Brendan W. Wren

Publications

• Generation of a Tn5 Transposon Library in Haemophilus Parasuis and Analysis by Transposon-directed Insertion-site Sequencing (TraDIS)
  Veterinary Microbiology. Oct, 2013  |   Pubmed ID: 23928120
• Clostridium Difficile Modulates Host Innate Immunity Via Toxin-independent and Dependent Mechanism(s)
  PloS One. 2013  |   Pubmed ID: 23922820
• Development of a Self-replicating Plasmid System for Mycoplasma Hyopneumoniae
  Veterinary Research. 2013  |   Pubmed ID: 23895236
• Gene Content and Diversity of the Loci Encoding Biosynthesis of Capsular Polysaccharides of the 15 Serovar Reference Strains of Haemophilus Parasuis
  Journal of Bacteriology. Sep, 2013  |   Pubmed ID: 23873912
• Bacteria Like Sharing Their Sweets
  Molecular Microbiology. Sep, 2013  |   Pubmed ID: 23844892
• Altered Innate Defenses in the Neonatal Gastrointestinal Tract in Response to Colonization by Neuropathogenic Escherichia Coli
  Infection and Immunity. Sep, 2013  |   Pubmed ID: 23798529
• The Agr Locus Regulates Virulence and Colonization Genes in Clostridium Difficile 027
  Journal of Bacteriology. Aug, 2013  |   Pubmed ID: 23772065
• Improved Bacterial Mutagenesis by High-frequency Allele Exchange, Demonstrated in Clostridium Difficile and Streptococcus Suis
  Applied and Environmental Microbiology. Aug, 2013  |   Pubmed ID: 23728809
• Exploitation of Bacterial N-linked Glycosylation to Develop a Novel Recombinant Glycoconjugate Vaccine Against Francisella Tularensis
  Open Biology. 2013  |   Pubmed ID: 23697804
• Transcriptional Analysis of Temporal Gene Expression in Germinating Clostridium Difficile 630 Endospores
  PloS One. 2013  |   Pubmed ID: 23691138
• Yersinia Enterocolitica Provides the Link Between Thyroid-stimulating Antibodies and Their Germline Counterparts in Graves' Disease
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2013  |   Pubmed ID: 23630351
• Campylobacter Jejuni Lipooligosaccharide Sialylation, Phosphorylation, and Amide/ester Linkage Modifications Fine-tune Human Toll-like Receptor 4 Activation
  The Journal of Biological Chemistry. Jul, 2013  |   Pubmed ID: 23629657
• Characterization of Water and Wildlife Strains As a Subgroup of Campylobacter Jejuni Using DNA Microarrays
  Environmental Microbiology. Aug, 2013  |   Pubmed ID: 23530835
• Escherichia Coli Pathotypes in Pakistan from Consecutive Floods in 2010 and 2011
  The American Journal of Tropical Medicine and Hygiene. Mar, 2013  |   Pubmed ID: 23358642
• Population Biology of Streptococcus Pneumoniae in West Africa: Multilocus Sequence Typing of Serotypes That Exhibit Different Predisposition to Invasive Disease and Carriage
  PloS One. 2013  |   Pubmed ID: 23342041
• Growth Inhibition of Pathogenic Bacteria by Sulfonylurea Herbicides
  Antimicrobial Agents and Chemotherapy. Mar, 2013  |   Pubmed ID: 23263008
• Emergence and Global Spread of Epidemic Healthcare-associated Clostridium Difficile
  Nature Genetics. Jan, 2013  |   Pubmed ID: 23222960
• Gene Function Hypotheses for the Campylobacter Jejuni Glycome Generated by a Logic-based Approach
  Journal of Molecular Biology. Jan, 2013  |   Pubmed ID: 23103756
• Characterisation of Clostridium Difficile Biofilm Formation, a Role for Spo0A
  PloS One. 2012  |   Pubmed ID: 23236376
• Comparative Phylogenomics of Streptococcus Pneumoniae Isolated from Invasive Disease and Nasopharyngeal Carriage from West Africans
  BMC Genomics. 2012  |   Pubmed ID: 23107513
• Campylobacter Jejuni Outer Membrane Vesicles Play an Important Role in Bacterial Interactions with Human Intestinal Epithelial Cells
  Infection and Immunity. Sep, 2012  |   Pubmed ID: 22966047
• Neutrophil Extracellular Traps Exhibit Antibacterial Activity Against Burkholderia Pseudomallei and Are Influenced by Bacterial and Host Factors
