Caroline A. Owen Division of Pulmonary and Critical Care Medicine Brigham and Women's Hospital - Harvard Medical School Biography Publications Institution JoVE Articles Caroline A. Owen has not added a biography. If you are Caroline A. Owen and would like to personalize this page please email our Author Liaison for assistance. Publications A Novel Nonhuman Primate Model of Cigarette Smoke-Induced Airway Disease The American Journal of Pathology. Dec, 2014 | Pubmed ID: 25542772 Folliculin Regulates Cell-cell Adhesion, AMPK, and MTORC1 in a Cell-type-specific Manner in Lung-derived Cells Physiological Reports. Aug, 2014 | Pubmed ID: 25121506 Mitophagy-dependent Necroptosis Contributes to the Pathogenesis of COPD The Journal of Clinical Investigation. Sep, 2014 | Pubmed ID: 25083992 ADAM9 is a Novel Product of Polymorphonuclear Neutrophils: Regulation of Expression and Contributions to Extracellular Matrix Protein Degradation During Acute Lung Injury Journal of Immunology (Baltimore, Md. : 1950). Sep, 2014 | Pubmed ID: 25063875 Effects of Sex Hormones on Bronchial Reactivity During the Menstrual Cycle BMC Pulmonary Medicine. 2014 | Pubmed ID: 24984749 Idiopathic Pulmonary Fibrosis and Coronary Artery Disease Multidisciplinary Respiratory Medicine. 2014 | Pubmed ID: 24976970 Mononuclear Phagocytes and Airway Epithelial Cells: Novel Sources of Matrix Metalloproteinase-8 (MMP-8) in Patients with Idiopathic Pulmonary Fibrosis PloS One. 2014 | Pubmed ID: 24828408 Functional Characterization of Polymorphisms in the Peptidase Inhibitor 3 (elafin) Gene and Validation of Their Contribution to Risk of Acute Respiratory Distress Syndrome American Journal of Respiratory Cell and Molecular Biology. Aug, 2014 | Pubmed ID: 24617927 Rapid Lung Function Decline in Smokers is a Risk Factor for COPD and is Attenuated by Angiotensin-converting Enzyme Inhibitor Use Chest. Apr, 2014 | Pubmed ID: 24008986 Comparison of Arterial and Venous Blood Biomarker Levels in Chronic Obstructive Pulmonary Disease F1000Research. 2013 | Pubmed ID: 24555057 The Club Cell and Its Protein, CC16: Time to Shine The Lancet. Respiratory Medicine. Dec, 2013 | Pubmed ID: 24461745 Histone Deacetylase 6-mediated Selective Autophagy Regulates COPD-associated Cilia Dysfunction The Journal of Clinical Investigation. Dec, 2013 | Pubmed ID: 24200693 Adam8 Limits the Development of Allergic Airway Inflammation in Mice Journal of Immunology (Baltimore, Md. : 1950). Jun, 2013 | Pubmed ID: 23670189 Adipose-derived Stem Cells Weigh in As Novel Therapeutics for Acute Lung Injury Stem Cell Research & Therapy. 2013 | Pubmed ID: 23510703 Profibrotic Activities for Matrix Metalloproteinase-8 During Bleomycin-mediated Lung Injury Journal of Immunology (Baltimore, Md. : 1950). Apr, 2013 | Pubmed ID: 23487425 The Role of Systemic Inflammatory Biomarkers to Predict Mortality in Chronic Obstructive Pulmonary Disease Expert Review of Respiratory Medicine. Feb, 2013 | Pubmed ID: 23362815 Selenoprotein N Deficiency in Mice is Associated with Abnormal Lung Development FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2013 | Pubmed ID: 23325319 Inflammation in COPD: Implications for Management The American Journal of Medicine. Dec, 2012 | Pubmed ID: 23164484 Interleukin-18: the Master Regulator Driving Destructive and Remodeling Processes in the Lungs of Patients with Chronic Obstructive Pulmonary Disease? American Journal of Respiratory and Critical Care Medicine. Jun, 2012 | Pubmed ID: 22661518 Genetically Manipulated Mouse Models of Lung Disease: Potential and Pitfalls