Coleen McNamara Cardiovascular Research Center University of Virginia Biography Publications Institution JoVE Articles Coleen McNamara has not added a biography. If you are Coleen McNamara and would like to personalize this page please email our Author Liaison for assistance. Publications PPARγ and PPARα Synergize to Induce Robust Browning of White Fat In vivo Molecular Metabolism. Jun, 2020 | Pubmed ID: 32248079 B Lymphocytes and Adipose Tissue Inflammation Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2020 | Pubmed ID: 32131612 Liposomal Delivery of PPARα/γ Dual Agonist Tesaglitazar in a Model of Obesity Enriches Macrophage Targeting and Limits Liver and Kidney Drug Effects Theranostics. 2020 | Pubmed ID: 31903139 2019 Russell Ross Memorial Lecture in Vascular Biology: B Lymphocyte-Mediated Protective Immunity in Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 02, 2020 | Pubmed ID: 31852222 Novel Autoimmune IgM Antibody Attenuates Atherosclerosis in IgM Deficient Low-Fat Diet-Fed, but Not Western Diet-Fed Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 01, 2020 | Pubmed ID: 31645128 Cardiac Resynchronization Therapy Reduces Expression of Inflammation-promoting Genes Related to Interleukin-1β in Heart Failure Cardiovascular Research. Jun, 2020 | Pubmed ID: 31612215 Importance of Thorough Tissue and Cellular Level Characterization of Targeted Drugs in the Evaluation of Pharmacodynamic Effects PloS One. 2019 | Pubmed ID: 31725756 Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis Circulation Research. Oct, 2019 | Pubmed ID: 31549940 Cell- and Sex-Specific Role of FcγR (Fcγ Receptor) IIb in Experimental Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2019 | Pubmed ID: 31242029 C-Myb Exacerbates Atherosclerosis Through Regulation of Protective IgM-Producing Antibody-Secreting Cells Cell Reports. 05, 2019 | Pubmed ID: 31116977 IgE, α-Gal and Atherosclerosis Aging. 04, 2019 | Pubmed ID: 30958794 Human Monocyte Heterogeneity As Revealed by High-Dimensional Mass Cytometry Arteriosclerosis, Thrombosis, and Vascular Biology. 01, 2019 | Pubmed ID: 30580568 A Monoclonal Antibody to Assess Oxidized Cholesteryl Esters Associated with ApoAI and ApoB-100 Lipoproteins in Human Plasma Journal of Lipid Research. 02, 2019 | Pubmed ID: 30563909 IgE to the Mammalian Oligosaccharide Galactose-α-1,3-Galactose Is Associated With Increased Atheroma Volume and Plaques With Unstable Characteristics-Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2018 | Pubmed ID: 29903734 Apolipoprotein AI Prevents Regulatory to Follicular Helper T Cell Switching During Atherosclerosis Nature Communications. 03, 2018 | Pubmed ID: 29545616 Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease Journal of Cardiovascular Translational Research. 06, 2018 | Pubmed ID: 29344841 Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells Frontiers in Physiology. 2017 | Pubmed ID: 28970806 Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 11, 2017 | Pubmed ID: 28935758 Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry Arteriosclerosis, Thrombosis, and Vascular Biology. 08, 2017 | Pubmed ID: 28596372 B Cells and Atherosclerosis American Journal of Physiology. Heart and Circulatory Physiology. May, 2017 | Pubmed ID: 28314764 Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology Antioxidants & Redox Signaling. 05, 2017 | Pubmed ID: 27841660 Corrigendum to "Measurement of Microparticle Tissue Factor Activity in Clinical Samples: A Summary of Two Tissue Factor-dependent FXa Generation Assays" [Thromb. Res. 139 (2016) 90-97] Thrombosis Research. 11, 2016 | Pubmed ID: 27676256 B-Cell Depletion Promotes Aortic Infiltration of Immunosuppressive Cells and Is Protective of Experimental Aortic Aneurysm Arteriosclerosis, Thrombosis, and Vascular Biology. 11, 2016 | Pubmed ID: 27634836 Loss of ABCG1 Influences Regulatory T Cell Differentiation and Atherosclerosis The Journal of Clinical Investigation. 09, 2016 | Pubmed ID: 27482882 Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 06, 2016 | Pubmed ID: 27102965 Measurement of Microparticle Tissue Factor Activity in Clinical Samples: A Summary of Two Tissue Factor-dependent FXa Generation Assays Thrombosis Research. 03, 2016 | Pubmed ID: 26916302 Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2016 | Pubmed ID: 26868208 Adipocyte Progenitor Cells Initiate Monocyte Chemoattractant Protein-1-mediated Macrophage Accumulation in Visceral Adipose Tissue Molecular Metabolism. Nov, 2015 | Pubmed ID: 26629403 Pannexin 1 is Required for Full Activation of Insulin-stimulated Glucose Uptake in Adipocytes Molecular Metabolism. Sep, 2015 | Pubmed ID: 26413467 B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis Circulation Research. Jul, 2015 | Pubmed ID: 26082558 B2 Cells Suppress Experimental Abdominal Aortic Aneurysms The American Journal of Pathology. Nov, 2014 | Pubmed ID: 25194661 Inhibitor of Differentiation 3, a Transcription Factor, Regulates Hyperlipidemia-associated Kidney Disease Nephron. Experimental Nephrology. 2014 | Pubmed ID: 24854879 A Functionally Significant Polymorphism in ID3 is Associated with Human Coronary Pathology PloS One. 2014 | Pubmed ID: 24603695 Understanding the Role of B Cells in Atherosclerosis: Potential Clinical Implications Expert Review of Clinical Immunology. Jan, 2014 | Pubmed ID: 24308836 Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages PloS One. 2013 | Pubmed ID: 24376657 Helix-loop-helix Factor Inhibitor of Differentiation 3 Regulates Interleukin-5 Expression and B-1a B Cell Proliferation Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2013 | Pubmed ID: 24115031 B Cell Subsets in Atherosclerosis Frontiers in Immunology. 