Changyu Zheng Molecular Physiology and Therapeutics Branch National Institute of Dental and Craniofacial Research, NIH, DHHS Biography Publications Institution JoVE Articles Changyu Zheng has not added a biography. If you are Changyu Zheng and would like to personalize this page please email our Author Liaison for assistance. Publications Effects of Human Vascular Endothelial Growth Factor on Reparative Dentin Formation Molecular Medicine Reports. Jan, 2016 | Pubmed ID: 26647730 Essential Role of Carbonic Anhydrase XII in Secretory Gland Fluid and HCO3 (-) Secretion Revealed by Disease Causing Human Mutation The Journal of Physiology. Dec, 2015 | Pubmed ID: 26486891 Inhibition of Autophagy by 3-MA Enhances IL-24-induced Apoptosis in Human Oral Squamous Cell Carcinoma Cells Journal of Experimental & Clinical Cancer Research : CR. 2015 | Pubmed ID: 26361755 Advances in Salivary Gland Gene Therapy - Oral and Systemic Implications Expert Opinion on Biological Therapy. 2015 | Pubmed ID: 26149284 STIM2 Enhances Receptor-stimulated Ca²⁺ Signaling by Promoting Recruitment of STIM1 to the Endoplasmic Reticulum-plasma Membrane Junctions Science Signaling. Jan, 2015 | Pubmed ID: 25587190 Assessment of Transfection of AdCMV-EGFP to Rat Submandibular Gland Cells Cell Biochemistry and Biophysics. Jan, 2015 | Pubmed ID: 25108736 Integration of the Hybrid Adenoretroviral Vector AdLTR-luc Involves Both MoMLV Elements Flanking the Transgene International Journal of Medical Sciences. 2014 | Pubmed ID: 24936143 Efficiently Engineered Cell Sheet Using a Complex of Polyethylenimine-alginate Nanocomposites Plus Bone Morphogenetic Protein 2 Gene to Promote New Bone Formation International Journal of Nanomedicine. 2014 | Pubmed ID: 24855355 All Human EF1α Promoters Are Not Equal: Markedly Affect Gene Expression in Constructs from Different Sources International Journal of Medical Sciences. 2014 | Pubmed ID: 24688302 Toxicity and Biodistribution of the Serotype 2 Recombinant Adeno-associated Viral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Mouse Parotid Gland PloS One. 2014 | Pubmed ID: 24667436 Antitumor Effect of TRAIL on Oral Squamous Cell Carcinoma Using Magnetic Nanoparticle-mediated Gene Expression Cell Biochemistry and Biophysics. Jul, 2014 | Pubmed ID: 24563116 Enhancement of Osteoinduction by Continual Simvastatin Release from Poly(lactic-co-glycolic Acid)-hydroxyapatite-simvastatin Nano-fibrous Scaffold Journal of Biomedical Nanotechnology. Nov, 2013 | Pubmed ID: 24059091 Using Poly(lactic-co-glycolic Acid) Microspheres to Encapsulate Plasmid of Bone Morphogenetic Protein 2/polyethylenimine Nanoparticles to Promote Bone Formation in Vitro and in Vivo International Journal of Nanomedicine. 2013 | Pubmed ID: 23990717 MiR-150 Promotes Renal Fibrosis in Lupus Nephritis by Downregulating SOCS1 Journal of the American Society of Nephrology : JASN. Jun, 2013 | Pubmed ID: 23723424 Expression and Secretion of Human Proinsulin-B10 from Mouse Salivary Glands: Implications for the Treatment of Type I Diabetes Mellitus PloS One. 2013 | Pubmed ID: 23554999 Irbit Mediates Synergy Between Ca(2+) and CAMP Signaling Pathways During Epithelial Transport in Mice Gastroenterology. Jul, 2013 | Pubmed ID: 23542070 Loss of TRPM2 Function Protects Against Irradiation-induced Salivary Gland Dysfunction Nature Communications. 2013 | Pubmed ID: 23443543 Recovery of Radiation-induced Dry Eye and Corneal Damage by Pretreatment with Adenoviral Vector-mediated Transfer of Erythropoietin to the Salivary Glands in Mice Human Gene Therapy. Apr, 2013 | Pubmed ID: 23402345 Impairment of TRPC1-STIM1 Channel Assembly and AQP5 Translocation Compromise Agonist-stimulated Fluid Secretion in Mice Lacking Caveolin1 Journal of Cell Science. Jan, 2013 | Pubmed ID: 23203809 Antitumor Effect of Human TRAIL on Adenoid Cystic Carcinoma Using Magnetic Nanoparticle-mediated Gene Expression Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2013 | Pubmed ID: 22633896 Early Responses to Adenoviral-mediated Transfer of the Aquaporin-1 CDNA for Radiation-induced Salivary Hypofunction Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23129637 A Novel Hybrid Adenoretroviral Vector