David A. Hood

Publications

• P53 Regulates Skeletal Muscle Mitophagy and Mitochondrial Quality Control Following Denervation-induced Muscle Disuse
  The Journal of Biological Chemistry. Dec, 2021  |   Pubmed ID: 34958797
• Human Cardiac Ischemia-reperfusion Injury: Blunted Stress Response with Age
  Journal of Cardiac Surgery. Oct, 2021  |   Pubmed ID: 34250631
• Effect of Rapamycin on Mitochondria and Lysosomes in Fibroblasts from Patients with MtDNA Mutations
  American Journal of Physiology. Cell Physiology. 07, 2021  |   Pubmed ID: 34106788
• Mitochondrial Bioenergetics and Turnover During Chronic Muscle Disuse
  International Journal of Molecular Sciences. May, 2021  |   Pubmed ID: 34068411
• Examining Interindividual Differences in Select Muscle and Whole-body Adaptations to Continuous Endurance Training
  Experimental Physiology. Nov, 2021  |   Pubmed ID: 33998072
• Manifestations of Age on Autophagy, Mitophagy and Lysosomes in Skeletal Muscle
  Cells. 04, 2021  |   Pubmed ID: 33946883
• Exercise Is Muscle Mitochondrial Medicine
  Exercise and Sport Sciences Reviews. 04, 2021  |   Pubmed ID: 33720909
• Exercise and Mitochondrial Health
  The Journal of Physiology. 02, 2021  |   Pubmed ID: 31674658
• Molecular Basis for the Therapeutic Effects of Exercise on Mitochondrial Defects
  Frontiers in Physiology. 2020  |   Pubmed ID: 33584337
• Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults
  Cells. 12, 2020  |   Pubmed ID: 33276460
• The Intersection of Exercise and Aging on Mitochondrial Protein Quality Control
  Experimental Gerontology. 03, 2020  |   Pubmed ID: 31911185
• Looking Beyond PGC-1α: Emerging Regulators of Exercise-induced Skeletal Muscle Mitochondrial Biogenesis and Their Activation by Dietary Compounds
  Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Jan, 2020  |   Pubmed ID: 31158323
• Mitochondrial Breakdown in Skeletal Muscle and the Emerging Role of the Lysosomes
  Archives of Biochemistry and Biophysics. 01, 2019  |   Pubmed ID: 30439362
• Regulation of Autophagic and Mitophagic Flux During Chronic Contractile Activity-induced Muscle Adaptations
  Pflugers Archiv : European Journal of Physiology. 03, 2019  |   Pubmed ID: 30368578
• Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging
  Annual Review of Physiology. 02, 2019  |   Pubmed ID: 30216742
• The Role of P53 in Determining Mitochondrial Adaptations to Endurance Training in Skeletal Muscle
  Scientific Reports. 10, 2018  |   Pubmed ID: 30279494
• Contractile Activity Attenuates Autophagy Suppression and Reverses Mitochondrial Defects in Skeletal Muscle Cells
  Autophagy. 2018  |   Pubmed ID: 30078345
• Effect of Tim23 Knockdown in Vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPR in Muscle
  American Journal of Physiology. Cell Physiology. 10, 2018  |   Pubmed ID: 29949403
• Parkin is Required for Exercise-induced Mitophagy in Muscle: Impact of Aging
  American Journal of Physiology. Endocrinology and Metabolism. 09, 2018  |   Pubmed ID: 29812989
• Autophagy and Mitophagy Flux in Young and Aged Skeletal Muscle Following Chronic Contractile Activity
  The Journal of Physiology. 08, 2018  |   Pubmed ID: 29781176
• Role of Parkin and Endurance Training on Mitochondrial Turnover in Skeletal Muscle
  Skeletal Muscle. 03, 2018  |   Pubmed ID: 29549884
• Effect of Contractile Activity on PGC-1α Transcription in Young and Aged Skeletal Muscle
  Journal of Applied Physiology (Bethesda, Md. : 1985). 06, 2018  |   Pubmed ID: 29543139
• A Systematic Review of P53 Regulation of Oxidative Stress in Skeletal Muscle
  Redox Report : Communications in Free Radical Research. Dec, 2018  |   Pubmed ID: 29298131
• Exercise Induces TFEB Expression and Activity in Skeletal Muscle in a PGC-1α-dependent Manner
