease? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Dec, 2009 | Pubmed ID: 19741594 Selective Enhancement of Rapid Eye Movement Sleep by Deep Brain Stimulation of the Human Pons Annals of Neurology. Jul, 2009 | Pubmed ID: 19670451 Psychogenic Movement Disorders Current Opinion in Neurology. Aug, 2009 | Pubmed ID: 19542886 Cerebral Blood Flow Changes Induced by Pedunculopontine Nucleus Stimulation in Patients with Advanced Parkinson's Disease: a [(15)O] H2O PET Study Human Brain Mapping. Dec, 2009 | Pubmed ID: 19479730 Impairments of Speed and Amplitude of Movement in Parkinson's Disease: a Pilot Study Movement Disorders : Official Journal of the Movement Disorder Society. May, 2009 | Pubmed ID: 19230031 When and How Should Treatment Be Started in Parkinson Disease? Neurology. Feb, 2009 | Pubmed ID: 19221313 Understanding Disability in Tourette Syndrome Developmental Medicine and Child Neurology. Jun, 2009 | Pubmed ID: 19018838 Non-dopaminergic Treatments in Development for Parkinson's Disease The Lancet. Neurology. Oct, 2008 | Pubmed ID: 18848312 Reduced Intracortical and Interhemispheric Inhibitions in Corticobasal Syndrome Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. Oct, 2008 | Pubmed ID: 18791478 Levodopa-related Motor Complications--phenomenology Movement Disorders : Official Journal of the Movement Disorder Society. 2008 | Pubmed ID: 18781677 Electrophysiological Features of Myoclonus-dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2008 | Pubmed ID: 18759341 RCBF Changes Associated with PPN Stimulation in a Patient with Parkinson's Disease: a PET Study Movement Disorders : Official Journal of the Movement Disorder Society. May, 2008 | Pubmed ID: 18412282 Predictors of Deterioration in Health-related Quality of Life in Parkinson's Disease: Results from the DATATOP Trial Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2008 | Pubmed ID: 18076084 The Many Faces of Corticobasal Degeneration Parkinsonism & Related Disorders. 2007 | Pubmed ID: 18267261 Subdural Motor Cortex Stimulation in Parkinson's Disease Does Not Modify Movement-related RCBF Pattern Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2007 | Pubmed ID: 17894326 Benign Hereditary Chorea Revisited: a Journey to Understanding Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2007 | Pubmed ID: 17702033 Characterization of REM-sleep Associated Ponto-geniculo-occipital Waves in the Human Pons Sleep. Jul, 2007 | Pubmed ID: 17682651 Manganese-induced Parkinsonism Associated with Methcathinone (Ephedrone) Abuse Archives of Neurology. Jun, 2007 | Pubmed ID: 17562938 Neuronal Firing Rates and Patterns in the Globus Pallidus Internus of Patients with Cervical Dystonia Differ from Those with Parkinson's Disease Journal of Neurophysiology. Aug, 2007 | Pubmed ID: 17537900 Levodopa Response in Long-term Bilateral Subthalamic Stimulation for Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. May, 2007 | Pubmed ID: 17443692 Changes in Cortical and Pallidal Oscillatory Activity During the Execution of a Sensory Trick in Patients with Cervical Dystonia Experimental Neurology. Apr, 2007 | Pubmed ID: 17307166 Interhemispheric and Ipsilateral Connections in Parkinson's Disease: Relation to Mirror Movements Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2007 | Pubmed ID: 17290459 Punding Prevalence in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Jun, 2007 | Pubmed ID: 17230464 Criteria for Deep-brain Stimulation in Parkinson's Disease: Review and Analysis Expert Review of Neurotherapeutics. Nov, 2006 | Pubmed ID: 17144783 Rapidly Progressive Sporadic Dentatorubral Pallidoluysian Atrophy with Intracytoplasmic Inclusions and No CAG Repeat Expansion Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2006 | Pubmed ID: 17078058 Beta Oscillatory Activity in the Subthalamic Nucleus and Its Relation to Dopaminergic Response in Parkinson's Disease Journal of Neurophysiology. Dec, 2006 | Pubmed ID: 17005611 Subthalamic Nucleus Stimulation: Improvements in Outcome with Reprogramming Archives of Neurology. Sep, 2006 | Pubmed ID: 16831958 Cortical and Spinal Abnormalities in Psychogenic Dystonia Annals of Neurology. May, 2006 | Pubmed ID: 16634038 Cardiac Valvulopathy Associated with Pergolide Use The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Feb, 2006 | Pubmed ID: 16583718 Motor Cortex Plasticity in Parkinson's Disease and Levodopa-induced Dyskinesias Brain : a Journal of Neurology. Apr, 2006 | Pubmed ID: 16476674 Randomized Controlled Trial of Intraputamenal Glial Cell Line-derived Neurotrophic Factor Infusion in Parkinson Disease Annals of Neurology. Mar, 2006 | Pubmed ID: 16429411 Progress in Clinical Neurosciences: a Forum on the Early Management