David J. Baylink Division of Regenerative Medicine, Department of Medicine Loma Linda University Biography Publications Institution JoVE Articles David J. Baylink has not added a biography. If you are David J. Baylink and would like to personalize this page please email our Author Liaison for assistance. Publications Unique Anabolic Action of Stem Cell Gene Therapy Overexpressing PDGFB-DSS6 Fusion Protein in OVX Osteoporosis Mouse Model Bone Reports. Jun, 2020 | Pubmed ID: 31886323 Mechanistic Study of the Cause of Decreased Blood 1,25-Dihydroxyvitamin D in Sepsis BMC Infectious Diseases. Dec, 2019 | Pubmed ID: 31791247 Towards Clinical Translation of CD8 Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules International Journal of Molecular Sciences. Sep, 2019 | Pubmed ID: 31569411 Cyclooxygenase 2 Augments Osteoblastic but Suppresses Chondrocytic Differentiation of CD90 Skeletal Stem Cells in Fracture Sites Science Advances. 07, 2019 | Pubmed ID: 31392271 In Vivo Generation of Gut-Homing Regulatory T Cells for the Suppression of Colitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2019 | Pubmed ID: 31053627 1,25-Dihydroxyvitamin D Suppresses M1 Macrophages and Promotes M2 Differentiation at Bone Injury Sites JCI Insight. 09, 2018 | Pubmed ID: 30185660 Detection of Dinitrosyl Iron Complexes by Ozone-based Chemiluminescence Nitric Oxide : Biology and Chemistry. 09, 2018 | Pubmed ID: 30059767 Deficient Arginase II Expression Without Alteration in Arginase I Expression Attenuated Experimental Autoimmune Encephalomyelitis in Mice Immunology. 09, 2018 | Pubmed ID: 29574762 Dendritic Cells, Engineered to Overexpress 25-hydroxyvitamin D 1α-hydroxylase and Pulsed with a Myelin Antigen, Provide Myelin-specific Suppression of Ongoing Experimental Allergic Encephalomyelitis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2017 | Pubmed ID: 28363955 Unique Regenerative Mechanism to Replace Bone Lost During Dietary Bone Depletion in Weanling Mice Endocrinology. 04, 2017 | Pubmed ID: 28324039 Effect of Aging on Stem Cells World Journal of Experimental Medicine. Feb, 2017 | Pubmed ID: 28261550 Application of Vitamin D and Vitamin D Analogs in Acute Myelogenous Leukemia Experimental Hematology. Feb, 2017 | Pubmed ID: 28174131 Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis Scientific Reports. Oct, 2016 | Pubmed ID: 27796368 Conditional Deletion of IGF-I in Osteocytes Unexpectedly Accelerates Bony Union of the Fracture Gap in Mice Bone. Nov, 2016 | Pubmed ID: 27519969 Vitamin D Status and Metabolism in an Ovine Pregnancy Model: Effect of Long-term, High-altitude Hypoxia American Journal of Physiology. Endocrinology and Metabolism. Jun, 2016 | Pubmed ID: 27143557 MicroRNA223 Promotes Pathogenic T-cell Development and Autoimmune Inflammation in Central Nervous System in Mice Immunology. Aug, 2016 | Pubmed ID: 27083389 Generation of Mesenchymal Stem Cells by Blood Cell Reprogramming Current Stem Cell Research & Therapy. 2016 | Pubmed ID: 26027679 Patient-specific Cardiovascular Progenitor Cells Derived from Integration-free Induced Pluripotent Stem Cells for Vascular Tissue Regeneration Biomaterials. Dec, 2015 | Pubmed ID: 26398309 PDGFB-based Stem Cell Gene Therapy Increases Bone Strength in the Mouse Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26150503 Osteocyte-derived Insulin-like Growth Factor I is Not Essential for the Bone Repletion Response in Mice PloS One. 2015 | Pubmed ID: 25635763 Targeted 25-hydroxyvitamin D3 1α-hydroxylase Adoptive Gene Therapy Ameliorates Dss-induced Colitis Without Causing Hypercalcemia in Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2015 | Pubmed ID: 25327179 Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone Journal of Bone Metabolism. Feb, 2014 | Pubmed ID: 24707466 ENU Mutation Mapped to a Distal Region of Chromosome 11 is a Major Determinant of Bone Size Physiological Genomics. Dec, 2013 | Pubmed ID: 24151243 Osteocyte-derived Insulin-like Growth Factor I is Essential for Determining Bone Mechanosensitivity American Journal of Physiology. Endocrinology and Metabolism. Jul, 2013 | Pubmed ID: 23715728 Efficient Generation of Integration-free Ips Cells from Human Adult Peripheral Blood Using BCL-XL Together with Yamanaka Factors PloS One. 2013 | Pubmed ID: 23704989 1,25-Dihydroxyvitamin D3 Suppresses TLR8 Expression