  American Journal of Physiology. Cell Physiology. Jan, 2018  |   Pubmed ID: 29046293
• Regulation of the Autophagy System During Chronic Contractile Activity-induced Muscle Adaptations
  Physiological Reports. Jul, 2017  |   Pubmed ID: 28720712
• Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle
  Oxidative Medicine and Cellular Longevity. 2017  |   Pubmed ID: 28656072
• The Unfolded Protein Response in Relation to Mitochondrial Biogenesis in Skeletal Muscle Cells
  American Journal of Physiology. Cell Physiology. May, 2017  |   Pubmed ID: 28274921
• The Analysis of Knee Joint Loading During Drop Landing from Different Heights and Under Different Instruction Sets in Healthy Males
  Sports Medicine - Open. Dec, 2017  |   Pubmed ID: 28101732
• Function of Specialized Regulatory Proteins and Signaling Pathways in Exercise-induced Muscle Mitochondrial Biogenesis
  Integrative Medicine Research. Sep, 2016  |   Pubmed ID: 28462117
• The Role of Nrf2 in Skeletal Muscle Contractile and Mitochondrial Function
  Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2016  |   Pubmed ID: 27471236
• Unravelling the Mechanisms Regulating Muscle Mitochondrial Biogenesis
  The Biochemical Journal. 08, 2016  |   Pubmed ID: 27470593
• Chronology of UPR Activation in Skeletal Muscle Adaptations to Chronic Contractile Activity
  American Journal of Physiology. Cell Physiology. Jun, 2016  |   Pubmed ID: 27122157
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition)
  Autophagy. Jan, 2016  |   Pubmed ID: 26799652
• The Regulation of Autophagy During Exercise in Skeletal Muscle
  Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2016  |   Pubmed ID: 26679612
• Exercise and the Regulation of Mitochondrial Turnover
  Progress in Molecular Biology and Translational Science. 2015  |   Pubmed ID: 26477912
• The Regulation of Mitochondrial Transcription Factor A (Tfam) Expression During Skeletal Muscle Cell Differentiation
  Bioscience Reports. May, 2015  |   Pubmed ID: 26182383
• Effect of Denervation on the Regulation of Mitochondrial Transcription Factor A Expression in Skeletal Muscle
  American Journal of Physiology. Cell Physiology. Aug, 2015  |   Pubmed ID: 26063705
• Mitochondria, Muscle Health, and Exercise with Advancing Age
  Physiology (Bethesda, Md.). May, 2015  |   Pubmed ID: 25933821
• PGC-1α Modulates Denervation-induced Mitophagy in Skeletal Muscle
  Skeletal Muscle. 2015  |   Pubmed ID: 25834726
• Role of PGC-1α During Acute Exercise-induced Autophagy and Mitophagy in Skeletal Muscle
  American Journal of Physiology. Cell Physiology. May, 2015  |   Pubmed ID: 25673772
• Effect of P53 on Mitochondrial Morphology, Import, and Assembly in Skeletal Muscle
  American Journal of Physiology. Cell Physiology. Feb, 2015  |   Pubmed ID: 25472962
• Recent Advances in Mitochondrial Turnover During Chronic Muscle Disuse
  Integrative Medicine Research. Dec, 2014  |   Pubmed ID: 28664093
• Cytoskeletal Regulation of Mitochondrial Movements in Myoblasts
  Cytoskeleton (Hoboken, N.J.). Oct, 2014  |   Pubmed ID: 25147078
• Multiple Signaling Pathways Regulate Contractile Activity-mediated PGC-1α Gene Expression and Activity in Skeletal Muscle Cells
  Physiological Reports. May, 2014  |   Pubmed ID: 24843073
• Oxidative Stress-induced Mitochondrial Fragmentation and Movement in Skeletal Muscle Myoblasts
  American Journal of Physiology. Cell Physiology. Jun, 2014  |   Pubmed ID: 24740540
• P53 is Necessary for the Adaptive Changes in Cellular Milieu Subsequent to an Acute Bout of Endurance Exercise
  American Journal of Physiology. Cell Physiology. Feb, 2014  |   Pubmed ID: 24284795
• Altered Mitochondrial Morphology and Defective Protein Import Reveal Novel Roles for Bax And/or Bak in Skeletal Muscle