2012 | Pubmed ID: 23248624 Loss of Id3 Increases VCAM-1 Expression, Macrophage Accumulation, and Atherogenesis in Ldlr-/- Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2012 | Pubmed ID: 23042815 Usefulness of Cardiovascular Magnetic Resonance Imaging of the Superficial Femoral Artery for Screening Patients with Diabetes Mellitus for Atherosclerosis The American Journal of Cardiology. Jul, 2012 | Pubmed ID: 22459304 Lymphocytes and the Adventitial Immune Response in Atherosclerosis Circulation Research. Mar, 2012 | Pubmed ID: 22427326 Inhibitor of Differentiation-3 Mediates High Fat Diet-induced Visceral Fat Expansion Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2012 | Pubmed ID: 22075252 De Células B Aórtica Homing Y Atheroprotection Depende Id3 Circulation Research. Jan, 2012 | Pubmed ID: 22034493 Deficiency of a Transcriptional Regulator, Inhibitor of Differentiation 3, Induces Glomerulonephritis in Apolipoprotein E-deficient Mice: a Model Linking Hyperlipidemia and Renal Disease The American Journal of Pathology. Aug, 2011 | Pubmed ID: 21801865 Increased 12/15-lipoxygenase Enhances Cell Growth, Fibronectin Deposition, and Neointimal Formation in Response to Carotid Injury Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2011 | Pubmed ID: 20947825 Id3 is a Novel Atheroprotective Factor Containing a Functionally Significant Single-nucleotide Polymorphism Associated with Intima-media Thickness in Humans Circulation Research. Apr, 2010 | Pubmed ID: 20185798 Association of Plasma Sphingomyelin Levels and Incident Coronary Heart Disease Events in an Adult Population: Multi-Ethnic Study of Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2010 | Pubmed ID: 20032291 Angiotensina II Induce Una Hiperplasia De La Región Específica De La Aorta Ascendente a Través De La Regulación Del Inhibidor De La Diferenciación 3 Circulation Research. Feb, 2010 | Pubmed ID: 20019328 The Helix-loop-helix Factors Id3 and E47 Are Novel Regulators of Adiponectin Circulation Research. Sep, 2008 | Pubmed ID: 18669923 Reduced Expression of ATP-binding Cassette Transporter G1 Increases Cholesterol Accumulation in Macrophages of Patients with Type 2 Diabetes Mellitus Circulation. May, 2008 | Pubmed ID: 18490524 Role of Smooth Muscle Cells in the Initiation and Early Progression of Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2008 | Pubmed ID: 18276911 Are Thiazolidinediones Good or Bad for the Heart? Current Diabetes Reports. Nov, 2006 | Pubmed ID: 17076999 Hyperlipemia and Oxidation of LDL Induce Vascular Smooth Muscle Cell Growth: an Effect Mediated by the HLH Factor Id3 Journal of Vascular Research. 2006 | Pubmed ID: 16340216 Phosphatidylinositol-3-kinase Signaling Mediates Vascular Smooth Muscle Cell Expression of Periostin in Vivo and in Vitro Atherosclerosis. Oct, 2006 | Pubmed ID: 16325820 The Effects of Leukocyte-type 12/15-lipoxygenase on Id3-mediated Vascular Smooth Muscle Cell Growth Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2005 | Pubmed ID: 16037566 Id Family of Transcription Factors and Vascular Lesion Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2004 | Pubmed ID: 15345510 Phosphorylation Regulates Id3 Function in Vascular Smooth Muscle Cells Circulation Research. Sep, 2004 | Pubmed ID: 15321928 Intron Retention Generates a Novel Id3 Isoform That Inhibits Vascular Lesion Formation The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15159391 Regulation of Vascular Smooth Muscle Cell Growth: Targeting the Final Common Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2003 | Pubmed ID: 14555641 Noggin Overexpression Inhibits Eyelid Opening by Altering Epidermal Apoptosis and Differentiation The EMBO Journal. Jun, 2003 | Pubmed ID: 12805214 Contribution of the Helix-loop-helix Factor Id2 to Regulation of Vascular Smooth Muscle Cell Proliferation The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11706002 Hepatoma-derived Growth Factor Stimulates Smooth Muscle Cell Growth and is Expressed in Vascular Development The Journal of Clinical Investigation. Mar, 2000 | Pubmed ID: 10712428 Sobreexpresión retroviral de CXCR4 en células murinas B-1a y transferencia adoptiva para la migración celular B-1a dirigida a la médula ósea y la producción de IgM Aditi Upadhye1, Melissa Marshall2, James C. Garmey2, Timothy P. Bender3, Coleen McNamara2 1Department of Microbiology, Immunology, Cancer Biology, University of Virginia, 2Cardiovascular Research Center, University of Virginia, 3Beirne B. Carter Center for Immunology Research, University of Virginia JoVE 61003 Immunology and Infection
Sobreexpresión retroviral de CXCR4 en células murinas B-1a y transferencia adoptiva para la migración celular B-1a dirigida a la médula ósea y la producción de IgM Aditi Upadhye1, Melissa Marshall2, James C. Garmey2, Timothy P. Bender3, Coleen McNamara2 1Department of Microbiology, Immunology, Cancer Biology, University of Virginia, 2Cardiovascular Research Center, University of Virginia, 3Beirne B. Carter Center for Immunology Research, University of Virginia JoVE 61003 Immunology and Infection
