In JoVE (1)
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Articles by Carolyn Xue in JoVE
Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells Qiao Li1, Lin Lu1, Huimin Tao1, Carolyn Xue1, Seagal Teitz-Tennenbaum2, John H. Owen3, Jeffrey S Moyer3, Mark E.P. Prince3, Alfred E. Chang1, Max S. Wicha2 1Department of Surgery, University of Michigan, 2Department of Internal Medicine, University of Michigan, 3Department of Otolaryngology, University of Michigan Evaluated in syngeneic immunocompetent hosts, cancer stem cell (CSC) based dendritic cell (DC) vaccine demonstrated significantly higher antitumor immunity than traditional DC vaccines pulsed with heterogeneous bulk tumor cells.