Christian Kühn Department of Cardiothoracic, Transplantation, and Vascular Surgery Hannover Medical School Biography Publications Institution JoVE Articles Christian Kühn has not added a biography. If you are Christian Kühn and would like to personalize this page please email our Author Liaison for assistance. Publications MicroRNA MiR-301a is a Novel Cardiac Regulator of Cofilin-2 PloS One. 2017 | Pubmed ID: 28886070 Technique and Outcomes of Less Invasive Lung Retransplantation Transplantation. Aug, 2017 | Pubmed ID: 28787308 The Cardiac Z-Disc Protein CEFIP Regulates Cardiomyocyte Hypertrophy By Modulating Calcineurin Signaling The Journal of Biological Chemistry. Jul, 2017 | Pubmed ID: 28717008 Repeated Human Leukocyte Antigen Mismatches in Lung Re-transplantation Transplant Immunology. Feb, 2017 | Pubmed ID: 27923603 Simultaneous Dual-isotope Solid-state Detector SPECT for Improved Tracking of White Blood Cells in Suspected Endocarditis European Heart Journal. Feb, 2017 | Pubmed ID: 27469371 Right-Sided Heart Failure and Extracorporeal Life Support in Patients Undergoing Pericardiectomy for Constrictive Pericarditis: A Risk Factor Analysis for Adverse Outcome The Thoracic and Cardiovascular Surgeon. Nov, 2016 | Pubmed ID: 27855469 First Successful Surgical Reconstruction of Bilateral Transected Main Bronchi With Extracorporeal Membrane Oxygenation Support The Annals of Thoracic Surgery. Aug, 2016 | Pubmed ID: 27449449 Deceleration Capacity: A Novel Predictor for Total Mortality in Patients with Non-ischemic Dilated Cardiomyopathy International Journal of Cardiology. Oct, 2016 | Pubmed ID: 27404693 Dyrk1a Regulates the Cardiomyocyte Cell Cycle Via D-cyclin-dependent Rb/E2f-signalling Cardiovascular Research. 06, 2016 | Pubmed ID: 27056896 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Myozap Deficiency Promotes Adverse Cardiac Remodeling Via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26719331 IgM-Enriched Human Intravenous Immunoglobulin-Based Treatment of Patients With Early Donor Specific Anti-HLA Antibodies After Lung Transplantation Transplantation. Dec, 2016 | Pubmed ID: 26714123 Cannulation Strategies for Percutaneous Extracorporeal Membrane Oxygenation in Adults Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Apr, 2016 | Pubmed ID: 26608160 Longtime Undetected Microcystic Adnexal Carcinoma of the Scalp: Considerations and Implications Oral and Maxillofacial Surgery. Jun, 2016 | Pubmed ID: 26556781 Single- and Multiple-dose Pharmacokinetics of Ethambutol and Rifampicin in a Tuberculosis Patient with Acute Respiratory Distress Syndrome Undergoing Extended Daily Dialysis and ECMO Treatment International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Jan, 2016 | Pubmed ID: 26518065 Postinfarction Posterior Ventricular Septal Rupture Mimicking a Biventricular Free Wall Rupture with Extracardiac Left-to-right Shunt International Journal of Cardiology. Heart & Vasculature. Dec, 2015 | Pubmed ID: 28785703 Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy Cell Metabolism. Dec, 2015 | Pubmed ID: 26437603 Survival and Spirometry Outcomes After Lung Transplantation from Donors Aged 70 Years and Older The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Oct, 2015 | Pubmed ID: 26186805 Orbital Lobe Resection Provides a Definite Diagnosis of Lacrimal Gland Lesions: a Report of Three Cases Oral and Maxillofacial Surgery. Dec, 2015 | Pubmed ID: 26099348 Heat-shock-protein 90 Protects from Downregulation of HIF-1α in Calcineurin-induced Myocardial Hypertrophy Journal of Molecular and Cellular Cardiology. Aug, 2015 | Pubmed ID: 26031702 Heart Against Veno-arterial ECMO: Competition Visualized International Journal of Cardiology. 