  Infection and Immunity. Nov, 2012  |   Pubmed ID: 22927051
• The Continually Evolving Clostridium Difficile Species
  Future Microbiology. Aug, 2012  |   Pubmed ID: 22913354
• Phenotypic and Genotypic Characterizations of Campylobacter Jejuni Isolated from the Broiler Meat Production Process
  Current Microbiology. Oct, 2012  |   Pubmed ID: 22735984
• The Clostridium Difficile Spo0A Gene is a Persistence and Transmission Factor
  Infection and Immunity. Aug, 2012  |   Pubmed ID: 22615253
• Recent Developments in Bacterial Protein Glycan Coupling Technology and Glycoconjugate Vaccine Design
  Journal of Medical Microbiology. Jul, 2012  |   Pubmed ID: 22516134
• Macro and Micro Diversity of Clostridium Difficile Isolates from Diverse Sources and Geographical Locations
  PloS One. 2012  |   Pubmed ID: 22396735
• Characterization of the Structurally Diverse N-linked Glycans of Campylobacter Species
  Journal of Bacteriology. May, 2012  |   Pubmed ID: 22389484
• Increase in Campylobacter Jejuni Invasion of Intestinal Epithelial Cells Under Low-oxygen Coculture Conditions That Reflect the in Vivo Environment
  Infection and Immunity. May, 2012  |   Pubmed ID: 22354027
• Evidence of Yersinia Pestis DNA from Fleas in an Endemic Plague Area of Zambia
  BMC Research Notes. 2012  |   Pubmed ID: 22280795
• Characterization of the Burkholderia Pseudomallei K96243 Capsular Polysaccharide I Coding Region
  Infection and Immunity. Mar, 2012  |   Pubmed ID: 22252864
• Identification of Immunogenic and Virulence-associated Campylobacter Jejuni Proteins
  Clinical and Vaccine Immunology : CVI. Feb, 2012  |   Pubmed ID: 22155767
• BμG@Sbase--a Microbial Gene Expression and Comparative Genomic Database
  Nucleic Acids Research. Jan, 2012  |   Pubmed ID: 21948792
• Emergence of New PCR Ribotypes from the Hypervirulent Clostridium Difficile 027 Lineage
  Journal of Medical Microbiology. Jan, 2012  |   Pubmed ID: 21903827
• The Campylobacter Jejuni NCTC11168 Capsule Prevents Excessive Cytokine Production by Dendritic Cells
  Medical Microbiology and Immunology. May, 2012  |   Pubmed ID: 21863342
• Hypervirulent Clostridium Difficile PCR-ribotypes Exhibit Resistance to Widely Used Disinfectants
  PloS One. 2011  |   Pubmed ID: 22039420
• Bacterial Epidemiology and Biology--lessons from Genome Sequencing
  Genome Biology. 2011  |   Pubmed ID: 22027015
• The Campylobacter Jejuni Transcriptional Regulator Cj1556 Plays a Role in the Oxidative and Aerobic Stress Response and is Important for Bacterial Survival in Vivo
  Journal of Bacteriology. Aug, 2011  |   Pubmed ID: 21642451
• The Analysis of Para-cresol Production and Tolerance in Clostridium Difficile 027 and 012 Strains
  BMC Microbiology. 2011  |   Pubmed ID: 21527013
• Identification and Characterisation of a Novel Adhesin Ifp in Yersinia Pseudotuberculosis
  BMC Microbiology. 2011  |   Pubmed ID: 21527009
• Genomic Variations Define Divergence of Water/wildlife-associated Campylobacter Jejuni Niche Specialists from Common Clonal Complexes
  Environmental Microbiology. Jun, 2011  |   Pubmed ID: 21418497
• Biofilm Development on Caenorhabditis Elegans by Yersinia is Facilitated by Quorum Sensing-dependent Repression of Type III Secretion
  PLoS Pathogens. 2011  |   Pubmed ID: 21253572
• Yersinia Pseudotuberculosis MntH Functions in Intracellular Manganese Accumulation, Which is Essential for Virulence and Survival in Cells Expressing Functional Nramp1
  Microbiology (Reading, England). Apr, 2011  |   Pubmed ID: 21183572
• Effect of Chicken Meat Environment on Gene Expression of Campylobacter Jejuni and Its Relevance to Survival in Food
  International Journal of Food Microbiology. Mar, 2011  |   Pubmed ID: 20858569