  American Journal of Physiology. Cell Physiology. Sep, 2013  |   Pubmed ID: 23784543
• Acute Exercise Induces Tumour Suppressor Protein P53 Translocation to the Mitochondria and Promotes a P53-Tfam-mitochondrial DNA Complex in Skeletal Muscle
  The Journal of Physiology. Jul, 2013  |   Pubmed ID: 23690562
• Expression of Mitochondrial Fission and Fusion Regulatory Proteins in Skeletal Muscle During Chronic Use and Disuse
  Muscle & Nerve. Dec, 2013  |   Pubmed ID: 23494933
• Endurance Training Ameliorates the Metabolic and Performance Characteristics of Circadian Clock Mutant Mice
  Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2013  |   Pubmed ID: 23429867
• Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23329826
• The Effects of Chronic Muscle Use and Disuse on Cardiolipin Metabolism
  Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2013  |   Pubmed ID: 23221956
• Adaptive Plasticity of Autophagic Proteins to Denervation in Aging Skeletal Muscle
  American Journal of Physiology. Cell Physiology. Mar, 2013  |   Pubmed ID: 23220115
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy
  Autophagy. Apr, 2012  |   Pubmed ID: 22966490
• MRNA Stability As a Function of Striated Muscle Oxidative Capacity
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2012  |   Pubmed ID: 22718808
• Denervation-induced Mitochondrial Dysfunction and Autophagy in Skeletal Muscle of Apoptosis-deficient Animals
  American Journal of Physiology. Cell Physiology. Aug, 2012  |   Pubmed ID: 22673615
• Mitochondrial Dysregulation in the Pathogenesis of Diabetes: Potential for Mitochondrial Biogenesis-mediated Interventions
  Experimental Diabetes Research. 2012  |   Pubmed ID: 22203837
• Plasticity of TOM Complex Assembly in Skeletal Muscle Mitochondria in Response to Chronic Contractile Activity
  Mitochondrion. Mar, 2012  |   Pubmed ID: 22142511
• The Role of SirT1 in Muscle Mitochondrial Turnover
  Mitochondrion. Jan, 2012  |   Pubmed ID: 21406254
• Mechanisms of Exercise-induced Mitochondrial Biogenesis in Skeletal Muscle: Implications for Health and Disease
  Comprehensive Physiology. Jul, 2011  |   Pubmed ID: 23733637
• Role of P53 Within the Regulatory Network Controlling Muscle Mitochondrial Biogenesis
  Exercise and Sport Sciences Reviews. Oct, 2011  |   Pubmed ID: 21799424
• Contractile Activity-induced Gene Expression in Fast- and Slow-twitch Muscle
  Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Apr, 2011  |   Pubmed ID: 21609285
• The Importance of PGC-1α in Contractile Activity-induced Mitochondrial Adaptations
  American Journal of Physiology. Endocrinology and Metabolism. Feb, 2011  |   Pubmed ID: 21081705
• Effect of Denervation-induced Muscle Disuse on Mitochondrial Protein Import
  American Journal of Physiology. Cell Physiology. Jan, 2011  |   Pubmed ID: 20943961
• Regulation of PPARγ Coactivator-1α Function and Expression in Muscle: Effect of Exercise
  PPAR Research. 2010  |   Pubmed ID: 20847946
• Effect of Chronic Contractile Activity on MRNA Stability in Skeletal Muscle
  American Journal of Physiology. Cell Physiology. Jul, 2010  |   Pubmed ID: 20375275
• Biogenesis of the Mitochondrial Tom40 Channel in Skeletal Muscle from Aged Animals and Its Adaptability to Chronic Contractile Activity
  American Journal of Physiology. Cell Physiology. Jun, 2010  |   Pubmed ID: 20107041
• Effect of Age on the Processing and Import of Matrix-destined Mitochondrial Proteins in Skeletal Muscle
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2010  |   Pubmed ID: 20045872
• Mitochondrial Dysfunction is Associated with a Pro-apoptotic Cellular Environment in Senescent Cardiac Muscle
  Mechanisms of Ageing and Development. Feb, 2010  |   Pubmed ID: 20036683
