In JoVE (1)
Other Publications (1)
Articles by Brendon W. Kent in JoVE
Automated Visual Cognitive Tasks for Recording Neural Activity Using a Floor Projection Maze Tara K. Jacobson*1, Jonathan W. Ho*1, Brendon W. Kent1, Fang-Chi Yang1, Rebecca D. Burwell1,2 1Department of Cognitive, Linguistic & Psychological Sciences, Brown University, 2Department of Neuroscience, Brown University We describe protocols for training rats for chronic electrophysiological recordings in fully automated cognitive tasks on a Floor Projection Maze.
Other articles by Brendon W. Kent on PubMed
Deficient Visual Sensitivity in Schizotypal Personality Disorder Schizophrenia Research. Apr, 2011 | Pubmed ID: 20541911 Schizotypal personality disorder is a personality disorder in the schizophrenia spectrum, sharing genetic and neurobiologic characteristics with schizophrenia. Visual contrast detection, found to be abnormal in chronic schizophrenia, was investigated in schizotypal personality disorder (SPD). Since dopamine in the retina enhances visual contrast detection and SPD patients have relatively reduced dopaminergic activity in the brain compared to schizophrenia patients, it was hypothesized that SPD patients would have decreased to normal contrast sensitivity. Twenty-one subjects with DSM-IV diagnosed SPD, 18 healthy controls, and 12 subjects with a personality disorder unrelated to schizophrenia (OPD) were evaluated for contrast detection using a sinusoidal grating presented at varying temporal frequencies. Subjects also were evaluated neuropsychologically using several standardized neurocognitive tests. A significant effect of subject group was found on the contrast detection threshold (p