Barry J. Grant Department of Computational Medicine and Bioinformatics University of Michigan Medical School Biography Publications Institution JoVE Articles Barry J. Grant has not added a biography. If you are Barry J. Grant and would like to personalize this page please email our Author Liaison for assistance. Publications Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells Molecular Cell. Mar, 2017 | Pubmed ID: 28306507 Computational and Biochemical Characterization of Two Partially Overlapping Interfaces and Multiple Weak-affinity K-Ras Dimers Scientific Reports. Jan, 2017 | Pubmed ID: 28067274 Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies Cell Chemical Biology. Jan, 2017 | Pubmed ID: 28042045 Online Interactive Analysis of Protein Structure Ensembles with Bio3D-web Bioinformatics (Oxford, England). Nov, 2016 | Pubmed ID: 27423893 Rapid Characterization of Allosteric Networks with Ensemble Normal Mode Analysis The Journal of Physical Chemistry. B. Aug, 2016 | Pubmed ID: 27056373 Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26703464 Mapping the Processivity Determinants of the Kinesin-3 Motor Domain Biophysical Journal. Oct, 2015 | Pubmed ID: 26488644 Enrichment of Druggable Conformations from Apo Protein Structures Using Cosolvent-accelerated Molecular Dynamics Biology. Apr, 2015 | Pubmed ID: 25906084 Integrating Protein Structural Dynamics and Evolutionary Analysis with Bio3D BMC Bioinformatics. Dec, 2014 | Pubmed ID: 25491031 Kinesin-5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck-linker Binding Sites Biophysical Journal. Nov, 2014 | Pubmed ID: 25418105 Mapping the Structural and Dynamical Features of Kinesin Motor Domains PLoS Computational Biology. 2013 | Pubmed ID: 24244137 Domain-opening and Dynamic Coupling in the α-subunit of Heterotrimeric G Proteins Biophysical Journal. Jul, 2013 | Pubmed ID: 23870276 LeuT Conformational Sampling Utilizing Accelerated Molecular Dynamics and Principal Component Analysis Biophysical Journal. Jul, 2012 | Pubmed ID: 22828348 Calcium Binding and Allosteric Signaling Mechanisms for the Sarcoplasmic Reticulum Ca²+ ATPase Protein Science : a Publication of the Protein Society. Oct, 2012 | Pubmed ID: 22821874 Identification of Potential Small Molecule Binding Pockets on Rho Family GTPases PloS One. 2012 | Pubmed ID: 22815826 Drug Hypersensitivity Caused by Alteration of the MHC-presented Self-peptide Repertoire Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22645359 Electrostatically Biased Binding of Kinesin to Microtubules PLoS Biology. Nov, 2011 | Pubmed ID: 22140358 Induced Fit or Conformational Selection? The Role of the Semi-closed State in the Maltose Binding Protein Biochemistry. Dec, 2011 | Pubmed ID: 22050600 Novel Allosteric Sites on Ras for Lead Generation PloS One. 2011 | Pubmed ID: 22046245 Large-scale Conformational Changes of Trypanosoma Cruzi Proline Racemase Predicted by Accelerated Molecular Dynamics Simulation PLoS Computational Biology. Oct, 2011 | Pubmed ID: 22022240 Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics PLoS Computational Biology. Apr, 2011 | Pubmed ID: 21533070 Conformational Selection in G-proteins: Lessons from Ras and Rho Biophysical Journal. Dec, 2010 | Pubmed ID: 21112273 The Distinct Conformational Dynamics of K-Ras and H-Ras A59G PLoS Computational Biology. 2010 | Pubmed ID: 20838576 Large Conformational Changes in Proteins: Signaling and Other Functions Current Opinion in Structural Biology. Apr, 2010 | Pubmed ID: 20060708 Novel Procedure for Thermal Equilibration in Molecular Dynamics Simulation Molecular Simulation. Apr, 2009 | Pubmed ID: 25125797 Ras Conformational Switching: Simulating Nucleotide-dependent Conformational Transitions with Accelerated Molecular Dynamics PLoS Computational Biology. Mar, 2009 | Pubmed ID: 19300489 Mapping the Nucleotide and Isoform-dependent Structural and Dynamical Features of Ras Proteins Structure (London, England : 1993). Jun, 2008 | Pubmed ID: 18547521 The 2006 Automated Function Prediction Meeting BMC Bioinformatics. May, 2007 | Pubmed ID: 17570143 Multivariate Analysis of Conserved Sequence-structure Relationships in Kinesins: Coupling of the Active Site and a Tubulin-binding Sub-domain Journal of Molecular Biology. May, 2007 | Pubmed ID: 17399740 Bio3d: an R Package for the Comparative Analysis of Protein Structures Bioinformatics (Oxford, England). Nov, 2006 | Pubmed ID: 16940322 SgTarget: a Target Selection Resource for Structural Genomics Nucleic Acids Research. Jul, 2006 | Pubmed ID: 16844998 研究与Bio3D-web的蛋白质序列 - 结构 - 动力学关系 Shashank Jariwala*1, Lars Skjærven*2, Xin-Qiu Yao1, Barry J. Grant1 1Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, 2Department of Biomedicine, University of Bergen JoVE 55640 Biochemistry
研究与Bio3D-web的蛋白质序列 - 结构 - 动力学关系 Shashank Jariwala*1, Lars Skjærven*2, Xin-Qiu Yao1, Barry J. Grant1 1Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, 2Department of Biomedicine, University of Bergen JoVE 55640 Biochemistry
