Cornelis van Breemen

Publications

• Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras
  PloS One. 2015  |   Pubmed ID: 26516777
• Drop in Endo/sarcoplasmic Calcium Precedes the Unfolded Protein Response in Brefeldin A-treated Vascular Smooth Muscle Cells
  European Journal of Pharmacology. Oct, 2015  |   Pubmed ID: 26172080
• Cytoplasmic Nanojunctions Between Lysosomes and Sarcoplasmic Reticulum Are Required for Specific Calcium Signaling
  F1000Research. 2014  |   Pubmed ID: 25126414
• Quantification of Aortic and Cutaneous Elastin and Collagen Morphology in Marfan Syndrome by Multiphoton Microscopy
  Journal of Structural Biology. Sep, 2014  |   Pubmed ID: 25086405
• Calcium Regulation in Aortic Smooth Muscle Cells During the Initial Phase of Tunicamycin-induced Endo/sarcoplasmic Reticulum Stress
  European Journal of Pharmacology. Jul, 2014  |   Pubmed ID: 24769510
• Calcium Oscillations in Human Mesenteric Vascular Smooth Muscle
  Biochemical and Biophysical Research Communications. Feb, 2014  |   Pubmed ID: 24508261
• Waves of Calcium Depletion in the Sarcoplasmic Reticulum of Vascular Smooth Muscle Cells: an Inside View of Spatiotemporal Ca2+ Regulation
  PloS One. 2013  |   Pubmed ID: 23408969
• Pan-junctional Sarcoplasmic Reticulum in Vascular Smooth Muscle: Nanospace Ca2+ Transport for Site- and Function-specific Ca2+ Signalling
  The Journal of Physiology. Apr, 2013  |   Pubmed ID: 23339179
• The Role of Cytoplasmic Nanospaces in Smooth Muscle Cell Ca2+ Signalling
  Protoplasma. Feb, 2012  |   Pubmed ID: 22083879
• The Structure and Functioning of the Couplon in the Mammalian Cardiomyocyte
  Protoplasma. Feb, 2012  |   Pubmed ID: 22057630
• Exposure to Diesel Exhaust Up-regulates INOS Expression in ApoE Knockout Mice
  Toxicology and Applied Pharmacology. Sep, 2011  |   Pubmed ID: 21722660
• Changes in Atherosclerotic Plaques Induced by Inhalation of Diesel Exhaust
  Atherosclerosis. Jun, 2011  |   Pubmed ID: 21435644
• Diosgenin Modulates Vascular Smooth Muscle Cell Function by Regulating Cell Viability, Migration, and Calcium Homeostasis
  The Journal of Pharmacology and Experimental Therapeutics. Mar, 2011  |   Pubmed ID: 21177478
• Effectiveness of Combination of Losartan Potassium and Doxycycline Versus Single-drug Treatments in the Secondary Prevention of Thoracic Aortic Aneurysm in Marfan Syndrome
  The Journal of Thoracic and Cardiovascular Surgery. Aug, 2010  |   Pubmed ID: 20189193
• Integrin-linked Kinase Functions As a Downstream Signal of Platelet-derived Growth Factor to Regulate Actin Polymerization and Vascular Smooth Muscle Cell Migration
  BMC Cell Biology. 2010  |   Pubmed ID: 20178627
• A Comparative Study of Alpha-adrenergic Receptor Mediated Ca(2+) Signals and Contraction in Intact Human and Mouse Vascular Smooth Muscle
  European Journal of Pharmacology. Mar, 2010  |   Pubmed ID: 20004190
• Vasomotor Dysfunction in the Thoracic Aorta of Marfan Syndrome is Associated with Accumulation of Oxidative Stress
  Vascular Pharmacology. Jan-Feb, 2010  |   Pubmed ID: 19879959
• Long-term Effects of Losartan on Structure and Function of the Thoracic Aorta in a Mouse Model of Marfan Syndrome
  British Journal of Pharmacology. Nov, 2009  |   Pubmed ID: 19814725
• A Model for the Generation of Localized Transient [Na+] Elevations in Vascular Smooth Muscle
  Biochemical and Biophysical Research Communications. Nov, 2009  |   Pubmed ID: 19733153
• Diabetes Modulates Capacitative Calcium Entry and Expression of Transient Receptor Potential Canonical Channels in Human Saphenous Vein
  European Journal of Pharmacology. Jun, 2009  |   Pubmed ID: 19393642
• Mitochondrial Regulation of Sarcoplasmic Reticulum Ca2+ Content in Vascular Smooth Muscle Cells
  Circulation Research. Jan, 2009  |   Pubmed ID: 19023135
• Characteristics of Agonist-induced Ca2+ Responses in Diseased Human Valvular Myofibroblasts
  Proceedings of the Western Pharmacology Society. 2008  |   Pubmed ID: 19544665
• Ca2+ Signaling in Smooth Muscle: TRPC6, NCX and LNats in Nanodomains
  Channels (Austin, Tex.). Jan-Feb, 2008  |   Pubmed ID: 18690050
• P2Y2 Receptor-mediated Ca2+ Signaling and Spontaneous Ca2+ Releases in Human Valvular Myofibroblasts