• Transcriptional and Post-transcriptional Regulation of Mitochondrial Biogenesis in Skeletal Muscle: Effects of Exercise and Aging
  Biochimica Et Biophysica Acta. Mar, 2010  |   Pubmed ID: 19682549
• Molecular Basis for an Attenuated Mitochondrial Adaptive Plasticity in Aged Skeletal Muscle
  Aging. Sep, 2009  |   Pubmed ID: 20157569
• Relationship Between Sirt1 Expression and Mitochondrial Proteins During Conditions of Chronic Muscle Use and Disuse
  Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2009  |   Pubmed ID: 19797682
• Specific Attenuation of Protein Kinase Phosphorylation in Muscle with a High Mitochondrial Content
  American Journal of Physiology. Endocrinology and Metabolism. Sep, 2009  |   Pubmed ID: 19549794
• Mechanisms of Exercise-induced Mitochondrial Biogenesis in Skeletal Muscle
  Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Jun, 2009  |   Pubmed ID: 19448716
• Diminished Contraction-induced Intracellular Signaling Towards Mitochondrial Biogenesis in Aged Skeletal Muscle
  Aging Cell. Aug, 2009  |   Pubmed ID: 19416128
• Age-associated Mitochondrial Dysfunction in Skeletal Muscle: Contributing Factors and Suggestions for Long-term Interventions
  IUBMB Life. Mar, 2009  |   Pubmed ID: 19243006
• Role of P53 in Mitochondrial Biogenesis and Apoptosis in Skeletal Muscle
  Physiological Genomics. Mar, 2009  |   Pubmed ID: 19106183
• Denervation-induced Oxidative Stress and Autophagy Signaling in Muscle
  Autophagy. Feb, 2009  |   Pubmed ID: 19098460
• Interactions Between ROS and AMP Kinase Activity in the Regulation of PGC-1alpha Transcription in Skeletal Muscle Cells
  American Journal of Physiology. Cell Physiology. Jan, 2009  |   Pubmed ID: 19005163
• AMP-activated Protein Kinase-regulated Activation of the PGC-1alpha Promoter in Skeletal Muscle Cells
  PloS One. 2008  |   Pubmed ID: 18974883
• Kinase-specific Responsiveness to Incremental Contractile Activity in Skeletal Muscle with Low and High Mitochondrial Content
  American Journal of Physiology. Endocrinology and Metabolism. Jul, 2008  |   Pubmed ID: 18492778
• Effect of Prior Chronic Contractile Activity on Mitochondrial Function and Apoptotic Protein Expression in Denervated Muscle
  Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2008  |   Pubmed ID: 18450984
• Mitochondrial Function and Apoptotic Susceptibility in Aging Skeletal Muscle
  Aging Cell. Jan, 2008  |   Pubmed ID: 18028258
• Thyroid Hormone (T3) Rapidly Activates P38 and AMPK in Skeletal Muscle in Vivo
  Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2008  |   Pubmed ID: 17962579
• The Effect of Training on the Expression of Mitochondrial Biogenesis- and Apoptosis-related Proteins in Skeletal Muscle of Patients with MtDNA Defects
  American Journal of Physiology. Endocrinology and Metabolism. Sep, 2007  |   Pubmed ID: 17551003
• Effect of Denervation on Mitochondrially Mediated Apoptosis in Skeletal Muscle
  Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2007  |   Pubmed ID: 17122379
• Effect of Chronic Contractile Activity on SS and IMF Mitochondrial Apoptotic Susceptibility in Skeletal Muscle
  American Journal of Physiology. Endocrinology and Metabolism. Mar, 2007  |   Pubmed ID: 17106065
• Skeletal Muscle Stem Cells: a Symposium
  Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Dec, 2006  |   Pubmed ID: 17213898
• Control of Gene Expression and Mitochondrial Biogenesis in the Muscular Adaptation to Endurance Exercise
  Essays in Biochemistry. 2006  |   Pubmed ID: 17144877
• Coordination of Metabolic Plasticity in Skeletal Muscle
  The Journal of Experimental Biology. Jun, 2006  |   Pubmed ID: 16731803
• How is Mitochondrial Biogenesis Affected in Mitochondrial Disease?