2015 | Pubmed ID: 25828345 Cardiac Awake Extracorporeal Life Support-bridge to Decision? Artificial Organs. May, 2015 | Pubmed ID: 25597647 Preemptive Treatment with Therapeutic Plasma Exchange and Rituximab for Early Donor-specific Antibodies After Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2015 | Pubmed ID: 25447575 Lung Transplantation for Severe Pulmonary Hypertension--awake Extracorporeal Membrane Oxygenation for Postoperative Left Ventricular Remodelling Transplantation. Feb, 2015 | Pubmed ID: 25119128 Extracorporeal Membrane Oxygenation Watershed Circulation. Sep, 2014 | Pubmed ID: 25210098 Early Donor-specific Antibodies in Lung Transplantation: Risk Factors and Impact on Survival The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Dec, 2014 | Pubmed ID: 25070908 Mice with Cardiac-restricted Overexpression of Myozap Are Sensitized to Biomechanical Stress and Develop a Protein-aggregate-associated Cardiomyopathy Journal of Molecular and Cellular Cardiology. Jul, 2014 | Pubmed ID: 24698889 C1-esterase-inhibitor for Primary Graft Dysfunction in Lung Transplantation Transplantation. Jun, 2014 | Pubmed ID: 24573112 Monitoring of Patients Supported by Extracorporeal Membrane Oxygenation for Systemic Infections by Broad-range RRNA Gene PCR Amplification and Sequence Analysis Journal of Clinical Microbiology. Jan, 2014 | Pubmed ID: 24153127 Fasting Therapy - an Expert Panel Update of the 2002 Consensus Guidelines Forschende Komplementarmedizin (2006). 2013 | Pubmed ID: 24434758 Dysbindin is a Potent Inducer of RhoA-SRF-mediated Cardiomyocyte Hypertrophy The Journal of Cell Biology. Nov, 2013 | Pubmed ID: 24385487 Extended Criteria Donor Lungs and Clinical Outcome: Results of an Alternative Allocation Algorithm The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2013 | Pubmed ID: 23953918 Extracorporeal Membrane Oxygenation Instead of Invasive Mechanical Ventilation in Patients with Acute Respiratory Distress Syndrome Intensive Care Medicine. Nov, 2013 | Pubmed ID: 23921981 The Oral Cavity is Not a Primary Source for Implantable Pacemaker or Cardioverter Defibrillator Infections Journal of Cardiothoracic Surgery. Apr, 2013 | Pubmed ID: 23575037 Renal Function and Survival in 200 Patients Undergoing ECMO Therapy Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jan, 2013 | Pubmed ID: 23136216 Normothermic Perfusion of Donor Lungs for Preservation and Assessment with the Organ Care System Lung Before Bilateral Transplantation: a Pilot Study of 12 Patients Lancet (London, England). Nov, 2012 | Pubmed ID: 23063317 F-box and Leucine-rich Repeat Protein 22 is a Cardiac-enriched F-box Protein That Regulates Sarcomeric Protein Turnover and is Essential for Maintenance of Contractile Function in Vivo Circulation Research. Dec, 2012 | Pubmed ID: 22972877 Extracorporeal Membrane Oxygenation in a Nonintubated Patient with Acute Respiratory Distress Syndrome The European Respiratory Journal. Nov, 2012 | Pubmed ID: 22878882 Erythropoietin Enhances the Regeneration of Traumatized Tissue After Combined Muscle-nerve Injury The Journal of Trauma and Acute Care Surgery. Jun, 2012 | Pubmed ID: 22695424 Cardiac Remodeling is Not Modulated by Overexpression of Muscle LIM Protein (MLP) Basic Research in Cardiology. 