of Parkinson's Disease The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Aug, 2005 | Pubmed ID: 16225167 Psychiatric Symptoms in Patients with Parkinson Disease Presenting for Deep Brain Stimulation Surgery Journal of Neurosurgery. Aug, 2005 | Pubmed ID: 16175853 Atypical Absences and Recurrent Absence Status in an Adult with Angelman Syndrome Due to the UBE3A Mutation Epileptic Disorders : International Epilepsy Journal with Videotape. Sep, 2005 | Pubmed ID: 16162432 Firing Rates of Pallidal Neurons Are Similar in Huntington's and Parkinson's Disease Patients Experimental Brain Research. Oct, 2005 | Pubmed ID: 16082534 Apraxia in Movement Disorders Brain : a Journal of Neurology. Jul, 2005 | Pubmed ID: 15930045 Pallidal Deep Brain Stimulation Influences Both Reflexive and Voluntary Saccades in Huntington's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2005 | Pubmed ID: 15580556 Analysis of the Glucocerebrosidase Gene in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2005 | Pubmed ID: 15517592 Analysis of the PINK1 Gene in a Large Cohort of Cases with Parkinson Disease Archives of Neurology. Dec, 2004 | Pubmed ID: 15596610 Genetic Association Study of PINK1 Coding Polymorphisms in Parkinson's Disease Neuroscience Letters. Dec, 2004 | Pubmed ID: 15542245 Neuronal Activity in the Globus Pallidus of Multiple System Atrophy Patients Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2004 | Pubmed ID: 15390066 Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease After Successful Pallidotomy: Clinical and Electrophysiological Observations Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2004 | Pubmed ID: 15390008 Presentation of Creutzfeldt-Jakob Disease As Acute Corticobasal Degeneration Syndrome Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2004 | Pubmed ID: 15300662 Antidepressants in the Treatment of Psychosis with Comorbid Depression in Parkinson Disease Clinical Neuropharmacology. Mar-Apr, 2004 | Pubmed ID: 15252271 Clinical Findings in a Large Family with a Parkin Ex3delta40 Mutation Archives of Neurology. May, 2004 | Pubmed ID: 15148147 Sporadic Case of Dentatorubral Pallidoluysian Atrophy with No CAG Repeat Expansion and No Intranuclear Inclusions Movement Disorders : Official Journal of the Movement Disorder Society. May, 2004 | Pubmed ID: 15133824 Challenges in Parkinson's Disease: Restoration of the Nigrostriatal Dopamine System is Not Enough The Lancet. Neurology. May, 2004 | Pubmed ID: 15099546 Gestes Antagonistes in Psychogenic Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2004 | Pubmed ID: 15022189 Quality of Life in Early Parkinson's Disease: Impact of Dyskinesias and Motor Fluctuations Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2004 | Pubmed ID: 14743356 Predictors of Impaired Daytime Sleep and Wakefulness in Patients with Parkinson Disease Treated with Older (ergot) Vs Newer (nonergot) Dopamine Agonists Archives of Neurology. Jan, 2004 | Pubmed ID: 14732626 Deep Brain Stimulation for Parkinson's Disease Dissociates Mood and Motor Circuits: a Functional MRI Case Study Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2003 | Pubmed ID: 14673888 Posttraumatic Painful Torticollis Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2003 | Pubmed ID: 14673885 Long-term Follow-up of Thalamic Deep Brain Stimulation for Essential and Parkinsonian Tremor Neurology. Dec, 2003 | Pubmed ID: 14663050 Motor Cortical Stimulation for Parkinsonism in Multiple System Atrophy Archives of Neurology. Nov, 2003 | Pubmed ID: 14623727 Subthalamic Stimulation for Parkinson's Disease--living Better Electrically? The New England Journal of Medicine. Nov, 2003 | Pubmed ID: 14614163 Stimulation of the Subthalamic Nucleus in Parkinson's Disease Does Not Produce Striatal Dopamine Release Neurosurgery. Nov, 2003 | Pubmed ID: 14580276 Corticobasal Degeneration: Selected Developments Movement Disorders : Official Journal of the Movement Disorder Society. Sep, 2003 | Pubmed ID: 14502656 Long-term Follow Up of Bilateral Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson Disease Journal of Neurosurgery. Sep, 2003 | Pubmed ID: 12959435 Unique Form of Propriospinal Myoclonus As a Possible Complication of an Enteropathogenic Toxin Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2003 | Pubmed ID: 12889087 Tics Current Opinion in Neurology. Aug, 2003 | Pubmed ID: 12869813 Psychogenic Movement Disorders The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Mar, 2003 | Pubmed ID: 12691482 Pallidal Neuronal Activity: Implications for Models of Dystonia Annals of Neurology. Apr, 2003 | Pubmed ID: 12666115 Neurodegenerative Disease and the Evolution of Art: the Effects of Presumed Corticobasal Degeneration