American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2011 | Pubmed ID: 22198907 Polymorphonuclear Neutrophils Move into the Fast Lane in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. May, 2011 | Pubmed ID: 21531949 Matrix Metalloproteinases: All the RAGE in the Acute Respiratory Distress Syndrome American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2011 | Pubmed ID: 21296893 Matrix Metalloproteinase-8 Inactivates Macrophage Inflammatory Protein-1 Alpha to Reduce Acute Lung Inflammation and Injury in Mice Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20042585 ADAM8: a New Therapeutic Target for Asthma Expert Opinion on Therapeutic Targets. May, 2009 | Pubmed ID: 19397475 Roles for Proteinases in the Pathogenesis of Chronic Obstructive Pulmonary Disease International Journal of Chronic Obstructive Pulmonary Disease. 2008 | Pubmed ID: 18686734 Leukocyte Cell Surface Proteinases: Regulation of Expression, Functions, and Mechanisms of Surface Localization The International Journal of Biochemistry & Cell Biology. 2008 | Pubmed ID: 18329945 CD8+ T Cells Are Required for Inflammation and Destruction in Cigarette Smoke-induced Emphysema in Mice Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17548647 The Sulfate Groups of Chondroitin Sulfate- and Heparan Sulfate-containing Proteoglycans in Neutrophil Plasma Membranes Are Novel Binding Sites for Human Leukocyte Elastase and Cathepsin G The Journal of Biological Chemistry. May, 2007 | Pubmed ID: 17384412 Induction of the Plasminogen Activator System by Mechanical Stimulation of Human Bronchial Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. Dec, 2006 | Pubmed ID: 16794260 Proteinases and Oxidants As Targets in the Treatment of Chronic Obstructive Pulmonary Disease Proceedings of the American Thoracic Society. 2005 | Pubmed ID: 16267366 Membrane-bound Matrix Metalloproteinase-8 on Activated Polymorphonuclear Cells is a Potent, Tissue Inhibitor of Metalloproteinase-resistant Collagenase and Serpinase Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15187163 Neutrophil Elastase in Human Atherosclerotic Plaques: Production by Macrophages Circulation. Jun, 2003 | Pubmed ID: 12771009 Inducible Expression of Tissue Inhibitor of Metalloproteinases-resistant Matrix Metalloproteinase-9 on the Cell Surface of Neutrophils American Journal of Respiratory Cell and Molecular Biology. Sep, 2003 | Pubmed ID: 12663332 ADAM-33 Surfaces As an Asthma Gene The New England Journal of Medicine. Sep, 2002 | Pubmed ID: 12239266 सिगरेट के धुएं में उजागर चूहे में फेफड़े के वातस्फीति और लघु श्वासनली remodeling के स्वचालित माप Maria E. Laucho-Contreras1, Katherine L. Taylor1, Ravi Mahadeva2, Steve S. Boukedes3, Caroline A. Owen1,4 1Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital - Harvard Medical School, 2Department of Respiratory Medicine, University of Cambridge - Addenbrooke's Hospital, 3Lung Transplant Program, Brigham and Women's Hospital - Harvard Medical School, 4COPD and IPF Programs, Lovelace Respiratory Research Institute Medicine
सिगरेट के धुएं में उजागर चूहे में फेफड़े के वातस्फीति और लघु श्वासनली remodeling के स्वचालित माप Maria E. Laucho-Contreras1, Katherine L. Taylor1, Ravi Mahadeva2, Steve S. Boukedes3, Caroline A. Owen1,4 1Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital - Harvard Medical School, 2Department of Respiratory Medicine, University of Cambridge - Addenbrooke's Hospital, 3Lung Transplant Program, Brigham and Women's Hospital - Harvard Medical School, 4COPD and IPF Programs, Lovelace Respiratory Research Institute Medicine