and TLR8-mediated Inflammatory Responses in Monocytes in Vitro and Experimental Autoimmune Encephalomyelitis in Vivo PloS One. 2013 | Pubmed ID: 23516559 Rapid and Efficient Reprogramming of Human Fetal and Adult Blood CD34+ Cells into Mesenchymal Stem Cells with a Single Factor Cell Research. May, 2013 | Pubmed ID: 23478301 Cellular and Molecular Mechanisms of Accelerated Fracture Healing by COX2 Gene Therapy: Studies in a Mouse Model of Multiple Fractures Bone. Jan, 2013 | Pubmed ID: 23314071 Disruption of the Insulin-like Growth Factor-1 Gene in Osteocytes Impairs Developmental Bone Growth in Mice Bone. Jan, 2013 | Pubmed ID: 23032105 Transgenic Overexpression of Pregnancy-associated Plasma Protein-A in Skeletal Muscle of Mice Increases Myofiber Size and Central Nucleation in Sedentary Muscle and Promotes Muscle Regeneration in the Injured Muscle Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2012 | Pubmed ID: 22709655 Erythroid Promoter Confines FGF2 Expression to the Marrow After Hematopoietic Stem Cell Gene Therapy and Leads to Enhanced Endosteal Bone Formation PloS One. 2012 | Pubmed ID: 22629419 Targeted Overexpression of Osteoactivin in Cells of Osteoclastic Lineage Promotes Osteoclastic Resorption and Bone Loss in Mice PloS One. 2012 | Pubmed ID: 22536365 Efficient Reprogramming of Human Cord Blood CD34(+) Cells Into Induced Pluripotent Stem Cells With OCT4 and SOX2 Alone Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2012 | Pubmed ID: 22108860 Leptin Receptor (Lepr) is a Negative Modulator of Bone Mechanosensitivity and Genetic Variations in Lepr May Contribute to the Differential Osteogenic Response to Mechanical Stimulation in the C57BL/6J and C3H/HeJ Pair of Mouse Strains The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20851886 Prevention of Colorectal Cancer with Vitamin D Scandinavian Journal of Gastroenterology. Aug, 2010 | Pubmed ID: 20367197 Retroviral-based Gene Therapy with Cyclooxygenase-2 Promotes the Union of Bony Callus Tissues and Accelerates Fracture Healing in the Rat The Journal of Gene Medicine. Mar, 2008 | Pubmed ID: 18088065 Conditional Deletion of Insulin-like Growth Factor-I in Collagen Type 1alpha2-expressing Cells Results in Postnatal Lethality and a Dramatic Reduction in Bone Accretion Endocrinology. Dec, 2007 | Pubmed ID: 17717052 Disruption of Insulin-like Growth Factor-I Expression in Type IIalphaI Collagen-expressing Cells Reduces Bone Length and Width in Mice Physiological Genomics. Aug, 2007 | Pubmed ID: 17519362 Identification of Mouse Duffy Antigen Receptor for Chemokines (Darc) As a BMD QTL Gene Genome Research. May, 2007 | Pubmed ID: 17416748 Pregnancy-associated Plasma Protein-A Increases Osteoblast Proliferation in Vitro and Bone Formation in Vivo Endocrinology. Dec, 2006 | Pubmed ID: 16946002 Whole Genome Microarray Analysis of Growth Hormone-induced Gene Expression in Bone: T-box3, a Novel Transcription Factor, Regulates Osteoblast Proliferation American Journal of Physiology. Endocrinology and Metabolism. Jul, 2006 | Pubmed ID: 16464905 Up-regulation of the Wnt, Estrogen Receptor, Insulin-like Growth Factor-I, and Bone Morphogenetic Protein Pathways in C57BL/6J Osteoblasts As Opposed to C3H/HeJ Osteoblasts in Part Contributes to the Differential Anabolic Response to Fluid Shear The Journal of Biological Chemistry. Apr, 2006 | Pubmed ID: 16461770 Identification and Characterization of Novel IGFBP5 Interacting Protein: Evidence IGFBP5-IP is a Potential Regulator of Osteoblast Cell Proliferation American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16269403 Pregnancy-associated Plasma Protein-A Regulates Myoblast Proliferation and Differentiation Through an Insulin-like Growth Factor-dependent Mechanism The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16115888 Ras-association Domain Family 1 Protein, RASSF1C, is an IGFBP-5 Binding Partner and a Potential Regulator of Osteoblast Cell Proliferation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2005 | Pubmed ID: 16007340 Clinical Use of Serum and Urine Bone Markers in the Management of Osteoporosis Current Medical Research and Opinion. Jul, 2005 | Pubmed ID: 16004668 Bayesian Shrinkage Estimation of Quantitative Trait Loci Parameters Genetics. May, 2005 | Pubmed ID: 15781696 Genetic Variation in Femur Extrinsic Strength in 29 Different Inbred