Barry J. Grant Department of Computational Medicine and Bioinformatics University of Michigan Medical School Biography Publications Institution JoVE Articles Barry J. Grant has not added a biography. If you are Barry J. Grant and would like to personalize this page please email our Author Liaison for assistance. Publications Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells Molecular Cell. Mar, 2017 | Pubmed ID: 28306507 Computational and Biochemical Characterization of Two Partially Overlapping Interfaces and Multiple Weak-affinity K-Ras Dimers Scientific Reports. Jan, 2017 | Pubmed ID: 28067274 Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies Cell Chemical Biology. Jan, 2017 | Pubmed ID: 28042045 Online Interactive Analysis of Protein Structure Ensembles with Bio3D-web Bioinformatics (Oxford, England). Nov, 2016 | Pubmed ID: 27423893 Rapid Characterization of Allosteric Networks with Ensemble Normal Mode Analysis The Journal of Physical Chemistry. B. Aug, 2016 | Pubmed ID: 27056373 Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26703464 Mapping the Processivity Determinants of the Kinesin-3 Motor Domain Biophysical Journal. Oct, 2015 | Pubmed ID: 26488644 Enrichment of Druggable Conformations from Apo Protein Structures Using Cosolvent-accelerated Molecular Dynamics Biology. Apr, 2015 | Pubmed ID: 25906084 Integrating Protein Structural Dynamics and Evolutionary Analysis with Bio3D BMC Bioinformatics. Dec, 2014 | Pubmed ID: 25491031 Kinesin-5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck-linker Binding Sites Biophysical Journal. Nov, 2014 | Pubmed ID: 25418105 Mapping the Structural and Dynamical Features of Kinesin Motor Domains PLoS Computational Biology. 2013 | Pubmed ID: 24244137 Domain-opening and Dynamic Coupling in the α-subunit of Heterotrimeric G Proteins Biophysical Journal. Jul, 2013 | Pubmed ID: 23870276 LeuT Conformational Sampling Utilizing Accelerated Molecular Dynamics and Principal Component Analysis Biophysical Journal. Jul, 2012 | Pubmed ID: 22828348 Calcium Binding and Allosteric Signaling Mechanisms for the Sarcoplasmic Reticulum Ca²+ ATPase Protein Science : a Publication of the Protein Society. Oct, 2012 | Pubmed ID: 22821874 Identification of Potential Small Molecule Binding Pockets on Rho Family GTPases PloS One. 2012 | Pubmed ID: 22815826 Drug Hypersensitivity Caused by Alteration of the MHC-presented Self-peptide Repertoire Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22645359 Electrostatically Biased Binding of Kinesin to Microtubules PLoS Biology. Nov, 2011 | Pubmed ID: 22140358 Induced Fit or Conformational Selection? The Role of the Semi-closed State in the Maltose Binding Protein Biochemistry. Dec, 2011 | Pubmed ID: 22050600 Novel Allosteric Sites on Ras for Lead Generation PloS One. 2011 | Pubmed ID: 22046245 Large-scale Conformational Changes of Trypanosoma Cruzi Proline Racemase Predicted by Accelerated Molecular Dynamics Simulation PLoS Computational Biology. Oct, 2011 | Pubmed ID: 22022240 Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics PLoS Computational Biology. Apr, 2011 | Pubmed ID: 21533070 Conformational Selection in G-proteins: Lessons from Ras and Rho Biophysical Journal. Dec, 2010 | Pubmed ID: 21112273 The Distinct Conformational Dynamics of K-Ras and H-Ras A59G PLoS Computational Biology. 2010 | Pubmed ID: 20838576 Large Conformational Changes in Proteins: Signaling and Other Functions Current Opinion in Structural Biology. Apr, 2010 | Pubmed ID: 20060708 Novel Procedure for Thermal Equilibration in Molecular Dynamics Simulation Molecular Simulation. Apr, 2009 | Pubmed ID: 25125797 Ras Conformational Switching: Simulating Nucleotide-dependent Conformational Transitions with Accelerated Molecular Dynamics PLoS Computational Biology. Mar, 2009 | Pubmed ID: 19300489 Mapping the Nucleotide and Isoform-dependent Structural and Dynamical Features of Ras Proteins Structure (London, England : 1993). Jun, 2008 | Pubmed ID: 18547521 The 2006 Automated Function Prediction Meeting BMC Bioinformatics. May, 2007 | Pubmed ID: 17570143 Multivariate Analysis of Conserved Sequence-structure Relationships in Kinesins: Coupling of the Active Site and a Tubulin-binding Sub-domain Journal of Molecular Biology. May, 2007 | Pubmed ID: 17399740 Bio3d: an R Package for the Comparative Analysis of Protein Structures Bioinformatics (Oxford, England). Nov, 2006 | Pubmed ID: 16940322 SgTarget: a Target Selection Resource for Structural Genomics Nucleic Acids Research. Jul, 2006 | Pubmed ID: 16844998 Étude de la séquence des protéines - structure-dynamique Relations avec Bio3D-web Shashank Jariwala*1, Lars Skjærven*2, Xin-Qiu Yao1, Barry J. Grant1 1Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, 2Department of Biomedicine, University of Bergen JoVE 55640 Biochemistry
Étude de la séquence des protéines - structure-dynamique Relations avec Bio3D-web Shashank Jariwala*1, Lars Skjærven*2, Xin-Qiu Yao1, Barry J. Grant1 1Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, 2Department of Biomedicine, University of Bergen JoVE 55640 Biochemistry