Chung-Yi Wu Genomics Research Center Academia Sinica Biography Publications Institution JoVE Articles Chung-Yi Wu has not added a biography. If you are Chung-Yi Wu and would like to personalize this page please email our Author Liaison for assistance. Publications Functional Roles of ST8SIA3-mediated Sialylation of Striatal Dopamine D and Adenosine A Receptors Translational Psychiatry. Aug, 2019 | Pubmed ID: 31455764 Synthesis of Sialidase-Resistant Oligosaccharide and Antibody Glycoform Containing α2,6-Linked 3F-Neu5Ac Journal of the American Chemical Society. Apr, 2019 | Pubmed ID: 30969765 The Uremic Toxin P-cresyl Sulfate Induces Proliferation and Migration of Clear Cell Renal Cell Carcinoma Via MicroRNA-21/ HIF-1α Axis Signals Scientific Reports. Mar, 2019 | Pubmed ID: 30824757 Signaling Pathway of Globo-series Glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. 02, 2019 | Pubmed ID: 30808745 Hierarchical and Programmable One-pot Synthesis of Oligosaccharides Nature Communications. 12, 2018 | Pubmed ID: 30523255 Pseudaminic Acid on Exopolysaccharide of Acinetobacter Baumannii Plays a Critical Role in Phage-Assisted Preparation of Glycoconjugate Vaccine with High Antigenicity Journal of the American Chemical Society. 07, 2018 | Pubmed ID: 29965749 -GlcNAcylation Regulates the Stability and Enzymatic Activity of the Histone Methyltransferase EZH2 Proceedings of the National Academy of Sciences of the United States of America. 07, 2018 | Pubmed ID: 29941599 Unprecedented Role of Hybrid N-Glycans As Ligands for HIV-1 Broadly Neutralizing Antibodies Journal of the American Chemical Society. 04, 2018 | Pubmed ID: 29578688 A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope Immunity. 03, 2018 | Pubmed ID: 29548671 Defining the Sizes of Airborne Particles That Mediate Influenza Transmission in Ferrets Proceedings of the National Academy of Sciences of the United States of America. 03, 2018 | Pubmed ID: 29463703 Glycoengineering of Antibody (Herceptin) Through Yeast Expression and in Vitro Enzymatic Glycosylation Proceedings of the National Academy of Sciences of the United States of America. Jan, 2018 | Pubmed ID: 29311294 Dual CLAVATA3 Peptides in Arabidopsis Shoot Stem Cell Signaling Journal of Plant Biology = Singmul Hakhoe Chi. Oct, 2017 | Pubmed ID: 30310351 Glycans Function As Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development Immunity. Sep, 2017 | Pubmed ID: 28916265 Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chemical Biology. May, 2017 | Pubmed ID: 28318221 Structural Basis for Fragmenting the Exopolysaccharide of Acinetobacter Baumannii by Bacteriophage ΦAB6 Tailspike Protein Scientific Reports. Feb, 2017 | Pubmed ID: 28209973 An Effective Bacterial Fucosidase for Glycoprotein Remodeling ACS Chemical Biology. 01, 2017 | Pubmed ID: 28103685 Influenza A Surface Glycosylation and Vaccine Design Proceedings of the National Academy of Sciences of the United States of America. Jan, 2017 | Pubmed ID: 28028222 Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays ACS Omega. Nov, 2016 | Pubmed ID: 30023491 Functionalized HgTe Nanoparticles Promote Laser-induced Solid Phase Ionization/dissociation for Comprehensive Glycan Sequencing The Analyst. Oct, 2016 | Pubmed ID: 27722232 A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans Immunity. 07, 2016 | Pubmed ID: 27438765 Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch Immunity. 05, 2016 | Pubmed ID: 27192579 Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Cell. May, 2016 | Pubmed ID: 27114034 A Multivalent Marine Lectin from Crenomytilus Grayanus Possesses Anti-cancer Activity Through Recognizing Globotriose Gb3 Journal of the American Chemical Society. Apr, 2016 | Pubmed ID: 27010847 Modular Synthesis of N-glycans and Arrays for the Hetero-ligand Binding Analysis of HIV Antibodies Nature Chemistry. Apr, 2016 | Pubmed ID: 27001729 Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design Immunity. Nov, 2015 | Pubmed ID: 26588781 A Common Glycan Structure on Immunoglobulin G for Enhancement of Effector Functions Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26253764 Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity The Journal of Biological Chemistry. Aug, 2015 | Pubmed ID: 26170455 Sialoside Arrays: New Synthetic Strategies and Applications Topics in Current Chemistry. Month, 2015 | Pubmed ID: 25707616 Immunogenicity Study of Globo H Analogues with Modification at the Reducing or Nonreducing End of the Tumor Antigen Journal