  International Heart Journal. Mar, 2008  |   Pubmed ID: 18475022
• Long-term Doxycycline is More Effective Than Atenolol to Prevent Thoracic Aortic Aneurysm in Marfan Syndrome Through the Inhibition of Matrix Metalloproteinase-2 and -9
  Circulation Research. Apr, 2008  |   Pubmed ID: 18388324
• Mechanical and Pharmacological Approaches to Investigate the Pathogenesis of Marfan Syndrome in the Abdominal Aorta
  Journal of Vascular Research. 2008  |   Pubmed ID: 18212506
• Arterialization of a Vein Graft Promotes Cell Cycle Progression Through Akt and P38 Mitogen-activated Protein Kinase Pathways: Impact of the Preparation Procedure
  The Canadian Journal of Cardiology. Dec, 2007  |   Pubmed ID: 18060101
• Transient Receptor Potential Channel 6-mediated, Localized Cytosolic [Na+] Transients Drive Na+/Ca2+ Exchanger-mediated Ca2+ Entry in Purinergically Stimulated Aorta Smooth Muscle Cells
  Circulation Research. Nov, 2007  |   Pubmed ID: 17872462
• Endothelin-1-mediated Wave-like [Ca2+]i Oscillations in Intact Rabbit Inferior Vena Cava
  Journal of Vascular Research. 2007  |   Pubmed ID: 17657165
• Loss of Elastic Fiber Integrity and Reduction of Vascular Smooth Muscle Contraction Resulting from the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in the Thoracic Aortic Aneurysm in Marfan Syndrome
  Circulation Research. Aug, 2007  |   Pubmed ID: 17641224
• Hyperglycemia and Hyperlipidemia Are Associated with Endothelial Dysfunction During the Development of Type 2 Diabetes
  Canadian Journal of Physiology and Pharmacology. May, 2007  |   Pubmed ID: 17632592
• ATP Promotes NCX-reversal in Aortic Smooth Muscle Cells by DAG-activated Na+ Entry
  Biochemical and Biophysical Research Communications. Jun, 2007  |   Pubmed ID: 17466270
• A Quantitative Model for Linking Na+/Ca2+ Exchanger to SERCA During Refilling of the Sarcoplasmic Reticulum to Sustain [Ca2+] Oscillations in Vascular Smooth Muscle
  Cell Calcium. Dec, 2007  |   Pubmed ID: 17418403
• Enhanced Cell Cycle Entry and Mitogen-activated Protein Kinase-signaling and Downregulation of Matrix Metalloproteinase-1 and -3 in Human Diabetic Arterial Vasculature
  Atherosclerosis. Nov, 2007  |   Pubmed ID: 17316652
• Acetylcholine-induced Asynchronous Calcium Waves in Intact Human Bronchial Muscle Bundle
  American Journal of Respiratory Cell and Molecular Biology. May, 2007  |   Pubmed ID: 17170384
• Na+ Entry Via TRPC6 Causes Ca2+ Entry Via NCX Reversal in ATP Stimulated Smooth Muscle Cells
  Biochemical and Biophysical Research Communications. Jan, 2007  |   Pubmed ID: 17112478
• Pharmacologic Relaxation of Vein Grafts is Beneficial Compared with Pressure Distention Caused by Upregulation of Endothelial Nitric Oxide Synthase and Nitric Oxide Production
  The Journal of Thoracic and Cardiovascular Surgery. Oct, 2006  |   Pubmed ID: 17000306
• Mitochondria Buffer NCX-mediated Ca2+-entry and Limit Its Diffusion into Vascular Smooth Muscle Cells
  Cell Calcium. Oct, 2006  |   Pubmed ID: 16806462
• Reduced Expression of Vascular Endothelial Growth Factor Paralleled with the Increased Angiostatin Expression Resulting from the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in Human Type 2 Diabetic Arterial Vasculature
  Circulation Research. Jul, 2006  |   Pubmed ID: 16778129
• Human Vascular Smooth Muscle Cells from Diabetic Patients Are Resistant to Induced Apoptosis Due to High Bcl-2 Expression
  Diabetes. May, 2006  |   Pubmed ID: 16644678
• TRP Proteins: a New Dimension in the Treatment of Occlusive Vascular Disease
  Circulation Research. Mar, 2006  |   Pubmed ID: 16514075
• Mechanism of ACh-induced Asynchronous Calcium Waves and Tonic Contraction in Porcine Tracheal Muscle Bundle
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2006  |   Pubmed ID: 16214818
• Asynchronous Calcium Waves in Smooth Muscle Cells
  Canadian Journal of Physiology and Pharmacology. Aug-Sep, 2005  |   Pubmed ID: 16333375
• Pressure Distention Compared with Pharmacologic Relaxation in Vein Grafting Upregulates Matrix Metalloproteinase-2 and -9
  Journal of Vascular Surgery. Oct, 2005  |   Pubmed ID: 16242564