• In-depth Genetic Analysis of Clostridium Difficile PCR-ribotype 027 Strains Reveals High Genome Fluidity Including Point Mutations and Inversions
  Gut Microbes. 7, 2010  |   Pubmed ID: 21327033
• Delineation of the Innate and Adaptive T-cell Immune Outcome in the Human Host in Response to Campylobacter Jejuni Infection
  PloS One. 2010  |   Pubmed ID: 21085698
• Glycoproteomics: a Powerful Tool for Characterizing the Diverse Glycoforms of Bacterial Pilins and Flagellins
  Biochemical Society Transactions. Oct, 2010  |   Pubmed ID: 20863304
• Systems Analysis of Bacterial Glycomes
  Biochemical Society Transactions. Oct, 2010  |   Pubmed ID: 20863301
• Liposomal Delivery of P-ialB and P-omp25 DNA Vaccines Improves Immunogenicity but Fails to Provide Full Protection Against B. Melitensis Challenge
  Genetic Vaccines and Therapy. 2010  |   Pubmed ID: 20637091
• Global Transcriptional Profiling of Burkholderia Pseudomallei Under Salt Stress Reveals Differential Effects on the Bsa Type III Secretion System
  BMC Microbiology. 2010  |   Pubmed ID: 20540813
• Administration of Capsule-selective Endosialidase E Minimizes Upregulation of Organ Gene Expression Induced by Experimental Systemic Infection with Escherichia Coli K1
  Microbiology (Reading, England). Jul, 2010  |   Pubmed ID: 20395269
• Evolutionary Dynamics of Clostridium Difficile over Short and Long Time Scales
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010  |   Pubmed ID: 20368420
• Insect Infection Model for Campylobacter Jejuni Reveals That O-methyl Phosphoramidate Has Insecticidal Activity
  The Journal of Infectious Diseases. Mar, 2010  |   Pubmed ID: 20113177
• Simple Sequence Repeats in Helicobacter Canadensis and Their Role in Phase Variable Expression and C-terminal Sequence Switching
  BMC Genomics. 2010  |   Pubmed ID: 20105305
• Steps Toward Broad-spectrum Therapeutics: Discovering Virulence-associated Genes Present in Diverse Human Pathogens
  BMC Genomics. 2009  |   Pubmed ID: 19874620
• Comparative Genome and Phenotypic Analysis of Clostridium Difficile 027 Strains Provides Insight into the Evolution of a Hypervirulent Bacterium
  Genome Biology. 2009  |   Pubmed ID: 19781061
• Recent Advances in Systems Microbiology
  Current Opinion in Microbiology. Oct, 2009  |   Pubmed ID: 19748820
• New Levels of Sophistication in the Transcriptional Landscape of Bacteria
  Genome Biology. 2009  |   Pubmed ID: 19664196
• Antibiotic Treatment of Clostridium Difficile Carrier Mice Triggers a Supershedder State, Spore-mediated Transmission, and Severe Disease in Immunocompromised Hosts
  Infection and Immunity. Sep, 2009  |   Pubmed ID: 19564382
• Clostridium Difficile--a Continually Evolving and Problematic Pathogen
  Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. Dec, 2009  |   Pubmed ID: 19539054
• N-linked Glycosylation in Bacteria: an Unexpected Application
  Future Microbiology. May, 2009  |   Pubmed ID: 19416010
• Galleria Mellonella As an Alternative Infection Model for Yersinia Pseudotuberculosis
  Microbiology (Reading, England). May, 2009  |   Pubmed ID: 19383703
• Campylobacter Jejuni Glycosylation Island Important in Cell Charge, Legionaminic Acid Biosynthesis, and Colonization of Chickens
  Infection and Immunity. Jun, 2009  |   Pubmed ID: 19307210
• YtxR Acts As an Overriding Transcriptional off Switch for the Yersinia Enterocolitica Ysc-Yop Type 3 Secretion System
  Journal of Bacteriology. Jan, 2009  |   Pubmed ID: 19011024
• Development and Application of the Active Surveillance of Pathogens Microarray to Monitor Bacterial Gene Flux
  BMC Microbiology. 2008  |   Pubmed ID: 18844996
• Comparative Analysis of BI/NAP1/027 Hypervirulent Strains Reveals Novel Toxin B-encoding Gene (tcdB) Sequences