of the American Chemical Society. Dec, 2014 | Pubmed ID: 25371992 Sequence-constructive SELEX: a New Strategy for Screening DNA Aptamer Binding to Globo H Biochemical and Biophysical Research Communications. Sep, 2014 | Pubmed ID: 25159850 Development of a Highly Sensitive Glycan Microarray for Quantifying AFP-L3 for Early Prediction of Hepatitis B Virus-related Hepatocellular Carcinoma PloS One. Month, 2014 | Pubmed ID: 24927126 Broadly Neutralizing HIV Antibodies Define a Glycan-dependent Epitope on the Prefusion Conformation of Gp41 on Cleaved Envelope Trimers Immunity. May, 2014 | Pubmed ID: 24768347 Characterization of the Sialic Acid Binding Activity of Influenza A Viruses Using Soluble Variants of the H7 and H9 Hemagglutinins PloS One. Month, 2014 | Pubmed ID: 24586849 Stage-specific Embryonic Antigen-4 As a Potential Therapeutic Target in Glioblastoma Multiforme and Other Cancers Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24550271 Chemical Constituents of Plectranthus Amboinicus and the Synthetic Analogs Possessing Anti-inflammatory Activity Bioorganic & Medicinal Chemistry. Mar, 2014 | Pubmed ID: 24491635 Vaccination of Monoglycosylated Hemagglutinin Induces Cross-strain Protection Against Influenza Virus Infections Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24469815 Downregulation of MicroRNA-15b by Hepatitis B Virus X Enhances Hepatocellular Carcinoma Proliferation Via Fucosyltransferase 2-induced Globo H Expression International Journal of Cancer. Apr, 2014 | Pubmed ID: 24122375 Global Assessment of Antrodia Cinnamomea-induced MicroRNA Alterations in Hepatocarcinoma Cells PloS One. Month, 2013 | Pubmed ID: 24358224 Effective Sugar Nucleotide Regeneration for the Large-scale Enzymatic Synthesis of Globo H and SSEA4 Journal of the American Chemical Society. Oct, 2013 | Pubmed ID: 24044869 Efficient Convergent Synthesis of Bi-, Tri-, and Tetra-antennary Complex Type N-glycans and Their HIV-1 Antigenicity Journal of the American Chemical Society. Oct, 2013 | Pubmed ID: 24032650 Immunization of Fucose-containing Polysaccharides from Reishi Mushroom Induces Antibodies to Tumor-associated Globo H-series Epitopes Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23908400 Synthesis of Neisseria Meningitidis Serogroup W135 Capsular Oligosaccharides for Immunogenicity Comparison and Vaccine Development Angewandte Chemie (International Ed. in English). Aug, 2013 | Pubmed ID: 23843313 Synthesis and Vaccine Evaluation of the Tumor-associated Carbohydrate Antigen RM2 from Prostate Cancer Journal of the American Chemical Society. Jul, 2013 | Pubmed ID: 23819648 Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-mannose, High-mannose, or Complex Type N-glycans PloS One. Month, 2013 | Pubmed ID: 23799128 CLEC4F is an Inducible C-type Lectin in F4/80-positive Cells and is Involved in Alpha-galactosylceramide Presentation in Liver PloS One. Month, 2013 | Pubmed ID: 23762286 The Immunologically Active Oligosaccharides Isolated from Wheatgrass Modulate Monocytes Via Toll-like Receptor-2 Signaling The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23629653 Carbohydrate-based Vaccines with a Glycolipid Adjuvant for Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23355685 Chemical Probes for Drug-resistance Assessment by Binding Competition (RABC): Oseltamivir Susceptibility Evaluation Angewandte Chemie (International Ed. in English). Jan, 2013 | Pubmed ID: 23150231 Cancer-associated Carbohydrate Antigens As Potential Biomarkers for Hepatocellular Carcinoma PloS One. Month, 2012 | Pubmed ID: 22808038 Infection of Differentiated Porcine Airway Epithelial Cells by Influenza Virus: Differential Susceptibility to Infection by Porcine and Avian Viruses PloS One. Month, 2011 | Pubmed ID: 22174804 Toward Automated Oligosaccharide Synthesis Angewandte Chemie (International Ed. in English). Dec, 2011 | Pubmed ID: 22127846 Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: from Monomers to Dodecamers Angewandte Chemie (International Ed. in English). Sep, 2011 | Pubmed ID: 21948436 Hemagglutinin-neuraminidase Balance Confers Respiratory-droplet Transmissibility of the Pandemic H1N1 Influenza Virus in Ferrets Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21825167 The SUMOylation of Matrix Protein M1 Modulates the Assembly and Morphogenesis of Influenza A Virus Journal of Virology. Jul, 2011 | Pubmed ID: 21507966 Chemistry and Glycobiology Chemical Communications (Cambridge, England). Jun, 2011 | Pubmed ID: 21503322 