Antonis K. Hatzopoulos Department of Medicine, Division of Cardiovascular Medicine Vanderbilt University School of Medicine Biography Publications Institution JoVE Articles Antonis K. Hatzopoulos has not added a biography. If you are Antonis K. Hatzopoulos and would like to personalize this page please email our Author Liaison for assistance. Publications Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension Hypertension. Feb, 2016 | Pubmed ID: 26693821 Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis Circulation Research. Oct, 2015 | Pubmed ID: 26338900 Endothelial Cells Contribute to Generation of Adult Ventricular Myocytes During Cardiac Homeostasis Cell Reports. Jul, 2014 | Pubmed ID: 25001281 Endothelial Progenitor Cells Augment Collateralization and Hemodynamic Rescue in a Model of Chronic Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2014 | Pubmed ID: 24780900 Gremlin 2 Promotes Differentiation of Embryonic Stem Cells to Atrial Fate by Activation of the JNK Signaling Pathway Stem Cells (Dayton, Ohio). Jul, 2014 | Pubmed ID: 24648383 SDF-1 Fused to a Fractalkine Stalk and a GPI Anchor Enables Functional Neovascularization Stem Cells (Dayton, Ohio). Sep, 2013 | Pubmed ID: 23744498 Functional Modeling in Zebrafish Demonstrates That the Atrial-fibrillation-associated Gene GREM2 Regulates Cardiac Laterality, Cardiomyocyte Differentiation and Atrial Rhythm Disease Models & Mechanisms. Mar, 2013 | Pubmed ID: 23223679 Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: the TIME Randomized Trial JAMA : the Journal of the American Medical Association. Dec, 2012 | Pubmed ID: 23129008 Egr-1 Induces DARPP-32 Expression in Striatal Medium Spiny Neurons Via a Conserved Intragenic Element The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2012 | Pubmed ID: 22593050 機能的能力、左心室機能および慢性心不全における灌流に及ぼす自家骨髄単核細胞の Transendocardial 配信の: フォーカス CCTRN トライアル。 JAMA : the Journal of the American Medical Association. Mar, 2012 | Pubmed ID: 22447880 Continuous Antagonism by Dkk1 Counter Activates Canonical Wnt Signaling and Promotes Cardiomyocyte Differentiation of Embryonic Stem Cells Stem Cells and Development. Jan, 2012 | Pubmed ID: 21861760 Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis Recent Patents on Regenerative Medicine. Sep, 2011 | Pubmed ID: 22787575 コンビナトリアル高分子エレクトロ行列は、生理学的に関連Cardiomyogenic幹細胞の分化を促進する PloS One. 2011 | Pubmed ID: 22216144 Discovering Small Molecules That Promote Cardiomyocyte Generation by Modulating Wnt Signaling Chemistry & Biology. Dec, 2011 | Pubmed ID: 22195568 Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: the LateTIME Randomized Trial JAMA : the Journal of the American Medical Association. Nov, 2011 | Pubmed ID: 22084195 プログラム的な変更:誘導多能性の時代における肺疾患の研究 American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2011 | Pubmed ID: 21984571 Tfap2a and Foxd3 Regulate Early Steps in the Development of the Neural Crest Progenitor Population Developmental Biology. Dec, 2011 | Pubmed ID: 21963426 The Feelgood Mutation in Zebrafish Dysregulates COPII-dependent Secretion of Select Extracellular Matrix Proteins in Skeletal Morphogenesis Disease Models & Mechanisms. Nov, 2011 | Pubmed ID: 21729877 Preconditioned Endothelial Progenitor Cells Reduce Formation of Melanoma Metastases Through SPARC-driven Cell-cell Interactions and Endocytosis Cancer Research. Jul, 2011 | Pubmed ID: 21616936 Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation Circulation Research. Jul, 2011 | Pubmed ID: 21597012 Experimental Myocardial Infarction Triggers Canonical Wnt Signaling and Endothelial-to-mesenchymal Transition Disease Models & Mechanisms. Jul, 2011 | Pubmed ID: 21324930 Neuregulin-1β Regulation of Embryonic Endothelial Progenitor Cell Survival American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2011 | Pubmed ID: 21239627 Role of Guanylate Binding Protein-1 in Vascular Defects Associated with Chronic Inflammatory Diseases Journal of Cellular and Molecular Medicine. Jul, 2011 | Pubmed ID: 20716116 Time is Like a Clock in My Heart: Implications for Stem Cell Delivery After Myocardial Infarction Cardiology. 2010 | Pubmed ID: 21042016 LateTIME: a Phase-II, Randomized, Double-blinded, Placebo-controlled, Pilot Trial Evaluating the Safety and Effect of Administration of Bone Marrow Mononuclear Cells 2 to 3 Weeks After Acute Myocardial Infarction Texas Heart Institute Journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 2010 | Pubmed ID: 20844613 Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells for Patients with Chronic Ischemic Heart Disease and Left Ventricular Dysfunction (First Mononuclear Cells Injected in the US [FOCUS]): Rationale and Design American Heart Journal. Aug, 2010 | Pubmed ID: 20691824 Thymosin Beta4: a Key Factor for Protective Effects of EEPCs in Acute and Chronic Ischemia Annals of the New York Academy of Sciences. Apr, 2010 | Pubmed ID: 20536456 Adriamycin Nephropathy: a Failure of Endothelial Progenitor Cell-induced Repair The American Journal of Pathology. Apr, 2010 | Pubmed ID: 20167859 Stem Cell Therapy: Pieces of the Puzzle Journal of Cardiovascular Translational Research. Feb, 2010 | Pubmed ID: 20119487 NF KappaB Activation in Embryonic Endothelial Progenitor Cells Enhances Neovascularization Via PSGL-1 Mediated Recruitment: Novel Role for LL37 Stem Cells (Dayton, Ohio). Feb, 2010 | Pubmed ID: 20014279 FunGenESデータベース:マウス胚性幹細胞の分化のためのゲノムリソース PloS One. 2009 | Pubmed ID: 19727443 Rationale and Design for TIME: A Phase II, Randomized, Double-blind, Placebo-controlled Pilot Trial Evaluating the Safety and Effect of Timing of Administration of Bone Marrow Mononuclear Cells After Acute Myocardial Infarction American Heart Journal. Sep, 2009 | Pubmed ID: 19699857 Stem Cell Therapy for Cardiac Repair: Benefits and Barriers Expert Reviews in Molecular Medicine. 