  Journal of Medical Microbiology. Jun, 2008  |   Pubmed ID: 18480336
• Microarray Analysis of the Transcriptional Responses of Clostridium Difficile to Environmental and Antibiotic Stress
  Journal of Medical Microbiology. Jun, 2008  |   Pubmed ID: 18480334
• Assessing the Role of P-cresol Tolerance in Clostridium Difficile
  Journal of Medical Microbiology. Jun, 2008  |   Pubmed ID: 18480332
• The Importance of the Rcs Phosphorelay in the Survival and Pathogenesis of the Enteropathogenic Yersiniae
  Microbiology (Reading, England). Apr, 2008  |   Pubmed ID: 18375804
• Campylobacter Jejuni-mediated Disease Pathogenesis: an Update
  Transactions of the Royal Society of Tropical Medicine and Hygiene. Feb, 2008  |   Pubmed ID: 18023831
• Comparative Genome Analyses of the Pathogenic Yersiniae Based on the Genome Sequence of Yersinia Enterocolitica Strain 8081
  Advances in Experimental Medicine and Biology. 2007  |   Pubmed ID: 17966400
• Bacterial Pathogenomics
  Nature. Oct, 2007  |   Pubmed ID: 17943120
• The RovA Regulons of Yersinia Enterocolitica and Yersinia Pestis Are Distinct: Evidence That Many RovA-regulated Genes Were Acquired More Recently Than the Core Genome
  Molecular Microbiology. Oct, 2007  |   Pubmed ID: 17784909
• Deletion of a Previously Uncharacterized Flagellar-hook-length Control Gene FliK Modulates the Sigma54-dependent Regulon in Campylobacter Jejuni
  Microbiology (Reading, England). Sep, 2007  |   Pubmed ID: 17768253
• The Second Century of Campylobacter Research: Recent Advances, New Opportunities and Old Problems
  Current Opinion in Infectious Diseases. Oct, 2007  |   Pubmed ID: 17762786
• Commonality and Biosynthesis of the O-methyl Phosphoramidate Capsule Modification in Campylobacter Jejuni
  The Journal of Biological Chemistry. Sep, 2007  |   Pubmed ID: 17675288
• Re-annotation and Re-analysis of the Campylobacter Jejuni NCTC11168 Genome Sequence
  BMC Genomics. 2007  |   Pubmed ID: 17565669
• A Major Role for Intestinal Epithelial Nucleotide Oligomerization Domain 1 (NOD1) in Eliciting Host Bactericidal Immune Responses to Campylobacter Jejuni
  Cellular Microbiology. Oct, 2007  |   Pubmed ID: 17521327
• The Identification of Two Protective DNA Vaccines from a Panel of Five Plasmid Constructs Encoding Brucella Melitensis 16M Genes
  Vaccine. Jan, 2007  |   Pubmed ID: 17049676
• Clostridium Difficile Comes of Age
  Future Microbiology. Oct, 2006  |   Pubmed ID: 17661635
• The Complete Genome Sequence and Comparative Genome Analysis of the High Pathogenicity Yersinia Enterocolitica Strain 8081
  PLoS Genetics. Dec, 2006  |   Pubmed ID: 17173484
• The Multidrug-resistant Human Pathogen Clostridium Difficile Has a Highly Mobile, Mosaic Genome
  Nature Genetics. Jul, 2006  |   Pubmed ID: 16804543
• Numerical Analysis of DNA Microarray Data of Campylobacter Jejuni Strains Correlated with Survival, Cytolethal Distending Toxin and Haemolysin Analyses
  International Journal of Medical Microbiology : IJMM. Oct, 2006  |   Pubmed ID: 16782402
• Application of Comparative Phylogenomics to Study the Evolution of Yersinia Enterocolitica and to Identify Genetic Differences Relating to Pathogenicity
  Journal of Bacteriology. May, 2006  |   Pubmed ID: 16672618
• Mucosal Immunization with a Urease B DNA Vaccine Induces Innate and Cellular Immune Responses Against Helicobacter Pylori
  Helicobacter. Apr, 2006  |   Pubmed ID: 16579841
• Serotype Differences and Lack of Biofilm Formation Characterize Yersinia Pseudotuberculosis Infection of the Xenopsylla Cheopis Flea Vector of Yersinia Pestis
  Journal of Bacteriology. Feb, 2006  |   Pubmed ID: 16428415
• Intestinal Innate Immunity to Campylobacter Jejuni Results in Induction of Bactericidal Human Beta-defensins 2 and 3