Strains of Mice is Dependent on Variations in Femur Cross-sectional Geometry and Bone Density Bone. Jan, 2005 | Pubmed ID: 15664009 Insulin-like Growth Factor-binding Protein-5 Induces a Gender-related Decrease in Bone Mineral Density in Transgenic Mice Endocrinology. Feb, 2005 | Pubmed ID: 15550514 The Multi-functional Role of Insulin-like Growth Factor Binding Proteins in Bone Pediatric Nephrology (Berlin, Germany). Mar, 2005 | Pubmed ID: 15549410 Extracellular Signal-regulated Kinase-1 and -2 Are Both Essential for the Shear Stress-induced Human Osteoblast Proliferation Bone. Aug, 2004 | Pubmed ID: 15268905 Progress Toward Skeletal Gene Therapy Critical Reviews in Eukaryotic Gene Expression. 2004 | Pubmed ID: 15104530 Local Ex Vivo Gene Therapy with Bone Marrow Stromal Cells Expressing Human BMP4 Promotes Endosteal Bone Formation in Mice The Journal of Gene Medicine. Jan, 2004 | Pubmed ID: 14716672 Patients with Van Buchem Disease, an Osteosclerotic Genetic Disease, Have Elevated Bone Formation Markers, Higher Bone Density, and Greater Derived Polar Moment of Inertia Than Normal The Journal of Clinical Endocrinology and Metabolism. Dec, 2003 | Pubmed ID: 14671168 Expression of a Structurally Unique Osteoclastic Protein-tyrosine Phosphatase is Driven by an Alternative Intronic, Cell Type-specific Promoter The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12949066 Evidence That Sensitivity to Growth Hormone (GH) is Growth Period and Tissue Type Dependent: Studies in GH-deficient Lit/lit Mice Endocrinology. Sep, 2003 | Pubmed ID: 12933669 Mapping Quantitative Trait Loci That Influence Serum Insulin-like Growth Factor Binding Protein-5 Levels in F2 Mice (MRL/MpJ X SJL/J) Endocrinology. Aug, 2003 | Pubmed ID: 12865330 In Vivo Bone Formation in Fracture Repair Induced by Direct Retroviral-based Gene Therapy with Bone Morphogenetic Protein-4 Bone. Jun, 2003 | Pubmed ID: 12810166 Analytical and Clinical Evaluation of the Bio-Rad HPLC Kit for Measurement of Type I Collagen Cross Links Journal of Bone and Mineral Metabolism. 2003 | Pubmed ID: 12720047 Fluid Flow Shear Stress Stimulates Human Osteoblast Proliferation and Differentiation Through Multiple Interacting and Competing Signal Transduction Pathways Bone. Mar, 2003 | Pubmed ID: 12667551 Insulin-like Growth Factor Regulates Peak Bone Mineral Density in Mice by Both Growth Hormone-dependent and -independent Mechanisms Endocrinology. Mar, 2003 | Pubmed ID: 12586770 Quantitative Trait Loci That Harbor Genes Regulating Muscle Size in (MRL/MPJ X SJL/J) F(2) Mice Functional & Integrative Genomics. Aug, 2002 | Pubmed ID: 12185459 Quantitative Trait Loci (QTL) for Lean Body Mass and Body Length in MRL/MPJ and SJL/J F(2) Mice Functional & Integrative Genomics. Aug, 2002 | Pubmed ID: 12185457 Genetic Dissection of Femur Breaking Strength in a Large Population (MRL/MpJ X SJL/J) of F2 Mice: Single QTL Effects, Epistasis, and Pleiotropy Genomics. May, 2002 | Pubmed ID: 11991724 DNA Microarrays: Their Use and Misuse Microcirculation (New York, N.Y. : 1994). Jan, 2002 | Pubmed ID: 11896556 Development of a Synthetic Peptide-based Tartrate-resistant Acid Phosphatase Radioimmunoassay for the Measurement of Bone Resorption in Rat Serum Journal of Bone and Mineral Metabolism. 2002 | Pubmed ID: 11862527 Identification of Wound Healing/regeneration Quantitative Trait Loci (QTL) at Multiple Time Points That Explain Seventy Percent of Variance in (MRL/MpJ and SJL/J) Mice F2 Population Genome Research. Dec, 2001 | Pubmed ID: 11731492 Evidence That IGF-binding Protein-5 Functions As a Growth Factor The Journal of Clinical Investigation. Jan, 2001 | Pubmed ID: 11134182 Estrogen Receptor Specificity in the Regulation of Skeletal Growth and Maturation in Male Mice Proceedings of the National Academy of Sciences of the United States of America. May, 2000 | Pubmed ID: 10805804 आंत-होमिंग नियामक टी सेल इंडक्शन के वीवो आवर्धन में Hongzheng Bi1,2, Samiksha Wasnik1, David J. Baylink1, Chenfan Liu1,3,4, Xiaolei Tang1,3 1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University JoVE 60585 Immunology and Infection
आंत-होमिंग नियामक टी सेल इंडक्शन के वीवो आवर्धन में Hongzheng Bi1,2, Samiksha Wasnik1, David J. Baylink1, Chenfan Liu1,3,4, Xiaolei Tang1,3 1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University JoVE 60585 Immunology and Infection
