Charles D. Stiles

Publications

• Of Brains and Blood: Developmental Origins of Glioma Diversity?
  Cancer Cell. Oct, 2015  |   Pubmed ID: 26461085
• An Amino Terminal Phosphorylation Motif Regulates Intranuclear Compartmentalization of Olig2 in Neural Progenitor Cells
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2014  |   Pubmed ID: 24948806
• Olig1 Function is Required to Repress Dlx1/2 and Interneuron Production in Mammalian Brain
  Neuron. Feb, 2014  |   Pubmed ID: 24507192
• New Progenitors NESTIN(g) in the EGL
  Nature Neuroscience. Dec, 2013  |   Pubmed ID: 24270268
• Molecular Imaging of Drug Transit Through the Blood-brain Barrier with MALDI Mass Spectrometry Imaging
  Scientific Reports. 2013  |   Pubmed ID: 24091529
• Genomic Analysis of Diffuse Pediatric Low-grade Gliomas Identifies Recurrent Oncogenic Truncating Rearrangements in the Transcription Factor MYBL1
  Proceedings of the National Academy of Sciences of the United States of America. May, 2013  |   Pubmed ID: 23633565
• Separated at Birth? The Functional and Molecular Divergence of OLIG1 and OLIG2
  Nature Reviews. Neuroscience. Dec, 2012  |   Pubmed ID: 23165259
• Asleep at the Switch: MEK Kinases Control Transit to Gliogenesis in Developing Cortex
  Neuron. Sep, 2012  |   Pubmed ID: 22998861
• Prospective, High-throughput Molecular Profiling of Human Gliomas
  Journal of Neuro-oncology. Jul, 2012  |   Pubmed ID: 22821383
• Identification of Molecular Compartments and Genetic Circuitry in the Developing Mammalian Kidney
  Development (Cambridge, England). May, 2012  |   Pubmed ID: 22510988
• Detection of KIAA1549-BRAF Fusion Transcripts in Formalin-fixed Paraffin-embedded Pediatric Low-grade Gliomas
  The Journal of Molecular Diagnostics : JMD. Nov, 2011  |   Pubmed ID: 21884820
• Report from the Fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop
  Neuro-oncology. Jul, 2011  |   Pubmed ID: 21727208
• The Central Nervous System-restricted Transcription Factor Olig2 Opposes P53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma
  Cancer Cell. Mar, 2011  |   Pubmed ID: 21397859
• Phosphorylation State of Olig2 Regulates Proliferation of Neural Progenitors
  Neuron. Mar, 2011  |   Pubmed ID: 21382551
• Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples
  PloS One. 2009  |   Pubmed ID: 19924296
• A Genome-wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2009  |   Pubmed ID: 19741146
• Phase II Study of Imatinib Mesylate for Recurrent Meningiomas (North American Brain Tumor Consortium Study 01-08)
  Neuro-oncology. Dec, 2009  |   Pubmed ID: 19293394
• Glioma Stem Cells: a Midterm Exam
  Neuron. Jun, 2008  |   Pubmed ID: 18579075
• Molecular Pathogenesis of Adult Brain Tumors and the Role of Stem Cells
  Neurologic Clinics. Nov, 2007  |   Pubmed ID: 17964020
• "Smad"eningly Erratic: Target Gene Methylation Determines Whether TGFbeta Promotes or Suppresses Malignant Glioma
  Developmental Cell. Mar, 2007  |   Pubmed ID: 17336898
• Olig2-regulated Lineage-restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
  Neuron. Feb, 2007  |   Pubmed ID: 17296553
• The Bad Seed: PDGF Receptors Link Adult Neural Progenitors to Glioma Stem Cells
  Neuron. Jul, 2006  |   Pubmed ID: 16846849
• Development of NG2 Neural Progenitor Cells Requires Olig Gene Function
  Proceedings of the National Academy of Sciences of the United States of America. May, 2006  |   Pubmed ID: 16682644
• Evidence for Motoneuron Lineage-specific Regulation of Olig2 in the Vertebrate Neural Tube
  Developmental Biology. Apr, 2006  |   Pubmed ID: 16469306
• Targeted Molecular Therapy of Malignant Gliomas
  Current Oncology Reports. Jan, 2006  |   Pubmed ID: 16464405
• Novel Pheochromocytoma Susceptibility Loci Identified by Integrative Genomics
  Cancer Research. Nov, 2005  |   Pubmed ID: 16266984
• A HIF1alpha Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas
  PLoS Genetics. Jul, 2005  |   Pubmed ID: 16103922
• A Genome-wide in Situ Hybridization Map of RNA-binding Proteins Reveals Anatomically Restricted Expression in the Developing Mouse Brain
  BMC Developmental Biology. 2005  |   Pubmed ID: 16033648
• Targeted Molecular Therapy of Malignant Gliomas
  Current Neurology and Neuroscience Reports. May, 2005  |   Pubmed ID: 15865884
• Distinct Temporal Genetic Signatures of Neurogenic and Gliogenic Cues in Cortical Stem Cell Cultures
  Journal of Neurobiology. Jan, 2005  |   Pubmed ID: 15389679
• Mouse Brain Organization Revealed Through Direct Genome-scale TF Expression Analysis
  Science (New York, N.Y.). Dec, 2004  |   Pubmed ID: 15618518
• BHLH Transcription Factor Olig1 is Required to Repair Demyelinated Lesions in the CNS
  Science (New York, N.Y.). Dec, 2004  |   Pubmed ID: 15604411
• The Oligodendroglial Lineage Marker OLIG2 is Universally Expressed in Diffuse Gliomas
  Journal of Neuropathology and Experimental Neurology. May, 2004  |   Pubmed ID: 15198128
• Expression of the Guanine Nucleotide Exchange Factor, Mr-gef, is Regulated During the Differentiation of Specific Subsets of Telencephalic Neurons
  Brain Research. Developmental Brain Research. Dec, 2003  |   Pubmed ID: 14643017
• Lost in Space: Misregulated Positional Cues Create Tripotent Neural Progenitors in Cell Culture
  Neuron. Oct, 2003  |   Pubmed ID: 14642266
• Cross-repressive Interaction of the Olig2 and Nkx2.2 Transcription Factors in Developing Neural Tube Associated with Formation of a Specific Physical Complex
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003  |   Pubmed ID: 14573534
• Basic Helix-loop-helix Factors in Cortical Development
  Neuron. Jul, 2003  |   Pubmed ID: 12848929
• High-resolution Imaging Demonstrates Dynein-based Vesicular Transport of Activated Trk Receptors
  Journal of Neurobiology. Jun, 2002  |   Pubmed ID: 12150505
• Molecular Mechanisms Controlling Cortical Gliogenesis
  Current Opinion in Neurobiology. Jun, 2002  |   Pubmed ID: 12049929
• Common Developmental Requirement for Olig Function Indicates a Motor Neuron/oligodendrocyte Connection
  Cell. Apr, 2002  |   Pubmed ID: 11955448