2012 | Pubmed ID: 22421737 MicroRNA-20a Inhibits Stress-induced Cardiomyocyte Apoptosis Involving Its Novel Target Egln3/PHD3 Journal of Molecular and Cellular Cardiology. Mar, 2012 | Pubmed ID: 22182733 Lung Function Early After Lung Transplantation is Correlated with the Frequency of Regulatory T Cells Surgery Today. Feb, 2012 | Pubmed ID: 22173646 Atropisomerism of a Monosubstituted Perfluoro[2.2]paracyclophane. A Combined Synthetic, Kinetic, Spectroscopic and Computational Study Organic & Biomolecular Chemistry. Jan, 2012 | Pubmed ID: 22130578 Spirometric Obstructive Lung Function Pattern Early After Lung Transplantation Transplantation. Jan, 2012 | Pubmed ID: 22129764 The Plaque Protein Myozap Identified As a Novel Major Component of Adhering Junctions in Endothelia of the Blood and the Lymph Vascular Systems Journal of Cellular and Molecular Medicine. Aug, 2012 | Pubmed ID: 21992629 Evaluation of Commercial Universal RRNA Gene PCR Plus Sequencing Tests for Identification of Bacteria and Fungi Associated with Infectious Endocarditis Journal of Clinical Microbiology. Aug, 2011 | Pubmed ID: 21715592 脂肪組織由来の可溶性fms様チロシンキナーゼ1が肥満関連の内因性パラクリンAdipokineです。 Hypertension. Jul, 2011 | Pubmed ID: 21555675 Effect of Acute Kidney Injury Requiring Extended Dialysis on 28 Day and 1 Year Survival of Patients Undergoing Interventional Lung Assist Membrane Ventilator Treatment BMC Nephrology. Apr, 2011 | Pubmed ID: 21489261 Virus-associated Hemophagocytic Syndrome As a Major Contributor to Death in Patients with 2009 Influenza A (H1N1) Infection Critical Care (London, England). 2011 | Pubmed ID: 21366922 Affixin (β-parvin) Promotes Cardioprotective Signaling Via STAT3 Activation Journal of Molecular and Cellular Cardiology. May, 2011 | Pubmed ID: 21295579 Myomasp/LRRC39、心と筋特異蛋白質、サルコメア M バンドの新規コンポーネントです、ストレッチ センシングに関与しています。 Circulation Research. Nov, 2010 | Pubmed ID: 20847312 Treatment of Patients with Recurrent or Persistent Infection of Cardiac Implantable Electronic Devices Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Sep, 2010 | Pubmed ID: 20621894 Lmcd1/Dyxin, a Novel Z-disc Associated LIM Protein, Mediates Cardiac Hypertrophy in Vitro and in Vivo Journal of Molecular and Cellular Cardiology. Oct, 2010 | Pubmed ID: 20600098 Decrease of Deep Sternal Surgical Site Infection Rates After Cardiac Surgery by a Comprehensive Infection Control Program Interactive Cardiovascular and Thoracic Surgery. Aug, 2009 | Pubmed ID: 19416962 DYRK1A is a Novel Negative Regulator of Cardiomyocyte Hypertrophy The Journal of Biological Chemistry. Jun, 2009 | Pubmed ID: 19372220 Calsarcin-2 Deficiency Increases Exercise Capacity in Mice Through Calcineurin/NFAT Activation The Journal of Clinical Investigation. Nov, 2008 | Pubmed ID: 18846255 High Prevalence of Asymptomatic Bacterial Colonization of Rhythm Management Devices Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Sep, 2008 | Pubmed ID: 18658253 Gene Expression Pattern in Biomechanically Stretched Cardiomyocytes: Evidence for a Stretch-specific Gene Program Hypertension (Dallas, Tex. : 1979). Feb, 2008 | Pubmed ID: 18158353 Role of the Sarcomeric Z-disc in the Pathogenesis of Cardiomyopathy Future Cardiology. Nov, 2007 | Pubmed ID: 19804282 Calsarcin-1 Protects Against Angiotensin-II Induced Cardiac Hypertrophy Circulation. Nov, 2007 | Pubmed ID: 18025526 The Soluble Transferrin Receptor Reflects Tumor Load in Chronic Lymphocytic Leukemia Clinical Chemistry and Laboratory Medicine. 