Broadly Neutralizing DNA Vaccine with Specific Mutation Alters the Antigenicity and Sugar-binding Activities of Influenza Hemagglutinin Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21321237 Effects of Neighboring Glycans on Antibody-carbohydrate Interaction Angewandte Chemie (International Ed. in English). Feb, 2011 | Pubmed ID: 21308915 Programmable One-pot Glycosylation Topics in Current Chemistry. Month, 2011 | Pubmed ID: 21290217 Carbohydrate-based Vaccines: Challenges and Opportunities Expert Review of Vaccines. Nov, 2010 | Pubmed ID: 21087106 High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20974907 Ubiquitination and Deubiquitination of NP Protein Regulates Influenza A Virus RNA Replication The EMBO Journal. Nov, 2010 | Pubmed ID: 20924359 Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays Journal of the American Chemical Society. Oct, 2010 | Pubmed ID: 20882975 Glycan Array on Aluminum Oxide-coated Glass Slides Through Phosphonate Chemistry Journal of the American Chemical Society. Sep, 2010 | Pubmed ID: 20822102 Ultrasound Ionization of Biomolecules Rapid Communications in Mass Spectrometry : RCM. Sep, 2010 | Pubmed ID: 20740532 Highly Alpha-selective Sialyl Phosphate Donors for Efficient Preparation of Natural Sialosides Chemistry (Weinheim an Der Bergstrasse, Germany). Feb, 2010 | Pubmed ID: 20066711 Glycan Array: a Powerful Tool for Glycomics Studies Expert Review of Proteomics. Dec, 2009 | Pubmed ID: 19929609 Glycans on Influenza Hemagglutinin Affect Receptor Binding and Immune Response Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009 | Pubmed ID: 19822741 Iron Oxide/gold Core/shell Nanoparticles for Ultrasensitive Detection of Carbohydrate-protein Interactions Analytical Chemistry. Sep, 2009 | Pubmed ID: 19689135 New Development of Glycan Arrays Organic & Biomolecular Chemistry. Jun, 2009 | Pubmed ID: 19462030 HA-pseudotyped Retroviral Vectors for Influenza Antagonist Screening Journal of Biomolecular Screening. Mar, 2009 | Pubmed ID: 19211776 Glycan Microarray of Globo H and Related Structures for Quantitative Analysis of Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18689688 Glycan Arrays on Aluminum-coated Glass Slides Chemistry, an Asian Journal. Sep, 2008 | Pubmed ID: 18683161 Discovery of Different Types of Inhibition Between the Human and Thermotoga Maritima Alpha-fucosidases by Fuconojirimycin-based Derivatives Biochemistry. May, 2006 | Pubmed ID: 16669613 Stable Benzotriazole Esters As Mechanism-based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease Chemistry & Biology. Mar, 2006 | Pubmed ID: 16638531 Discovery of Picomolar Slow Tight-binding Inhibitors of Alpha-fucosidase Chemistry & Biology. Sep, 2004 | Pubmed ID: 15380190 Small Molecules Targeting Severe Acute Respiratory Syndrome Human Coronavirus Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15226499 Rapid Diversity-oriented Synthesis in Microtiter Plates for in Situ Screening: Discovery of Potent and Selective Alpha-fucosidase Inhibitors Angewandte Chemie (International Ed. in English). Oct, 2003 | Pubmed ID: 14533157 Stereoselective Glycosylation of Exo-glycals Accelerated by Ferrier-type Rearrangement Organic Letters. Apr, 2003 | Pubmed ID: 12659580 Synthèse hiérarchique et programmable d'oligosaccharide d'un pot Cheng-Wei Cheng1, Yixuan Zhou1, Wen-Harn Pan2, Supriya Dey3, Chung-Yi Wu1, Wen-Lian Hsu4, Chi-Huey Wong1,3 1Genomics Research Center, Academia Sinica, 2Institute of Biomedical Sciences, Academia Sinica, 3Department of Chemistry, Scripps Research Institute, 4Institute of Information Science, Academia Sinica JoVE 59987 Chemistry Synthèse de chimio-enzymatique des N- glycans pour le développement de la baie et anticorps anti-VIH de profilage Sachin S. Shivatare1, Vidya S. Shivatare1, Chung-Yi Wu1, Chi-Huey Wong1 1Genomics Research Center, Academia Sinica JoVE 55855 Chemistry
Synthèse hiérarchique et programmable d'oligosaccharide d'un pot Cheng-Wei Cheng1, Yixuan Zhou1, Wen-Harn Pan2, Supriya Dey3, Chung-Yi Wu1, Wen-Lian Hsu4, Chi-Huey Wong1,3 1Genomics Research Center, Academia Sinica, 2Institute of Biomedical Sciences, Academia Sinica, 3Department of Chemistry, Scripps Research Institute, 4Institute of Information Science, Academia Sinica JoVE 59987 Chemistry
Synthèse de chimio-enzymatique des N- glycans pour le développement de la baie et anticorps anti-VIH de profilage Sachin S. Shivatare1, Vidya S. Shivatare1, Chung-Yi Wu1, Chi-Huey Wong1 1Genomics Research Center, Academia Sinica JoVE 55855 Chemistry