Darragh Duffy Immunobiology of Dendritic Cells Institut Pasteur Biography Publications Institution JoVE Articles Darragh Duffy has not added a biography. If you are Darragh Duffy and would like to personalize this page please email our Author Liaison for assistance. Publications Comment On: 'Aberrant TRNA Processing Causes an Autoinflammatory Syndrome Responsive to TNF Inhibitors' by Giannelou : Mutations in Result in a Constitutive Activation of Type I Interferon Signalling Annals of the Rheumatic Diseases. Jun, 2018 | Pubmed ID: 29858171 JAK Inhibitor Improves Type I Interferon Induced Damage: Proof of Concept in Dermatomyositis Brain : a Journal of Neurology. Jun, 2018 | Pubmed ID: 29741608 Publisher Correction: Natural Variation in the Parameters of Innate Immune Cells is Preferentially Driven by Genetic Factors Nature Immunology. Jun, 2018 | Pubmed ID: 29725081 Milieu Intérieur: Defining the Boundaries of a Healthy Immune Response for Improved Vaccination Strategies Human Vaccines & Immunotherapeutics. May, 2018 | Pubmed ID: 29714672 Development and Clinical Validation of the Genedrive Point-of-care Test for Qualitative Detection of Hepatitis C Virus Gut. Apr, 2018 | Pubmed ID: 29615488 T-cell Biomarkers for Diagnosis of Tuberculosis: Candidate Evaluation by a Simple Whole Blood Assay for Clinical Translation The European Respiratory Journal. Mar, 2018 | Pubmed ID: 29567725 Natural Variation in the Parameters of Innate Immune Cells is Preferentially Driven by Genetic Factors Nature Immunology. Mar, 2018 | Pubmed ID: 29476184 Distinctive Roles of Age, Sex, and Genetics in Shaping Transcriptional Variation of Human Immune Responses to Microbial Challenges Proceedings of the National Academy of Sciences of the United States of America. Jan, 2018 | Pubmed ID: 29282317 Myogenic Progenitor Cells Exhibit Type I Interferon-Driven Proangiogenic Properties and Molecular Signature During Juvenile Dermatomyositis Arthritis & Rheumatology (Hoboken, N.J.). Jan, 2018 | Pubmed ID: 28941175 Study of the Humoral Immune Response Towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay High-throughput. Oct, 2017 | Pubmed ID: 29855459 Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response Against the Six Pathogens HAV, HBV, HCV, CMV, T. Gondii, and H. Pylori High-throughput. Oct, 2017 | Pubmed ID: 29855458 Type I Interferon-mediated Autoinflammation Due to DNase II Deficiency Nature Communications. Dec, 2017 | Pubmed ID: 29259162 Standardized Whole Blood Stimulation Improves Immunomonitoring of Induced Immune Responses in Multi-center Study Clinical Immunology (Orlando, Fla.). 10, 2017 | Pubmed ID: 28943400 An in Vitro Diagnostic Certified Point of Care Single Nucleotide Test for IL28B Polymorphisms PloS One. 2017 | Pubmed ID: 28877177 Deconvolution of the Response to Bacillus Calmette-Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity Frontiers in Immunology. 2017 | Pubmed ID: 28751891 Brief Report: Blockade of TANK-Binding Kinase 1/IKKɛ Inhibits Mutant Stimulator of Interferon Genes (STING)-Mediated Inflammatory Responses in Human Peripheral Blood Mononuclear Cells Arthritis & Rheumatology (Hoboken, N.J.). 07, 2017 | Pubmed ID: 28426911 Detection of Interferon Alpha Protein Reveals Differential Levels and Cellular Sources in Disease The Journal of Experimental Medicine. May, 2017 | Pubmed ID: 28420733 Ultrasensitive HIV-1 P24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents Journal of Virology. 03, 2017 | Pubmed ID: 28077644 Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations Cell. Oct, 2016 | Pubmed ID: 27768888 Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses Cell Reports. Sep, 2016 | Pubmed ID: 27568558 Efficacy of the Janus Kinase 1/2 Inhibitor Ruxolitinib in the Treatment of Vasculopathy Associated with TMEM173-activating Mutations in 3 Children The Journal of Allergy and Clinical Immunology. Dec, 2016 | Pubmed ID: 27554814 Inhibition of DPP4 Activity in Humans Establishes Its In vivo Role in CXCL10 Post-translational Modification: Prospective Placebo-controlled Clinical Studies EMBO Molecular Medicine. 06, 2016 | Pubmed ID: 27137491 Protein Biomarkers Discriminate Leishmania Major-infected and Non-infected Individuals in Areas Endemic for Cutaneous Leishmaniasis BMC Infectious Diseases. Mar, 2016 | Pubmed ID: 27009263 Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study PloS One. 2015 | Pubmed ID: 26670100 Bystander Hyperactivation of Preimmune CD8+ T Cells in Chronic HCV Patients ELife. Nov, 2015 | Pubmed ID: 26568315 Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy PloS One. 2015 | Pubmed ID: 26181438 Automated Flow Cytometric Analysis Across Large Numbers of Samples and Cell Types Clinical Immunology (Orlando, Fla.). Apr, 2015 | Pubmed ID: 25576660 Semi-automated and Standardized Cytometric Procedures for Multi-panel and Multi-parametric Whole Blood Immunophenotyping Clinical Immunology (Orlando, Fla.). Apr, 2015 | Pubmed ID: 25572534 The Milieu Intérieur Study - an Integrative Approach for Study of Human Immunological Variance Clinical Immunology (Orlando, Fla.). Apr, 2015 | Pubmed ID: 25562703 Apolipoprotein H Expression is Associated with IL28B Genotype and Viral Clearance in Hepatitis C Virus Infection Journal of Hepatology. Oct, 2014 | Pubmed ID: 24905490 Functional Analysis Via Standardized Whole-blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli Immunity. Mar, 2014 | Pubmed ID: 24656047 The ABCs of Viral Hepatitis That Define Biomarker Signatures of Acute Viral Hepatitis Hepatology (Baltimore, Md.). Apr, 2014 | Pubmed ID: 24500966 CXCL10 Antagonism and Plasma SDPPIV Correlate with Increasing Liver Disease in Chronic HCV Genotype 4 Infected Patients Cytokine. Aug, 2013 | Pubmed ID: 23664274 Développement et Validation d’une seule molécule ultrasensible de tableau numérique Enzyme-linked Immunosorbent Assay for Human interféron-α Alba Llibre*1,2, Vincent Bondet*1,2, Mathieu P. Rodero3, David Hunt4, Yanick J. Crow3,5, Darragh Duffy1,2 1Immunobiology of Dendritic Cells, Institut Pasteur, 2INSERM U1223, 3Laboratory of Neurogenetics and Neuroinflammation, INSERM UMR1163, Institut Imagine, 4MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, 5Manchester Centre for Genomic Medicine, University of Manchester JoVE 57421 Immunology and Infection
Développement et Validation d’une seule molécule ultrasensible de tableau numérique Enzyme-linked Immunosorbent Assay for Human interféron-α Alba Llibre*1,2, Vincent Bondet*1,2, Mathieu P. Rodero3, David Hunt4, Yanick J. Crow3,5, Darragh Duffy1,2 1Immunobiology of Dendritic Cells, Institut Pasteur, 2INSERM U1223, 3Laboratory of Neurogenetics and Neuroinflammation, INSERM UMR1163, Institut Imagine, 4MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, 5Manchester Centre for Genomic Medicine, University of Manchester JoVE 57421 Immunology and Infection