2007 | Pubmed ID: 17727315 Reliable Identification of Small Cell Lung Cancer in Cytological Specimens by Immunocytology Onkologie. Jun, 2007 | Pubmed ID: 17551254 The Soluble Transferrin Receptor in Dysplastic Erythropoiesis in Myelodysplastic Syndrome European Journal of Haematology. Jul, 2007 | Pubmed ID: 17532764 Effect of Immunoadsorption on Refractory Idiopathic Focal and Segmental Glomerulosclerosis Journal of Clinical Apheresis. Dec, 2006 | Pubmed ID: 17120233 Extravascular Lung Water Index: a New Method to Determine Dry Weight in Chronic Hemodialysis Patients Hemodialysis International. International Symposium on Home Hemodialysis. Jan, 2006 | Pubmed ID: 16441830 The Sarcomeric Z-disc: a Nodal Point in Signalling and Disease Journal of Molecular Medicine (Berlin, Germany). Jun, 2006 | Pubmed ID: 16416311 Surgical Treatment of an Aneurysm Involving Ascending Aorta, Aortic Arch, and a Rupture of a Descending Aortic Aneurysm 26 Years Following Acute Type A Aortic Dissection The Journal of Thoracic and Cardiovascular Surgery. Jan, 2006 | Pubmed ID: 16399322 Adhesive Functions of Both Chains of VLA-integrins Are Not Fully Conserved Across the Human-porcine Species Barrier: Implications for Xenotransplantation Xenotransplantation. Nov, 2005 | Pubmed ID: 16202071 Soluble Transferrin Receptor and Zinc Protoporphyrin--competitors or Efficient Partners? European Journal of Haematology. Oct, 2005 | Pubmed ID: 16146537 One-stage Treatment of Aortic Coarctation Associated with Coronary Heart Disease, Ascending Aortic Aneurysm, and Aortic Valve Stenosis with an Extra-anatomic Ascending-descending Aortic Bypass The Journal of Thoracic and Cardiovascular Surgery. Aug, 2005 | Pubmed ID: 16077440 Mice Lacking Calsarcin-1 Are Sensitized to Calcineurin Signaling and Show Accelerated Cardiomyopathy in Response to Pathological Biomechanical Stress Nature Medicine. Dec, 2004 | Pubmed ID: 15543153 A Frame Shifted Disulfide Bridged Analogue of Angiotensin II Bioorganic & Medicinal Chemistry. Mar, 2003 | Pubmed ID: 12614883 マウス モデルにおける心肺バイパス: 新しいアプローチ Nodir Madrahimov1, Ruslan Natanov1, Erin C. Boyle1, Tobias Goecke1, Ann-Kathrin Knöfel1, Valentyna Irkha1, Anna Solovieva2, Klaus Höffler1, Ulrich Maus3, Christian Kühn1, Issam Ismail1, Gregor Warnecke1, Malakh-Lal Shrestha1, Serghei Cebotari*1, Axel Haverich*1 1Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, 2Department of Hematology, Oncology, Immunology, Rheumatology, and Pulmonology, University Hospital Tuebingen, 3Department of Pneumology, Hannover Medical School JoVE 56017 Medicine
マウス モデルにおける心肺バイパス: 新しいアプローチ Nodir Madrahimov1, Ruslan Natanov1, Erin C. Boyle1, Tobias Goecke1, Ann-Kathrin Knöfel1, Valentyna Irkha1, Anna Solovieva2, Klaus Höffler1, Ulrich Maus3, Christian Kühn1, Issam Ismail1, Gregor Warnecke1, Malakh-Lal Shrestha1, Serghei Cebotari*1, Axel Haverich*1 1Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, 2Department of Hematology, Oncology, Immunology, Rheumatology, and Pulmonology, University Hospital Tuebingen, 3Department of Pneumology, Hannover Medical School JoVE 56017 Medicine