  Medicine and Science in Sports and Exercise. Dec, 2005  |   Pubmed ID: 16331136
• Mechanisms of Mitochondrial Disease and the Role of Exercise: a Symposium
  Medicine and Science in Sports and Exercise. Dec, 2005  |   Pubmed ID: 16331133
• Application of Animal Models: Chronic Electrical Stimulation-induced Contractile Activity
  Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquee. Oct, 2005  |   Pubmed ID: 16293907
• Differential Susceptibility of Subsarcolemmal and Intermyofibrillar Mitochondria to Apoptotic Stimuli
  American Journal of Physiology. Cell Physiology. Oct, 2005  |   Pubmed ID: 15901602
• Regulation of Egr-1, SRF, and Sp1 MRNA Expression in Contracting Skeletal Muscle Cells
  Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2004  |   Pubmed ID: 15310743
• Mitochondrial Assembly: Protein Import
  The Proceedings of the Nutrition Society. May, 2004  |   Pubmed ID: 15294046
• Role of UCP3 in State 4 Respiration During Contractile Activity-induced Mitochondrial Biogenesis
  Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2004  |   Pubmed ID: 15145919
• Calcium-regulated Changes in Mitochondrial Phenotype in Skeletal Muscle Cells
  American Journal of Physiology. Cell Physiology. May, 2004  |   Pubmed ID: 15075204
• Tissue-specific Regulation of Cytochrome C Oxidase Subunit Expression by Thyroid Hormone
  American Journal of Physiology. Endocrinology and Metabolism. Jun, 2004  |   Pubmed ID: 14970006
• Compensatory Responses of Protein Import and Transcription Factor Expression in Mitochondrial DNA Defects
  American Journal of Physiology. Cell Physiology. Apr, 2004  |   Pubmed ID: 14656719
• Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise
  Sports Medicine (Auckland, N.Z.). 2003  |   Pubmed ID: 12959619
• PPARgamma Coactivator-1alpha Expression During Thyroid Hormone- and Contractile Activity-induced Mitochondrial Adaptations
  American Journal of Physiology. Cell Physiology. Jun, 2003  |   Pubmed ID: 12734114
• Mitochondrial Biogenesis and the Role of the Protein Import Pathway
  Medicine and Science in Sports and Exercise. Jan, 2003  |   Pubmed ID: 12544641
• Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity
  Experimental Physiology. Jan, 2003  |   Pubmed ID: 12525859
• Functional Consequences of Thyroid Hormone-induced Changes in the Mitochondrial Protein Import Pathway
  American Journal of Physiology. Endocrinology and Metabolism. Jan, 2003  |   Pubmed ID: 12388124
• Apoptosis in Heart and Skeletal Muscle
  Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquee. Aug, 2002  |   Pubmed ID: 12442352