Bevin P. Engelward Department of Biological Engineering Massachusetts Institute of Technology Biography Publications Institution JoVE Articles Bevin P. Engelward has not added a biography. If you are Bevin P. Engelward and would like to personalize this page please email our Author Liaison for assistance. Publications DNA Glycosylase Activity and Cell Proliferation Are Key Factors in Modulating Homologous Recombination in Vivo Carcinogenesis. Aug, 2014 | Pubmed ID: 25155011 Micro-RNAs in Regenerating Lungs: an Integrative Systems Biology Analysis of Murine Influenza Pneumonia BMC Genomics. 2014 | Pubmed ID: 25015185 Cytoplasmic and Nuclear Toxicity of 3,5-dimethylaminophenol and Potential Protection by Selenocompounds Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Oct, 2014 | Pubmed ID: 25014158 Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-dependence of Homologous Recombination in Mammals in Vivo PLoS Genetics. Jun, 2014 | Pubmed ID: 24901438 High-throughput Screening Platform for Engineered Nanoparticle-mediated Genotoxicity Using CometChip Technology ACS Nano. Mar, 2014 | Pubmed ID: 24617523 Molecular Analysis of Serum and Bronchoalveolar Lavage in a Mouse Model of Influenza Reveals Markers of Disease Severity That Can Be Clinically Useful in Humans PloS One. 2014 | Pubmed ID: 24505273 Investigating the Efficacy of Pamidronate, a Chemical Inhibitor of Farnesyl Pyrophosphate Synthase, in the Inhibition of Influenza Virus Infection In vitro and In vivo Molecular Medicine Reports. Jan, 2014 | Pubmed ID: 24154548 Standard Fluorescent Imaging of Live Cells is Highly Genotoxic Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jun, 2013 | Pubmed ID: 23650257 Building on the Past, Shaping the Future: the Environmental Mutagenesis and Genomics Society Environmental and Molecular Mutagenesis. Apr, 2013 | Pubmed ID: 23444128 Single-cell Microarray Enables High-throughput Evaluation of DNA Double-strand Breaks and DNA Repair Inhibitors Cell Cycle (Georgetown, Tex.). Mar, 2013 | Pubmed ID: 23422001 Peptide Targeting and Imaging of Damaged Lung Tissue in Influenza-infected Mice Future Microbiology. Feb, 2013 | Pubmed ID: 23374130 Neutrophils Infected with Highly Virulent Influenza H3N2 Virus Exhibit Augmented Early Cell Death and Rapid Induction of Type I Interferon Signaling Pathways Genomics. Nov, 2012 | Pubmed ID: 23195410 Genotoxicity of 2,6- and 3,5-dimethylaniline in Cultured Mammalian Cells: the Role of Reactive Oxygen Species Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2012 | Pubmed ID: 22831970 Integrated Molecular Analysis Indicates Undetectable Change in DNA Damage in Mice After Continuous Irradiation at ~ 400-fold Natural Background Radiation Environmental Health Perspectives. Aug, 2012 | Pubmed ID: 22538203 Major Shifts in the Spatio-temporal Distribution of Lung Antioxidant Enzymes During Influenza Pneumonia PloS One. 2012 | Pubmed ID: 22355371 Differential Pulmonary Transcriptomic Profiles in Murine Lungs Infected with Low and Highly Virulent Influenza H3N2 Viruses Reveal Dysregulation of TREM1 Signaling, Cytokines, and Chemokines Functional & Integrative Genomics. Mar, 2012 | Pubmed ID: 21874528 XRCC1 and Base Excision Repair Balance in Response to Nitric Oxide DNA Repair. Dec, 2011 | Pubmed ID: 22041025 P53 Null Fluorescent Yellow Direct Repeat (FYDR) Mice Have Normal Levels of Homologous Recombination DNA Repair. Dec, 2011 | Pubmed ID: 21993421 The Flap About ATM & MRE11 Cell Cycle (Georgetown, Tex.). Aug, 2010 | Pubmed ID: 20814231 Single Cell Trapping and DNA Damage Analysis Using Microwell Arrays Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534572 Development and Characterization of a Novel Variable Low Dose-rate Irradiator for in Vivo Mouse Studies Health Physics. May, 2010 | Pubmed ID: 20386202 Investigation of the Effects of Aging on Homologous Recombination in Long-term Bone Marrow Cultures In Vivo (Athens, Greece). Sep-Oct, 2009 | Pubmed ID: 19779099 Quantitative Morphometric Measurements Using Site Selective Image Cytometry of Intact Tissue Journal of the Royal Society, Interface / the Royal Society. Feb, 2009 | Pubmed ID: 19049958 Multiscale Structural Analysis of Mouse Lingual Myoarchitecture Employing Diffusion Spectrum Magnetic Resonance Imaging and Multiphoton Microscopy Journal of Biomedical Optics. Nov-Dec, 2008 | Pubmed ID: 19123652 Integrated One- and Two-photon Imaging Platform Reveals Clonal Expansion As a Major Driver of Mutation Load Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18647827 Tissue-specific Differences in the Accumulation of Sequence Rearrangements with Age DNA Repair. May, 2008 | Pubmed ID: 18358792 Three-dimensional Tissue Cytometer Based on High-speed Multiphoton Microscopy Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2007 | Pubmed ID: 17929292 DNA Double-strand Break Repair: from Mechanistic Understanding to Cancer Treatment DNA Repair. Jul, 2007 | Pubmed ID: 17363343 Open Access to Research is in the Public Interest PLoS Biology. Feb, 2007 | Pubmed ID: 17298181 Applications of Fluorescence for Detecting Rare Sequence Rearrangements in Vivo Cell Cycle (Georgetown, Tex.). Dec, 2006 | Pubmed ID: 17172860 Age-dependent Accumulation of Recombinant Cells in the Mouse Pancreas Revealed by in Situ Fluorescence Imaging Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16882718 Homologous Recombination Prevents Methylation-induced Toxicity in Escherichia Coli Nucleic Acids Research. 2006 | Pubmed ID: 16670432 Threshold Effects of Nitric Oxide-induced Toxicity and Cellular Responses in Wild-type and P53-null Human Lymphoblastoid Cells Chemical Research in Toxicology. Mar, 2006 | Pubmed ID: 16544944 A Single Acute Exposure to a Chemotherapeutic Agent Induces Hyper-recombination in Distantly Descendant Cells and in Their Neighbors Oncogene. Jul, 2005 | Pubmed ID: 15856014 Interstrand Crosslink-induced Homologous Recombination Carries an Increased Risk of Deletions and Insertions DNA Repair. May, 2005 | Pubmed ID: 15811631 Delineation of the Chemical Pathways Underlying Nitric Oxide-induced Homologous Recombination in Mammalian Cells Chemistry & Biology. Mar, 2005 | Pubmed ID: 15797220 In Vivo Recombination After Chronic Damage Exposure Falls to Below Spontaneous Levels in "recombomice" Molecular Cancer Research : MCR. Oct, 2004 | Pubmed ID: 15498931 "Recombomice": the Past, Present, and Future of Recombination-detection in Mice DNA Repair. Oct, 2004 | Pubmed ID: 15336621 New Immunoaffinity-LC-MS/MS Methodology Reveals That Aag Null Mice Are Deficient in Their Ability to Clear 1,N6-etheno-deoxyadenosine DNA Lesions from Lung and Liver in Vivo DNA Repair. Mar, 2004 | Pubmed ID: 15177041 Base Excision Repair Intermediates Induce P53-independent Cytotoxic and Genotoxic Responses The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12882965 Spontaneous Mitotic Homologous Recombination at an Enhanced Yellow Fluorescent Protein (EYFP) CDNA Direct Repeat in Transgenic Mice Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12750464 Base Excision Repair and Nucleotide Excision Repair Contribute to the Removal of N-methylpurines from Active Genes DNA Repair. Aug, 2002 | Pubmed ID: 12509290 Nitric Oxide-induced Homologous Recombination in Escherichia Coli is Promoted by DNA Glycosylases Journal of Bacteriology. Jul, 2002 | Pubmed ID: 12057944 CometChip: תפוקה גבוהה 96-ובכן פלטפורמה למדידת נזק לדנ"א בתאי Microarrayed אדם Jing Ge*1, Somsak Prasongtanakij*2, David K. Wood3, David M. Weingeist1, Jessica Fessler1, Panida Navasummrit2, Mathuros Ruchirawat2, Bevin P. Engelward1 1Department of Biological Engineering, Massachusetts Institute of Technology, 2Environmental Toxicology, Chulabhorn Graduate Institute, 3Department of Biomedical Engineering, University of Minnesota JoVE 50607 Bioengineering
CometChip: תפוקה גבוהה 96-ובכן פלטפורמה למדידת נזק לדנ"א בתאי Microarrayed אדם Jing Ge*1, Somsak Prasongtanakij*2, David K. Wood3, David M. Weingeist1, Jessica Fessler1, Panida Navasummrit2, Mathuros Ruchirawat2, Bevin P. Engelward1 1Department of Biological Engineering, Massachusetts Institute of Technology, 2Environmental Toxicology, Chulabhorn Graduate Institute, 3Department of Biomedical Engineering, University of Minnesota JoVE 50607 Bioengineering