with More Extensive E3 Deletion Extends Transgene Expression in Submandibular Glands Human Gene Therapy Methods. Jun, 2012 | Pubmed ID: 22817829 Sustained Exendin-4 Secretion Through Gene Therapy Targeting Salivary Glands in Two Different Rodent Models of Obesity/type 2 Diabetes PloS One. 2012 | Pubmed ID: 22808093 Sialin (SLC17A5) Functions As a Nitrate Transporter in the Plasma Membrane Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22778404 Pharmacological Protection from Radiation ± Cisplatin-induced Oral Mucositis International Journal of Radiation Oncology, Biology, Physics. Dec, 2011 | Pubmed ID: 22197226 Assessment of the Safety and Biodistribution of a Regulated AAV2 Gene Transfer Vector After Delivery to Murine Submandibular Glands Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2011 | Pubmed ID: 21625005 Prevention of Radiation-induced Salivary Hypofunction Following HKGF Gene Delivery to Murine Submandibular Glands Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21367751 Effect of Irradiation on Microvascular Endothelial Cells of Parotid Glands in the Miniature Pig International Journal of Radiation Oncology, Biology, Physics. Nov, 2010 | Pubmed ID: 20832188 Gene Therapy of Salivary Diseases Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20717774 Systemic Delivery of Bioactive Glucagon-like Peptide 1 After Adenoviral-mediated Gene Transfer in the Murine Salivary Gland Endocrinology. Sep, 2010 | Pubmed ID: 20610567 Salivary Epithelial Cells: an Unassuming Target Site for Gene Therapeutics The International Journal of Biochemistry & Cell Biology. Jun, 2010 | Pubmed ID: 20219693 Conditional Overexpression of TGF-beta1 Disrupts Mouse Salivary Gland Development and Function Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2010 | Pubmed ID: 20142803 Production and Sorting of Transgenic, Modified Human Parathyroid Hormone in Vivo in Rat Salivary Glands Biochemical and Biophysical Research Communications. Jan, 2010 | Pubmed ID: 19944067 Transient Detection of E1-containing Adenovirus in Saliva After the Delivery of a First-generation Adenoviral Vector to Human Parotid Gland The Journal of Gene Medicine. Jan, 2010 | Pubmed ID: 19941317 Development of a Gene Transfer-based Treatment for Radiation-induced Salivary Hypofunction Oral Oncology. Jan, 2010 | Pubmed ID: 19892587 Adenoviral Mediated Transduction of Adenoid Cystic Carcinoma by Human TRAIL Gene Driven with HTERT Tumor Specific Promoter Induces Apoptosis Cancer Biology & Therapy. May, 2009 | Pubmed ID: 19587531 Prevention of Radiation-induced Oral Mucositis After Adenoviral Vector-mediated Transfer of the Keratinocyte Growth Factor CDNA to Mouse Submandibular Glands Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009 | Pubmed ID: 19584147 In Vivo Secretion of the Mouse Immunoglobulin G Fc Fragment from Rat Submandibular Glands The Journal of Gene Medicine. Jul, 2009 | Pubmed ID: 19424985 Long-term Transduction of Miniature Pig Parotid Glands Using Serotype 2 Adeno-associated Viral Vectors The Journal of Gene Medicine. Jun, 2009 | Pubmed ID: 19326368 Aquaporin-1 Gene Transfer to Correct Radiation-induced Salivary Hypofunction Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19096789 Sorting of Transgenic Secretory Proteins in Rhesus Macaque Parotid Glands After Adenovirus-mediated Gene Transfer Human Gene Therapy. Dec, 2008 | Pubmed ID: 18764738 Sorting of Growth Hormone-erythropoietin Fusion Proteins in Rat Salivary Glands Biochemical and Biophysical Research Communications. Aug, 2008 | Pubmed ID: 18544341 Evaluation of Promoters for Use in Tissue-specific Gene Delivery Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18470647 Extended Transgene Expression from a Nonintegrating Adenoviral Vector Containing Retroviral Elements Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2008 | Pubmed ID: 18388914 Sorting Behavior of a Transgenic Erythropoietin-growth Hormone Fusion Protein in Murine Salivary Glands Human Gene Therapy. Mar, 2008 | Pubmed ID: 18303958 Adeno-associated Virus Type 12 (AAV12): a Novel AAV Serotype with Sialic Acid- and Heparan Sulfate Proteoglycan-independent Transduction Activity Journal of Virology. Feb, 2008 | Pubmed ID: 18045941 Sorting of Transgenic Secretory Proteins in Miniature Pig Parotid Glands Following Adenoviral-mediated Gene Transfer The Journal of Gene Medicine. Sep, 2007 | Pubmed ID: 17654745 Female Mice Are More Susceptible to Developing Inflammatory Disorders Due to Impaired Transforming Growth Factor Beta Signaling in Salivary Glands Arthritis and Rheumatism. Jun, 2007 | Pubmed ID: 17530708 Adeno-associated Virus Serotype 2-mediated Gene Transfer to the Parotid Glands of Nonhuman Primates Human Gene Therapy. Feb, 2007 | Pubmed ID: 17328682 Toxicity and Biodistribution of a First-generation Recombinant Adenoviral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Rat Submandibular Gland Human Gene Therapy. Nov, 2006 | Pubmed ID: 17069536 Transfer of the AQP1 CDNA for the Correction of Radiation-induced Salivary Hypofunction Biochimica Et Biophysica Acta. Aug, 2006 | Pubmed ID: 16368071 Vaccine of Engineered Tumor Cells Secreting Stromal Cell-derived Factor-1 Induces T-cell Dependent Antitumor Responses Cancer Biotherapy & Radiopharmaceuticals. Aug, 2005 | Pubmed ID: 16114988 Evaluation of Viral and Mammalian Promoters for Use in Gene Delivery to Salivary Glands Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2005 | Pubmed ID: 16099414 Significant Tumor Regression Induced by Microencapsulation of Recombinant Tumor Cells Secreting Fusion Protein Cancer Biotherapy & Radiopharmaceuticals. Jun, 2005 | Pubmed ID: 15989471 Salivary Glands As a Potential Gene Transfer Target for Gene Therapeutics of Some Monogenetic Endocrine Disorders The Journal of Endocrinology. Jun, 2005 | Pubmed ID: 15930162 Intratumoral Administration of Immature Dendritic Cells Following the Adenovirus Vector Encoding CD40 Ligand Elicits Significant Regression of Established Myeloma Cancer Gene Therapy. Feb, 2005 | Pubmed ID: 15565183 Combined Alpha Tumor Necrosis Factor Gene Therapy and Engineered Dendritic Cell Vaccine in Combating Well-established Tumors The Journal of Gene Medicine. Aug, 2004 | Pubmed ID: 15293344 Reengineered Salivary Glands Are Stable Endogenous Bioreactors for Systemic Gene Therapeutics Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14978265 Advances in Vector-mediated Gene Transfer Immunology Letters. Dec, 2003 | Pubmed ID: 14687716 Inclusion of Moloney Murine Leukemia Virus Elements Upstream of the Transgene Cassette in an E1-deleted Adenovirus Leads to an Unusual Genomic Integration in Epithelial Cells Virology. Sep, 2003 | Pubmed ID: 12954213 Distribution and Toxicity Resulting from Adenoviral Vector Administration to a Single Salivary Gland in Adult Rats Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. Aug, 2003 | Pubmed ID: 12846788 Integration Efficiency of a Hybrid Adenoretroviral Vector Biochemical and Biophysical Research Communications. Jan, 2003 | Pubmed ID: 12480529 Gene Transfer to Salivary Glands International Review of Cytology. 2002 | Pubmed ID: 11837896 Long-term Expression After Infection by the Hybrid Vector AdLTR-luc is from Integrated Transgene Biochemical and Biophysical Research Communications. Feb, 2002 | Pubmed ID: 11829458 Retroductal अवअधोहनुज ग्रंथि टपकाना और लार hypofunction की एक चूहे मॉडल में स्थानीय खंडित विकिरण Renjith Parameswaran Nair1, Changyu Zheng2, Gulshan Sunavala-Dossabhoy1 1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS Medicine व्हार्टन वाहिनी के माध्यम से माउस अवअधोहनुज लार ग्रंथि की Cannulation Yusuke Kuriki1, Younan Liu1, Dengsheng Xia1, Eva M. Gjerde1, Saeed Khalili1, Brennan Mui1, Changyu Zheng2, Simon D. Tran1 1Faculty of Dentistry, McGill University, 2National Institutes of Health, Bethesda, MD, USA JoVE 3074 Medicine
Retroductal अवअधोहनुज ग्रंथि टपकाना और लार hypofunction की एक चूहे मॉडल में स्थानीय खंडित विकिरण Renjith Parameswaran Nair1, Changyu Zheng2, Gulshan Sunavala-Dossabhoy1 1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS Medicine
व्हार्टन वाहिनी के माध्यम से माउस अवअधोहनुज लार ग्रंथि की Cannulation Yusuke Kuriki1, Younan Liu1, Dengsheng Xia1, Eva M. Gjerde1, Saeed Khalili1, Brennan Mui1, Changyu Zheng2, Simon D. Tran1 1Faculty of Dentistry, McGill University, 2National Institutes of Health, Bethesda, MD, USA JoVE 3074 Medicine