• Compromised Arterial Function in Human Type 2 Diabetic Patients
  Diabetes. Aug, 2005  |   Pubmed ID: 16046309
• Rearrangement of the Close Contact Between the Mitochondria and the Sarcoplasmic Reticulum in Airway Smooth Muscle
  Cell Calcium. Apr, 2005  |   Pubmed ID: 15755494
• Calyculin-A Disrupts Subplasmalemmal Junction and Recurring Ca2+ Waves in Vascular Smooth Muscle
  Cell Calcium. Jan, 2005  |   Pubmed ID: 15541459
• Basal Calcium Entry in Vascular Smooth Muscle
  European Journal of Pharmacology. Nov, 2004  |   Pubmed ID: 15556133
• Vectorial Ca2+ Release Via Ryanodine Receptors Contributes to Ca2+ Extrusion from Freshly Isolated Rabbit Aortic Endothelial Cells
  Cell Calcium. Nov, 2004  |   Pubmed ID: 15451626
• Estrogen Modulation of Endothelium-derived Relaxing Factors by Human Endothelial Cells
  Biochemical and Biophysical Research Communications. Sep, 2004  |   Pubmed ID: 15325240
• Involvement of Inositol 1,4,5-trisphosphate in Nicotinic Calcium Responses in Dystrophic Myotubes Assessed by Near-plasma Membrane Calcium Measurement
  The Journal of Biological Chemistry. Nov, 2004  |   Pubmed ID: 15322099
• Vascular Smooth Muscle Mitochondria at the Cross Roads of Ca(2+) Regulation
  Cell Calcium. Jun, 2004  |   Pubmed ID: 15110141
• Novel Regulatory Mechanism of Cardiomyocyte Contractility Involving ICAM-1 and the Cytoskeleton
  American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2004  |   Pubmed ID: 15087287
• Differential Regulation of Calcium Homeostasis in Adenocarcinoma Cell Line A549 and Its Taxol-resistant Subclone
  British Journal of Pharmacology. May, 2004  |   Pubmed ID: 15066902
• Traction Injury During Minimally Invasive Harvesting of the Saphenous Vein is Associated with Impaired Endothelial Function
  The Journal of Thoracic and Cardiovascular Surgery. Jan, 2004  |   Pubmed ID: 14752414
• Effect of Moderate Pressure Distention on the Human Saphenous Vein Vasomotor Function
  The Annals of Thoracic Surgery. Jan, 2004  |   Pubmed ID: 14726044
• Organellar Junctions Promote Targeted Ca2+ Signaling in Smooth Muscle: Why Two Membranes Are Better Than One
  Trends in Pharmacological Sciences. Jan, 2004  |   Pubmed ID: 14723973
• Augmented Contractile Response of Vascular Smooth Muscle in a Diabetic Mouse Model
  Journal of Vascular Research. Nov-Dec, 2003  |   Pubmed ID: 14646372
• Relationship Between Asynchronous Ca2+ Waves and Force Development in Intact Smooth Muscle Bundles of the Porcine Trachea
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2003  |   Pubmed ID: 12936908
• Histamine-induced Ca(2+) Signaling in Human Valvular Myofibroblasts
  Journal of Molecular and Cellular Cardiology. Apr, 2003  |   Pubmed ID: 12689817
• Agonist-induced Mitochondrial Ca2+ Transients in Smooth Muscle
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2003  |   Pubmed ID: 12522109
• Simultaneous in Situ Monitoring of Intracellular Ca2+ and NO in Endothelium of Coronary Arteries
  American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2002  |   Pubmed ID: 12388315
• In the Presence of L-NAME SERCA Blockade Induces Endothelium-dependent Contraction of Mouse Aorta Through Activation of Smooth Muscle Prostaglandin H2/thromboxane A2 Receptors
  British Journal of Pharmacology. Oct, 2002  |   Pubmed ID: 12359637
• The Mechanism of Excitation-contraction Coupling in Phenylephrine-stimulated Human Saphenous Vein
  American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2002  |   Pubmed ID: 12234776
• Relationship Between the Sarcoplasmic Reticulum and the Plasma Membrane
  Novartis Foundation Symposium. 2002  |   Pubmed ID: 12164314
• Sequential Opening of IP(3)-sensitive Ca(2+) Channels and SOC During Alpha-adrenergic Activation of Rabbit Vena Cava
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2002  |   Pubmed ID: 11959642
• Ca(2+) Oscillations, Gradients, and Homeostasis in Vascular Smooth Muscle
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2002  |   Pubmed ID: 11959618
• Raloxifene Enhances Nitric Oxide Release in Rat Aorta Via Increasing Endothelial Nitric Oxide MRNA Expression
  European Journal of Pharmacology. Jan, 2002  |   Pubmed ID: 11779577