in a Professional Artist Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2003 | Pubmed ID: 12621633 Acute Effect of Transcutaneous Electrical Nerve Stimulation on Tremor Movement Disorders : Official Journal of the Movement Disorder Society. Feb, 2003 | Pubmed ID: 12539214 Localization of Clinically Effective Stimulating Electrodes in the Human Subthalamic Nucleus on Magnetic Resonance Imaging Journal of Neurosurgery. Nov, 2002 | Pubmed ID: 12450038 Predicting Motor Decline and Disability in Parkinson Disease: a Systematic Review Archives of Neurology. Nov, 2002 | Pubmed ID: 12433259 Neonatal Ablation of the Nigrostriatal Dopamine Pathway Does Not Influence Limb Development in Rats Experimental Neurology. Oct, 2002 | Pubmed ID: 12429200 Dependence of Subthalamic Nucleus Oscillations on Movement and Dopamine in Parkinson's Disease Brain : a Journal of Neurology. Jun, 2002 | Pubmed ID: 12023310 Long-term Hardware-related Complications of Deep Brain Stimulation Neurosurgery. Jun, 2002 | Pubmed ID: 12015845 A Major Locus for Myoclonus-dystonia Maps to Chromosome 7q in Eight Families American Journal of Human Genetics. Nov, 2000 | Pubmed ID: 11022010 Gezielte Sequenzierung der nächsten Generation und Bioinformatik-Pipeline, um genetische Determinanten der konstitutionelle Krankheit zu bewerten Allison A. Dilliott1,2, Sali M.K. Farhan3, Mahdi Ghani4, Christine Sato4, Eric Liang5, Ming Zhang4, Adam D. McIntyre1, Henian Cao1, Lemuel Racacho6,7, John F. Robinson1, Michael J. Strong1,8, Mario Masellis9,10, Dennis E. Bulman6,7, Ekaterina Rogaeva4, Anthony Lang10,11, Carmela Tartaglia4,10, Elizabeth Finger12,13, Lorne Zinman9, John Turnbull14, Morris Freedman10,15, Rick Swartz9, Sandra E. Black9,16, Robert A. Hegele1,2 1Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, 2Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, 3Analytic and Translational Genetics Unit, Center for Genomic Medicine, Harvard Medical School, Massachusetts General Hospital, Stanley Centre for Psychiatric Research, Broad Institute of MIT and Harvard, 4Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 5School of Medicine, Faculty of Health Sciences, Queen's University, 6Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 7CHEO Research Institute, Faculty of Medicine, University of Ottawa, 8Department of Clinical Neurological Sciences, Western University, 9Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 10Division of Neurology, Department of Medicine, University of Toronto, 11Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, 12Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 13Parkwood Institute, St. Joseph's Health Care, 14Department of Medicine, Division of Neurology, McMaster University, 15Division of Neurology, Department of Medicine, Baycrest Health Sciences, 16Canadian Partnership for Stroke Recovery Sunnybrook Site, Sunnybrook Health Science Centre, University of Toronto JoVE 57266 Genetics
Gezielte Sequenzierung der nächsten Generation und Bioinformatik-Pipeline, um genetische Determinanten der konstitutionelle Krankheit zu bewerten Allison A. Dilliott1,2, Sali M.K. Farhan3, Mahdi Ghani4, Christine Sato4, Eric Liang5, Ming Zhang4, Adam D. McIntyre1, Henian Cao1, Lemuel Racacho6,7, John F. Robinson1, Michael J. Strong1,8, Mario Masellis9,10, Dennis E. Bulman6,7, Ekaterina Rogaeva4, Anthony Lang10,11, Carmela Tartaglia4,10, Elizabeth Finger12,13, Lorne Zinman9, John Turnbull14, Morris Freedman10,15, Rick Swartz9, Sandra E. Black9,16, Robert A. Hegele1,2 1Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, 2Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, 3Analytic and Translational Genetics Unit, Center for Genomic Medicine, Harvard Medical School, Massachusetts General Hospital, Stanley Centre for Psychiatric Research, Broad Institute of MIT and Harvard, 4Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 5School of Medicine, Faculty of Health Sciences, Queen's University, 6Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 7CHEO Research Institute, Faculty of Medicine, University of Ottawa, 8Department of Clinical Neurological Sciences, Western University, 9Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 10Division of Neurology, Department of Medicine, University of Toronto, 11Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, 12Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 13Parkwood Institute, St. Joseph's Health Care, 14Department of Medicine, Division of Neurology, McMaster University, 15Division of Neurology, Department of Medicine, Baycrest Health Sciences, 16Canadian Partnership for Stroke Recovery Sunnybrook Site, Sunnybrook Health Science Centre, University of Toronto JoVE 57266 Genetics