  Infection and Immunity. Nov, 2005  |   Pubmed ID: 16239524
• Comparative Phylogenomics of the Food-borne Pathogen Campylobacter Jejuni Reveals Genetic Markers Predictive of Infection Source
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005  |   Pubmed ID: 16230626
• Comparative Phylogenomics of Pathogenic Bacteria by Microarray Analysis
  Current Opinion in Microbiology. Oct, 2005  |   Pubmed ID: 16125441
• Explorative Multifactor Approach for Investigating Global Survival Mechanisms of Campylobacter Jejuni Under Environmental Conditions
  Applied and Environmental Microbiology. Apr, 2005  |   Pubmed ID: 15812042
• The Campylobacter Jejuni Glycome
  FEMS Microbiology Reviews. Apr, 2005  |   Pubmed ID: 15808749
• Functional Analysis of the Campylobacter Jejuni N-linked Protein Glycosylation Pathway
  Molecular Microbiology. Mar, 2005  |   Pubmed ID: 15752194
• Protein Glycosylation in Bacterial Mucosal Pathogens
  Nature Reviews. Microbiology. Mar, 2005  |   Pubmed ID: 15738950
• Revised Nomenclature of Clostridium Difficile Toxins and Associated Genes
  Journal of Medical Microbiology. Feb, 2005  |   Pubmed ID: 15673503
• The Complete Genome Sequence of Francisella Tularensis, the Causative Agent of Tularemia
  Nature Genetics. Feb, 2005  |   Pubmed ID: 15640799
• Analysis of Campylobacter Jejuni Capsular Loci Reveals Multiple Mechanisms for the Generation of Structural Diversity and the Ability to Form Complex Heptoses
  Molecular Microbiology. Jan, 2005  |   Pubmed ID: 15612919
• Invertebrates As a Source of Emerging Human Pathogens
  Nature Reviews. Microbiology. Oct, 2004  |   Pubmed ID: 15378047
• Adaptation of Campylobacter Jejuni NCTC11168 to High-level Colonization of the Avian Gastrointestinal Tract
  Infection and Immunity. Jul, 2004  |   Pubmed ID: 15213117
• The Yersiniae--a Model Genus to Study the Rapid Evolution of Bacterial Pathogens
  Nature Reviews. Microbiology. Oct, 2003  |   Pubmed ID: 15040180
• Genes to Genetic Immunization: Identification of Bacterial Vaccine Candidates
  Methods (San Diego, Calif.). Nov, 2003  |   Pubmed ID: 14511951
• Application of DNA Microarrays to Study the Evolutionary Genomics of Yersinia Pestis and Yersinia Pseudotuberculosis
  Genome Research. Sep, 2003  |   Pubmed ID: 12952873
• Campylobacter--a Tale of Two Protein Glycosylation Systems
  Trends in Microbiology. May, 2003  |   Pubmed ID: 12781527
• Signature-tagged Mutagenesis of Yersinia Pestis
  Advances in Experimental Medicine and Biology. 2003  |   Pubmed ID: 12756725
• Microarrays for Bacterial Pathogens - Hope or Hype?
  Comparative and Functional Genomics. 2002  |   Pubmed ID: 18629265
• Microarray Analysis of Campylobacter Jejuni: to the Guts of the Problem!
  Comparative and Functional Genomics. 2002  |   Pubmed ID: 18629262
• N-linked Glycosylation in Campylobacter Jejuni and Its Functional Transfer into E. Coli
  Science (New York, N.Y.). Nov, 2002  |   Pubmed ID: 12459590
• Deciphering Tsetse's Secret Partner
  Nature Genetics. Nov, 2002  |   Pubmed ID: 12410225
• Structural Characterization of Lipo-oligosaccharide (LOS) from Yersinia Pestis: Regulation of LOS Structure by the PhoPQ System
  Molecular Microbiology. Jun, 2002  |   Pubmed ID: 12067350
• Helicobacter Pylori Adherence to Gastric Epithelial Cells: a Role for Non-adhesin Virulence Genes
  Journal of Medical Microbiology. Jun, 2002  |   Pubmed ID: 12018657
• Identification of N-acetylgalactosamine-containing Glycoproteins PEB3 and CgpA in Campylobacter Jejuni
  Molecular Microbiology. Jan, 2002  |   Pubmed ID: 11985725
• A Novel Paralogous Gene Family Involved in Phase-variable Flagella-mediated Motility in Campylobacter Jejuni
  Microbiology (Reading, England). Feb, 2002  |   Pubmed ID: 11832511