2009 | Pubmed ID: 19586557 Cardiac Repair and Regeneration: the Rubik's Cube of Cell Therapy for Heart Disease Disease Models & Mechanisms. Jul-Aug, 2009 | Pubmed ID: 19553696 T17b Murine Embryonal Endothelial Progenitor Cells Can Be Induced Towards Both Proliferation and Differentiation in a Fibrin Matrix Journal of Cellular and Molecular Medicine. May, 2009 | Pubmed ID: 19538255 Dorsomorphin、BMPシグナル伝達の選択的小分子阻害剤は、胚性幹細胞のCardiomyogenesisを促進する PloS One. 2008 | Pubmed ID: 18682835 Egr-1 Regulates Expression of the Glial Scar Component Phosphacan in Astrocytes After Experimental Stroke The American Journal of Pathology. Jul, 2008 | Pubmed ID: 18556777 Thymosin Beta4 is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell-mediated Cardioprotection Circulation. Apr, 2008 | Pubmed ID: 18427126 B-Raf-mediated Signaling Pathway Regulates T Cell Development European Journal of Immunology. Feb, 2008 | Pubmed ID: 18228248 心臓微小血管内皮細胞への内皮前駆細胞のアデノシン受容体を介した接着 Circulation Research. Feb, 2008 | Pubmed ID: 18032734 Rafs Constitute a Nodal Point in the Regulation of Embryonic Endothelial Progenitor Cell Growth and Differentiation Journal of Cellular and Molecular Medicine. Nov-Dec, 2007 | Pubmed ID: 18205709 血管内皮前駆細胞および細胞治療のための潜在能力の生物学的特性 Progress in Cardiovascular Diseases. May-Jun, 2007 | Pubmed ID: 17498522 Platelet-induced Differentiation of Endothelial Progenitor Cells Seminars in Thrombosis and Hemostasis. Mar, 2007 | Pubmed ID: 17340461 Hypoxia-mediated Activation of Dll4-Notch-Hey2 Signaling in Endothelial Progenitor Cells and Adoption of Arterial Cell Fate Experimental Cell Research. Jan, 2007 | Pubmed ID: 17045587 The Mother Superior Mutation Ablates Foxd3 Activity in Neural Crest Progenitor Cells and Depletes Neural Crest Derivatives in Zebrafish Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2006 | Pubmed ID: 17013879 Expression of the Protein Related to Dan and Cerberus Gene--prdc--During Eye, Pharyngeal Arch, Somite, and Swim Bladder Development in Zebrafish Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2006 | Pubmed ID: 16921498 Coordinated Changes of Histone Modifications and HDAC Mobilization Regulate the Induction of MHC Class II Genes by Trichostatin A Nucleic Acids Research. 2006 | Pubmed ID: 16452299 Adherent Platelets Recruit and Induce Differentiation of Murine Embryonic Endothelial Progenitor Cells to Mature Endothelial Cells in Vitro Circulation Research. Feb, 2006 | Pubmed ID: 16373597 Retroinfusion of Embryonic Endothelial Progenitor Cells Attenuates Ischemia-reperfusion Injury in Pigs: Role of Phosphatidylinositol 3-kinase/AKT Kinase Circulation. Aug, 2005 | Pubmed ID: 16159802 Embryonic Endothelial Progenitor Cells Expressing a Broad Range of Proangiogenic and Remodeling Factors Enhance Vascularization and Tissue Recovery in Acute and Chronic Ischemia FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2005 | Pubmed ID: 16009705 Cytoplasmic Thioredoxin Reductase is Essential for Embryogenesis but Dispensable for Cardiac Development Molecular and Cellular Biology. Mar, 2005 | Pubmed ID: 15713651 Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function Molecular and Cellular Biology. Nov, 2004 | Pubmed ID: 15485910 Embryonic Endothelial Progenitor Cells Armed with a Suicide Gene Target Hypoxic Lung Metastases After Intravenous Delivery Cancer Cell. May, 2004 | Pubmed ID: 15144955 Multistep Nature of Microvascular Recruitment of Ex Vivo-expanded Embryonic Endothelial Progenitor Cells During Tumor Angiogenesis The Journal of Experimental Medicine. Jun, 2003 | Pubmed ID: 12810693 Participation of Bone Marrow-derived Cells in Long-term Repair Processes After Experimental Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2003 | Pubmed ID: 12796719 BMPアンタゴニストGrem2を使用した多能性幹細胞から心房心筋細胞の分化 Jeffery B. Bylund1,2, Antonis K. Hatzopoulos1,3 1Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2Department of Pharmacology, Vanderbilt University, 3Department of Cell & Developmental Biology, Vanderbilt University School of Medicine Developmental Biology
BMPアンタゴニストGrem2を使用した多能性幹細胞から心房心筋細胞の分化 Jeffery B. Bylund1,2, Antonis K. Hatzopoulos1,3 1Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2Department of Pharmacology, Vanderbilt University, 3Department of Cell & Developmental Biology, Vanderbilt University School of Medicine Developmental Biology