Ching-Kang Chen Department of Ophthalmology Baylor College of Medicine Biography Publications Institution JoVE Articles Ching-Kang Chen has not added a biography. If you are Ching-Kang Chen and would like to personalize this page please email our Author Liaison for assistance. Publications A Novel Retinal Oscillation Mechanism in an Autosomal Dominant Photoreceptor Degeneration Mouse Model Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26793064 RGS Protein Regulation of Phototransduction Progress in Molecular Biology and Translational Science. 2015 | Pubmed ID: 26123301 Rhodopsin Kinase and Recoverin Modulate Phosphodiesterase During Mouse Photoreceptor Light Adaptation The Journal of General Physiology. Mar, 2015 | Pubmed ID: 25667411 Retinal Cone Photoreceptors Require Phosducin-like Protein 1 for G Protein Complex Assembly and Signaling PloS One. 2015 | Pubmed ID: 25659125 Cannabinoid Receptor-interacting Protein 1a Modulates CB1 Receptor Signaling and Regulation Molecular Pharmacology. Apr, 2015 | Pubmed ID: 25657338 Visual Defects in a Mouse Model of Fetal Alcohol Spectrum Disorder Frontiers in Pediatrics. 2014 | Pubmed ID: 25346924 G Protein Beta 5 is Targeted to D2-dopamine Receptor-containing Biochemical Compartments and Blocks Dopamine-dependent Receptor Internalization PloS One. 2014 | Pubmed ID: 25162404 Phosducin-like Protein 1 is Essential for G-protein Assembly and Signaling in Retinal Rod Photoreceptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2013 | Pubmed ID: 23637185 Light-induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors PloS One. 2013 | Pubmed ID: 23555598 Role of ELOVL4 and Very Long-chain Polyunsaturated Fatty Acids in Mouse Models of Stargardt Type 3 Retinal Degeneration Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23479632 Modulation of Mouse Rod Response Decay by Rhodopsin Kinase and Recoverin The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23136436 The Relationship Between Slow Photoresponse Recovery Rate and Temporal Resolution of Vision The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2012 | Pubmed ID: 23055507 Defective Retinal Depolarizing Bipolar Cells in Regulators of G Protein Signaling (RGS) 7 and 11 Double Null Mice The Journal of Biological Chemistry. Apr, 2012 | Pubmed ID: 22371490 Modulation of CREB in the Dorsal Lateral Geniculate Nucleus of Dark-reared Mice Neural Plasticity. 2012 | Pubmed ID: 22292123 Knockout of G Protein β5 Impairs Brain Development and Causes Multiple Neurologic Abnormalities in Mice Journal of Neurochemistry. Nov, 2011 | Pubmed ID: 21883221 Nicotinic Excitatory Postsynaptic Potentials in Hippocampal CA1 Interneurons Are Predominantly Mediated by Nicotinic Receptors That Contain α4 and β2 Subunits Neuropharmacology. Dec, 2011 | Pubmed ID: 21878344 Stab äußere Segment Retinol-Formation Ist Unabhängig Von Abca4, Arrestin, Rhodopsin-Kinase Und Rhodopsin-Palmitylation Investigative Ophthalmology & Visual Science. May, 2011 | Pubmed ID: 21398289 RGS6, Ein Modulator Der Parasympathische Aktivierung Im Herzen Circulation Research. Nov, 2010 | Pubmed ID: 20864673 Deletion of GRK1 Causes Retina Degeneration Through a Transducin-independent Mechanism The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20164334 Background Light Produces a Recoverin-dependent Modulation of Activated-rhodopsin Lifetime in Mouse Rods The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20107049 Functional Redundancy of R7 RGS Proteins in ON-bipolar Cell Dendrites Investigative Ophthalmology & Visual Science. Feb, 2010 | Pubmed ID: 19797210 The Role of Gβ5 in Vision Progress in Molecular Biology and Translational Science. 2009 | Pubmed ID: 20374718 Trafficking of Membrane Proteins to Cone but Not Rod Outer Segments is Dependent on Heterotrimeric Kinesin-II The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19906976 Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility Molecular Biology of the Cell. Dec, 2008 | Pubmed ID: 18843048 Molecular Architecture of Galphao and the Structural Basis for RGS16-mediated Deactivation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008 | Pubmed ID: 18434540 Sphingosin-1-Phosphat Und Endothelin-1 Veranlassen Den Ausdruck Des Rgs16 Proteins in Kardialen Myozyten Durch Transkriptionelle Aktivierung Des Rgs16-Gens Naunyn-Schmiedeberg's Archives of Pharmacology. Jan, 2008 | Pubmed ID: 18046543 Gbeta5 is Required for Normal Light Responses and Morphology of Retinal ON-bipolar Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2007 | Pubmed ID: 18094259 Expression and Localization of RGS9-2/G 5/R7BP Complex in Vivo is Set by Dynamic Control of Its Constitutive Degradation by Cellular Cysteine Proteases The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2007 | Pubmed ID: 18094251 Subunit Dissociation and Diffusion Determine the Subcellular Localization of Rod and Cone Transducins The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17507570 Transducin Translokation in Stangen Wird Durch Sättigung Des Komplexes GTPase-Aktivierung Ausgelöst The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007 | Pubmed ID: 17267570 RGS Expression Rate-limits Recovery of Rod Photoresponses Neuron. Aug, 2006 | Pubmed ID: 16908407 Phototransduction in a Transgenic Mouse Model of Nougaret Night Blindness The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16793893 GAP-independent Termination of Photoreceptor Light Response by Excess Gamma Subunit of the CGMP-phosphodiesterase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16641226 Deactivation of Phosphorylated and Nonphosphorylated Rhodopsin by Arrestin Splice Variants The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16421323 Transducin Activation State Controls Its Light-dependent Translocation in Rod Photoreceptors The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16207703 D2 Dopamine Receptors Colocalize Regulator of G-protein Signaling 9-2 (RGS9-2) Via the RGS9 DEP Domain, and RGS9 Knock-out Mice Develop Dyskinesias Associated with Dopamine Pathways The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15728856 Rhodopsin-iCre Transgenic Mouse Line for Cre-mediated Rod-specific Gene Targeting Genesis (New York, N.Y. : 2000). Feb, 2005 | Pubmed ID: 15682388 Photoreceptor CGMP Phosphodiesterase Delta Subunit (PDEdelta) Functions As a Prenyl-binding Protein The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14561760 Die DEP-Domäne Bestimmt Subzellulären Targeting Des GTPase-aktivierendes Protein RGS9 in Vivo The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2003 | Pubmed ID: 14614075 Novel Form of Adaptation in Mouse Retinal Rods Speeds Recovery of Phototransduction The Journal of General Physiology. Dec, 2003 | Pubmed ID: 14610022 Prolonged Photoresponses and Defective Adaptation in Rods of Gbeta5-/- Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12904457 Retinal Remodeling Triggered by Photoreceptor Degenerations The Journal of Comparative Neurology. Sep, 2003 | Pubmed ID: 12866125 RGS9 Modulates Dopamine Signaling in the Basal Ganglia Neuron. Jun, 2003 | Pubmed ID: 12818179 Light-dependent Redistribution of Visual Arrestins and Transducin Subunits in Mice with Defective Phototransduction Molecular Vision. Jun, 2003 | Pubmed ID: 12802257 Instability of GGL Domain-containing RGS Proteins in Mice Lacking the G Protein Beta-subunit Gbeta5 Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12738888 Palmitoylation Regulates Regulators of G-protein Signaling (RGS) 16 Function. I. Mutation of Amino-terminal Cysteine Residues on RGS16 Prevents Its Targeting to Lipid Rafts and Palmitoylation of an Internal Cysteine Residue The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12642593 Recoverin and Rhodopsin Kinase Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 12596917 Evidence for Two Apoptotic Pathways in Light-induced Retinal Degeneration Nature Genetics. Oct, 2002 | Pubmed ID: 12219089 Patch-Clamp-Aufzeichnung von Starburst-Amakrinzellen in einer Wohnung Montage Herstellung von Deafferentated Maus Retina Hung-Ya Tu1, Chih-Chun Hsu1,2, Yu-Jiun Chen1, Ching-Kang Chen1,2,3 1Department of Ophthalmology, Baylor College of Medicine, 2Department of Neuroscience, Baylor College of Medicine, 3Department of Biochemistry and Molecular Biology, Baylor College of Medicine JoVE 54608 Neuroscience
Patch-Clamp-Aufzeichnung von Starburst-Amakrinzellen in einer Wohnung Montage Herstellung von Deafferentated Maus Retina Hung-Ya Tu1, Chih-Chun Hsu1,2, Yu-Jiun Chen1, Ching-Kang Chen1,2,3 1Department of Ophthalmology, Baylor College of Medicine, 2Department of Neuroscience, Baylor College of Medicine, 3Department of Biochemistry and Molecular Biology, Baylor College of Medicine JoVE 54608 Neuroscience